SI2274321T1 - Opiorfinski peptidni derivati kot učinkoviti inhibitorji enkefalin-degradirajočih ektopeptidaz - Google Patents

Opiorfinski peptidni derivati kot učinkoviti inhibitorji enkefalin-degradirajočih ektopeptidaz

Info

Publication number: SI2274321T1
Authority: SI; Slovenia
Prior art keywords: ectopetidases; enkephalin; degrading; peptide derivatives; potent inhibitors
Prior art date: 2008-04-07

Application number

SI200931942T

Other languages

English (en)

Inventor

Catherine Rougeot

Original Assignee

Institut Pasteur

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-04-07

Filing date

2009-04-07

Publication date

2019-04-30

2009-04-07 Application filed by Institut Pasteur filed Critical Institut Pasteur

2019-04-30 Publication of SI2274321T1 publication Critical patent/SI2274321T1/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Reproductive Health (AREA)
Neurology (AREA)
Endocrinology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SI200931942T 2008-04-07 2009-04-07 Opiorfinski peptidni derivati kot učinkoviti inhibitorji enkefalin-degradirajočih ektopeptidaz SI2274321T1 (sl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US4292208P	2008-04-07	2008-04-07
PCT/EP2009/054171 WO2009124948A1 (en)	2008-04-07	2009-04-07	Opiorphin peptide derivatives as potent inhibitors of enkephalin - degrading ectopetidases
EP09730759.9A EP2274321B1 (en)	2008-04-07	2009-04-07	Opiorphin peptide derivatives as potent inhibitors of enkephalin - degrading ectopetidases

Publications (1)

Publication Number	Publication Date
SI2274321T1 true SI2274321T1 (sl)	2019-04-30

Family

ID=40956908

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200931942T SI2274321T1 (sl)	2008-04-07	2009-04-07	Opiorfinski peptidni derivati kot učinkoviti inhibitorji enkefalin-degradirajočih ektopeptidaz

Country Status (21)

