US5919455A
(en)
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
US5951974A
(en)
*
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
CA2236591C
(en)
|
1995-11-02 |
2012-01-03 |
Schering Corporation |
Continuous low-dose cytokine infusion therapy
|
US5908621A
(en)
*
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
US5985263A
(en)
*
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
US5981709A
(en)
*
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
WO1999048535A1
(en)
*
|
1998-03-26 |
1999-09-30 |
Schering Corporation |
Formulations for protection of peg-interferon alpha conjugates
|
US6180096B1
(en)
|
1998-03-26 |
2001-01-30 |
Schering Corporation |
Formulations for protection of peg-interferon alpha conjugates
|
PL196533B1
(pl)
*
|
1998-04-28 |
2008-01-31 |
Applied Research Systems |
Sposób stopniowego przyłączania ugrupowań poli (glikolu etylenowego) (PEG) szeregowo do polipeptydu
|
ATE216591T1
(de)
|
1998-05-15 |
2002-05-15 |
Schering Corp |
Kombinationstherapie enthaltend ribavirin und interferon alpha bei patienten mit chronischer hepatitis c infektion, die nicht antiviral vorbehandelt sind
|
ATE307597T1
(de)
*
|
1998-06-08 |
2005-11-15 |
Hoffmann La Roche |
Verwendung von peg-ifn-alpha und ribavirin zur behandlung chronischer hepatitis c
|
US6277830B1
(en)
*
|
1998-10-16 |
2001-08-21 |
Schering Corporation |
5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
|
IL129299A0
(en)
*
|
1999-03-31 |
2000-02-17 |
Mor Research Applic Ltd |
Monoclonal antibodies antigens and diagnosis of malignant diseases
|
DK1043026T3
(da)
|
1999-04-08 |
2005-07-04 |
Schering Corp |
Melanombehandling
|
US6605273B2
(en)
|
1999-04-08 |
2003-08-12 |
Schering Corporation |
Renal cell carcinoma treatment
|
NZ514417A
(en)
*
|
1999-04-08 |
2003-10-31 |
Schering Corp |
Use of pegylated interferon alpha in chronic myeloid leukemia (CML) therapy
|
US6923966B2
(en)
|
1999-04-08 |
2005-08-02 |
Schering Corporation |
Melanoma therapy
|
US6362162B1
(en)
|
1999-04-08 |
2002-03-26 |
Schering Corporation |
CML Therapy
|
CZ299516B6
(cs)
*
|
1999-07-02 |
2008-08-20 |
F. Hoffmann-La Roche Ag |
Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
|
US6313143B1
(en)
*
|
1999-12-16 |
2001-11-06 |
Hoffmann-La Roche Inc. |
Substituted pyrroles
|
AR027509A1
(es)
|
2000-01-10 |
2003-04-02 |
Maxygen Aps |
Conjugados g-csf
|
AU2001232951A1
(en)
*
|
2000-01-24 |
2001-07-31 |
Schering Corporation |
Combination of temozolomide and pegylated interferon-alpha for treating cancer
|
EP1908477A3
(en)
*
|
2000-01-24 |
2008-06-11 |
Schering Corporation |
Combination of temozolomide and pegylated interferon-alpha for treating cancer
|
EP2319541A1
(en)
|
2000-02-11 |
2011-05-11 |
Bayer HealthCare LLC |
Factor VII or VIIA-like conjugates
|
US6476062B2
(en)
|
2000-03-30 |
2002-11-05 |
Schering Corporation |
Chemokine receptor antagonists
|
US6777387B2
(en)
|
2000-03-31 |
2004-08-17 |
Enzon Pharmaceuticals, Inc. |
Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same
|
US6756037B2
(en)
|
2000-03-31 |
2004-06-29 |
Enzon, Inc. |
Polymer conjugates of biologically active agents and extension moieties for facilitating conjugation of biologically active agents to polymeric terminal groups
|
AU2001255495A1
(en)
|
2000-04-20 |
2001-11-07 |
Schering Corporation |
Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection
|
WO2002002627A2
(en)
|
2000-06-30 |
2002-01-10 |
Zymogenetics, Inc. |
Interferon-like protein zcyto21
|
US7291713B2
(en)
|
2001-01-30 |
2007-11-06 |
Kyowa Hakko Kogyo Co., Ltd. |
Branched polyalkylene glycols
|
MXPA03007619A
(es)
|
2001-02-27 |
2003-12-04 |
Maxygen Aps |
Nuevas moleculas similares a interferon beta.
