[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

SI1192134T1 - Processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4 piperidinemethanol - Google Patents

Processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4 piperidinemethanol

Info

Publication number
SI1192134T1
SI1192134T1 SI9930992T SI9930992T SI1192134T1 SI 1192134 T1 SI1192134 T1 SI 1192134T1 SI 9930992 T SI9930992 T SI 9930992T SI 9930992 T SI9930992 T SI 9930992T SI 1192134 T1 SI1192134 T1 SI 1192134T1
Authority
SI
Slovenia
Prior art keywords
piperidinemethanol
dimethoxyphenyl
fluorophenyl
alpha
ethyl
Prior art date
Application number
SI9930992T
Other languages
Slovenian (sl)
Inventor
Alan G Bina
Edward D Daugs
Jonathan C Evans
Hans-Wolfram Flemming
Gerard Guillamot
Robert A Hawtorne
Thomas H E Hilpert
James E Hitt
Chi-Hsin R King
Johannes N Koek
Frederick M Laskovics
John M Lefler
Alexey L Margolin
Sharon K Minish
Thomas T Ortyl
Lian G Rajewski
Marvin J Sack
Paul F Skultety
Sandra K Stoltz-Dunn
Alonzo L Tigner
Ian A Tomlinson
Original Assignee
Aventis Pharma Inc
Hoechst Marion Roussel De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc, Hoechst Marion Roussel De Gmbh filed Critical Aventis Pharma Inc
Priority claimed from EP99911318A external-priority patent/EP1192134B1/en
Publication of SI1192134T1 publication Critical patent/SI1192134T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
SI9930992T 1998-03-13 1999-03-11 Processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4 piperidinemethanol SI1192134T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4225198A 1998-03-13 1998-03-13
US25071899A 1999-02-16 1999-02-16
EP99911318A EP1192134B1 (en) 1998-03-13 1999-03-11 Processes for the preparation of (r)-g(a)-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol
PCT/US1999/005332 WO1999046245A2 (en) 1998-03-13 1999-03-11 PROCESSES FOR THE PREPARATION OF (R)-α- (2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL

Publications (1)

Publication Number Publication Date
SI1192134T1 true SI1192134T1 (en) 2008-02-29

Family

ID=37398590

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930992T SI1192134T1 (en) 1998-03-13 1999-03-11 Processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4 piperidinemethanol

Country Status (1)

Country Link
SI (1) SI1192134T1 (en)

Similar Documents

Publication Publication Date Title
AU2001247474A1 (en) Compounds for the treatment of psychiatric or substance abuse disorders
IL175983A0 (en) Processes and intermediates for the preparation of (r) -??-(2,3 - dimethoxyphenyl) - 1 - [2 - (4-fluorophenyl) ethyl] - 4 - piperidine methanol
PL344390A1 (en) Method of obtaining derivatives of 1,4-dihydropyridine
PT1289527E (en) (+)-alpha-(2,3-dimethoxyphenyl)-1(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol or its prodrug to treat dementia or cognitive impairment
AU1987400A (en) Process for preparation of paroxetine maleate
AU1788800A (en) Derivative of paroxetine
PL344994A1 (en) Derivatives of 3-(2-oxo-[1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems
AU1018801A (en) Use of 3,4-substituted piperidines
IL155706A0 (en) Process for the preparation of (r)-5-(2-benzenesulfonylethyl)-3-(n-methylpyrrolidin-2-ylmethyl)-1h-indole
HUP0002709A3 (en) Process for the reduction of 1-substituted -3-hydroxymethyl-4- (4-fluorophenyl)tetrahydropyridines
AU1037901A (en) Process for the preparation of paroxetine
AU3818900A (en) Process for the preparation of substituted piperidines
IL129647A0 (en) Substituted 4-(6-fluoro-(1H)-indol-3-YL)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders
SI1192134T1 (en) Processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4 piperidinemethanol
AU5553200A (en) Process for the preparation of paroxetine and structurally related compounds
HUP0004503A3 (en) Process for the preparation of paroxetine hydrochloride
IL147830A0 (en) Process for the preparation of acylated 1,3-dicarbonyl compounds
AU6010099A (en) Process for the preparation of an n-alkyl or n-aryl carbamoyl derivative
AU6481799A (en) Process for the preparation of paroxetine hydrochloride
AU1396400A (en) Process for the preparation of paroxetine hydrochloride
PL347318A1 (en) Esters of (+)-alpha-( 2,3- dimethoxyphenyl) -1-[2-(4- fluorophenyl) ethyl]-4- piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
ZA991907B (en) Novel processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol.
HUP0202145A3 (en) The use of r(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol for the treatment of sleep disorders
AU6875800A (en) Heterocyclic compounds and process for the preparation thereof
ZA989842B (en) Esters of (+)-Ó-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol.