SG11202012619WA - Methods for improving response to anti-lif antibody treatment in individuals with cancer - Google Patents
Methods for improving response to anti-lif antibody treatment in individuals with cancerInfo
- Publication number
- SG11202012619WA SG11202012619WA SG11202012619WA SG11202012619WA SG11202012619WA SG 11202012619W A SG11202012619W A SG 11202012619WA SG 11202012619W A SG11202012619W A SG 11202012619WA SG 11202012619W A SG11202012619W A SG 11202012619WA SG 11202012619W A SG11202012619W A SG 11202012619WA
- Authority
- SG
- Singapore
- Prior art keywords
- individuals
- cancer
- methods
- antibody treatment
- improving response
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18382431 | 2018-06-18 | ||
EP19382131 | 2019-02-22 | ||
PCT/IB2019/000806 WO2019243898A2 (en) | 2018-06-18 | 2019-06-17 | Methods for improving response to anti-lif antibody treatment in individuals with cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202012619WA true SG11202012619WA (en) | 2021-01-28 |
Family
ID=68136437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202012619WA SG11202012619WA (en) | 2018-06-18 | 2019-06-17 | Methods for improving response to anti-lif antibody treatment in individuals with cancer |
Country Status (11)
Country | Link |
---|---|
US (1) | US20210253691A1 (en) |
EP (1) | EP3807315A2 (en) |
JP (1) | JP7520727B2 (en) |
KR (1) | KR20210024007A (en) |
CN (1) | CN112703202A (en) |
AU (1) | AU2019291305B2 (en) |
CA (1) | CA3103763A1 (en) |
IL (1) | IL279484A (en) |
MA (1) | MA52299A (en) |
SG (1) | SG11202012619WA (en) |
WO (1) | WO2019243898A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102599557B1 (en) * | 2016-12-19 | 2023-11-07 | 펀다시오 프리바다 인스티튜시오 카탈라나 드 르세르카 아이 에스투디스 아반카츠 | Antibodies to LIF and their uses |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2363358B1 (en) | 2009-04-03 | 2012-06-21 | FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al | THERAPEUTIC AGENTS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AN INDESEABLE CELLULAR PROLIFERATION. |
EP2371860A1 (en) | 2010-04-05 | 2011-10-05 | Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron | Antibody recognising human leukemia inhibitory factor (LIF) and use of anti-LIF antibodies in the treatment of diseases associated with unwanted cell proliferation |
EP3173483A1 (en) * | 2015-11-27 | 2017-05-31 | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron | Agents for the treatment of diseases associated with undesired cell proliferation |
EP3490542A4 (en) * | 2016-07-26 | 2020-07-08 | Flagship Pioneering Innovations V, Inc. | Neuromodulating compositions and related therapeutic methods for the treatment of cancer by modulating an anti-cancer immune response |
WO2018115960A1 (en) * | 2016-12-19 | 2018-06-28 | Mosaic Biomedicals, S.L. | Antibodies against lif and uses thereof |
-
2019
- 2019-06-17 US US17/252,482 patent/US20210253691A1/en active Pending
- 2019-06-17 CA CA3103763A patent/CA3103763A1/en active Pending
- 2019-06-17 KR KR1020217001445A patent/KR20210024007A/en unknown
- 2019-06-17 EP EP19782686.0A patent/EP3807315A2/en active Pending
- 2019-06-17 SG SG11202012619WA patent/SG11202012619WA/en unknown
- 2019-06-17 CN CN201980053677.2A patent/CN112703202A/en active Pending
- 2019-06-17 MA MA052299A patent/MA52299A/en unknown
- 2019-06-17 WO PCT/IB2019/000806 patent/WO2019243898A2/en unknown
- 2019-06-17 JP JP2020570177A patent/JP7520727B2/en active Active
- 2019-06-17 AU AU2019291305A patent/AU2019291305B2/en active Active
-
2020
- 2020-12-16 IL IL279484A patent/IL279484A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2019243898A3 (en) | 2020-02-13 |
MA52299A (en) | 2021-04-21 |
WO2019243898A2 (en) | 2019-12-26 |
IL279484A (en) | 2021-01-31 |
CA3103763A1 (en) | 2019-12-26 |
AU2019291305A1 (en) | 2021-01-28 |
JP2021529162A (en) | 2021-10-28 |
EP3807315A2 (en) | 2021-04-21 |
US20210253691A1 (en) | 2021-08-19 |
JP7520727B2 (en) | 2024-07-23 |
AU2019291305B2 (en) | 2024-03-21 |
KR20210024007A (en) | 2021-03-04 |
WO2019243898A8 (en) | 2020-09-24 |
CN112703202A (en) | 2021-04-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1243005A1 (en) | Anti-lilrb antibodies and their use in detecting and treating cancer | |
IL256687B (en) | Isolated tau-binding antibody and use thereof in therapy and diagnosis | |
NZ739750A (en) | Anti-tigit antibodies and methods of use | |
GEP20227343B (en) | Anti-lag3 antibodies and antigen-binding fragments | |
HUE065528T2 (en) | Combination of zanubrutinib with an anti-cd20 or an anti-pd-1 antibody for use in treating cancer | |
MX2021002728A (en) | Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors. | |
MX2015013166A (en) | Dual specific binding proteins directed against il-1 beta and il-17. | |
SG11201507563SA (en) | Cancer treatment using antibodies that bind cell surface grp78 | |
IL248511A0 (en) | Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and a monoclonal antibody against tim-3 | |
EP3303402A4 (en) | Antibodies against glypican-3 and their uses in cancer diagnosis and treatment | |
SG10202112636SA (en) | Anti-fgfr2 antibodies in combination with chemotherapy agents in cancer treatment | |
IL258980A (en) | Bi-specific antibodies, their preparation and their use in cancer | |
ZA202000851B (en) | Antibodies useful in cancer diagnosis | |
IL255314A0 (en) | Anti-ap2 antibodies and antigen binding agents to treat metabolic disorders | |
ZA202204422B (en) | Methods of cancer treatment using anti-ox40 antibodies in combination with anti-tigit antibodies | |
WO2015153997A3 (en) | Notch3 antibodies and uses thereof | |
SG11202005296SA (en) | Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer | |
SG11202000634UA (en) | Antibodies to m(h)dm2/4 and their use in diagnosing and treating cancer | |
SG11202101395XA (en) | Conjugates for use in methods of treating cancer | |
PT3144676T (en) | Kit comprising antibody specifically binding to complement factor b protein and antibody specifically binding to carbohydrate antigen 19-9 protein for diagnosing pancreatic cancer | |
EP3240566A4 (en) | Humanized alpha-enolase specific antibodies and methods of uses in cancer therapy | |
IL279484A (en) | Methods for improving response to anti-lif antibody treatment in individuals with cancer | |
MX2015015232A (en) | Monoclonal antibody directed against cxcr5. | |
ZA202204252B (en) | Methods of cancer treatment using anti-ox40 antibodies in combination with anti-tim3 antibodies | |
IL280421A (en) | Cancer treatment with an antibody |