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SG11202102847TA - Isoxazole carboxamide compounds and uses thereof - Google Patents

Isoxazole carboxamide compounds and uses thereof

Info

Publication number
SG11202102847TA
SG11202102847TA SG11202102847TA SG11202102847TA SG11202102847TA SG 11202102847T A SG11202102847T A SG 11202102847TA SG 11202102847T A SG11202102847T A SG 11202102847TA SG 11202102847T A SG11202102847T A SG 11202102847TA SG 11202102847T A SG11202102847T A SG 11202102847TA
Authority
SG
Singapore
Prior art keywords
carboxamide compounds
isoxazole carboxamide
isoxazole
compounds
carboxamide
Prior art date
Application number
SG11202102847TA
Inventor
Rohan Eric John Beckwith
Hua Jiang
Ce Wang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SG11202102847TA publication Critical patent/SG11202102847TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202102847TA 2018-09-21 2019-09-19 Isoxazole carboxamide compounds and uses thereof SG11202102847TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2018106939 2018-09-21
PCT/IB2019/057941 WO2020058913A1 (en) 2018-09-21 2019-09-19 Isoxazole carboxamide compounds and uses thereof

Publications (1)

Publication Number Publication Date
SG11202102847TA true SG11202102847TA (en) 2021-04-29

Family

ID=68062995

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102847TA SG11202102847TA (en) 2018-09-21 2019-09-19 Isoxazole carboxamide compounds and uses thereof

Country Status (22)

Country Link
US (1) US20210355115A1 (en)
EP (1) EP3853212A1 (en)
JP (1) JP2022501366A (en)
KR (1) KR20210066848A (en)
CN (1) CN113056455A (en)
AU (1) AU2019341709A1 (en)
BR (1) BR112021005263A2 (en)
CA (1) CA3113573A1 (en)
CL (1) CL2021000706A1 (en)
CO (1) CO2021003714A2 (en)
CR (1) CR20210148A (en)
CU (1) CU20210018A7 (en)
DO (1) DOP2021000046A (en)
EC (1) ECSP21020602A (en)
IL (1) IL281662A (en)
JO (1) JOP20210053A1 (en)
MA (1) MA53645A (en)
MX (1) MX2021003294A (en)
PE (1) PE20211071A1 (en)
PH (1) PH12021550646A1 (en)
SG (1) SG11202102847TA (en)
WO (1) WO2020058913A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3219597A1 (en) * 2021-06-23 2022-12-29 F. Hoffmann-La Roche Ag Novel process
CN114315609B (en) * 2022-01-15 2024-01-30 大连双硼医药化工有限公司 Technological method for preparing cis-2-aminocyclohexanol

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5421818A (en) 1993-10-18 1995-06-06 Inner Ear Medical Delivery Systems, Inc. Multi-functional inner ear treatment and diagnostic system
JP2007524596A (en) 2003-02-28 2007-08-30 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド Co-crystal pharmaceutical composition
WO2005115527A2 (en) 2004-05-24 2005-12-08 Auris Medical, Llc. Combined otic aspirator and medication dispenser
AU2014302458A1 (en) * 2013-06-26 2015-12-24 Proteostasis Therapeutics, Inc. Methods of modulating CFTR activity
CA2960274A1 (en) * 2014-09-10 2016-03-17 Epizyme, Inc. Isoxazole carboxamide compounds
TWI625332B (en) * 2015-07-07 2018-06-01 美國禮來大藥廠 Notch pathway signaling inhibitor compounds
AU2018237987B2 (en) * 2017-03-24 2021-01-21 Novartis Ag Isoxazole carboxamide compounds and uses thereof

Also Published As

Publication number Publication date
US20210355115A1 (en) 2021-11-18
PH12021550646A1 (en) 2021-10-11
EP3853212A1 (en) 2021-07-28
CA3113573A1 (en) 2020-03-26
WO2020058913A1 (en) 2020-03-26
IL281662A (en) 2021-05-31
ECSP21020602A (en) 2021-04-29
BR112021005263A2 (en) 2021-06-15
CO2021003714A2 (en) 2021-04-08
KR20210066848A (en) 2021-06-07
MX2021003294A (en) 2021-07-15
CL2021000706A1 (en) 2021-10-22
JP2022501366A (en) 2022-01-06
CR20210148A (en) 2021-05-18
DOP2021000046A (en) 2021-05-31
CN113056455A (en) 2021-06-29
AU2019341709A1 (en) 2021-04-15
CU20210018A7 (en) 2021-10-12
PE20211071A1 (en) 2021-06-09
MA53645A (en) 2021-12-29
JOP20210053A1 (en) 2021-03-21

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