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SK281802B6 - Steroidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

Steroidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

Info

Publication number
SK281802B6
SK281802B6 SK797-93A SK79793A SK281802B6 SK 281802 B6 SK281802 B6 SK 281802B6 SK 79793 A SK79793 A SK 79793A SK 281802 B6 SK281802 B6 SK 281802B6
Authority
SK
Slovakia
Prior art keywords
dione
butylidenedioxy
ene
difluoro
hydroxy
Prior art date
Application number
SK797-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK79793A3 (en
Inventor
Bengt Axelsson
Ralph Brattsand
Leif Kallstr�M
Arne Thaln
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of SK79793A3 publication Critical patent/SK79793A3/sk
Publication of SK281802B6 publication Critical patent/SK281802B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SK797-93A 1991-02-04 1992-01-29 Steroidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie SK281802B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters
PCT/SE1992/000056 WO1992013873A1 (fr) 1991-02-04 1992-01-29 Nouveaux esters steroidiques

Publications (2)

Publication Number Publication Date
SK79793A3 SK79793A3 (en) 1994-03-09
SK281802B6 true SK281802B6 (sk) 2001-08-06

Family

ID=20381807

Family Applications (1)

Application Number Title Priority Date Filing Date
SK797-93A SK281802B6 (sk) 1991-02-04 1992-01-29 Steroidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (38)

Country Link
US (1) US5614514A (fr)
EP (1) EP0572451B1 (fr)
JP (1) JP2947933B2 (fr)
KR (1) KR100205835B1 (fr)
CN (3) CN1039329C (fr)
AP (1) AP365A (fr)
AT (1) ATE164589T1 (fr)
BG (1) BG61816B1 (fr)
CA (1) CA2100453A1 (fr)
CZ (1) CZ282057B6 (fr)
DE (1) DE69224982T2 (fr)
DK (1) DK0572451T3 (fr)
DZ (1) DZ1554A1 (fr)
EE (1) EE03110B1 (fr)
ES (1) ES2114931T3 (fr)
FI (1) FI933451A0 (fr)
HK (1) HK1004335A1 (fr)
HU (1) HU221168B1 (fr)
IE (1) IE920167A1 (fr)
IL (1) IL100542A (fr)
IS (1) IS1653B (fr)
MA (1) MA22407A1 (fr)
MX (1) MX9200374A (fr)
MY (1) MY111502A (fr)
NO (1) NO304074B1 (fr)
NZ (1) NZ241211A (fr)
PL (1) PL170383B1 (fr)
PT (1) PT100087B (fr)
RO (1) RO111272B1 (fr)
RU (1) RU2112775C1 (fr)
SE (1) SE9100342D0 (fr)
SK (1) SK281802B6 (fr)
TN (1) TNSN92008A1 (fr)
TW (1) TW287166B (fr)
UA (1) UA43825C2 (fr)
WO (1) WO1992013873A1 (fr)
YU (1) YU48893B (fr)
ZA (1) ZA92234B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
ES2137353T3 (es) * 1993-01-08 1999-12-16 Astra Ab Nuevos derivados esteroides especificos del colon o del ileon.
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
ES2347027T3 (es) 1998-05-22 2010-10-22 The Board Of Trustees Of The Leland Stanford Junior University Moleculas bifuncionales y terapias basadas en las mismas.
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
PT1180017E (pt) 1999-05-27 2010-05-28 Euro Celtique Sa Preparações com povidona-iodo para o tratamento de feridas
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
AU2003217535A1 (en) 2002-02-20 2003-09-09 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids
US20050009798A1 (en) 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
AU2003264917A1 (en) 2002-07-08 2004-01-23 Pliva - Istrazivacki Institut D.O.O. Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
US7091187B2 (en) 2002-07-08 2006-08-15 Pliva-Istrazivacki Institut D.O.O. Compounds, compositions and methods for treatment of inflammatory diseases and conditions
EP1562627A4 (fr) * 2002-08-23 2006-11-02 Mclean Hospital Corp Conjugues de corticosteroides et utilisations de ceux-ci
US20040235811A1 (en) * 2002-10-08 2004-11-25 Sepracor Inc. Fatty acid modified forms of glucocorticoids
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
AU2003257154A1 (en) * 2003-08-05 2005-03-07 Sepracor Inc. AMINO ACID AND PEPTIDE-MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH ss2 ADRENERGIC AGONISTS
ES2337915T3 (es) 2004-10-27 2010-04-30 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugados con adtividad antiinflamatoria.
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
EP1945240B1 (fr) 2005-09-16 2016-12-28 Raptor Pharmaceutical Inc Compositions de proteines rap specifiques des proteines contenant du cr, et leurs utilisations
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US8737506B1 (en) 2010-12-29 2014-05-27 Sprint Communications Company L.P. Determination of transmit diversity transmission delays
US8437713B1 (en) 2011-02-16 2013-05-07 Sprint Communications Company L.P. Wireless transmit diversity control by location of a wireless communication device
US8565686B2 (en) 2011-06-30 2013-10-22 Sprint Communications Company L.P. Power status multipath search window sizing for wireless communications
US10058616B2 (en) 2012-02-10 2018-08-28 Tlc Biopharmaceuticals, Inc. Pharmaceutical compositions to reduce complications of ocular steroid
JP5965187B2 (ja) * 2012-03-30 2016-08-03 小林製薬株式会社 油性軟膏剤
CN109985048B (zh) * 2017-12-29 2021-06-29 广州市赛普特医药科技股份有限公司 2β,3α,5α-三羟基雄甾-6-酮用于炎症反应的治疗

