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SV2003000995A - NEW ARILSULFONAMIDS AS ANTIVIRAL AGENTS REF. LEA35214-SV - Google Patents

NEW ARILSULFONAMIDS AS ANTIVIRAL AGENTS REF. LEA35214-SV

Info

Publication number
SV2003000995A
SV2003000995A SV2002000995A SV2002000995A SV2003000995A SV 2003000995 A SV2003000995 A SV 2003000995A SV 2002000995 A SV2002000995 A SV 2002000995A SV 2002000995 A SV2002000995 A SV 2002000995A SV 2003000995 A SV2003000995 A SV 2003000995A
Authority
SV
El Salvador
Prior art keywords
new
antiviral agents
lea35214
arilsulfonamids
agents ref
Prior art date
Application number
SV2002000995A
Other languages
Spanish (es)
Inventor
Wolfgang Bender
Peter Eckenberg
Kerstin Henninger
Jorg Keldenich
Siegfried Raddatz
Gunter Schmidt
Tobias Wunberg
Armin Kern
Jurgen Reefschlager
Holger Zimmermann
Franz Zumpe
Martin Radtke
Sabine Hallenberger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SV2003000995A publication Critical patent/SV2003000995A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NUEVAS ARILSULFONAMIDAS COMO AGENTES ANTIVIRALESLA PRESENTE INVENCIÓN SE REFIERE A NUEVAS SULFONAMIDAS DE FÓRMULA GENERAL (I) (VER FORMULA), EN LA QUE LOS SUSTITUYENTES R1, R2, R3 Y R4, ASÍ COMO A Y X TIENEN LOS SIGNIFICADOS CITADOS, ASÍ COMO A PROCEDIMIENTOS PARA SU PREPARACIÓN Y A SU USO COMO AGENTES ANTIVIRALES, ESPECIALMENTE FRENTE A CITOMEGALOVIRUS.NEW ARILSULPHONAMIDS AS ANTIVIRAL AGENTS THE PRESENT INVENTION REFERS TO NEW SULFONAMIDES OF GENERAL FORMULA (I) (SEE FORMULA), IN WHICH THE SUBSTITUTES R1, R2, R3 AND R4, AS WELL AS AYX HAVE THE MEANINGS AS APPOINTMENT TO PREPARATION AND ITS USE AS ANTIVIRAL AGENTS, ESPECIALLY AGAINST CITOMEGALOVIRUS.

SV2002000995A 2001-04-19 2002-04-18 NEW ARILSULFONAMIDS AS ANTIVIRAL AGENTS REF. LEA35214-SV SV2003000995A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19
DE10148598A DE10148598A1 (en) 2001-04-19 2001-10-02 New N-(acylaminophenyl)-heteroaryl-benzenesulfonamide derivatives, useful as antiviral agents, especially effective against human cytomegalovirus infections

Publications (1)

Publication Number Publication Date
SV2003000995A true SV2003000995A (en) 2003-03-18

Family

ID=7681939

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2002000995A SV2003000995A (en) 2001-04-19 2002-04-18 NEW ARILSULFONAMIDS AS ANTIVIRAL AGENTS REF. LEA35214-SV

Country Status (9)

Country Link
KR (1) KR20030088509A (en)
AR (1) AR034309A1 (en)
CO (1) CO5540388A2 (en)
DE (1) DE10148598A1 (en)
EC (1) ECSP034813A (en)
GT (1) GT200200075A (en)
PE (1) PE20021061A1 (en)
SV (1) SV2003000995A (en)
ZA (1) ZA200307892B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482366B2 (en) * 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
RS20050175A (en) 2002-08-23 2007-09-21 Rigel Pharmaceuticals Inc., Pyridyl substituted heterocycles useful for treating or preventing hcv infection
JP2006516250A (en) * 2002-12-18 2006-06-29 サイトビア インコーポレイティッド 3,5-disubstituted- [1,2,4] -oxadiazoles and their derivatives and their use as caspase activators and apoptosis inducers
DE10300109A1 (en) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Method for inhibiting replication of herpes viruses
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
EP1883633A2 (en) 2005-05-02 2008-02-06 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (en) 2006-12-30 2008-07-31 Abbott Gmbh & Amp OXINDOL DERIVATIVES REPLACED, MEDICINES THAT UNDERSTAND AND USE THEMSELVES
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
US8546401B2 (en) 2007-12-07 2013-10-01 AbbVie Deutschland GmbH & Co. KG 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases
US8703774B2 (en) 2007-12-07 2014-04-22 AbbVie Deutschland GmbH & Co. KG Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
AU2008333123C1 (en) 2007-12-07 2014-06-19 AbbVie Deutschland GmbH & Co. KG 5-halogen-substituted oxindole derivatives and use thereof for treating vasopressine-dependent diseases
ES2398676T3 (en) 2007-12-07 2013-03-20 Abbott Gmbh & Co. Kg Amidomethyl substituted oxindole derivatives and their use for the production of a drug for the treatment of vasopressin-dependent diseases
EP2435080A2 (en) 2009-05-29 2012-04-04 Abbott Laboratories Pharmaceutical compositions for the treatment of pain

Also Published As

Publication number Publication date
AR034309A1 (en) 2004-02-18
ECSP034813A (en) 2003-12-01
GT200200075A (en) 2002-12-24
ZA200307892B (en) 2004-10-11
CO5540388A2 (en) 2005-07-29
PE20021061A1 (en) 2002-12-12
DE10148598A1 (en) 2002-10-24
KR20030088509A (en) 2003-11-19

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