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TNSN95062A1 - Nouveaux derives dialkoxy-pyridinyle-benzimidazole - Google Patents

Nouveaux derives dialkoxy-pyridinyle-benzimidazole

Info

Publication number
TNSN95062A1
TNSN95062A1 TNTNSN95062A TNSN95062A TNSN95062A1 TN SN95062 A1 TNSN95062 A1 TN SN95062A1 TN TNSN95062 A TNTNSN95062 A TN TNSN95062A TN SN95062 A TNSN95062 A TN SN95062A TN SN95062 A1 TNSN95062 A1 TN SN95062A1
Authority
TN
Tunisia
Prior art keywords
compounds
methyl
pyridinyle
dialkoxy
new
Prior art date
Application number
TNTNSN95062A
Other languages
English (en)
Inventor
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Unge Per Oskar Sverker Von
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of TNSN95062A1 publication Critical patent/TNSN95062A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LES COMPOSES NOUVEAUX OPTIQUEMENT PURS, SOIT, LES COMPOSES ENANTIOMERES SIMPLES (+)-5-CARBOMETHOXY-6-METHYL-2-[[(3,4-DIMETHOXY-2- PYRIDINYL) METHYL] SULFINYL] -1-H- BENZIMIDAZOLE ET (-) -5- CARBOMETHOXY-6-METHYL-2- [[(3,4-DIMETHOXY-2- PYRIDINYL) METHYL] SULFINYL] -1H-BENZIMIDAZOLE, OU DES SELS THERAPEUTIQUEMENT ACCEPTABLES DE CEUX-CI TELS QUE SELS NA+, Mg2+, Li+, K+, Ca2+ ET N+(R4), OU R EST UN GROUPE ALKYLE AVEC 1 A 4 ATOMES DE CARBONE, DES PROCEDES POUR LEUR PREPARATION ET DES PREPARATIONS PHARMACEUTIQUES CONTENANT LES COMPOSES COMME INGREDIENTS ACTIFS, AINSI QUE L'EMPLOI DES COMPOSES DANS DES PREPARATIONS PHARMACEUTIQUES, ET LES INTERMEDIAIRES OBTENUS EN PREPARANT LES COMPOSES
TNTNSN95062A 1994-05-27 1994-05-29 Nouveaux derives dialkoxy-pyridinyle-benzimidazole TNSN95062A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9400511 1994-05-27

Publications (1)

Publication Number Publication Date
TNSN95062A1 true TNSN95062A1 (fr) 1996-02-06

Family

ID=20392945

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN95062A TNSN95062A1 (fr) 1994-05-27 1994-05-29 Nouveaux derives dialkoxy-pyridinyle-benzimidazole

Country Status (18)

Country Link
EP (1) EP0712401A1 (fr)
JP (1) JPH09504557A (fr)
CN (1) CN1128997A (fr)
AU (1) AU2633095A (fr)
BR (1) BR9506235A (fr)
CA (1) CA2166988A1 (fr)
CZ (1) CZ24396A3 (fr)
EE (1) EE9600011A (fr)
FI (1) FI960367A (fr)
HU (1) HU9600005D0 (fr)
IL (1) IL113604A0 (fr)
IS (1) IS4321A (fr)
MA (1) MA23563A1 (fr)
NO (1) NO960268L (fr)
PL (1) PL312692A1 (fr)
TN (1) TNSN95062A1 (fr)
WO (1) WO1995032959A1 (fr)
ZA (1) ZA954125B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
BR9915421A (pt) * 1998-11-18 2001-08-07 Astrazeneca Ab Processo para a fabricação de sais alcalinos levemente solúveis ou menos solúveis de heterociclos de sulfinila substituìda, forma de dosagem farmacêutica, uso da mesma, método de tratamento de doenças gastrointestinais, e, processo para a fabricação de uma forma de dosagem farmacêutica.
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20080103169A1 (en) 2006-10-27 2008-05-01 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
US8247440B2 (en) 2008-02-20 2012-08-21 Curators Of The University Of Missouri Composition comprising omeprazole, lansoprazole and at least one buffering agent
CN102209529A (zh) 2008-09-09 2011-10-05 阿斯利康(瑞典)有限公司 将药物组合物递送至有需要的患者的方法
CN102481293A (zh) 2009-06-25 2012-05-30 阿斯利康(瑞典)有限公司 治疗具有发展nsaid-相关的溃疡的风险的患者的方法
EP2797600A4 (fr) 2011-12-28 2015-09-16 Pozen Inc Compositions et procédés d'administration d'oméprazole plus acide acétylsalicylique améliorés

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0593463B1 (fr) * 1990-06-20 1999-09-15 Astra Aktiebolag Derives de dialcoxy-pyridinyle-benzimidazole, procede de preparation et utilisation pharmaceutique de ces derives
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung

Also Published As

Publication number Publication date
FI960367A0 (fi) 1996-01-26
FI960367A (fi) 1996-01-26
NO960268D0 (no) 1996-01-23
EP0712401A1 (fr) 1996-05-22
CZ24396A3 (en) 1996-06-12
EE9600011A (et) 1996-04-15
BR9506235A (pt) 1997-08-12
CN1128997A (zh) 1996-08-14
WO1995032959A1 (fr) 1995-12-07
PL312692A1 (en) 1996-05-13
IL113604A0 (en) 1995-08-31
CA2166988A1 (fr) 1995-12-07
JPH09504557A (ja) 1997-05-06
HU9600005D0 (en) 1996-03-28
MA23563A1 (fr) 1995-12-31
IS4321A (is) 1996-01-17
AU2633095A (en) 1995-12-21
NO960268L (no) 1996-01-23
ZA954125B (en) 1995-11-27

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