SI2628746T1 - Proces za koncentriranje polipeptida - Google Patents

Proces za koncentriranje polipeptida

Info

Publication number: SI2628746T1
Authority: SI; Slovenia
Prior art keywords: polypeptide; concentration
Prior art date: 2006-04-04

Application number

SI200732097T

Other languages

English (en)

Inventor

Stefan Nilsson

Original Assignee

Chiesi Farmaceutici S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-04

Filing date

2007-04-04

Publication date

2019-04-30

2007-04-04 Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.

2019-04-30 Publication of SI2628746T1 publication Critical patent/SI2628746T1/sl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/01061—Hydroxymethylbilane synthase (2.5.1.61)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/06—Sulfuric ester hydrolases (3.1.6)
- C12Y301/06001—Arylsulfatase (3.1.6.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01024—Alpha-mannosidase (3.2.1.24)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01046—Galactosylceramidase (3.2.1.46)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/06—Sulfuric ester hydrolases (3.1.6)
- C12Y301/06008—Cerebroside-sulfatase (3.1.6.8)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Water Supply & Treatment (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Psychiatry (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

SI200732097T 2006-04-04 2007-04-04 Proces za koncentriranje polipeptida SI2628746T1 (sl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DKPA200600488		2006-04-04
DKPA200600922		2006-07-05
EP13167427.7A EP2628746B1 (en)	2006-04-04	2007-04-04	A process for the concentration of a polypeptide

Publications (1)

Publication Number	Publication Date
SI2628746T1 true SI2628746T1 (sl)	2019-04-30

Family

ID=38472949

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200732097T SI2628746T1 (sl)	2006-04-04	2007-04-04	Proces za koncentriranje polipeptida

Country Status (20)

Country	Link
US (6)	US20090246187A1 (sl)
EP (4)	EP2004672B1 (sl)
JP (6)	JP2009532394A (sl)
KR (3)	KR20140057678A (sl)
CN (1)	CN105233276A (sl)
AU (2)	AU2007234195B2 (sl)
BR (1)	BRPI0709737A2 (sl)
CA (3)	CA2644642C (sl)
DK (1)	DK2628746T3 (sl)
ES (3)	ES2744499T3 (sl)
HU (1)	HUE042402T2 (sl)
IL (4)	IL194267A (sl)
MX (1)	MX2008012748A (sl)
NO (3)	NO347673B1 (sl)
NZ (7)	NZ623123A (sl)
PL (3)	PL2100898T3 (sl)
PT (1)	PT2628746T (sl)
SI (1)	SI2628746T1 (sl)
WO (1)	WO2007112757A2 (sl)
ZA (2)	ZA200805346B (sl)

Families Citing this family (16)