|
DE10112825A1
(de)
|
2001-03-16 |
2002-10-02 |
Fresenius Kabi De Gmbh |
HESylierung von Wirkstoffen in wässriger Lösung
|
ATE371680T1
(de)
|
2002-01-16 |
2007-09-15 |
Biocompatibles Uk Ltd |
Polymerkonjugate
|
KR100888371B1
(ko)
*
|
2002-01-17 |
2009-03-13 |
동아제약주식회사 |
가지 달린 고분자 유도체와 인터페론 결합체를 포함하는 항바이러스제
|
DE10209822A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
WO2004000366A1
(en)
|
2002-06-21 |
2003-12-31 |
Novo Nordisk Health Care Ag |
Pegylated factor vii glycoforms
|
CA2492775C
(en)
|
2002-07-24 |
2011-06-21 |
F. Hoffmann-La Roche Ag |
Polyalkylene glycol acid additives
|
ES2214166T1
(es)
*
|
2002-09-11 |
2004-09-16 |
Fresenius Kabi Deutschland Gmbh |
Polipeptidos has-ilados, especialmente, eriptropoyetina has-ilada.
|
BR0314227A
(pt)
*
|
2002-09-11 |
2005-10-25 |
Fresenius Kabi De Gmbh |
Derivados de amido de hidroxialquila
|
EP1681303B1
(en)
*
|
2002-09-11 |
2013-09-04 |
Fresenius Kabi Deutschland GmbH |
HASylated polypeptides, especially HASylated erythropoietin
|
DE60323756D1
(de)
|
2002-10-08 |
2008-11-06 |
Fresenius Kabi De Gmbh |
Pharmazeutisch aktive oligosaccharid-conjugate
|
US7314613B2
(en)
|
2002-11-18 |
2008-01-01 |
Maxygen, Inc. |
Interferon-alpha polypeptides and conjugates
|
MXPA05005263A
(es)
*
|
2002-11-18 |
2005-07-25 |
Maxygen Inc |
Polipeptidos y conjugados de interferon alfa.
|
GB0301014D0
(en)
*
|
2003-01-16 |
2003-02-19 |
Biocompatibles Ltd |
Conjugation reactions
|
CA2458085A1
(en)
|
2003-03-21 |
2004-09-21 |
F. Hoffmann-La Roche Ag |
Transcriptional activity assay
|
WO2005014655A2
(en)
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
ATE481420T1
(de)
|
2003-10-10 |
2010-10-15 |
Novo Nordisk As |
Il-21-derivate
|
EP2633866A3
(en)
|
2003-10-17 |
2013-12-18 |
Novo Nordisk A/S |
Combination therapy
|
NZ548256A
(en)
|
2004-02-02 |
2010-02-26 |
Ambrx Inc |
Modified human four helical bundle polypeptides and their uses
|
CN100355784C
(zh)
*
|
2004-02-12 |
2007-12-19 |
江苏恒瑞医药股份有限公司 |
聚乙二醇修饰α-干扰素1b的制备方法
|
EP1725589A1
(en)
|
2004-03-11 |
2006-11-29 |
Fresenius Kabi Deutschland GmbH |
Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
|
CA2566247A1
(en)
|
2004-05-19 |
2005-12-01 |
Maxygen, Inc. |
Interferon-alpha polypeptides and conjugates
|
CN102532321B
(zh)
|
2004-06-18 |
2018-10-12 |
Ambrx公司 |
