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SK287095B6 - Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom - Google Patents

Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom Download PDF

Info

Publication number
SK287095B6
SK287095B6 SK758-2002A SK7582002A SK287095B6 SK 287095 B6 SK287095 B6 SK 287095B6 SK 7582002 A SK7582002 A SK 7582002A SK 287095 B6 SK287095 B6 SK 287095B6
Authority
SK
Slovakia
Prior art keywords
methyl
alkyl
methoxy
product
compounds
Prior art date
Application number
SK758-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK7582002A3 (en
Inventor
Dirk Leysen
Der Louw Jaap Van
Bursi Roberta Buma
Gooyer Marcel Evert De
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of SK7582002A3 publication Critical patent/SK7582002A3/sk
Publication of SK287095B6 publication Critical patent/SK287095B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
SK758-2002A 1999-12-02 2000-11-29 Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom SK287095B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99204080 1999-12-02
PCT/EP2000/012009 WO2001040255A2 (fr) 1999-12-02 2000-11-29 Nouveaux androgènes

Publications (2)

Publication Number Publication Date
SK7582002A3 SK7582002A3 (en) 2002-09-10
SK287095B6 true SK287095B6 (sk) 2009-12-07

Family

ID=8240955

Family Applications (1)

Application Number Title Priority Date Filing Date
SK758-2002A SK287095B6 (sk) 1999-12-02 2000-11-29 Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom

Country Status (27)

Country Link
US (1) US6706700B2 (fr)
EP (1) EP1237904B1 (fr)
JP (1) JP2003515543A (fr)
CN (1) CN1166680C (fr)
AR (1) AR026655A1 (fr)
AT (1) ATE317396T1 (fr)
AU (1) AU778017B2 (fr)
CA (1) CA2390226A1 (fr)
CO (1) CO5251441A1 (fr)
CY (1) CY1106086T1 (fr)
CZ (1) CZ301376B6 (fr)
DE (1) DE60025958T2 (fr)
DK (1) DK1237904T3 (fr)
ES (1) ES2258037T3 (fr)
HK (1) HK1047596B (fr)
HU (1) HUP0203611A3 (fr)
IL (1) IL149424A (fr)
MX (1) MXPA02004939A (fr)
NO (1) NO322422B1 (fr)
NZ (1) NZ518753A (fr)
PE (1) PE20011033A1 (fr)
PL (1) PL202999B1 (fr)
RU (1) RU2242479C2 (fr)
SK (1) SK287095B6 (fr)
TW (1) TWI275593B (fr)
WO (1) WO2001040255A2 (fr)
ZA (1) ZA200203536B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2204613T3 (es) * 1999-04-06 2004-05-01 Akzo Nobel N.V. Androgenos 7-alfa alquilo oralmente activos.
EP1470151B1 (fr) * 2002-01-21 2009-12-30 N.V. Organon Procede de preparation de 7-alpha-methylsteroides
US20080293683A1 (en) * 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy
EP2383279A1 (fr) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Procédé de préparation d'estetrol
WO2013050553A1 (fr) * 2011-10-07 2013-04-11 Estetra S.A. Procédé de production d'estétrol
JP6866561B2 (ja) 2015-06-18 2021-04-28 エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ エステトロールを含有する口腔内崩壊錠
SI3701944T1 (sl) 2015-06-18 2022-04-29 Estetra Srl Orodisperzibilna odmerna enota, ki vsebuje estetrolno komponento
CR20180042A (es) 2015-06-18 2018-05-03 Mithra Pharmaceuticals S A Unidad de dosificación orodispersable que contiene un componente estetrol.
SI3310346T1 (sl) 2015-06-18 2021-07-30 Estetra Sprl Orodisperzibilna tableta, ki vsebuje estetrol
KR102712911B1 (ko) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
CN111621141B (zh) * 2020-06-12 2022-04-08 广西大学 一种缓释型二氧化氯-水性聚氨酯抗菌膜及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) * 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
IE60780B1 (en) 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE19537626A1 (de) 1995-10-10 1997-04-17 Jenapharm Gmbh Steroide mit einer 14, 15-Methylengruppe
DE19827522A1 (de) * 1998-06-22 1999-12-23 Jenapharm Gmbh 14,15-Cyclopropanosteroide der 19-Nor-Androstanreihe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
WO2000053619A1 (fr) * 1999-03-08 2000-09-14 Akzo Nobel N.V. Derives de 14.beta., alpha-hydroxymethylandrostane intervenant comme androgenes

Also Published As

Publication number Publication date
ATE317396T1 (de) 2006-02-15
PE20011033A1 (es) 2001-10-11
CO5251441A1 (es) 2003-02-28
AU778017B2 (en) 2004-11-11
CN1166680C (zh) 2004-09-15
EP1237904B1 (fr) 2006-02-08
ZA200203536B (en) 2003-08-04
HK1047596A1 (en) 2003-02-28
HK1047596B (zh) 2006-04-21
MXPA02004939A (es) 2003-05-23
SK7582002A3 (en) 2002-09-10
CZ301376B6 (cs) 2010-02-03
TWI275593B (en) 2007-03-11
DK1237904T3 (da) 2006-06-06
AR026655A1 (es) 2003-02-19
IL149424A0 (en) 2002-11-10
US20030100543A1 (en) 2003-05-29
CY1106086T1 (el) 2011-06-08
CZ20021894A3 (cs) 2002-08-14
WO2001040255A3 (fr) 2001-11-15
DE60025958T2 (de) 2006-07-27
NO20022564L (no) 2002-05-30
JP2003515543A (ja) 2003-05-07
IL149424A (en) 2007-05-15
PL202999B1 (pl) 2009-08-31
HUP0203611A2 (hu) 2003-03-28
CN1402735A (zh) 2003-03-12
RU2242479C2 (ru) 2004-12-20
US6706700B2 (en) 2004-03-16
DE60025958D1 (de) 2006-04-20
HUP0203611A3 (en) 2004-07-28
PL355689A1 (en) 2004-05-17
CA2390226A1 (fr) 2001-06-07
NO20022564D0 (no) 2002-05-30
NO322422B1 (no) 2006-10-02
ES2258037T3 (es) 2006-08-16
AU2838301A (en) 2001-06-12
EP1237904A2 (fr) 2002-09-11
NZ518753A (en) 2004-05-28
WO2001040255A2 (fr) 2001-06-07

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US6706700B2 (en) 14β,15β-methylene-17α-hydroxymethyl-androgens
US6881728B1 (en) 14-β, 17-α-hydroxymethylandrostane derivatives as androgens
KR100730010B1 (ko) 신규 안드로겐
US20040059140A1 (en) 14(15)-unsaturated 15- and/or 16-substituted androgens with mixed androgen-progrestational profile
EP1343806B1 (fr) Methylene steroides comme nouveaux androgenes
AU2002224923A1 (en) Methylene steroids as novel androgens

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20101129