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SK284987B6 - Substituované aza- a diazabicykloheptánové a -cyklooktánové zlúčeniny, farmaceutická kompozícia s ich obsahom a ich použitie - Google Patents

Substituované aza- a diazabicykloheptánové a -cyklooktánové zlúčeniny, farmaceutická kompozícia s ich obsahom a ich použitie Download PDF

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Publication number
SK284987B6
SK284987B6 SK941-98A SK94198A SK284987B6 SK 284987 B6 SK284987 B6 SK 284987B6 SK 94198 A SK94198 A SK 94198A SK 284987 B6 SK284987 B6 SK 284987B6
Authority
SK
Slovakia
Prior art keywords
alkyl
chj
halogen
compound according
substituted
Prior art date
Application number
SK941-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK94198A3 (en
Inventor
Hans-J�Rg Treiber
Stefan Blank
Dorothea Starck
Liliane Unger
Hans-J�Rgen Teschendorf
Karsten Wicke
Original Assignee
Abbott Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co. Kg filed Critical Abbott Gmbh & Co. Kg
Publication of SK94198A3 publication Critical patent/SK94198A3/sk
Publication of SK284987B6 publication Critical patent/SK284987B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
SK941-98A 1996-01-12 1997-01-10 Substituované aza- a diazabicykloheptánové a -cyklooktánové zlúčeniny, farmaceutická kompozícia s ich obsahom a ich použitie SK284987B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19600934A DE19600934A1 (de) 1996-01-12 1996-01-12 Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung
PCT/EP1997/000106 WO1997025324A1 (de) 1996-01-12 1997-01-10 Substituierte aza- und diazacycloheptan- und -cyclooctanverbindungen und deren verwendung

Publications (2)

Publication Number Publication Date
SK94198A3 SK94198A3 (en) 1999-03-12
SK284987B6 true SK284987B6 (sk) 2006-04-06

Family

ID=7782613

Family Applications (1)

Application Number Title Priority Date Filing Date
SK941-98A SK284987B6 (sk) 1996-01-12 1997-01-10 Substituované aza- a diazabicykloheptánové a -cyklooktánové zlúčeniny, farmaceutická kompozícia s ich obsahom a ich použitie

Country Status (26)

Country Link
US (2) US6214822B1 (cs)
EP (1) EP0877744B1 (cs)
JP (1) JP4349657B2 (cs)
KR (1) KR100441073B1 (cs)
CN (2) CN1075070C (cs)
AR (1) AR005868A1 (cs)
AT (1) ATE273301T1 (cs)
AU (1) AU717726B2 (cs)
BG (1) BG64098B1 (cs)
CA (1) CA2241787C (cs)
CO (1) CO4790173A1 (cs)
CZ (1) CZ297981B6 (cs)
DE (2) DE19600934A1 (cs)
ES (1) ES2225947T3 (cs)
HR (1) HRP970021A2 (cs)
HU (1) HU228457B1 (cs)
IL (1) IL125076A (cs)
MX (1) MX9805499A (cs)
NO (1) NO316753B1 (cs)
NZ (1) NZ326332A (cs)
PL (1) PL327692A1 (cs)
SK (1) SK284987B6 (cs)
TR (1) TR199801302T2 (cs)
TW (1) TW475929B (cs)
WO (1) WO1997025324A1 (cs)
ZA (1) ZA97209B (cs)

