SG141218A1 - Method for prediction of single nucleotide polymorphisms - Google Patents
Method for prediction of single nucleotide polymorphismsInfo
- Publication number
- SG141218A1 SG141218A1 SG200305888-0A SG2003058880A SG141218A1 SG 141218 A1 SG141218 A1 SG 141218A1 SG 2003058880 A SG2003058880 A SG 2003058880A SG 141218 A1 SG141218 A1 SG 141218A1
- Authority
- SG
- Singapore
- Prior art keywords
- negative
- positive
- snps
- parameters
- information
- Prior art date
Links
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
METHOD FOR PREDICTION OF SINGLE NUCLEOTIDE POLYMORPHISMS There are disclosed methods that utilize learning machine algorithms for predicting of single nucleotide polymorphisms in polynucleotide sequences. The methods comprise steps of:generating training sets of positive and negative SNPs; calculating one or more parameters of each member of the training sets of positive and negative SNPs; training a learning machine algorithm with the one or more parameters of members of the training sets of positive and negative SNPs; and testing the trained learning machine algorithm with test sets of positive and negative SNPs; thereby the best prediction results are recorded by using any of the one or more parameters. The parameters of positive and negative SNPs used for the learning machine algorithms include free energy change ([err]G), entropy ([err]S),enthalpy ([err]H), melting temperature, GC content, SNP distribution score information, sequence information, gene information, intron information and exon information; wherein each parameter is calculated by its own rules. No figure included
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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SG200305888-0A SG141218A1 (en) | 2003-10-07 | 2003-10-07 | Method for prediction of single nucleotide polymorphisms |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG200305888-0A SG141218A1 (en) | 2003-10-07 | 2003-10-07 | Method for prediction of single nucleotide polymorphisms |
Publications (1)
Publication Number | Publication Date |
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SG141218A1 true SG141218A1 (en) | 2008-04-28 |
Family
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Family Applications (1)
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SG200305888-0A SG141218A1 (en) | 2003-10-07 | 2003-10-07 | Method for prediction of single nucleotide polymorphisms |
Country Status (1)
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SG (1) | SG141218A1 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103675011A (en) * | 2013-09-22 | 2014-03-26 | 浙江大学 | Soft industrial melt index measurement instrument and method of optimal support vector machine |
CN109490702A (en) * | 2018-10-08 | 2019-03-19 | 西南交通大学 | A kind of method for diagnosing faults based on adaptive optimization pulse nerve membranous system |
CN110084399A (en) * | 2019-03-21 | 2019-08-02 | 山东省疾病预防控制中心 | A kind of periodical Time Series Forecasting Methods based on support vector machines |
CN112992268A (en) * | 2021-03-03 | 2021-06-18 | 兰州蓝鲸信息技术有限公司 | SNP locus sequence feature extraction method |
CN114530200A (en) * | 2022-03-18 | 2022-05-24 | 北京阅微基因技术股份有限公司 | Mixed sample identification method based on calculation of SNP entropy |
CN117253539A (en) * | 2023-11-20 | 2023-12-19 | 北京求臻医学检验实验室有限公司 | Method and system for detecting sample pollution in high-throughput sequencing based on germ line mutation |
-
2003
- 2003-10-07 SG SG200305888-0A patent/SG141218A1/en unknown
Non-Patent Citations (1)
Title |
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ANALYSIS OF MULTIPLE SINGLE NUCLEOTIDE POLYMORPHISMS OF CANDIDATE GENES RELATED TO CORONARY HEART DISEASE SUSCEPTIBILITY BY USING SUPPORT VEC TOR MACHINES., ARTIFICIAL NEURAL NETWORK PREDICTIVE MODEL FOR ALLERGIC * |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103675011A (en) * | 2013-09-22 | 2014-03-26 | 浙江大学 | Soft industrial melt index measurement instrument and method of optimal support vector machine |
CN109490702A (en) * | 2018-10-08 | 2019-03-19 | 西南交通大学 | A kind of method for diagnosing faults based on adaptive optimization pulse nerve membranous system |
CN109490702B (en) * | 2018-10-08 | 2019-11-05 | 西南交通大学 | A kind of method for diagnosing faults based on adaptive optimization pulse nerve membranous system |
CN110084399A (en) * | 2019-03-21 | 2019-08-02 | 山东省疾病预防控制中心 | A kind of periodical Time Series Forecasting Methods based on support vector machines |
CN110084399B (en) * | 2019-03-21 | 2023-04-07 | 山东省疾病预防控制中心 | Periodic time sequence prediction method based on support vector machine |
CN112992268A (en) * | 2021-03-03 | 2021-06-18 | 兰州蓝鲸信息技术有限公司 | SNP locus sequence feature extraction method |
CN114530200A (en) * | 2022-03-18 | 2022-05-24 | 北京阅微基因技术股份有限公司 | Mixed sample identification method based on calculation of SNP entropy |
CN117253539A (en) * | 2023-11-20 | 2023-12-19 | 北京求臻医学检验实验室有限公司 | Method and system for detecting sample pollution in high-throughput sequencing based on germ line mutation |
CN117253539B (en) * | 2023-11-20 | 2024-02-06 | 北京求臻医学检验实验室有限公司 | Method and system for detecting sample pollution in high-throughput sequencing based on germ line mutation |
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