SK280777B6 - 5-[4-[2-(n-metyl-n-(2-pyridyl)amino)etoxy]benzyl]- - Google Patents

5-[4-[2-(n-metyl-n-(2-pyridyl)amino)etoxy]benzyl]- Download PDF

Info

Publication number: SK280777B6
Authority: SK; Slovakia
Prior art keywords: pyridyl; ethoxy; benzyl; amino; methyl
Prior art date: 1992-09-05

Application number

SK277-95A

Other languages

English (en)

Slovak (sk)

Other versions

SK27795A3 (en

Inventor

Colin Ripley Pool

Robin Sherwood Roman

Malcolm David Brighwell

Alan William Tremper

Original Assignee

Smithkline Beecham P. L. C.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-05

Filing date

1993-09-01

Publication date

2000-07-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10721461&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK280777(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-09-01 Application filed by Smithkline Beecham P. L. C. filed Critical Smithkline Beecham P. L. C.

1995-08-09 Publication of SK27795A3 publication Critical patent/SK27795A3/sk

2000-07-11 Publication of SK280777B6 publication Critical patent/SK280777B6/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Nutrition Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SK277-95A 1992-09-05 1993-09-01 5-[4-[2-(n-metyl-n-(2-pyridyl)amino)etoxy]benzyl]- SK280777B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929218830A GB9218830D0 (en)	1992-09-05	1992-09-05	Novel compounds
PCT/GB1993/001853 WO1994005659A1 (en)	1992-09-05	1993-09-01	Substituted thiazolidinedione derivatives

Publications (2)

Publication Number	Publication Date
SK27795A3 SK27795A3 (en)	1995-08-09
SK280777B6 true SK280777B6 (sk)	2000-07-11

Family

ID=10721461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK277-95A SK280777B6 (sk)	1992-09-05	1993-09-01	5-[4-[2-(n-metyl-n-(2-pyridyl)amino)etoxy]benzyl]-

Country Status (37)

Country	Link
US (1)	US5910592A (es)
EP (2)	EP0658161B1 (es)
JP (5)	JP2828777B2 (es)
KR (3)	KR20030097596A (es)
CN (4)	CN1040323C (es)
AP (1)	AP513A (es)
AT (1)	ATE182147T1 (es)
AU (1)	AU674880B2 (es)
BR (1)	BR1100916A (es)
CA (2)	CA2143849C (es)
CY (1)	CY2138B1 (es)
CZ (2)	CZ287473B6 (es)
DE (2)	DE69325658T2 (es)
DK (1)	DK0658161T3 (es)
ES (1)	ES2133410T3 (es)
FI (2)	FI982413A0 (es)
GB (1)	GB9218830D0 (es)
GR (1)	GR3030794T3 (es)
HU (2)	HU224212B1 (es)
IL (1)	IL106904A (es)
LU (1)	LU90712I2 (es)
MA (1)	MA22970A1 (es)
MX (1)	MX9305397A (es)
MY (1)	MY111190A (es)
NL (1)	NL300035I2 (es)
NO (4)	NO303016B1 (es)
NZ (1)	NZ255505A (es)
PL (1)	PL173725B1 (es)
RU (3)	RU2128179C1 (es)
SA (1)	SA93140245B1 (es)
SG (2)	SG83747A1 (es)
SI (1)	SI9300452B (es)
SK (1)	SK280777B6 (es)
TW (1)	TW385309B (es)
UA (1)	UA41901C2 (es)
WO (1)	WO1994005659A1 (es)
ZA (1)	ZA936509B (es)

Families Citing this family (110)