新颖抗原结合多肽和其用途
|
CA2572751A1
(en)
*
|
2004-06-30 |
2006-01-12 |
Egen Corporation |
Pegylated interferon alpha-1b
|
BRPI0513332A
(pt)
|
2004-08-12 |
2008-05-06 |
Schering Corp |
formulação de interferon peguilado estável
|
CA2594557C
(en)
|
2004-12-22 |
2016-04-26 |
Ambrx, Inc. |
Modified human growth hormone
|
US20060233740A1
(en)
*
|
2005-03-23 |
2006-10-19 |
Bossard Mary J |
Conjugates of an hGH moiety and a polymer
|
KR20080019619A
(ko)
|
2005-05-18 |
2008-03-04 |
맥시겐, 인크. |
개량된 인터페론-알파 폴리펩티드
|
US8633300B2
(en)
|
2005-06-17 |
2014-01-21 |
Novo Nordisk Healthcare Ag |
Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine
|
EP1901777A2
(en)
*
|
2005-06-20 |
2008-03-26 |
Pepgen Corporation |
Low-toxicity, long-circulating chimeras of human interferon-alpha analogs and interferon tau
|
JP4261531B2
(ja)
|
2005-09-06 |
2009-04-30 |
株式会社Nrlファーマ |
ラクトフェリン複合体及びその製造方法
|
AU2006315347A1
(en)
|
2005-11-16 |
2007-05-24 |
Ambrx, Inc. |
Methods and compositions comprising non-natural amino acids
|
CN101002944B
(zh)
*
|
2006-01-17 |
2012-07-25 |
中国科学院过程工程研究所 |
支链聚乙二醇-干扰素结合物及其制备方法
|
CN100475270C
(zh)
|
2006-01-20 |
2009-04-08 |
清华大学 |
一种治疗肿瘤的药物及其应用
|
CN101002945B
(zh)
|
2006-01-20 |
2012-09-05 |
清华大学 |
一种用于肿瘤治疗的新型复合物
|
JPWO2007132882A1
(ja)
|
2006-05-16 |
2009-09-24 |
財団法人 東京都医学研究機構 |
Hcv感染症を治療または予防するための医薬組成物
|
WO2007135182A2
(en)
|
2006-05-24 |
2007-11-29 |
Novo Nordisk Health Care Ag |
Factor ix analogues having prolonged in vivo half life
|
DK2061878T3
(da)
|
2006-09-08 |
2014-04-07 |
Ambrx Inc |
Hybridsuppressor-trna for hvirveldyrceller
|
US8618257B2
(en)
|
2006-09-08 |
2013-12-31 |
Ambrx, Inc. |
Modified human plasma polypeptide or Fc scaffolds and their uses
|
CN1966547B
(zh)
*
|
2006-11-06 |
2011-11-09 |
中国药科大学 |
双链结构的聚乙二醇衍生物的制备及其与药物分子的结合
|
DE602007005165D1
(de)
*
|
2006-11-07 |
2010-04-15 |
Dsm Ip Assets Bv |
Carbamat, thiocarbamat oder carbamid mit einer biomolekularen gruppierung
|
KR101079993B1
(ko)
|
2006-11-17 |
2011-11-04 |
동아제약주식회사 |
폴리에틸렌글리콜 과립구 콜로니 자극인자 접합체
|
CN101219219B
(zh)
|
2007-01-10 |
2013-02-13 |
北京普罗吉生物科技发展有限公司 |
包含血管抑素或其片段的复合物、其制备方法及应用
|
JP5515224B2
(ja)
|
2007-02-28 |
2014-06-11 |
日油株式会社 |
多分岐鎖ポリオキシアルキレン誘導体
|
MX2009010531A
(es)
|
2007-03-30 |
2009-11-26 |
Ambrx Inc |
Polipeptidos de fgf-21 modificados y usos de los mismos.
