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SI1896016T1 - Postopek za solubilizacijo metronidazola - Google Patents

Postopek za solubilizacijo metronidazola

Info

Publication number
SI1896016T1
SI1896016T1 SI200630757T SI200630757T SI1896016T1 SI 1896016 T1 SI1896016 T1 SI 1896016T1 SI 200630757 T SI200630757 T SI 200630757T SI 200630757 T SI200630757 T SI 200630757T SI 1896016 T1 SI1896016 T1 SI 1896016T1
Authority
SI
Slovenia
Prior art keywords
metronidazole
glycolic
solution
aqueous
solubilizing
Prior art date
Application number
SI200630757T
Other languages
English (en)
Inventor
Claire Mallard
Alain Brzokewicz
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35597783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1896016(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of SI1896016T1 publication Critical patent/SI1896016T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
SI200630757T 2005-06-17 2006-06-16 Postopek za solubilizacijo metronidazola SI1896016T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0506182A FR2887149B1 (fr) 2005-06-17 2005-06-17 Procede de solubilisation du metronidazole
EP06778604A EP1896016B1 (fr) 2005-06-17 2006-06-16 Procede de solubilisation du metronidazole
PCT/FR2006/001367 WO2006134279A2 (fr) 2005-06-17 2006-06-16 Procede de solubilisation du metronidazole a l’aide de niacinamide et de deux glycols, solution ainsi obtenue

Publications (1)

Publication Number Publication Date
SI1896016T1 true SI1896016T1 (sl) 2010-10-29

Family

ID=35597783

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200630757T SI1896016T1 (sl) 2005-06-17 2006-06-16 Postopek za solubilizacijo metronidazola
SI200631390T SI2204174T1 (sl) 2005-06-17 2006-06-16 Postopek topljenja metronidazola z niacinamidom in dvema glikoloma in dobljena raztopina

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200631390T SI2204174T1 (sl) 2005-06-17 2006-06-16 Postopek topljenja metronidazola z niacinamidom in dvema glikoloma in dobljena raztopina

Country Status (13)

Country Link
US (3) US7981916B2 (sl)
EP (2) EP2204174B1 (sl)
AT (1) ATE476976T1 (sl)
CA (1) CA2611883A1 (sl)
CY (2) CY1110807T1 (sl)
DE (1) DE602006016122D1 (sl)
DK (2) DK2204174T3 (sl)
ES (2) ES2350368T3 (sl)
FR (1) FR2887149B1 (sl)
PL (2) PL2204174T3 (sl)
PT (2) PT1896016E (sl)
SI (2) SI1896016T1 (sl)
WO (1) WO2006134279A2 (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2887149B1 (fr) * 2005-06-17 2007-08-03 Galderma Sa Procede de solubilisation du metronidazole
GB0615016D0 (en) * 2006-07-28 2006-09-06 Flen Pharma N V Use of polyethylene glycol in inflammation related topical disorders or diseases and wound healing
WO2010047831A1 (en) * 2008-10-23 2010-04-29 Nycomed Us Inc. Stable metronidazole gel formulations
CN103763925A (zh) 2011-06-28 2014-04-30 梅迪奇制药有限公司 高剂量粘膜粘附甲硝唑水基凝胶制剂及其治疗细菌性阴道病的用途
CN110996908A (zh) 2017-08-11 2020-04-10 株式会社爱茉莉太平洋 包含(r)-n-[1-(3,5-二氟-4-甲磺酰氨基-苯基)-乙基]-3-(2-丙基-6-三氟甲基-吡啶-3-基)-丙烯酰胺的药物组合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032645A (en) * 1975-06-19 1977-06-28 G. D. Searle & Co. Injectable metronidazole composition
JPS5859913A (ja) * 1981-10-06 1983-04-09 Wakoudou Kk ジアゼパム注腸液
US4837378A (en) 1986-01-15 1989-06-06 Curatek Pharmaceuticals, Inc. Topical metronidazole formulations and therapeutic uses thereof
US5536743A (en) 1988-01-15 1996-07-16 Curatek Pharmaceuticals Limited Partnership Intravaginal treatment of vaginal infections with buffered metronidazole compositions
FR2722098B1 (fr) 1994-07-06 1996-08-23 Cird Galderma Nouveaux medicaments a base de metro-nidazole ou d'un melange synergetique de metronidazole et de clindamycine
US6444647B1 (en) * 1999-04-19 2002-09-03 The Procter & Gamble Company Skin care compositions containing combination of skin care actives
IN2000KO00299A (sl) * 1999-05-28 2005-11-18 Johnson & Johnson Consumer
US6468989B1 (en) 2000-07-13 2002-10-22 Dow Pharmaceutical Sciences Gel compositions containing metronidazole
US6387383B1 (en) * 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
WO2002094179A2 (en) * 2001-05-23 2002-11-28 J.B. Chemicals & Pharmaceuticals Ltd. Novel topical microbicidal compositions
US6881726B2 (en) * 2001-12-24 2005-04-19 Dow Pharmaceutical Sciences Aqueous compositions containing metronidazole
KR100773537B1 (ko) * 2003-06-03 2007-11-07 삼성전자주식회사 한 개의 스위칭 소자와 한 개의 저항체를 포함하는비휘발성 메모리 장치 및 그 제조 방법
FR2887149B1 (fr) * 2005-06-17 2007-08-03 Galderma Sa Procede de solubilisation du metronidazole
KR100626381B1 (ko) * 2004-07-19 2006-09-20 삼성전자주식회사 상변화 기억 소자 및 그 형성 방법

Also Published As

Publication number Publication date
WO2006134279A2 (fr) 2006-12-21
DE602006016122D1 (de) 2010-09-23
EP1896016A2 (fr) 2008-03-12
FR2887149A1 (fr) 2006-12-22
CY1110807T1 (el) 2015-06-10
PT2204174E (pt) 2012-08-09
US20080161375A1 (en) 2008-07-03
ES2388236T3 (es) 2012-10-11
DK2204174T3 (da) 2012-08-27
US7981916B2 (en) 2011-07-19
WO2006134279A3 (fr) 2007-02-22
CA2611883A1 (fr) 2006-12-21
ES2350368T3 (es) 2011-01-21
US20100048645A1 (en) 2010-02-25
CY1113401T1 (el) 2016-06-22
SI2204174T1 (sl) 2012-10-30
EP2204174B1 (fr) 2012-05-16
EP1896016B1 (fr) 2010-08-11
PL1896016T3 (pl) 2011-05-31
DK1896016T3 (da) 2010-11-22
US8859603B2 (en) 2014-10-14
EP2204174A1 (fr) 2010-07-07
PL2204174T3 (pl) 2012-10-31
PT1896016E (pt) 2010-11-04
ATE476976T1 (de) 2010-08-15
FR2887149B1 (fr) 2007-08-03
US20110217357A1 (en) 2011-09-08

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