* Cited by examiner, † Cited by third party
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GB9308487D0 (en) *	1993-04-23	1993-06-09	Smithkline Beecham Plc	Novel compounds
US5919782A (en) *	1996-05-06	1999-07-06	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
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US5801173A (en) *	1996-05-06	1998-09-01	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
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KR100579765B1 (ko)	1996-07-01	2006-12-28	닥터 레디스 레보러터리즈 리미티드	신규헤테로고리형화합물의제조방법,이를함유하는약제조성물및당뇨병및이와관련된질병의치료에있어서그의용도
US5885997A (en) *	1996-07-01	1999-03-23	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) *	1996-07-01	2000-09-05	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en)	1996-07-01	2002-04-16	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) *	1996-07-01	2006-09-05	Dr. Reddy's Laboratories, Limited	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
PL331148A1 (en) *	1996-07-12	1999-06-21	Smithkline Beecham Plc	Novel method of treating the leptin immunity
GB9711683D0 (en) *	1997-06-05	1997-08-06	Smithkline Beecham Plc	Composition
EA003025B1 (ru) *	1997-06-18	2002-12-26	Смитклайн Бичам Плс	Лечение диабета тиазолидиндионом и сульфонилмочевиной
SI0996444T1 (sl) *	1997-06-18	2007-08-31	Smithkline Beecham Plc	Zdravljenje diabetesa s tiazolidindionom in metforminom
GB9715306D0 (en) *	1997-07-18	1997-09-24	Smithkline Beecham Plc	Novel method of treatment
US20010031776A1 (en) *	1997-10-13	2001-10-18	Smithkline Beecham P.L.C.	Use of thiazolidinediones for the treatment of hyperglycaemia
GB9721692D0 (en) *	1997-10-13	1997-12-10	Smithkline Beecham Plc	Novel treatment
GB9721693D0 (en) *	1997-10-13	1997-12-10	Smithkline Beecham Plc	Novel treatment
US20020006939A1 (en) *	1997-10-13	2002-01-17	Smithkline Beecham P.L.C.	Use of thiazolidinediones for the treatment of hyperglycaemia
GB9723295D0 (en) *	1997-11-04	1998-01-07	Smithkline Beecham Plc	Novel process
US7091359B2 (en)	1997-11-04	2006-08-15	Smithkline Beecham Plc	Process for the preparation of thiazolidinedione derivatives
AU774613B2 (en) *	1997-12-16	2004-07-01	Smithkline Beecham Plc	Hydrate of 5-(4-(2- (N-methyl-N- (2-pyridil)amino) ethoxy)benzyl) thiazolidine-2,4-dione maleic acid salt
US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
US20020137940A1 (en)	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726568D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
GB9726563D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
GB9726566D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
AU770817B2 (en) *	1997-12-16	2004-03-04	Smithkline Beecham Plc	5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl) thiazolidine-2,dione,maleic acid salt, hydrate as pharmaceutical
US7045519B2 (en)	1998-06-19	2006-05-16	Chiron Corporation	Inhibitors of glycogen synthase kinase 3
MA26662A1 (fr) *	1998-07-21	2004-12-20	Smithkline Beecham Plc	Derives de thiazolidinedione, compositions pharmaceutiques les contenant et leur utilisation
HUP0103199A3 (en) *	1998-07-21	2002-08-28	Smithkline Beecham Lab	Use of glucose uptake enhancer for reducing apoptosis
US6613785B2 (en)	1998-07-21	2003-09-02	Smithkline Beecham Plc	Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
GB9824893D0 (en) *	1998-11-12	1999-01-06	Smithkline Beckman Corp	Novel method of treatment
US20040102486A1 (en) *	1998-11-12	2004-05-27	Smithkline Beecham Corporation	Novel method of treatment
AR023700A1 (es) *	1998-11-12	2002-09-04	Smithkline Beecham Plc	Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
US20030153607A1 (en) *	1998-11-12	2003-08-14	Smithkline Beecham P.L.C.	Novel composition and use
DE69939485D1 (de) *	1998-11-12	2008-10-16	Smithkline Beecham Plc	Arzneimittel zur gesteuerten freisetzung eines insulin sensibilisators und metformin
GB9909041D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
GB9909075D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
CZ20013801A3 (cs) *	1999-04-23	2002-07-17	Smithkline Beecham Plc	Nový léčivý přípravek
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
OA11871A (en) *	1999-04-23	2006-03-27	Smithkline Beecham Plc	Novel pharmaceutical.
DK1173435T3 (da) *	1999-04-23	2003-11-24	Smithkline Beecham Cork Ltd	Polymorf af 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxyl]benzyl]thiazolidin-2,4-dion, maleinsyresalt
MXPA02001716A (es) *	1999-08-17	2002-08-06	Smithkline Beecham Plc	Composiciones farmaceuticas que contienen derivados de tiazolidinediona y procedimiento para su preparacion.
AR030920A1 (es) *	1999-11-16	2003-09-03	Smithkline Beecham Plc	Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones
GB0006133D0 (en) *	2000-03-14	2000-05-03	Smithkline Beecham Plc	Novel pharmaceutical
GB0014005D0 (en) *	2000-06-08	2000-08-02	Smithkline Beecham Plc	Novel pharmaceutical