|
CL2008002399A1
(es)
*
|
2007-08-16 |
2009-01-02 |
Pharmaessentia Corp |
Conjugado sustancialmente puro que posee una porcion polimerica, una porcion proteica (interferon alfa 2b) y un ligante alifatico de 1 a 10 atomos de carbono, util en el tratamiento de las hepatitis b o c.
|
ATE548382T1
(de)
|
2007-09-04 |
2012-03-15 |
Biosteed Gene Expression Tech Co Ltd |
Polyethylenglykolmodifiziertes interferon alpha 2b und herstellungsverfahren und anwendungen davon
|
PT2196475E
(pt)
|
2007-09-04 |
2012-09-07 |
Biosteed Gene Expression Tech Co Ltd |
Interferão alfa-2a modificado por polietilenoglicol, seu processo de síntese e aplicação
|
MX338336B
(es)
|
2007-11-20 |
2016-04-07 |
Ambrx Inc |
Polipeptidos de insulina modificados y sus usos.
|
EP2070950A1
(en)
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Hydroxyalkyl starch derivatives and process for their preparation
|
CA2711375C
(en)
*
|
2008-01-18 |
2019-04-16 |
F. Hoffmann-La Roche Ag |
Purification of not-glycosylated polypeptides
|
CN101980725B
(zh)
*
|
2008-02-01 |
2013-06-12 |
阿森迪斯药物股份有限公司 |
包含可自裂解的连接体的前药
|
EP2247743B1
(en)
|
2008-02-08 |
2016-04-06 |
Ambrx, Inc. |
Modified leptin polypeptides and their uses
|
BRPI0822530B1
(pt)
|
2008-04-03 |
2022-03-22 |
Biosteed Gene Expression Tech. Co., Ltd |
Método de preparação de um hormônio de crescimento humano glicolado por polietileno (modificado por peg), hormônio do crescimento humano modificado por peg de menor peso molecular aparente e seu uso, preparação de hormônio do crescimento humano modificado por peg de menor peso molecular aparente e seu método de preparação e composição
|
LT2279007T
(lt)
|
2008-04-29 |
2016-10-10 |
Ascendis Pharma Growth Disorders Division A/S |
Pegiliuoto rekombinantinio žmogaus augimo hormono junginiai
|
TW201010692A
(en)
|
2008-06-19 |
2010-03-16 |
Public Univ Corp Nagoya City Univ |
Pharmaceutical composition for treatment or prevention of hbv infection
|
CA2729943A1
(en)
|
2008-07-08 |
2010-01-14 |
Board Of Regents, The University Of Texas System |
Novel inhibitors of proliferation and activation of signal transducer and activator of transcription (stats)
|
PL3225248T3
(pl)
|
2008-07-23 |
2023-11-27 |
Ambrx, Inc. |
Zmodyfikowane polipeptydy bydlęcego G-CSF i ich zastosowania
|
PE20110480A1
(es)
|
2008-09-26 |
2011-07-01 |
Ambrx Inc |
Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales
|
ES2631915T3
(es)
|
2008-09-26 |
2017-09-06 |
Ambrx, Inc. |
Polipéptidos modificados de eritropoyetina animal y sus usos
|
IT1399351B1
(it)
|
2009-06-16 |
2013-04-16 |
Fidia Farmaceutici |
Procedimento per la sintesi di coniugati di glicosamminoglicani (gag) con molecole biologicamente attive, coniugati polimerici e usi relativi
|
EP2459211A1
(en)
|
2009-07-31 |
2012-06-06 |
Medtronic, Inc. |
Continuous subcutaneous administration of interferon- to hepatitis c infected patients
|
BR112012010110A2
(pt)
|
2009-10-30 |
2019-09-24 |
Boehringer Ingelheim Int |
regimes de dosagem para terapia combinada para hcv compreendendo bi201335, interferon alfa e ribavirina
|
CA2784793A1
(en)
|
2009-12-21 |
2011-07-21 |
Ambrx, Inc. |
Modified bovine somatotropin polypeptides and their uses
|
MX2012006980A
(es)
|
2009-12-21 |
2012-07-17 |
Ambrx Inc |
Polipeptidos de somatotropina porcina modificados y sus usos.