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3197469A (en) * 1958-08-06 1965-07-27 Pharmaceutical Res Products In 16, 17-acetals and ketals of 6-halo-16, 17-dihydroxy steroids of the pregnane seriesand intermediates therefor
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378109B (fr) * 1972-05-19 1975-08-18 Bofors Ab
US3796701A (en) * 1973-02-26 1974-03-12 Squibb & Sons Inc 5alpha,9-oxazino steroids and 9-carboxamido steroids
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4304727A (en) * 1980-12-05 1981-12-08 The Upjohn Company 9α-Debromination
JPS58176485A (ja) * 1982-04-08 1983-10-15 Nippon Denso Co Ltd 可変容量圧縮機
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6067496A (ja) * 1983-09-26 1985-04-17 Ota Seiyaku Kk フルオシノロン１６，１７−アセトニド２１−ブチレ−トおよびその製造法
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters

Also Published As

Publication number Publication date
UA43825C2 (uk) 2002-01-15
NZ241211A (en) 1993-08-26
NO932762L (no) 1993-08-02
NO932762D0 (no) 1993-08-02
EP0572451A1 (fr) 1993-12-08
PT100087A (pt) 1993-05-31
YU6492A (sh) 1994-12-28
IL100542A0 (en) 1992-09-06
AU661472B2 (en) 1995-07-27
BG61816B1 (bg) 1998-06-30
BG98011A (bg) 1994-04-29
MY111502A (en) 2000-07-31
SK79793A3 (en) 1994-03-09
AP9200354A0 (en) 1992-01-31
PT100087B (pt) 1999-09-30
DK0572451T3 (da) 1998-10-19
MX9200374A (es) 1992-08-01
CN1039329C (zh) 1998-07-29
KR100205835B1 (ko) 1999-07-01
IE920167A1 (en) 1992-08-12
FI933451A (fi) 1993-08-03
NO304074B1 (no) 1998-10-19
YU48893B (sh) 2002-10-18
JPH06505233A (ja) 1994-06-16
TNSN92008A1 (fr) 1993-06-08
IS1653B (is) 1997-06-20
AU1235892A (en) 1992-09-07
MA22407A1 (fr) 1992-10-01
AP365A (en) 1994-10-21
HU9302243D0 (en) 1993-10-28
DE69224982T2 (de) 1998-07-30
CZ282057B6 (cs) 1997-05-14
EE03110B1 (et) 1998-08-17
SE9100342D0 (sv) 1991-02-04
IL100542A (en) 1997-02-18
CA2100453A1 (fr) 1992-08-05
RU2112775C1 (ru) 1998-06-10
CN1076607C (zh) 2001-12-26
HU221168B1 (en) 2002-08-28
TW287166B (fr) 1996-10-01
RO111272B1 (ro) 1996-08-30
IS3809A (is) 1992-08-05
DZ1554A1 (fr) 2002-02-17
CN1155418A (zh) 1997-07-30
CN1158726A (zh) 1997-09-10
HUT64972A (en) 1994-03-28
ATE164589T1 (de) 1998-04-15
FI933451A0 (fi) 1993-08-03
JP2947933B2 (ja) 1999-09-13
ZA92234B (en) 1992-10-28
DE69224982D1 (de) 1998-05-07
EP0572451B1 (fr) 1998-04-01
CN1064078A (zh) 1992-09-02
PL170383B1 (pl) 1996-12-31
WO1992013873A1 (fr) 1992-08-20
US5614514A (en) 1997-03-25
HK1004335A1 (en) 1998-11-20
CN1076606C (zh) 2001-12-26
ES2114931T3 (es) 1998-06-16
CZ149593A3 (en) 1994-03-16

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