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WO2005073367A1 (en)	2004-01-30	2005-08-11	Zymenex A/S	Production and purification of recombinant arylsulfatase a
AU2007234195B2 (en)	2006-04-04	2013-02-07	Takeda Pharmaceutical Company Limited	A process for concentration of a polypeptide
NZ601790A (en)	2010-02-24	2014-03-28	Zymenex As	Process for production and purification of recombinant lysosomal alpha-mannosidase
MX344795B (es) *	2010-06-25	2017-01-05	Shire Human Genetic Therapies	Composiciones y metodos para suministro al sistema nervioso central de arilsulfatasa a.
PE20180130A1 (es)	2010-06-25	2018-01-18	Shire Human Genetic Therapies	Composiciones y metodos para suministro al sistema nervioso central de arilsulfatasa a
KR102007044B1 (ko)	2010-06-25	2019-08-02	샤이어 휴먼 지네틱 테라피즈 인크.	치료제들의 cns 전달
JP6073783B2 (ja)	2010-06-25	2017-02-01	シャイアーヒューマンジェネティックセラピーズインコーポレイテッド	ヘパランｎ−スルファターゼのｃｎｓ送達のための方法および組成物
WO2013009686A2 (en)	2011-07-08	2013-01-17	Shire Human Genetic Therapies, Inc.	Methods for purification of arylsulfatase a
US20140377244A1 (en)	2011-12-23	2014-12-25	Shire Human Genetic Therapies, Inc.	Stable formulations for cns delivery of arylsulfatase a
CA2890358C (en) *	2012-11-13	2020-02-11	Ace Biosciences A/S	Purification of recombinant human galactocerebroside .beta.-galactosidase (rhgalc)
JP2016506501A (ja) *	2012-12-11	2016-03-03	セントジーンアーゲー	異染性白質ジストロフィーの診断方法
WO2014110246A1 (en)	2013-01-09	2014-07-17	Shire Human Genetic Therapies, Inc.	Methods for purification of arylsulfatase a
EA037906B1 (ru)	2013-03-15	2021-06-04	Биовератив Терапьютикс Инк.	Препараты полипептида фактора ix
SG10201913735SA (en)	2014-03-24	2020-03-30	Bioverativ Therapeutics Inc	Lyophilized factor ix formulations
JP6957738B2 (ja) *	2017-08-31	2021-11-02	グリーン・クロス・コーポレイションＧｒｅｅｎＣｒｏｓｓＣｏｒｐ．	スルファターゼタンパク質を精製する方法
KR102290596B1 (ko) *	2020-09-10	2021-08-19	주식회사 파이안바이오테크놀로지	분리된 미토콘드리아를 포함하는 주사용 조성물 및 이의 용도

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ATE217799T1 (de)	1998-01-27	2002-06-15	Hemebiotech As	Behandlung von akuter intermittierender porphyria oder anderen porphyrischen krankheiten
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AU2002317701A1 (en) *	2001-06-07	2002-12-16	Hemebiotech A/S	Production of recombinant human lysosomal alpha-mannosidase
WO2002098455A2 (en) *	2001-06-07	2002-12-12	Hemebiotech A/S	Production of recombinant human arylsulfatase a
WO2003002731A1 (en)	2001-06-29	2003-01-09	Hemebiotech A/S	A PROCESS FOR PURIFICATION OF RECOMBINANT PORPHOBILINOGEN DEAMINASE (rhPBGD)
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WO2005073367A1 (en) *	2004-01-30	2005-08-11	Zymenex A/S	Production and purification of recombinant arylsulfatase a
EP1740204B1 (en)	2004-04-01	2018-03-14	Chiesi Farmaceutici S.p.A.	Medicinal use of alpha-mannosidase
US20060051347A1 (en) *	2004-09-09	2006-03-09	Winter Charles M	Process for concentration of antibodies and therapeutic products thereof
AU2007234195B2 (en) *	2006-04-04	2013-02-07	Takeda Pharmaceutical Company Limited	A process for concentration of a polypeptide

