SI2247558T2 - Nova kontrastna sredstva za zaznavanje nevroloških disfunkcij - Google Patents
Nova kontrastna sredstva za zaznavanje nevroloških disfunkcijInfo
- Publication number
- SI2247558T2 SI2247558T2 SI200932157T SI200932157T SI2247558T2 SI 2247558 T2 SI2247558 T2 SI 2247558T2 SI 200932157 T SI200932157 T SI 200932157T SI 200932157 T SI200932157 T SI 200932157T SI 2247558 T2 SI2247558 T2 SI 2247558T2
- Authority
- SI
- Slovenia
- Prior art keywords
- imaging agents
- neurological dysfunction
- novel imaging
- detecting neurological
- detecting
- Prior art date
Links
- 239000012216 imaging agent Substances 0.000 title 1
- 230000009251 neurologic dysfunction Effects 0.000 title 1
- 208000015015 neurological dysfunction Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6610108P | 2008-02-14 | 2008-02-14 | |
PCT/US2009/000961 WO2009102498A1 (en) | 2008-02-14 | 2009-02-17 | Novel imaging agents for detecting neurological dysfunction |
EP09711194.2A EP2247558B2 (en) | 2008-02-14 | 2009-02-17 | Novel imaging agents for detecting neurological dysfunction |
Publications (2)
Publication Number | Publication Date |
---|---|
SI2247558T1 SI2247558T1 (sl) | 2022-07-29 |
SI2247558T2 true SI2247558T2 (sl) | 2024-10-30 |
Family
ID=40627498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200932157T SI2247558T2 (sl) | 2008-02-14 | 2009-02-17 | Nova kontrastna sredstva za zaznavanje nevroloških disfunkcij |
Country Status (16)
Country | Link |
---|---|
US (2) | US8318132B2 (sl) |
EP (2) | EP2599763A1 (sl) |
JP (1) | JP2011512354A (sl) |
KR (1) | KR20100135235A (sl) |
CA (1) | CA2715390A1 (sl) |
CY (1) | CY1125258T1 (sl) |
DK (1) | DK2247558T4 (sl) |
ES (1) | ES2907992T3 (sl) |
FI (1) | FI2247558T4 (sl) |
HR (1) | HRP20220401T4 (sl) |
HU (1) | HUE058352T2 (sl) |
LT (1) | LT2247558T (sl) |
PL (1) | PL2247558T5 (sl) |
PT (1) | PT2247558T (sl) |
SI (1) | SI2247558T2 (sl) |
WO (1) | WO2009102498A1 (sl) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8932557B2 (en) | 2008-02-14 | 2015-01-13 | Eli Lilly And Company | Imaging agents for detecting neurological dysfunction |
SI2247558T2 (sl) | 2008-02-14 | 2024-10-30 | Eli Lilly And Company | Nova kontrastna sredstva za zaznavanje nevroloških disfunkcij |
CA2733499A1 (en) * | 2008-08-08 | 2010-02-11 | Neurosearch A/S | Novel diphenyl 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors |
MX349711B (es) * | 2008-09-18 | 2017-08-09 | Cedars Sinai Medical Center | Método óptico para la detección de la enfermedad de alzheimer. |
US8691187B2 (en) * | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
GB201016038D0 (en) | 2010-09-24 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method |
SG10201508766UA (en) * | 2010-10-29 | 2015-11-27 | Clino Ltd | Tau imaging probe |
CA2844511A1 (en) * | 2011-08-11 | 2013-02-14 | Neuprotect Pty Ltd | Flavonoid compounds, and methods of use thereof |
US20130315825A1 (en) * | 2012-05-03 | 2013-11-28 | Washington University | Tricyclic heteroaromatic compounds as alpha-synuclein ligands |
EP2852572B1 (en) * | 2012-05-22 | 2020-04-01 | Eli Lilly and Company | Carboline and carbazole based imaging agents for detecting neurological dysfunction |
EP2767532B1 (en) | 2012-12-21 | 2016-07-13 | National Institutes for Quantum and Radiological Science and Technology | Novel compound for imaging tau protein accumulated in the brain |
