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SI3160984T1 - Postopek za pripravo D-arginil-2,6-dimetil-L-tirosil-L-lisil-L-fenilalaninamida - Google Patents

Postopek za pripravo D-arginil-2,6-dimetil-L-tirosil-L-lisil-L-fenilalaninamida

Info

Publication number
SI3160984T1
SI3160984T1 SI201531587T SI201531587T SI3160984T1 SI 3160984 T1 SI3160984 T1 SI 3160984T1 SI 201531587 T SI201531587 T SI 201531587T SI 201531587 T SI201531587 T SI 201531587T SI 3160984 T1 SI3160984 T1 SI 3160984T1
Authority
SI
Slovenia
Prior art keywords
phenylalaninamide
tyrosyl
arginyl
lysyl
dimethyl
Prior art date
Application number
SI201531587T
Other languages
English (en)
Inventor
Xinjun Zhao
Minyu Zheng
Xiaozhong Yu
Hanrong Gao
Fabrice Cornille
Original Assignee
Flamma S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flamma S.P.A. filed Critical Flamma S.P.A.
Publication of SI3160984T1 publication Critical patent/SI3160984T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201531587T 2014-06-25 2015-06-24 Postopek za pripravo D-arginil-2,6-dimetil-L-tirosil-L-lisil-L-fenilalaninamida SI3160984T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462016783P 2014-06-25 2014-06-25
EP15738001.5A EP3160984B1 (en) 2014-06-25 2015-06-24 Process for preparing d-arginyl-2,6-dimethyl-l-tyrosyl-l-lysyl-l-phenylalaninamide
PCT/EP2015/064301 WO2015197723A1 (en) 2014-06-25 2015-06-24 Process for preparing d-arginyl-2,6-dimethyl-l-tyrosyl-l-lysyl-l-phenylalaninamide

Publications (1)

Publication Number Publication Date
SI3160984T1 true SI3160984T1 (sl) 2021-08-31

Family

ID=53546576

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201531587T SI3160984T1 (sl) 2014-06-25 2015-06-24 Postopek za pripravo D-arginil-2,6-dimetil-L-tirosil-L-lisil-L-fenilalaninamida

Country Status (8)

Country Link
US (1) US10125164B2 (sl)
EP (1) EP3160984B1 (sl)
JP (1) JP2017523956A (sl)
ES (1) ES2869430T3 (sl)
HU (1) HUE054626T2 (sl)
PL (1) PL3160984T3 (sl)
SI (1) SI3160984T1 (sl)
WO (1) WO2015197723A1 (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016539931A (ja) * 2013-10-23 2016-12-22 株式会社カネカ テトラペプチド化合物及びその製造方法
JP2017523957A (ja) * 2014-06-30 2017-08-24 フラマ ソシエタ ペル アチオニＦｌａｍｍａ Ｓ．Ｐ．Ａ． Ｄ−アルギニル−２，６−ジメチル−ｌ−チロシル−ｌ−リシル−ｌ−フェニルアラニンアミドの製造方法
US11795196B2 (en) 2017-12-15 2023-10-24 Stealth Biotherapeutics Inc. Mitochondria-targeting peptides
AU2018385690B2 (en) * 2017-12-15 2023-07-27 Stealth Biotherapeutics Inc. Mitochondria-targeting peptides
US20230227499A1 (en) * 2020-06-22 2023-07-20 Stealth Biotherapeutics Inc. Prodrugs of mitochondria-targeting oligopeptides

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1184317B (it) * 1985-02-05 1987-10-28 Eniricerche Spa Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a
SE9900961D0 (sv) 1999-03-16 1999-03-16 Astra Ab Novel compounds
ES2605504T3 (es) 2003-02-04 2017-03-14 Cornell Research Foundation, Inc. Usos de un péptido aromático catiónico
BRPI0409911A (pt) * 2003-05-01 2006-04-25 Cornell Res Foundation Inc método para liberar uma molécula em uma célula, e, complexo carreador
CA2554166C (en) 2004-01-23 2014-07-29 Cornell Research Foundation, Inc. Methods for reducing oxidative damage
WO2007027742A2 (en) * 2005-08-31 2007-03-08 The Trustees Of The University Of Pennsylvania SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS
JP5171613B2 (ja) * 2006-03-01 2013-03-27 株式会社カネカ ペプチドの製造方法
CN101951936A (zh) 2008-02-26 2011-01-19 康奈尔大学 用于防止和治疗急性肾损伤的方法
US20110245182A1 (en) 2010-04-06 2011-10-06 Perricone Nicholas V Topical Uses of Szeto-Schiller Peptides
US20110245183A1 (en) 2010-04-06 2011-10-06 Perricone Nicholas V Topical Uses of Szeto-Schiller Peptides
US20120083452A1 (en) 2010-09-30 2012-04-05 Perricone Nicholas V Topical Anesthetic Uses of Szeto-Schiller Peptides
EP2720704A4 (en) 2011-06-14 2015-06-10 Stealth Peptides Int Inc AROMATIC-CATIONIC PEPTIDES AND USES THEREOF
AU2012347931A1 (en) 2011-12-09 2014-07-03 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
WO2014210056A1 (en) 2013-06-27 2014-12-31 Stealth Peptides International, Inc. Peptide therapeutics and methods for using same
JP2016539931A (ja) * 2013-10-23 2016-12-22 株式会社カネカ テトラペプチド化合物及びその製造方法
JP6626446B2 (ja) 2013-12-27 2019-12-25 ステルス バイオセラピューティックス コープ 薬学的に適切な芳香族カチオン性ペプチド
JP2017523957A (ja) * 2014-06-30 2017-08-24 フラマ ソシエタ ペル アチオニＦｌａｍｍａ Ｓ．Ｐ．Ａ． Ｄ−アルギニル−２，６−ジメチル−ｌ−チロシル−ｌ−リシル−ｌ−フェニルアラニンアミドの製造方法

Also Published As

Publication number Publication date
HUE054626T2 (hu) 2021-09-28
US20170129920A1 (en) 2017-05-11
US10125164B2 (en) 2018-11-13
PL3160984T3 (pl) 2021-10-25
ES2869430T3 (es) 2021-10-25
WO2015197723A1 (en) 2015-12-30
EP3160984A1 (en) 2017-05-03
JP2017523956A (ja) 2017-08-24
EP3160984B1 (en) 2021-04-14

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