SMT201600090B - Composizioni monovalenti per il legame a cd28 e metodi di utilizzo - Google Patents

Composizioni monovalenti per il legame a cd28 e metodi di utilizzo

Info

Publication number: SMT201600090B
Authority: SM; San Marino
Prior art keywords: monoval; bond; compositions; methods; monoval compositions
Prior art date: 2008-07-18

Application number

SM201600090T

Other languages

English (en)

Inventor

Murray Mckinnon

Steven G Nadler

Suzanne J Suchard

Brendan Classon

Steve Holmes

Olga Ignatovich

Christopher Plummer

Steve Grant

Original Assignee

Bristol Myers Squibb Co

Domantis Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-18

Filing date

2016-03-29

Publication date

2016-04-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41226147&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201600090(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-03-29 Application filed by Bristol Myers Squibb Co, Domantis Ltd filed Critical Bristol Myers Squibb Co

2016-04-29 Publication of SMT201600090B publication Critical patent/SMT201600090B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Mycology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Dermatology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Vascular Medicine (AREA)
Neurology (AREA)
Obesity (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Cardiology (AREA)

SM201600090T 2008-07-18 2016-03-29 Composizioni monovalenti per il legame a cd28 e metodi di utilizzo SMT201600090B (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US8207808P	2008-07-18	2008-07-18
US16212109P	2009-03-20	2009-03-20
PCT/US2009/050985 WO2010009391A1 (en)	2008-07-18	2009-07-17	Compositions monovalent for cd28 binding and methods of use

Publications (1)

Publication Number	Publication Date
SMT201600090B true SMT201600090B (it)	2016-04-29

Family

ID=41226147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM201600090T SMT201600090B (it)	2008-07-18	2016-03-29	Composizioni monovalenti per il legame a cd28 e metodi di utilizzo

Country Status (30)

Country	Link
US (6)	US8168759B2 (it)
EP (2)	EP2321352B1 (it)
JP (3)	JP5675608B2 (it)
KR (2)	KR101660057B1 (it)
CN (2)	CN105936648B (it)
AR (1)	AR072571A1 (it)
AU (1)	AU2009270726B2 (it)
CA (1)	CA2731220C (it)
CL (2)	CL2011000117A1 (it)
CO (1)	CO6341641A2 (it)
CY (1)	CY1121796T1 (it)
DK (2)	DK2321352T3 (it)
EA (1)	EA024585B1 (it)
ES (2)	ES2562629T3 (it)
HK (1)	HK1155178A1 (it)
HR (2)	HRP20160329T1 (it)
HU (2)	HUE045249T2 (it)
IL (2)	IL210413A (it)
LT (1)	LT2700651T (it)
ME (1)	ME02396B (it)
MX (1)	MX2011000501A (it)
NZ (1)	NZ590343A (it)
PE (2)	PE20110385A1 (it)
PL (2)	PL2700651T3 (it)
PT (2)	PT2321352E (it)
RS (2)	RS58904B1 (it)
SI (2)	SI2321352T1 (it)
SM (1)	SMT201600090B (it)
TW (2)	TWI450725B (it)
WO (1)	WO2010009391A1 (it)

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Publication number	Publication date
TWI450725B (zh)	2014-09-01
SI2700651T1 (sl)	2019-08-30
TW201336510A (zh)	2013-09-16
HUE029982T2 (en)	2017-04-28
NZ590343A (en)	2012-10-26
JP5876134B2 (ja)	2016-03-02
US20180142023A1 (en)	2018-05-24
ME02396B (me)	2016-08-31
US9085629B2 (en)	2015-07-21
EA024585B1 (ru)	2016-10-31
PT2321352E (pt)	2016-03-18
US20100028354A1 (en)	2010-02-04
PE20140852A1 (es)	2014-07-14
JP6058833B2 (ja)	2017-01-11
DK2700651T3 (da)	2019-07-22
IL251320A0 (en)	2017-05-29
CN105936648A (zh)	2016-09-14
EA201100239A1 (ru)	2011-10-31
TW201006494A (en)	2010-02-16
ES2730727T3 (es)	2019-11-12
US9908937B2 (en)	2018-03-06
PL2321352T3 (pl)	2016-06-30
EP2321352B1 (en)	2016-01-06
HUE045249T2 (hu)	2019-12-30
HK1155178A1 (zh)	2012-05-11
JP5675608B2 (ja)	2015-02-25
KR101660057B1 (ko)	2016-09-26
PL2700651T3 (pl)	2019-09-30
US20130109846A1 (en)	2013-05-02
HRP20160329T1 (hr)	2016-04-22
CY1121796T1 (el)	2020-07-31
CN105936648B (zh)	2020-06-16
RS58904B1 (sr)	2019-08-30
HRP20190966T1 (hr)	2019-07-26
KR20110041527A (ko)	2011-04-21
MX2011000501A (es)	2011-05-23
IL210413A (en)	2017-04-30
US20120201814A1 (en)	2012-08-09
US12012452B2 (en)	2024-06-18
KR20160113322A (ko)	2016-09-28
PT2700651T (pt)	2019-06-19
RS54675B1 (en)	2016-08-31
DK2321352T3 (en)	2016-04-04
EP2700651B1 (en)	2019-04-10
US10919965B2 (en)	2021-02-16
IL251320B (en)	2019-01-31
US20150299321A1 (en)	2015-10-22
IL210413A0 (en)	2011-03-31
WO2010009391A1 (en)	2010-01-21
EP2321352A1 (en)	2011-05-18
KR101791372B1 (ko)	2017-10-27
US20210047414A1 (en)	2021-02-18
SI2321352T1 (sl)	2016-04-29
JP2016063830A (ja)	2016-04-28
PE20110385A1 (es)	2011-06-22
AU2009270726B2 (en)	2015-07-09
US8454959B2 (en)	2013-06-04
CN102159590A (zh)	2011-08-17
CO6341641A2 (es)	2011-11-21
CA2731220A1 (en)	2010-01-21
CA2731220C (en)	2017-10-10
AU2009270726A1 (en)	2010-01-21
JP2011528551A (ja)	2011-11-24
LT2700651T (lt)	2019-06-25
ES2562629T3 (es)	2016-03-07
US8168759B2 (en)	2012-05-01
CL2012002428A1 (es)	2013-01-11
AR072571A1 (es)	2010-09-08
CL2011000117A1 (es)	2011-06-17
EP2700651A1 (en)	2014-02-26
JP2015120695A (ja)	2015-07-02

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