|
JP6148013B2
(ja)
|
2010-03-05 |
2017-06-14 |
リグショスピタレト |
補体活性化のキメラ抑制分子
|
JP2013528374A
(ja)
|
2010-05-10 |
2013-07-11 |
パーシード セラピューティクス リミテッド ライアビリティ カンパニー |
Vla4のポリペプチド阻害剤
|
BR112012033022A2
(pt)
|
2010-06-24 |
2016-12-20 |
Genosciense Pharma Sas |
tratamento de vírus de hepatite c relacionado a doenças utilizando hidroxicloroquina ou uma combinação de hidroxicloroquina e um agente antiviral
|
RU2447083C1
(ru)
*
|
2010-07-20 |
2012-04-10 |
Закрытое Акционерное Общество "Биокад" |
НОВЫЙ ФУНКЦИОНАЛЬНО АКТИВНЫЙ ВЫСОКООЧИЩЕННЫЙ СТАБИЛЬНЫЙ КОНЪЮГАТ ИНТЕРФЕРОНА α С ПОЛИЭТИЛЕНГЛИКОЛЕМ, ПРЕДСТАВЛЕННЫЙ ОДНИМ ПОЗИЦИОННЫМ ИЗОМЕРОМ ПЭГ-NαH-ИФН, С УМЕНЬШЕННОЙ ИММУНОГЕННОСТЬЮ, С ПРОЛОНГИРОВАННЫМ БИОЛОГИЧЕСКИМ ДЕЙСТВИЕМ, ПРИГОДНЫЙ ДЛЯ МЕДИЦИНСКОГО ПРИМЕНЕНИЯ, И ИММУНОБИОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ
|
JP2013541937A
(ja)
|
2010-08-05 |
2013-11-21 |
エフ.ホフマン−ラ ロシュ アーゲー |
抗mhc抗体−抗ウイルス性サイトカイン融合タンパク質
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
PT3572091T
(pt)
|
2010-08-17 |
2024-03-01 |
Ambrx Inc |
Polipéptidos de relaxina modificados e as suas utilizações
|
AR083006A1
(es)
|
2010-09-23 |
2013-01-23 |
Lilly Co Eli |
Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
|
WO2012146630A1
(en)
|
2011-04-29 |
2012-11-01 |
F. Hoffmann-La Roche Ag |
N-terminal acylated polypeptides, methods for their production and uses thereof
|
CN102229667A
(zh)
*
|
2011-06-03 |
2011-11-02 |
北京伟嘉人生物技术有限公司 |
一种聚乙二醇修饰的猪α-干扰素及其制备方法和应用
|
JP2014522641A
(ja)
|
2011-07-01 |
2014-09-08 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
リラキシン融合ポリペプチドおよびその使用
|
US20140377218A1
(en)
|
2011-08-03 |
2014-12-25 |
Cytheris |
Hcv immunotherapy
|
JP2015509980A
(ja)
|
2012-03-14 |
2015-04-02 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Hcv−hiv同時感染患者集団のhcv感染症を治療するための併用療法
|
JP2015512900A
(ja)
|
2012-03-28 |
2015-04-30 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
特別な患者の遺伝子亜型分集団のhcv感染症を治療するための併用療法
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
DK2863955T3
(en)
|
2012-06-26 |
2017-01-23 |
Sutro Biopharma Inc |
MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF
|
EP3584255B1
(en)
|
2012-08-31 |
2022-02-16 |
Sutro Biopharma, Inc. |
Modified amino acids comprising an azido group
|
EA022617B1
(ru)
*
|
2013-03-28 |
2016-02-29 |
Илья Александрович МАРКОВ |
Монопегилированный интерферон-альфа разветвленной структуры и фармацевтическая композиция для приготовления лекарственного средства, обладающего активностью интерферона-альфа
|
EA021610B1
(ru)
*
|
2013-03-28 |
2015-07-30 |
Илья Александрович МАРКОВ |
Жидкое противовирусное лекарственное средство
|
EA023323B1
(ru)
*
|
2013-03-28 |
2016-05-31 |
Илья Александрович МАРКОВ |