Country	Link
US (3)	US8642729B2 (sl)
EP (1)	EP2274321B1 (sl)
JP (2)	JP5788788B2 (sl)
KR (1)	KR20110028433A (sl)
CN (1)	CN102083851A (sl)
AU (1)	AU2009235484B2 (sl)
BR (1)	BRPI0906905B1 (sl)
CA (1)	CA2720778C (sl)
CY (1)	CY1121966T1 (sl)
DK (1)	DK2274321T3 (sl)
ES (1)	ES2714374T3 (sl)
HR (1)	HRP20190335T1 (sl)
HU (1)	HUE042998T2 (sl)
IL (1)	IL208543A (sl)
LT (1)	LT2274321T (sl)
MX (1)	MX2010011055A (sl)
PL (1)	PL2274321T3 (sl)
PT (1)	PT2274321T (sl)
RU (2)	RU2542365C2 (sl)
SI (1)	SI2274321T1 (sl)
WO (1)	WO2009124948A1 (sl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2390075T3 (es)	2004-03-19	2012-11-06	Institut Pasteur	Péptidos derivados de la proteína BPLP humana, polinucleótidos que codifican dichos péptidos y anticuerpos dirigidos contra dichos péptidos
SI2274321T1 (sl)	2008-04-07	2019-04-30	Institut Pasteur	Opiorfinski peptidni derivati kot učinkoviti inhibitorji enkefalin-degradirajočih ektopeptidaz
FR2931362B1 (fr) *	2008-05-26	2017-08-18	Pasteur Institut	L'opiorphine pour une utilisation en tant que psychostimulant.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2637600B1 (fr) *	1988-10-11	1992-03-06	Pasteur Institut	Peptides et polypeptides provenant de la glande sous maxillaire du rat, anticorps monoclonaux et polyclonaux correspondants, hybridomes correspondants et applications de ces produits au diagnostic, a la detection ou a des fins therapeutiques
US6184205B1 (en) *	1994-07-22	2001-02-06	University Of North Carolina At Chapel Hill	GRB2 SH3 binding peptides and methods of isolating and using same
US6589750B2 (en)	1997-02-20	2003-07-08	Institut Pasteur	Therapeutic use of the SMR1 protein, the SMR1 maturation products, specifically the QHNPR pentapeptide as well as its biologically active derivatives
ES2315753T3 (es)	1999-06-23	2009-04-01	Institut Pasteur	Composiciones para el tratamiento de problemas de relaciones interpersonales y trastornos del comportamiento.
DE60018085T2 (de)	2000-12-22	2005-07-07	Institut Pasteur	Prozess zum Screening von Molekülen, die spezifisch an die NEP-Bindungsstelle des QHNPR-pentapeptides binden
RU2223113C1 (ru) *	2002-05-29	2004-02-10	Золотарев Юрий Александрович	Пептид, обладающий регулирующей биологической активностью на белковый синтез в гепатоцитах
ES2390075T3 (es)	2004-03-19	2012-11-06	Institut Pasteur	Péptidos derivados de la proteína BPLP humana, polinucleótidos que codifican dichos péptidos y anticuerpos dirigidos contra dichos péptidos
WO2008009276A1 (de) *	2006-07-21	2008-01-24	Jenoptik Laser, Optik, Systeme Gmbh	Lateral verstellbare fassung für optische elemente
BRPI0807207A2 (pt)	2007-02-02	2014-06-17	Greenpharma Sas	Composto que inibe metalo-ectopeptidase, composição contendo composto, uso do composto e processo de tratamento cosmético da pele humana ou na membrana mucosa
WO2009090265A1 (en)	2008-01-18	2009-07-23	Institut Pasteur	Method for identifying bplp and opiorphin agonists or antagonists
SI2274321T1 (sl) *	2008-04-07	2019-04-30	Institut Pasteur	Opiorfinski peptidni derivati kot učinkoviti inhibitorji enkefalin-degradirajočih ektopeptidaz
FR2931362B1 (fr)	2008-05-26	2017-08-18	Pasteur Institut	L'opiorphine pour une utilisation en tant que psychostimulant.
CA2645452A1 (en)	2008-11-28	2010-05-28	Institut Pasteur	Use of basic prolin-rich lacrimal gene products, such as opiorphin, as a biomarker

2009
- 2009-04-07 SI SI200931942T patent/SI2274321T1/sl unknown
- 2009-04-07 AU AU2009235484A patent/AU2009235484B2/en not_active Ceased
- 2009-04-07 PL PL09730759T patent/PL2274321T3/pl unknown
- 2009-04-07 EP EP09730759.9A patent/EP2274321B1/en active Active
- 2009-04-07 CN CN2009801212936A patent/CN102083851A/zh active Pending
- 2009-04-07 DK DK09730759.9T patent/DK2274321T3/en active
- 2009-04-07 RU RU2010145158/04A patent/RU2542365C2/ru active
- 2009-04-07 WO PCT/EP2009/054171 patent/WO2009124948A1/en active Application Filing
- 2009-04-07 JP JP2011503426A patent/JP5788788B2/ja active Active
- 2009-04-07 CA CA2720778A patent/CA2720778C/en active Active
- 2009-04-07 BR BRPI0906905-4A patent/BRPI0906905B1/pt active IP Right Grant
- 2009-04-07 US US12/419,426 patent/US8642729B2/en active Active
- 2009-04-07 MX MX2010011055A patent/MX2010011055A/es active IP Right Grant
- 2009-04-07 HU HUE09730759A patent/HUE042998T2/hu unknown
- 2009-04-07 US US12/936,591 patent/US8889827B2/en active Active
- 2009-04-07 LT LTEP09730759.9T patent/LT2274321T/lt unknown
- 2009-04-07 PT PT09730759T patent/PT2274321T/pt unknown
- 2009-04-07 ES ES09730759T patent/ES2714374T3/es active Active
- 2009-04-07 KR KR1020107024984A patent/KR20110028433A/ko not_active Application Discontinuation
2010
- 2010-10-07 IL IL208543A patent/IL208543A/en active IP Right Grant
2014
- 2014-11-11 US US14/537,929 patent/US9273094B2/en active Active
- 2014-12-29 RU RU2014153924A patent/RU2014153924A/ru not_active Application Discontinuation
2015
- 2015-02-23 JP JP2015032997A patent/JP2015110651A/ja active Pending
2019
- 2019-02-20 HR HRP20190335TT patent/HRP20190335T1/hr unknown
- 2019-03-01 CY CY20191100256T patent/CY1121966T1/el unknown

