SG11202005502PA - Inertial cell focusing and sorting - Google Patents
Inertial cell focusing and sortingInfo
- Publication number
- SG11202005502PA SG11202005502PA SG11202005502PA SG11202005502PA SG11202005502PA SG 11202005502P A SG11202005502P A SG 11202005502PA SG 11202005502P A SG11202005502P A SG 11202005502PA SG 11202005502P A SG11202005502P A SG 11202005502PA SG 11202005502P A SG11202005502P A SG 11202005502PA
- Authority
- SG
- Singapore
- Prior art keywords
- sorting
- cell focusing
- inertial
- inertial cell
- focusing
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0255—Investigating particle size or size distribution with mechanical, e.g. inertial, classification, and investigation of sorted collections
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0463—Hydrodynamic forces, venturi nozzles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Fluid Mechanics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG10201710457X | 2017-12-15 | ||
PCT/SG2018/050615 WO2019117815A1 (en) | 2017-12-15 | 2018-12-14 | Inertial cell focusing and sorting |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202005502PA true SG11202005502PA (en) | 2020-07-29 |
Family
ID=66819028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202005502PA SG11202005502PA (en) | 2017-12-15 | 2018-12-14 | Inertial cell focusing and sorting |
Country Status (6)
Country | Link |
---|---|
US (1) | US20210053061A1 (en) |
EP (1) | EP3723906A4 (en) |
JP (1) | JP2021506263A (en) |
CN (1) | CN111491736B (en) |
SG (1) | SG11202005502PA (en) |
WO (1) | WO2019117815A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113769797B (en) * | 2021-09-02 | 2023-03-14 | 浙江理工大学 | Method for measuring diameter of micro-scale particles in fluid-solid two-phase transportation |
CN114700126B (en) * | 2022-05-06 | 2024-03-19 | 季华实验室 | Microfluidic sorting chip |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7160025B2 (en) * | 2003-06-11 | 2007-01-09 | Agency For Science, Technology And Research | Micromixer apparatus and methods of using same |
US20070263477A1 (en) * | 2006-05-11 | 2007-11-15 | The Texas A&M University System | Method for mixing fluids in microfluidic channels |
US10052571B2 (en) * | 2007-11-07 | 2018-08-21 | Palo Alto Research Center Incorporated | Fluidic device and method for separation of neutrally buoyant particles |
EP2482055A3 (en) * | 2007-04-16 | 2013-10-30 | The General Hospital Corporation d/b/a Massachusetts General Hospital | Systems and methods for particle focusing in microchannels |
WO2008134363A1 (en) * | 2007-04-25 | 2008-11-06 | The Regents Of The University Of Michigan | Tunable elastomeric nanochannels for nanofluidic manipulation |
US7999937B1 (en) * | 2008-05-13 | 2011-08-16 | Sandia Corporation | Microfluidic devices and methods for integrated flow cytometry |
US20120270331A1 (en) * | 2011-04-20 | 2012-10-25 | Achal Singh Achrol | Microfluidic system and method for automated processing of particles from biological fluid |
US10144009B2 (en) * | 2013-10-16 | 2018-12-04 | Clearbridge Biomedics Pte Ltd | Microfluidics sorter for cell detection and isolation |
US9782770B2 (en) * | 2014-06-06 | 2017-10-10 | Illumina, Inc. | Systems and methods of loading or removing liquids used in biochemical analysis |
CN104111190B (en) * | 2014-07-18 | 2016-09-28 | 国家纳米科学中心 | A kind of Double helix micro-fluidic chip |
KR101636316B1 (en) * | 2014-09-22 | 2016-07-05 | 연세대학교 산학협력단 | Microfluidic apparatus for isolation, method for isolation using the same, and isolation kit for circulating rare cells using the same |
CN105486571A (en) * | 2015-11-09 | 2016-04-13 | 上海海洋大学 | Microfluidic chip used for enriching microbial aerosol and preparation method thereof |
-
2018
- 2018-12-14 WO PCT/SG2018/050615 patent/WO2019117815A1/en unknown
- 2018-12-14 JP JP2020532708A patent/JP2021506263A/en active Pending
- 2018-12-14 CN CN201880081020.2A patent/CN111491736B/en active Active
- 2018-12-14 US US16/772,991 patent/US20210053061A1/en not_active Abandoned
- 2018-12-14 SG SG11202005502PA patent/SG11202005502PA/en unknown
- 2018-12-14 EP EP18887445.7A patent/EP3723906A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP3723906A1 (en) | 2020-10-21 |
CN111491736B (en) | 2022-11-15 |
JP2021506263A (en) | 2021-02-22 |
CN111491736A (en) | 2020-08-04 |
WO2019117815A1 (en) | 2019-06-20 |
EP3723906A4 (en) | 2021-08-25 |
US20210053061A1 (en) | 2021-02-25 |
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