Разветвленный ацилазидный пегилирующий агент, способ его получения и способ получения пегилированного интерферона
|
ES2865473T3
(es)
|
2013-07-10 |
2021-10-15 |
Sutro Biopharma Inc |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
US9840493B2
(en)
|
2013-10-11 |
2017-12-12 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
EP2907512A1
(en)
|
2014-02-14 |
2015-08-19 |
Commissariat A L'energie Atomique Et Aux Energies Alternatives |
Inhibitors of MMP-12 as antiviral Agents
|
RU2554761C1
(ru)
*
|
2014-05-13 |
2015-06-27 |
Закрытое акционерное общество "Сибирский центр фармакологии и биотехнологии" |
Противоэнтеровирусное и иммуностимулирующее средство
|
EP3412302B1
(en)
|
2014-10-24 |
2021-05-12 |
Bristol-Myers Squibb Company |
Modified fgf-21 polypeptides and uses thereof
|
ES2966888T3
(es)
*
|
2014-11-06 |
2024-04-24 |
Pharmaessentia Corp |
Régimen de dosificación para el interferón pegilado
|
IL251906B2
(en)
|
2014-11-18 |
2024-04-01 |
Ascendis Pharma Endocrinology Div A/S |
Novel polymeric human growth hormone drug matrices
|
PT3220892T
(pt)
|
2014-11-21 |
2021-11-05 |
Ascendis Pharma Endocrinology Div A/S |
Formas de dosagem de hormona do crescimento de longa ação
|
BR112018009009A8
(pt)
|
2015-11-03 |
2019-02-26 |
Hoffmann La Roche |
terapia combinada de um inibidor de formação de capsídeo hbv e um interferon
|
CN106749608B
(zh)
*
|
2015-11-18 |
2021-10-15 |
石药集团中奇制药技术(石家庄)有限公司 |
干扰素α缀合物
|
WO2018087345A1
(en)
|
2016-11-14 |
2018-05-17 |
F. Hoffmann-La Roche Ag |
COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON
|
MX2019008449A
(es)
|
2017-02-08 |
2019-09-09 |
Bristol Myers Squibb Co |
Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos.
|
RU2678332C1
(ru)
|
2017-09-08 |
2019-01-28 |
Общество с ограниченной ответственностью "Саентифик Фьючер Менеджмент" (ООО "СФМ") |
Пегилированный интерферон лямбда, обладающий высокой биодоступностью при пероральном применении, и способ его получения
|
US12049485B2
(en)
|
2018-09-11 |
2024-07-30 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and their uses
|
WO2020082057A1
(en)
|
2018-10-19 |
2020-04-23 |
Ambrx, Inc. |
Interleukin-10 polypeptide conjugates, dimers thereof, and their uses
|
KR20210136014A
(ko)
|
2019-02-12 |
2021-11-16 |
암브룩스, 인코포레이티드 |
항체-tlr 작용제 콘쥬게이트를 함유하는 조성물, 방법 및 이의 용도
|
CN115243726A
(zh)
|
2020-03-11 |
2022-10-25 |
北京泰德制药股份有限公司 |
白介素-2多肽偶联物及其使用方法
|
CA3190606A1
(en)
|
2020-08-20 |
2022-02-24 |
Ambrx, Inc. |
Antibody-tlr agonist conjugates, methods and uses thereof
|
WO2022140783A1
(en)
*
|
2020-12-23 |
2022-06-30 |
Jazz Pharmaceuticals Ireland Ltd. |
Methods of purifying charge-shielded fusion proteins
|
CA3213805A1
(en)
|
2021-04-03 |
2022-10-06 |
Feng Tian |
Anti-her2 antibody-drug conjugates and uses thereof
|