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SG177028A1 - Method and apparatus relating to fluorescence imaging and point-wise spectroscopy for in vivo tissue measurements at endoscopy - Google Patents

Method and apparatus relating to fluorescence imaging and point-wise spectroscopy for in vivo tissue measurements at endoscopy Download PDF

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Publication number
SG177028A1
SG177028A1 SG2010045672A SG2010045672A SG177028A1 SG 177028 A1 SG177028 A1 SG 177028A1 SG 2010045672 A SG2010045672 A SG 2010045672A SG 2010045672 A SG2010045672 A SG 2010045672A SG 177028 A1 SG177028 A1 SG 177028A1
Authority
SG
Singapore
Prior art keywords
point
wise
spectroscopy
endoscopy
apparatus relating
Prior art date
Application number
SG2010045672A
Inventor
Zhiwei Huang
Original Assignee
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore filed Critical Univ Singapore
Priority to SG2010045672A priority Critical patent/SG177028A1/en
Priority to PCT/SG2011/000218 priority patent/WO2011162721A1/en
Publication of SG177028A1 publication Critical patent/SG177028A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/042—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by a proximal camera, e.g. a CCD camera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Endoscopes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

Method and Apparatus Relating to Fluorescence imaging and point-wiseSpectroscopy for in vivo Tissue Measurements at EndoscopyAbstract. We report on the development of an nifegated point-wise spectroscopy andautofluorescence (AF) endoscopic imaging technique for real-time in vivo tissuemeasurements at endoscopy We implement a unique optical design to realize real-bine AFunaging and AF/ ,or e (DE spectroscopy ineasuretnents from a sinall area(100[err]m in diameter) of fissue of interest on the AF image- We denionstratr that, both theAF iniage and the point-wise i AFIDR spectra can he sinniltmeously acquired from the oralcavity in -viva within 01 second, and significant dianges AF imaging and point-wise AFspectroscopy can be observed in cancerous colonic and head and neck tissues- This workdemonstrates the potential. of applying ' the integrated spectroscopytechnique developed to facilitate in viva tissue diagnosis and charicterizatton at endowmpyFigure 1.
SG2010045672A 2010-06-25 2010-06-25 Method and apparatus relating to fluorescence imaging and point-wise spectroscopy for in vivo tissue measurements at endoscopy SG177028A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SG2010045672A SG177028A1 (en) 2010-06-25 2010-06-25 Method and apparatus relating to fluorescence imaging and point-wise spectroscopy for in vivo tissue measurements at endoscopy
PCT/SG2011/000218 WO2011162721A1 (en) 2010-06-25 2011-06-21 Method and system for performing tissue measurements

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG2010045672A SG177028A1 (en) 2010-06-25 2010-06-25 Method and apparatus relating to fluorescence imaging and point-wise spectroscopy for in vivo tissue measurements at endoscopy

Publications (1)

Publication Number Publication Date
SG177028A1 true SG177028A1 (en) 2012-01-30

Family

ID=45371687

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2010045672A SG177028A1 (en) 2010-06-25 2010-06-25 Method and apparatus relating to fluorescence imaging and point-wise spectroscopy for in vivo tissue measurements at endoscopy

Country Status (2)

Country Link
SG (1) SG177028A1 (en)
WO (1) WO2011162721A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102015102595B4 (en) * 2015-02-24 2021-01-28 Karl Storz Se & Co. Kg Optical observation arrangement, camera, endoscope or exoscope and endoscope or exoscope system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3417795B2 (en) * 1997-04-30 2003-06-16 ペンタックス株式会社 Fluorescence diagnostic equipment
US6826424B1 (en) * 2000-12-19 2004-11-30 Haishan Zeng Methods and apparatus for fluorescence and reflectance imaging and spectroscopy and for contemporaneous measurements of electromagnetic radiation with multiple measuring devices
US20050027166A1 (en) * 2003-06-17 2005-02-03 Shinya Matsumoto Endoscope system for fluorescent observation

Also Published As

Publication number Publication date
WO2011162721A1 (en) 2011-12-29

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