2007
- 2007-04-04 AU AU2007234195A patent/AU2007234195B2/en active Active
- 2007-04-04 SI SI200732097T patent/SI2628746T1/sl unknown
- 2007-04-04 MX MX2008012748A patent/MX2008012748A/es active IP Right Grant
- 2007-04-04 EP EP07711305.8A patent/EP2004672B1/en active Active
- 2007-04-04 US US12/295,848 patent/US20090246187A1/en not_active Abandoned
- 2007-04-04 NZ NZ62312307A patent/NZ623123A/en unknown
- 2007-04-04 EP EP08166902.0A patent/EP2100898B1/en active Active
- 2007-04-04 NZ NZ568728A patent/NZ568728A/en unknown
- 2007-04-04 KR KR1020147010563A patent/KR20140057678A/ko active Application Filing
- 2007-04-04 NZ NZ607595A patent/NZ607595A/en unknown
- 2007-04-04 CN CN201510510807.4A patent/CN105233276A/zh active Pending
- 2007-04-04 NZ NZ597548A patent/NZ597548A/xx unknown
- 2007-04-04 PT PT13167427T patent/PT2628746T/pt unknown
- 2007-04-04 PL PL08166902T patent/PL2100898T3/pl unknown
- 2007-04-04 NZ NZ582045A patent/NZ582045A/en unknown
- 2007-04-04 HU HUE13167427A patent/HUE042402T2/hu unknown
- 2007-04-04 CA CA2644642A patent/CA2644642C/en active Active
- 2007-04-04 CA CA2882501A patent/CA2882501C/en active Active
- 2007-04-04 KR KR1020087026971A patent/KR101504969B1/ko active IP Right Grant
- 2007-04-04 WO PCT/DK2007/000177 patent/WO2007112757A2/en active Application Filing
- 2007-04-04 KR KR1020157023398A patent/KR20150103339A/ko not_active Application Discontinuation
- 2007-04-04 ES ES08166902T patent/ES2744499T3/es active Active
- 2007-04-04 PL PL13167427T patent/PL2628746T3/pl unknown
- 2007-04-04 PL PL13167428.5T patent/PL2631242T3/pl unknown
- 2007-04-04 ES ES13167427T patent/ES2713488T3/es active Active
- 2007-04-04 CA CA2632528A patent/CA2632528C/en active Active
- 2007-04-04 EP EP13167428.5A patent/EP2631242B1/en active Active
- 2007-04-04 EP EP13167427.7A patent/EP2628746B1/en active Active
- 2007-04-04 NZ NZ588903A patent/NZ588903A/xx unknown
- 2007-04-04 BR BRPI0709737-9A patent/BRPI0709737A2/pt not_active Application Discontinuation
- 2007-04-04 NO NO20211305A patent/NO347673B1/no unknown
- 2007-04-04 DK DK13167427.7T patent/DK2628746T3/en active
- 2007-04-04 ES ES13167428T patent/ES2928096T3/es active Active
- 2007-04-04 NZ NZ571610A patent/NZ571610A/en unknown
- 2007-04-04 JP JP2009503414A patent/JP2009532394A/ja active Pending
2008
- 2008-05-30 NO NO20082510A patent/NO20082510L/no not_active Application Discontinuation
- 2008-06-19 ZA ZA2008/05346A patent/ZA200805346B/en unknown
- 2008-09-22 IL IL194267A patent/IL194267A/en active IP Right Grant
- 2008-09-26 AU AU2008229659A patent/AU2008229659B2/en active Active
- 2008-11-07 ZA ZA2008/09540A patent/ZA200809540B/en unknown
- 2008-11-12 NO NO20084776A patent/NO346368B1/no unknown
2009
- 2009-07-09 JP JP2009162789A patent/JP5384232B2/ja active Active
2011
- 2011-03-24 IL IL211905A patent/IL211905A0/en unknown
- 2011-04-26 US US13/094,321 patent/US8809055B2/en active Active
2013
- 2013-06-12 JP JP2013123735A patent/JP2013236633A/ja active Pending
- 2013-10-02 JP JP2013207365A patent/JP2014058521A/ja not_active Withdrawn
- 2013-10-02 JP JP2013207384A patent/JP5878152B2/ja active Active
2014
- 2014-07-01 US US14/321,642 patent/US20140314735A1/en not_active Abandoned
- 2014-11-30 IL IL235982A patent/IL235982A0/en unknown
2015
- 2015-09-16 IL IL241654A patent/IL241654B/en active IP Right Grant
- 2015-11-16 JP JP2015223865A patent/JP2016104000A/ja active Pending
2016
- 2016-02-11 US US15/041,841 patent/US9713634B2/en active Active
2017
- 2017-03-29 US US15/473,460 patent/US20170202927A1/en not_active Abandoned
- 2017-05-03 US US15/585,916 patent/US20180289777A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NO20084776L (no)	2008-10-31
WO2007112757A2 (en)	2007-10-11
EP2628746A2 (en)	2013-08-21
NO20082510L (no)	2008-10-31
EP2100898A1 (en)	2009-09-16
NZ607595A (en)	2014-10-31
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