SK284601B6 - Použitie flurpirtinu na prípravu liečiva na liečenie HIV alebo AIDS - Google Patents

Použitie flurpirtinu na prípravu liečiva na liečenie HIV alebo AIDS Download PDF

Info

Publication number: SK284601B6
Authority: SK; Slovakia
Prior art keywords: flupirtine; cells; hiv; apoptosis; infected
Prior art date: 1995-11-07

Application number

SK586-98A

Other languages

English (en)

Slovak (sk)

Other versions

SK58698A3 (en

Inventor

Gabriela Pergande

Werner E. G. M�Ller

Original Assignee

Viatris Gmbh & Co. Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-07

Filing date

1996-10-23

Publication date

2005-07-01

1996-10-23 Application filed by Viatris Gmbh & Co. Kg filed Critical Viatris Gmbh & Co. Kg

1998-09-09 Publication of SK58698A3 publication Critical patent/SK58698A3/sk

2005-07-01 Publication of SK284601B6 publication Critical patent/SK284601B6/sk

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Oncology (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Polyurethanes Or Polyureas (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SK586-98A 1995-11-07 1996-10-23 Použitie flurpirtinu na prípravu liečiva na liečenie HIV alebo AIDS SK284601B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19541405A DE19541405A1 (de)	1995-11-07	1995-11-07	Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
PCT/DE1996/002009 WO1997017072A2 (de)	1995-11-07	1996-10-23	Verwendung von flupirtin zur prophylaxe und therapie von erkrankungen, die mit einer beeinträchtigung des hämatopoetischen zellsystems einhergehen

Publications (2)

Publication Number	Publication Date
SK58698A3 SK58698A3 (en)	1998-09-09
SK284601B6 true SK284601B6 (sk)	2005-07-01

Family

ID=7776799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK586-98A SK284601B6 (sk)	1995-11-07	1996-10-23	Použitie flurpirtinu na prípravu liečiva na liečenie HIV alebo AIDS

Country Status (27)

Country	Link
US (2)	US6034111A (zh)
EP (1)	EP0859613B1 (zh)
JP (1)	JPH11514652A (zh)
KR (1)	KR100512673B1 (zh)
CN (1)	CN1116037C (zh)
AT (1)	ATE316789T1 (zh)
AU (1)	AU711207B2 (zh)
BG (1)	BG63149B1 (zh)
BR (1)	BR9611588A (zh)
CA (1)	CA2189705C (zh)
CZ (1)	CZ298115B6 (zh)
DE (2)	DE19541405A1 (zh)
DK (1)	DK0859613T3 (zh)
ES (1)	ES2257755T3 (zh)
HK (1)	HK1016508A1 (zh)
HU (1)	HU225742B1 (zh)
MX (1)	MX9803610A (zh)
NO (1)	NO315074B1 (zh)
NZ (1)	NZ330414A (zh)
PL (1)	PL186537B1 (zh)
PT (1)	PT859613E (zh)
RU (1)	RU2200555C2 (zh)
SK (1)	SK284601B6 (zh)
TW (1)	TW393317B (zh)
UA (1)	UA51682C2 (zh)
WO (1)	WO1997017072A2 (zh)
ZA (1)	ZA968783B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19625582A1 (de) *	1996-06-27	1998-01-02	Asta Medica Ag	Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen die mit einer unphysiologisch hohen Zellsterberate einhergehen
US6821995B1 (en)	1999-12-01	2004-11-23	Duke University	Method of treating batten disease
DE10327674A1 (de)	2003-06-20	2005-01-05	Awd.Pharma Gmbh & Co. Kg	Injizierbare Darreichungsform von Flupirtin
EP1688141A1 (en) *	2005-01-31	2006-08-09	elbion AG	The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome
US20080279930A1 (en) *	2007-05-07	2008-11-13	Bernd Terhaag	Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
DE102009023162B4 (de) *	2009-05-29	2011-07-07	Corden PharmaChem GmbH, 68305	Verfahren zur Herstellung von Flupirtin
WO2011017495A1 (en) *	2009-08-07	2011-02-10	Swagelok Company	Low temperature carburization under soft vacuum
DE102010030053A1 (de)	2010-06-14	2011-12-15	Awd.Pharma Gmbh & Co.Kg	Injizierbare Darreichungsform von Flupirtin
US20150072006A1 (en) *	2012-03-02	2015-03-12	Meda Pharma Gmbh & Co. Kg	Pharmaceutical Formulations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN172468B (zh) *	1990-07-14	1993-08-14	Asta Medica Ag
DE4327516A1 (de) *	1993-08-17	1995-02-23	Asta Medica Ag	Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin