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DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
SK4782001A3 (en) 1998-10-08 2001-11-06 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
AR022230A1 (es) * 1999-01-12 2002-09-04 Abbott Gmbh & Co Kg Compuestos de triazol, composicion farmaceutica que los comprende y uso de los mismos para preparar dicha composicion
DE19922443A1 (de) * 1999-05-07 2000-11-09 Basf Ag Verwendung von Dopamin-D3-Rezeptorliganden zur Herstellung von Arzneimittel für die Behandlung von Nierenfunktionsstörungen
US7037916B2 (en) 1999-07-15 2006-05-02 Pharmacopeia Drug Discovery, Inc. Pyrimidine derivatives as IL-8 receptor antagonists
AU2001250404A1 (en) * 2000-03-27 2001-10-08 Basf Aktiengesellschaft Use of dopamine-d3 receptor ligands for the treatment of diseases of the central nervous system
DK1362039T3 (da) 2001-02-16 2006-05-08 Aventis Pharma Inc Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin D3-receptorligander
DE10109866A1 (de) * 2001-03-01 2002-09-05 Abbott Gmbh & Co Kg Triazolverbindungen und deren Verwendung zur Prophylaxe und Therapie neurodegenerativer Erkrankungen, Hirntrauma und zerebraler Ischämie
DE10131543A1 (de) * 2001-06-29 2003-01-16 Abbott Lab Pyrimidinoxyalkylpiperazine und ihre therapeutische Verwendung
US20050154039A1 (en) * 2001-11-28 2005-07-14 Marie-Odile Glacera Contour 5-Sulphanyl-4h-1,2,4-triazole derivatives and their use as medicine
ES2290436T3 (es) * 2002-03-15 2008-02-16 Ciba Specialty Chemicals Holding Inc. Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies.
DE10304870A1 (de) 2003-02-06 2004-08-19 Abbott Gmbh & Co. Kg Triazolverbindungen und ihre therapeutische Verwendung
TW200507841A (en) * 2003-03-27 2005-03-01 Glaxo Group Ltd Antibacterial agents
DE10358004A1 (de) * 2003-12-11 2005-07-14 Abbott Gmbh & Co. Kg Ketolactam-Verbindungen und ihre Verwendung
DE102004027358A1 (de) 2004-06-04 2005-12-29 Abbott Gmbh & Co. Kg Pyrimidinverbindungen und ihre Verwendung
FR2877005A1 (fr) * 2004-10-22 2006-04-28 Bioprojet Soc Civ Ile Nouveaux derives d'arylpiperazine
US7511035B2 (en) * 2005-01-25 2009-03-31 Glaxo Group Limited Antibacterial agents
JP2007106746A (ja) * 2005-09-13 2007-04-26 Tosoh Corp 新規アリールホモピペラジン類、またはその塩と製造方法
US7935706B2 (en) * 2006-02-23 2011-05-03 Shionogi & Co., Ltd. Nitrogen-containing heterocycle derivatives substituted with cyclic group
EP2004166A2 (en) * 2006-03-31 2008-12-24 La Jolla Pharmaceutical Company Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment and prevention of diseases
EP1882688A1 (en) * 2006-07-25 2008-01-30 EPFL Ecole Polytechnique Fédérale de Lausanne Labelling of fusion proteins with synthetic probes
JP4840440B2 (ja) * 2008-12-24 2011-12-21 ソニー株式会社 画像処理装置およびその方法、並びにプログラム
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
KR20120131161A (ko) * 2010-01-25 2012-12-04 씨에이치디아이 파운데이션, 인코포레이티드 특정 키뉴레닌-3-모노옥시게나제 억제제, 그의 제약 조성물 및 사용 방법
WO2012003418A2 (en) * 2010-07-02 2012-01-05 The University Of North Carolina At Chapel Hill Functionally selective ligands of dopamine d2 receptors
KR20140003438A (ko) 2010-11-15 2014-01-09 카톨리에케 유니버시테이트 루벤 항바이러스성 축합 헤테로사이클릭 화합물
KR20140072037A (ko) 2011-08-30 2014-06-12 씨에이치디아이 파운데이션, 인코포레이티드 키뉴레닌-3-모노옥시게나제 억제제, 약학적 조성물 및 이의 사용 방법
EA032526B1 (ru) 2011-08-30 2019-06-28 Схди Фаундейшн, Инк. Применение ингибитора кинуренин-3-монооксигеназы для лечения заболеваний и состояний, опосредованных активностью кинуренин-3-монооксигеназы
GEP20186871B (en) 2013-12-24 2018-06-25 Inc Oncotartis Benzamide and nicotinamide compounds and methods of using same
KR20170026633A (ko) 2014-07-17 2017-03-08 씨에이치디아이 파운데이션, 인코포레이티드 Hiv-관련 장애의 치료 방법 및 치료용 조성물