US20160115162A1 (en) | 2013-05-31 | 2016-04-28 | The General Hospital Corporation | Radiosynthesis of Tau Radiopharmaceuticals |
UY35625A (es) | 2013-06-25 | 2014-12-31 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Compuestos de tetrahidrocarbazol y carbazol carboxamida sustituidos como inhibidores de quinasa |
JP6353530B2 (ja) | 2013-06-25 | 2018-07-04 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | キナーゼ阻害剤として有用なカルバゾールカルボキサミド化合物 |
EA028483B1 (ru) * | 2013-10-08 | 2017-11-30 | Ф. Хоффманн-Ля Рош Аг | ПРОИЗВОДНЫЕ ДИАЗОКАРБАЗОЛА В КАЧЕСТВЕ ПЭТ-ЛИГАНДОВ БЕЛКА tau |
TWI667233B (zh) | 2013-12-19 | 2019-08-01 | 德商拜耳製藥公司 | 新穎吲唑羧醯胺,其製備方法、含彼等之醫藥製劑及其製造醫藥之用途 |
WO2015110263A1 (en) * | 2014-01-21 | 2015-07-30 | Ac Immune Sa | Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyolid-like proteins |
KR102530129B1 (ko) | 2014-05-13 | 2023-05-10 | 에프. 호프만-라 로슈 아게 | 중수소화된 헤테로사이클릭 화합물 및 이의 조영제로서의 용도 |
JP6782227B2 (ja) * | 2014-09-05 | 2020-11-11 | ザ・ジョンズ・ホプキンス・ユニバーシティー | CaMKII阻害剤及びその使用 |
WO2016037131A1 (en) | 2014-09-05 | 2016-03-10 | Symbiomix Therapeutics, Llc | Secnidazole for use in the treatment of bacterial vaginosis |
RS59707B1 (sr) | 2014-10-24 | 2020-01-31 | Bristol Myers Squibb Co | Derivati karbazola |
UY36371A (es) | 2014-10-24 | 2016-04-29 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Compuestos de indolcarboxamida inhibidores de quinasas tipo btk y tipo tec |
CN107108555B (zh) | 2014-10-24 | 2020-12-01 | 百时美施贵宝公司 | 三环阻转异构体化合物 |
MY191590A (en) * | 2015-02-02 | 2022-06-30 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
CN105566269B (zh) * | 2015-03-27 | 2018-07-10 | 北京大学 | 香豆素衍生物的制备、药理作用及治疗瘙痒的应用 |
CN105524034B (zh) * | 2015-03-27 | 2018-08-17 | 北京大学 | 香豆素衍生物的制备、药理作用及治疗脑缺血的应用 |
WO2016196653A1 (en) | 2015-06-01 | 2016-12-08 | Symbiomix Therapeutics, Llc | Novel nitroimidazole formulations and uses thereof |
WO2017009454A1 (en) | 2015-07-15 | 2017-01-19 | Ac Immune S.A. | Novel imaging compounds |
EP3118202A1 (en) | 2015-07-15 | 2017-01-18 | AC Immune S.A. | Dihydropyridopyrrole derivatives as tau-pet-ligands |
DK3374358T3 (da) | 2015-11-13 | 2021-03-08 | Lilly Co Eli | Azetidin-derivater til tau-billeddannelse |
AU2017216212B2 (en) * | 2016-02-03 | 2020-12-24 | Janssen Pharmaceutica Nv | Tau PET imaging ligands |
SG11201811311VA (en) * | 2016-07-22 | 2019-01-30 | Ac Immune Sa | Compounds for imaging tau protein aggregates |
JP7059270B2 (ja) | 2016-07-22 | 2022-04-25 | エーシー・イミューン・エス・アー | タウタンパク質凝集体を画像化するための化合物 |
WO2018024642A1 (en) | 2016-08-02 | 2018-02-08 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
WO2018024643A1 (en) | 2016-08-02 | 2018-02-08 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
EP3510031B1 (en) | 2016-09-09 | 2020-12-02 | H. Hoffnabb-La Roche Ag | Process for preparation of 2-(6-nitropyridin-3-yl)-9h-dipyrido[2,3-b;3',4'-d]pyrrole |
TW201906818A (zh) * | 2017-05-31 | 2019-02-16 | 美商511製藥公司 | 新穎氘取代之正子發射斷層掃描(pet)顯影劑及其藥理應用 |
EP3743423A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Gamma-carboline compounds for the detection of tau aggregates |
EP3743426A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Azacarboline compounds for the detection of tau aggregates |
WO2019168170A1 (ja) * | 2018-03-02 | 2019-09-06 | 国立大学法人 長崎大学 | クロモン誘導体及びアミロイド関連疾患診断用組成物 |