1995
- 1995-11-07 DE DE19541405A patent/DE19541405A1/de not_active Ceased
1996
- 1996-10-18 ZA ZA968783A patent/ZA968783B/xx unknown
- 1996-10-23 HU HU9901659A patent/HU225742B1/hu not_active IP Right Cessation
- 1996-10-23 CZ CZ0128398A patent/CZ298115B6/cs not_active IP Right Cessation
- 1996-10-23 ES ES96945822T patent/ES2257755T3/es not_active Expired - Lifetime
- 1996-10-23 PT PT96945822T patent/PT859613E/pt unknown
- 1996-10-23 AT AT96945822T patent/ATE316789T1/de active
- 1996-10-23 JP JP9517734A patent/JPH11514652A/ja active Pending
- 1996-10-23 PL PL96326629A patent/PL186537B1/pl not_active IP Right Cessation
- 1996-10-23 KR KR10-1998-0703376A patent/KR100512673B1/ko not_active IP Right Cessation
- 1996-10-23 SK SK586-98A patent/SK284601B6/sk not_active IP Right Cessation
- 1996-10-23 RU RU98111152/14A patent/RU2200555C2/ru not_active IP Right Cessation
- 1996-10-23 CN CN96198131A patent/CN1116037C/zh not_active Expired - Fee Related
- 1996-10-23 AU AU17165/97A patent/AU711207B2/en not_active Ceased
- 1996-10-23 UA UA98062946A patent/UA51682C2/uk unknown
- 1996-10-23 NZ NZ330414A patent/NZ330414A/en unknown
- 1996-10-23 EP EP96945822A patent/EP0859613B1/de not_active Expired - Lifetime
- 1996-10-23 BR BR9611588A patent/BR9611588A/pt not_active Application Discontinuation
- 1996-10-23 DK DK96945822T patent/DK0859613T3/da active
- 1996-10-23 DE DE59611327T patent/DE59611327D1/de not_active Expired - Lifetime
- 1996-10-23 WO PCT/DE1996/002009 patent/WO1997017072A2/de active IP Right Grant
- 1996-11-04 TW TW085113437A patent/TW393317B/zh not_active IP Right Cessation
- 1996-11-06 CA CA002189705A patent/CA2189705C/en not_active Expired - Fee Related
- 1996-11-07 US US08/744,953 patent/US6034111A/en not_active Expired - Lifetime
1998
- 1998-04-16 US US09/061,099 patent/US6034112A/en not_active Expired - Lifetime
- 1998-04-24 BG BG102404A patent/BG63149B1/bg unknown
- 1998-04-27 NO NO19981898A patent/NO315074B1/no not_active IP Right Cessation
- 1998-05-07 MX MX9803610A patent/MX9803610A/es not_active IP Right Cessation
1999
- 1999-04-21 HK HK99101726A patent/HK1016508A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1016508A1 (en)	1999-11-05
EP0859613B1 (de)	2006-02-01
JPH11514652A (ja)	1999-12-14
CN1201391A (zh)	1998-12-09
ES2257755T3 (es)	2006-08-01
WO1997017072A3 (de)	1997-07-24
CZ298115B6 (cs)	2007-06-27
ATE316789T1 (de)	2006-02-15
ZA968783B (en)	1997-05-27
US6034112A (en)	2000-03-07
BG102404A (en)	1998-12-30
BR9611588A (pt)	1999-04-06
NO981898L (no)	1998-04-27
PL186537B1 (pl)	2004-01-30
US6034111A (en)	2000-03-07
SK58698A3 (en)	1998-09-09
PL326629A1 (en)	1998-10-12
DE19541405A1 (de)	1997-05-15
RU2200555C2 (ru)	2003-03-20
HUP9901659A3 (en)	2001-04-28
PT859613E (pt)	2006-06-30
NO981898D0 (no)	1998-04-27
DE59611327D1 (de)	2006-04-13
DK0859613T3 (da)	2006-06-06
HUP9901659A2 (hu)	1999-09-28
KR100512673B1 (ko)	2005-12-09
CA2189705A1 (en)	1997-05-08
MX9803610A (es)	1998-09-30
UA51682C2 (uk)	2002-12-16
BG63149B1 (bg)	2001-05-31
AU1716597A (en)	1997-05-29
CN1116037C (zh)	2003-07-30
NO315074B1 (no)	2003-07-07
KR19990067366A (ko)	1999-08-16
AU711207B2 (en)	1999-10-07
TW393317B (en)	2000-06-11
EP0859613A2 (de)	1998-08-26
CZ128398A3 (cs)	1998-09-16
NZ330414A (en)	1999-10-28
CA2189705C (en)	2005-08-09
WO1997017072A2 (de)	1997-05-15
HU225742B1 (en)	2007-07-30

