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SG52444A1 - Chemical process - Google Patents

Chemical process

Info

Publication number
SG52444A1
SG52444A1 SG1996004614A SG1996004614A SG52444A1 SG 52444 A1 SG52444 A1 SG 52444A1 SG 1996004614 A SG1996004614 A SG 1996004614A SG 1996004614 A SG1996004614 A SG 1996004614A SG 52444 A1 SG52444 A1 SG 52444A1
Authority
SG
Singapore
Prior art keywords
chemical process
chem
compound
formula
preparation
Prior art date
Application number
SG1996004614A
Other languages
English (en)
Inventor
Andrew Jonathan Whitebread
David William Stuart Latham
Michael David Goodyear
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SG52444A1 publication Critical patent/SG52444A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
SG1996004614A 1993-08-13 1994-08-11 Chemical process SG52444A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939316863A GB9316863D0 (en) 1993-08-13 1993-08-13 Chemical process

Publications (1)

Publication Number Publication Date
SG52444A1 true SG52444A1 (en) 1998-09-28

Family

ID=10740452

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996004614A SG52444A1 (en) 1993-08-13 1994-08-11 Chemical process

Country Status (10)

Country Link
US (1) US5599938A (de)
EP (1) EP0638554B1 (de)
JP (1) JP3429370B2 (de)
AT (1) ATE159519T1 (de)
DE (1) DE69406382T2 (de)
DK (1) DK0638554T3 (de)
ES (1) ES2109595T3 (de)
GB (1) GB9316863D0 (de)
GR (1) GR3025213T3 (de)
SG (1) SG52444A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866591A (en) * 1996-09-11 1999-02-02 Glaxo Wellcome Inc. Stable formulations of remifentanil
US20080319196A1 (en) * 2005-11-17 2008-12-25 Cheng Brian K Process for Synthesizing Remifentanil
US20080312448A1 (en) * 2006-01-24 2008-12-18 Cheng Brian K Process for Synthesizing Remifentanil
PL3199523T3 (pl) 2016-01-29 2019-03-29 Bioka s. r.o. Nowa procedura do produkcji n-fenylo-n-(4- piperydynylo) pochodnych amidowych, jakimi jest na przykład remifentanyl i karfentanyl

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179569A (en) * 1975-03-14 1979-12-18 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-N-phenylamides
US3998834A (en) * 1975-03-14 1976-12-21 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-n-phenylamides and -carbamates
US4584303A (en) * 1984-04-09 1986-04-22 The Boc Group, Inc. N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds
US5019583A (en) * 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics

Also Published As

Publication number Publication date
ES2109595T3 (es) 1998-01-16
US5599938A (en) 1997-02-04
EP0638554B1 (de) 1997-10-22
JPH07165713A (ja) 1995-06-27
DE69406382D1 (de) 1997-11-27
DE69406382T2 (de) 1998-02-26
ATE159519T1 (de) 1997-11-15
GR3025213T3 (en) 1998-02-27
GB9316863D0 (en) 1993-09-29
JP3429370B2 (ja) 2003-07-22
EP0638554A1 (de) 1995-02-15
DK0638554T3 (da) 1998-02-09

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