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EP4058065A4 (en) | 2019-11-13 | 2023-05-03 | Aprinoia Therapeutics Limited | COMPOUNDS FOR DEGRADING TAU PROTEIN AGGREGATES AND THEIR USES |
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WO2023034346A1 (en) * | 2021-08-30 | 2023-03-09 | Pretzel Therapeutics, Inc. | Chromen-2-one modulators of polrmt |
US11938127B2 (en) | 2021-09-28 | 2024-03-26 | Wayne State University | Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders |
TW202334089A (zh) | 2021-11-02 | 2023-09-01 | 美商夫雷爾醫療公司 | Pparg反向激動劑及其用途 |
WO2023204967A1 (en) * | 2022-04-21 | 2023-10-26 | Virginia Commonwealth University | Nlrp3 inflammasome inhibitors and compositions and uses thereof |
WO2024163546A1 (en) | 2023-02-02 | 2024-08-08 | Eli Lilly And Company | Novel compounds for tau imaging |
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SI2247558T2 (sl) | 2008-02-14 | 2024-10-30 | Eli Lilly And Company | Nova kontrastna sredstva za zaznavanje nevroloških disfunkcij |
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EA028483B1 (ru) | 2013-10-08 | 2017-11-30 | Ф. Хоффманн-Ля Рош Аг | ПРОИЗВОДНЫЕ ДИАЗОКАРБАЗОЛА В КАЧЕСТВЕ ПЭТ-ЛИГАНДОВ БЕЛКА tau |
MY191590A (en) | 2015-02-02 | 2022-06-30 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
-
2009
- 2009-02-17 SI SI200932157T patent/SI2247558T2/sl unknown
- 2009-02-17 PL PL09711194.2T patent/PL2247558T5/pl unknown
- 2009-02-17 PT PT97111942T patent/PT2247558T/pt unknown
- 2009-02-17 EP EP20130157487 patent/EP2599763A1/en not_active Withdrawn
- 2009-02-17 CA CA2715390A patent/CA2715390A1/en not_active Abandoned
- 2009-02-17 LT LTEPPCT/US2009/000961T patent/LT2247558T/lt unknown
- 2009-02-17 FI FIEP09711194.2T patent/FI2247558T4/fi active
- 2009-02-17 US US12/372,717 patent/US8318132B2/en active Active
- 2009-02-17 US US12/867,502 patent/US20110046378A1/en not_active Abandoned
- 2009-02-17 ES ES09711194T patent/ES2907992T3/es active Active
- 2009-02-17 EP EP09711194.2A patent/EP2247558B2/en active Active
- 2009-02-17 DK DK09711194.2T patent/DK2247558T4/da active
- 2009-02-17 HR HRP20220401TT patent/HRP20220401T4/hr unknown
- 2009-02-17 JP JP2010546795A patent/JP2011512354A/ja active Pending
- 2009-02-17 WO PCT/US2009/000961 patent/WO2009102498A1/en active Application Filing
- 2009-02-17 KR KR1020107020589A patent/KR20100135235A/ko not_active Application Discontinuation
- 2009-02-17 HU HUE09711194A patent/HUE058352T2/hu unknown
-
2022
- 2022-03-30 CY CY20221100245T patent/CY1125258T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HRP20220401T3 (hr) | 2022-05-27 |
ES2907992T3 (es) | 2022-04-27 |
US20110091382A1 (en) | 2011-04-21 |
SI2247558T1 (sl) | 2022-07-29 |
US8318132B2 (en) | 2012-11-27 |
CA2715390A1 (en) | 2009-08-20 |
PL2247558T3 (pl) | 2022-05-02 |
PL2247558T5 (pl) | 2024-10-14 |
LT2247558T (lt) | 2022-04-11 |
HRP20220401T4 (hr) | 2024-09-27 |
FI2247558T4 (fi) | 2024-09-19 |
JP2011512354A (ja) | 2011-04-21 |
DK2247558T4 (da) | 2024-07-29 |
EP2599763A1 (en) | 2013-06-05 |
CY1125258T1 (el) | 2024-02-16 |
EP2247558B2 (en) | 2024-07-03 |
US20110046378A1 (en) | 2011-02-24 |
EP2247558A1 (en) | 2010-11-10 |
EP2247558B1 (en) | 2022-02-02 |
DK2247558T3 (da) | 2022-02-21 |
KR20100135235A (ko) | 2010-12-24 |
WO2009102498A1 (en) | 2009-08-20 |
HUE058352T2 (hu) | 2022-07-28 |
PT2247558T (pt) | 2022-03-21 |
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