Publication	Publication Date	Title
CA2373883A1 (en)	2001-01-11	Method of reducing neuronal injury or apoptosis
Crowe	1995	Role of macrophages in the pathogenesis of human immunodeficiency virus (HIV) infection
SK284601B6 (sk)	2005-07-01	Použitie flurpirtinu na prípravu liečiva na liečenie HIV alebo AIDS
JPH07173063A (ja)	1995-07-11	製薬学的に活性な化合物を含有するマラリヤの治療剤
WO1997017072A9 (de)	1997-08-21	Verwendung von flupirtin zur prophylaxe und therapie von erkrankungen, die mit einer beeinträchtigung des hämatopoetischen zellsystems einhergehen
SK24098A3 (en)	1998-09-09	Combinatory composition for the treatment of dementia
CA2174552A1 (en)	1995-04-27	Flavin derivatives as anti-viral agents
JPH0521891B2 (zh)	1993-03-25
EP1075270B1 (en)	2005-06-15	Short peptide for treatment of neurological degenerative diseases
Rosengarten et al.	1993	A subpopulation of dopamine D1 receptors mediate repetitive jaw movements in rats
EP0476391B1 (en)	1996-04-10	Anti-AIDS virus composition containing cepharanthine as active compound
US20020198247A1 (en)	2002-12-26	Pharmaceutical composition for inhibiting the growth of viruses and cancers
Müller et al.	1997	Flupirtine protects both neuronal cells and lymphocytes against induced apoptosis in vitro: implications for treatment of AIDS patients
WO1992007564A2 (en)	1992-05-14	Method of treating demyelinating disease
CA2064112C (en)	2002-12-31	.alpha.-dihydroergocryptine pharmaceutical preparations with neuroprotective activity
WO2002072025A2 (en)	2002-09-19	Improving postsynaptic response by a combination of 4-minopyridine and agonist
Dearsly et al.	1987	Sexual development in Plasmodium berghei: the use of mitomycin C to separate infective gametocytes in vivo and ookinetes in vitro
NZ242264A (en)	1995-02-24	Polyadenylic acid/polyuridylic acid complexes in pharmaceutical compositions
HUT58523A (en)	1992-03-30	Process for producing antiviral compositions from modified gangliosides
CA2251800A1 (en)	1997-10-23	Nitrone free radical trap treatment of dementia associated with aids virus (hiv-1) infection
WO2007131488A2 (de)	2007-11-22	Verwendung von chinolonderivaten als anti-protozoäre mittel und in kombinatinonspräparaten

Legal Events

Date	Code	Title	Description
2014-07-02	MM4A	Patent lapsed due to non-payment of maintenance fees	Effective date: 20131023