GB0014006D0 (en) *	2000-06-08	2000-08-02	Smithkline Beecham Plc	Novel pharmaceutical
YU1203A (sh) *	2000-06-16	2006-05-25	Smithkline Beecham P.L.C.	Lečenje i prevencija stanja vezanih za insulinsku rezistenciju srca
GB0014969D0 (en)	2000-06-19	2000-08-09	Smithkline Beecham Plc	Novel method of treatment
GB0019223D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0019228D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0019224D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
AU2005229688B2 (en) *	2000-08-04	2008-04-03	Smithkline Beecham P.L.C.	Tartrate salts of thiazolidinedione derivative
AU2005229687B2 (en) *	2000-08-04	2008-03-13	Smithkline Beecham P.L.C.	Tartrate salts of thiazolidinedione derivative
GB0019226D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0021784D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021785D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel Pharmaceutical
GB0021865D0 (en) *	2000-09-06	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021978D0 (en) *	2000-09-07	2000-10-25	Smithkline Beecham Plc	Novel pharmaceutical
US7241895B2 (en)	2000-09-26	2007-07-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
KR20030082541A (ko) *	2000-09-26	2003-10-22	닥터 레디스 레보러터리즈 리미티드	5-[4-[2-[엔-메틸-엔-(2-피리딜)아미노]에톡시]벤질]티아졸리딘 4-디온 말레이트의 신규의 다형상 및 그제조방법
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DE60122580T2 (de) *	2000-12-22	2007-08-30	Smithkline Beecham P.L.C., Brentford	5-4'-2'-(n-methyl-n-(2-pyridyl)amino) ethoxy!benzyl!thiazolidin-2,4-dion mesylatsalz
WO2002051823A1 (en)	2000-12-26	2002-07-04	Torrent Pharmaceuticals Ltd	Process for the preparation of rosiglitazone maleate
GB0127805D0 (en)	2001-11-20	2002-01-09	Smithkline Beecham Plc	Pharmaceutical composition
DE60217168T2 (de) *	2001-11-21	2007-10-04	Smithkline Beecham Plc, Brentford	5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dion-benzolsulfonat; prozess zu seiner herstellung; polymorphe i, ii und iii davon; und seine verwendung als pharmazeutischer wirkstoff
JP2005515987A (ja) *	2001-11-21	2005-06-02	スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー	ロジグリタゾンエディシレート抗糖尿病剤としてのその使用
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1992
- 1992-09-05 GB GB929218830A patent/GB9218830D0/en active Pending
1993
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1995
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1997
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1998
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Publication number	Publication date
JP2008208142A (ja)	2008-09-11
SG48302A1 (en)	1998-04-17
CY2138B1 (en)	2002-06-21
HUT72639A (en)	1996-05-28
CN1101911A (zh)	1995-04-26
FI951004L (fi)	1995-03-03
PL307812A1 (en)	1995-06-26
KR20080081099A (ko)	2008-09-05
DE10199002I2 (de)	2001-12-13
KR20030097596A (ko)	2003-12-31
UA41901C2 (uk)	2001-10-15
DK0658161T3 (da)	1999-11-29
HU9500659D0 (en)	1995-04-28
FI951004A0 (fi)	1995-03-03
AU674880B2 (en)	1997-01-16
ATE182147T1 (de)	1999-07-15
EP0960883A1 (en)	1999-12-01
RU98117673A (ru)	2000-07-20
TW385309B (en)	2000-03-21
US5910592A (en)	1999-06-08
CN1051312C (zh)	2000-04-12
DE69325658T2 (de)	1999-12-30
CZ56595A3 (en)	1995-11-15
SK27795A3 (en)	1995-08-09
SI9300452B (sl)	2003-02-28
RU2128179C1 (ru)	1999-03-27
CN1040323C (zh)	1998-10-21
JP2004359676A (ja)	2004-12-24
NO303016B1 (no)	1998-05-18
SG83747A1 (en)	2001-10-16
NO2001005I2 (no)	2004-06-01
EP0658161B1 (en)	1999-07-14
GB9218830D0 (en)	1992-10-21
PL173725B1 (pl)	1998-04-30
NO950852L (no)	1995-03-03
KR100371297B1 (ko)	2003-05-09
KR950702982A (ko)	1995-08-23
AU4973093A (en)	1994-03-29
SA93140245B1 (ar)	2005-10-15
MX9305397A (es)	1995-01-31
NL300035I1 (nl)	2001-03-01
NZ255505A (en)	1997-08-22
RU95108329A (ru)	1996-12-20
RU98117628A (ru)	2000-08-20
HU0500355D0 (en)	2005-05-30
JPH08501095A (ja)	1996-02-06
AP513A (en)	1996-07-30
SI9300452A (en)	1994-06-30
FI982413A7 (fi)	1998-11-06
CA2143849C (en)	2000-04-25
NO305802B1 (no)	1999-07-26
FI106263B (fi)	2000-12-29
CA2143849A1 (en)	1994-03-17
CN1066939C (zh)	2001-06-13
AP9300562A0 (en)	1993-10-31
FI982413L (fi)	1998-11-06
NO950852D0 (no)	1995-03-03
JPH11147885A (ja)	1999-06-02
NO974646L (no)	1995-03-03
HK1012363A1 (en)	1999-07-30
IL106904A (en)	1997-09-30
NO974646D0 (no)	1997-10-08
CN1183276A (zh)	1998-06-03
DE69325658D1 (de)	1999-08-19
NL300035I2 (nl)	2001-07-02
BR1100916A (pt)	2000-07-04
CN1063942C (zh)	2001-04-04
JP2828777B2 (ja)	1998-11-25
ZA936509B (en)	1994-06-16
FI982413A0 (fi)	1998-11-06
MY111190A (en)	1999-09-30
CA2273147A1 (en)	1994-03-17
ES2133410T3 (es)	1999-09-16
IL106904A0 (en)	1993-12-28
JP2002047288A (ja)	2002-02-12
GR3030794T3 (en)	1999-11-30
CZ287473B6 (en)	2000-12-13
NO2001006I1 (no)	2001-04-30
EP0658161A1 (en)	1995-06-21
CN1183413A (zh)	1998-06-03
CN1183275A (zh)	1998-06-03
LU90712I2 (fr)	2001-03-12
WO1994005659A1 (en)	1994-03-17
HU224212B1 (hu)	2005-06-28
CZ290591B6 (cs)	2002-08-14
MA22970A1 (fr)	1994-04-01