Also Published As

Publication number	Publication date
AU2009235484B2 (en)	2013-11-07
LT2274321T (lt)	2019-03-12
HRP20190335T1 (hr)	2019-05-03
IL208543A0 (en)	2010-12-30
US20110124571A1 (en)	2011-05-26
CA2720778A1 (en)	2009-10-15
BRPI0906905A2 (pt)	2021-06-29
CY1121966T1 (el)	2020-10-14
US8889827B2 (en)	2014-11-18
CA2720778C (en)	2017-10-17
CN102083851A (zh)	2011-06-01
US8642729B2 (en)	2014-02-04
MX2010011055A (es)	2011-02-21
RU2014153924A (ru)	2016-07-20
EP2274321A1 (en)	2011-01-19
US20090253639A1 (en)	2009-10-08
EP2274321B1 (en)	2018-12-05
JP2015110651A (ja)	2015-06-18
RU2010145158A (ru)	2012-05-20
PL2274321T3 (pl)	2019-06-28
HUE042998T2 (hu)	2019-07-29
IL208543A (en)	2016-10-31
ES2714374T3 (es)	2019-05-28
US9273094B2 (en)	2016-03-01
AU2009235484A1 (en)	2009-10-15
BRPI0906905B1 (pt)	2022-09-13
US20150065683A1 (en)	2015-03-05
JP5788788B2 (ja)	2015-10-07
JP2011517940A (ja)	2011-06-23
KR20110028433A (ko)	2011-03-18
WO2009124948A1 (en)	2009-10-15
DK2274321T3 (en)	2019-03-18
PT2274321T (pt)	2019-03-21
RU2542365C2 (ru)	2015-02-20

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HK1156306A1 (en)	2012-06-08	Substituted dihydropyrazolones as inhibitors of hif-prolyl-4-hydroxylases hif--4-
EP2318395A4 (en)	2011-10-26	IPA INHIBITORS
ZA201201366B (en)	2013-09-25	Heterocycic derivatives as inhibitors of glutaminyl cyclase
EP2470183A4 (en)	2013-05-01	Heterocyclic amide compounds as protein kinase inhibitors
EP2249650A4 (en)	2012-01-11	ANILINOPYRIDINE AS A FAK HEMMER
HK1161680A1 (en)	2012-08-03	Pyrazolylaminopyridines as inhibitors of fak fak
ZA201007431B (en)	2013-03-27	Imidazolidinone derivatives as 11b-hsd1 inhibitors
EP2237793A4 (en)	2013-07-31	INHIBITORS OF CATHEPSIN B
IL196000A0 (en)	2009-09-01	2-arylindole derivatives as npges-i inhibitors
ZA201004765B (en)	2011-09-28	Inhibitors of iap
EP2318401A4 (en)	2013-10-30	AZAINDOLI INHIBITORS OF IPA
HRP20190335T1 (hr)	2019-05-03	Derivati opiorfin peptida kao učinkoviti inhibitori enkefalin - degradirajućih ektopeptidaza
EP2270141A4 (en)	2011-08-24	Lacritin PART PEPTIDE
GB0807451D0 (en)	2008-05-28	Inhibitors of PLK
GB0808286D0 (en)	2008-06-11	Inhibitors of HSP90
GB0803895D0 (en)	2008-04-09	Inhibitors of glyoxalase
GB0821710D0 (en)	2008-12-31	Derivatives of dihydroindolone
PL386302A1 (pl)	2010-04-26	Nowa pochodna izotiazolopirydyny