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BE628766A (cs) 1962-12-26
BE792206A (cs) 1971-12-02 1973-06-01 Byk Gulden Lomberg Chem Fab
US5139998A (en) 1988-08-31 1992-08-18 Superconductor Technologies, Inc. Controlled thallous oxide evaporation for thallium superconductor films and reactor design
SE8803429D0 (sv) * 1988-09-28 1988-09-28 Pharmacia Ab Novel pyridyl- and pyrimidyl derivatives
US5008267A (en) 1988-10-29 1991-04-16 Mitsui Toatsu Chemicals, Incorporated Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same
JP2815218B2 (ja) 1990-04-13 1998-10-27 三井化学株式会社 ピリミジンジオン誘導体、およびそれを含有する抗不整脈剤
FR2663638B2 (fr) 1990-04-06 1995-02-10 Institut Nal Sante Recherc Medic Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides.
JP2518965B2 (ja) 1990-09-21 1996-07-31 三井東圧化学株式会社 新規ピリジン誘導体及びそれを有効成分として含有する制癌剤効果増強剤
FR2668771B1 (fr) 1990-11-06 1995-03-17 Inst Nat Sante Rech Med Acides nucleiques codant pour des polypeptides ayant une activite de recepteur dopaminergique humain et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides.
DE4425145A1 (de) 1994-07-15 1996-01-18 Basf Ag Verwendung von Thiazol- und Thiadiazolverbindungen
DE4425146A1 (de) 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen
DE4425144A1 (de) 1994-07-15 1996-01-18 Basf Ag Triazolverbindungen und deren Verwendung
DE4425143A1 (de) 1994-07-15 1996-01-18 Basf Ag Substituierte Pyrimidinverbindungen und deren Verwendung
US5635503A (en) * 1995-06-07 1997-06-03 Bristol-Myers Squibb Company Dihydropyridine npy antagonists: piperazine derivatives
FR2742149B1 (fr) 1995-12-11 1998-02-13 Inst Nat Sante Rech Med Nouveaux derives de 2-naphtamides et leurs applications therapeutiques

Also Published As

Publication number Publication date
AU1440797A (en) 1997-08-01
NO983187L (no) 1998-09-09
KR100441073B1 (ko) 2004-11-16
US6352981B1 (en) 2002-03-05
CN1348956A (zh) 2002-05-15
MX9805499A (es) 1998-11-30
BG102616A (en) 1999-04-30
EP0877744B1 (de) 2004-08-11
IL125076A (en) 2001-05-20
DE19600934A1 (de) 1997-07-17
NO316753B1 (no) 2004-04-26
ZA97209B (en) 1998-07-10
HUP9901590A2 (hu) 1999-08-30
CN1075070C (zh) 2001-11-21
TW475929B (en) 2002-02-11
PL327692A1 (en) 1998-12-21
CZ215998A3 (cs) 1999-05-12
ES2225947T3 (es) 2005-03-16
DE59711847D1 (de) 2004-09-16
BG64098B1 (bg) 2003-12-31
SK94198A3 (en) 1999-03-12
CN1212692A (zh) 1999-03-31
HRP970021A2 (en) 1998-04-30
WO1997025324A1 (de) 1997-07-17
CZ297981B6 (cs) 2007-05-16
IL125076A0 (en) 1999-01-26
JP2000505072A (ja) 2000-04-25
AU717726B2 (en) 2000-03-30
AR005868A1 (es) 1999-07-21
HU228457B1 (en) 2013-03-28
CA2241787C (en) 2006-04-04
KR19990077127A (ko) 1999-10-25
ATE273301T1 (de) 2004-08-15
CO4790173A1 (es) 1999-05-31
NZ326332A (en) 1999-04-29
JP4349657B2 (ja) 2009-10-21
TR199801302T2 (xx) 1998-11-23
CN1146551C (zh) 2004-04-21
EP0877744A1 (de) 1998-11-18
US6214822B1 (en) 2001-04-10
CA2241787A1 (en) 1997-07-17
HUP9901590A3 (en) 2002-01-28

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Legal Events

Date Code Title Description
PC4A Assignment and transfer of rights

Owner name: ABBVIE DEUTSCHLAND GMBH & CO. KG, WIESBADEN, DE

Free format text: FORMER OWNER: ABBOTT GMBH & CO. KG, WIESBADEN, DE

Effective date: 20141020

MK4A Expiry of patent

Expiry date: 20170110