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TN2011000592A1 - Substituted aminopropionic derivatives as neprilysin inhibitors - Google Patents

Substituted aminopropionic derivatives as neprilysin inhibitors

Info

Publication number
TN2011000592A1
TN2011000592A1 TNP2011000592A TN2011000592A TN2011000592A1 TN 2011000592 A1 TN2011000592 A1 TN 2011000592A1 TN P2011000592 A TNP2011000592 A TN P2011000592A TN 2011000592 A TN2011000592 A TN 2011000592A TN 2011000592 A1 TN2011000592 A1 TN 2011000592A1
Authority
TN
Tunisia
Prior art keywords
neprilysin inhibitors
substituted aminopropionic
derivatives
aminopropionic derivatives
substituted
Prior art date
Application number
TNP2011000592A
Inventor
Gary Mark Coppola
Yuki Iwaki
Rajeshri Ganesh Karki
Toshio Kawanami
Gary Michael Ksander
Muneto Mogi
Original Assignee
Novartis Ag
Sun Robert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2010/057247 external-priority patent/WO2010136493A1/en
Application filed by Novartis Ag, Sun Robert filed Critical Novartis Ag
Publication of TN2011000592A1 publication Critical patent/TN2011000592A1/en

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides a compound of formula I' or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
TNP2011000592A 2009-05-28 2011-11-21 Substituted aminopropionic derivatives as neprilysin inhibitors TN2011000592A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18175609P 2009-05-28 2009-05-28
PCT/EP2010/057247 WO2010136493A1 (en) 2009-05-28 2010-05-26 Substituted aminopropionic derivatives as neprilysin inhibitors

Publications (1)

Publication Number Publication Date
TN2011000592A1 true TN2011000592A1 (en) 2013-05-24

Family

ID=52682159

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2011000592A TN2011000592A1 (en) 2009-05-28 2011-11-21 Substituted aminopropionic derivatives as neprilysin inhibitors

Country Status (2)

Country Link
TN (1) TN2011000592A1 (en)
UA (1) UA106233C2 (en)

Also Published As

Publication number Publication date
UA106233C2 (en) 2014-08-11

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