Publication	Publication Date	Title
SK280777B6 (sk)	2000-07-11	5-[4-[2-(n-metyl-n-(2-pyridyl)amino)etoxy]benzyl]-
US5741803A (en)	1998-04-21	Substituted thiazolidinedionle derivatives
US5661168A (en)	1997-08-26	Hypoglycemic agents
JPH10194970A (ja)	1998-07-28	置換チアゾリジンジオン誘導体を含む抗高脂血剤
SK286399B6 (sk)	2008-09-05	V podstate nehydratovaná a nehygroskopická alebo iba mierne hygroskopická hydrochloridová soľ 5-[4-[2-(N-metyl-N-(2- pyridyl)amino)etoxy]benzyl]tiazolidín-2,4-diónu, spôsob jej prípravy, farmaceutický prostriedok s jej obsahom a jej použitie
IE903074A1 (en)	1991-02-27	Novel compounds
DE60020246T2 (de)	2006-01-19	Substituierte benzylthiazolidin-2,4-dion derivate
US5063240A (en)	1991-11-05	Novel compounds
Buckle et al.	1996	Non thiazolidinedione antihyperglycaemic agents. 2: α-Carbon substituted β-phenylpropanoic acids1
AU650465B2 (en)	1994-06-23	Bisheterocyclic compound
JPS63310872A (ja)	1988-12-19	ドーパミン−β−ヒドロキシラーゼ抑制剤
Kees et al.	1992	Perfluorocarbon-based antidiabetic agents
USRE39384E1 (en)	2006-11-07	Substituted thiazolidinedione derivatives
HK1012363B (en)	2000-05-05	Substituted thiazolidinedione derivatives
HK1029104A (en)	2001-03-23	Substituted thiazolidinedione derivatives
JPS58188881A (ja)	1983-11-04	Ｎ−置換イミダゾ−ル誘導体、この化合物の製法及びこれを含有する医薬
SK391691A3 (sk)	2000-12-11	Tiazolidindiónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
JPH0469385A (ja)	1992-03-04	新規イミダゾリン誘導体

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