SG11201811246RA - Novel silybum marianum achene extract and uses thereof in dermatology and dermo-cosmetics - Google Patents
Novel silybum marianum achene extract and uses thereof in dermatology and dermo-cosmeticsInfo
- Publication number
- SG11201811246RA SG11201811246RA SG11201811246RA SG11201811246RA SG11201811246RA SG 11201811246R A SG11201811246R A SG 11201811246RA SG 11201811246R A SG11201811246R A SG 11201811246RA SG 11201811246R A SG11201811246R A SG 11201811246RA SG 11201811246R A SG11201811246R A SG 11201811246RA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- extract
- pct
- silybum marianum
- dermatology
- Prior art date
Links
- 244000272459 Silybum marianum Species 0.000 title abstract 3
- 235000010841 Silybum marianum Nutrition 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 102220240796 rs553605556 Human genes 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 241001303601 Rosacea Species 0.000 abstract 1
- 206010039792 Seborrhoea Diseases 0.000 abstract 1
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 201000004700 rosacea Diseases 0.000 abstract 1
- 208000008742 seborrheic dermatitis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Birds (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 January 2018 (04.01.2018) W I PO I PCT omits I iolo 0111011010111011 OM 10 EMO 011 (10) International Publication Number WO 2018/002338 Al (51) International Patent Classification: A61K 36/28 (2006.01) A61P 17/10 (2006.01) A61P 17/08 (2006.01) (21) International Application Number: Published: — with international search report (Art. 21(3)) PCT/EP2017/066349 (22) International Filing Date: 30 June 2017 (30.06.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1656328 01 July 2016 (01.07.2016) FR (71) Applicant: PIERRE FABRE DERMO-COSMETIQUE [FR/FR]; 45, place Abel Gance, 92100 BOULOGNE-BIL- LANCOURT (FR). (72) Inventors: SAURAT, Jean-Hilaire; 2 Place Reverdin, 1206 GENEVE (CH). SORG, Olivier; 39 me du Grand- Pre, 1202 GENEVE (CH). LETI, Mathieu; 15 Lotisse- ment La Pradelle, 31450 MONTGISCARD (FR). FABRE, Bernard; Lieu-dit Ensemy, 31450 BELBERAUD (FR). (74) Agent: REGIMBEAU; 20, rue de Chazelles, 75847 PARIS CEDEX 17 (FR). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: of inventorship (Rule 4.17(iv)) O © (54) Title: NOVEL SILYBUM MARIANUM ACHENE EXTRACT AND USES THEREOF IN DERMATOLOGY AND DER- 00 MO-COSMETICS 0 (57) : The present invention relates to a Silybum marianum (L.) Gaertn. extract comprising less than0.2% by weight of sily- \" marin with respect to the weight of the dry extract, as well as pharmaceutical and cosmetic compositions containing same, the prepa- C ration method thereof and uses thereof as a medicinal product, particularly in the treatment of acne, seborrhoea, seborrheic dermatitis and/or rosacea.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1656328A FR3053253B1 (en) | 2016-07-01 | 2016-07-01 | NOVEL EXTRACT OF AKENES FROM SILYBUM MARIANUM AND ITS USES IN DERMATOLOGY AND DERMO-COSMETICS |
PCT/EP2017/066349 WO2018002338A1 (en) | 2016-07-01 | 2017-06-30 | Novel silybum marianum achene extract and uses thereof in dermatology and dermo-cosmetics |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201811246RA true SG11201811246RA (en) | 2019-01-30 |
Family
ID=56855709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201811246RA SG11201811246RA (en) | 2016-07-01 | 2017-06-30 | Novel silybum marianum achene extract and uses thereof in dermatology and dermo-cosmetics |
Country Status (20)
Country | Link |
---|---|
US (1) | US11285185B2 (en) |
EP (1) | EP3478309B1 (en) |
JP (1) | JP7233222B2 (en) |
KR (1) | KR102459649B1 (en) |
CN (1) | CN109414466B (en) |
AR (1) | AR108935A1 (en) |
AU (1) | AU2017291242B2 (en) |
BR (1) | BR112018076465B1 (en) |
CA (1) | CA3028025A1 (en) |
CL (1) | CL2018003827A1 (en) |
DK (1) | DK3478309T3 (en) |
ES (1) | ES2882493T3 (en) |
FR (1) | FR3053253B1 (en) |
MX (1) | MX2018016032A (en) |
PL (1) | PL3478309T3 (en) |
PT (1) | PT3478309T (en) |
RU (1) | RU2746724C2 (en) |
SG (1) | SG11201811246RA (en) |
TW (1) | TWI773676B (en) |
WO (1) | WO2018002338A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018105464A1 (en) * | 2016-12-07 | 2018-06-14 | キッコーマン株式会社 | Hyaluronic acid production promoter and cosmetic |
FR3099699A1 (en) | 2019-08-06 | 2021-02-12 | Pierre Fabre Dermo-Cosmetique | Achenes extract from Silybum marianum (L.) Gaertn. to promote hair growth |
FR3113585A1 (en) * | 2020-08-31 | 2022-03-04 | Pierre Fabre Dermo-Cosmetique | Oil of Silybum marianum (L.) Gaertn. in strengthening the barrier function of the skin |
CN116322730A (en) | 2020-10-05 | 2023-06-23 | 科莱恩国际有限公司 | Composition comprising silybum marianum extract as aging therapeutic agent |
FR3142088A1 (en) | 2023-03-28 | 2024-05-24 | BASF BEAUTY CARE SOLUTIONS FRANCE SAS / InstSp | Cosmetic uses of a hydrolyzed extract of Silybum marianum seed cake |
FR3148366A1 (en) * | 2023-05-04 | 2024-11-08 | Pierre Fabre Dermo-Cosmetique | Extracts enriched with oxylipins, from Silybum marianum (L.) Gaertn. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2084569B (en) * | 1980-09-29 | 1984-02-15 | Madaus & Co Dr | Extraction of silymarin |
IT1253431B (en) * | 1991-12-02 | 1995-08-08 | Valetudo S R L | PHARMACEUTICAL PREPARATIONS FOR TOPICAL USE FOR THE TREATMENT OF PSORIASIS AND ATOPIC DERMATITIS |
JP2000169332A (en) * | 1998-12-09 | 2000-06-20 | Kanebo Ltd | Sebum secretion inhibitor and skin cosmetic |
US20070059269A1 (en) * | 2005-08-17 | 2007-03-15 | L'oreal | Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer |
US7303772B2 (en) * | 2005-11-10 | 2007-12-04 | Olalde Rangel Jose Angel | Synergistic phytoceutical compositions |
US20070196318A1 (en) * | 2006-02-22 | 2007-08-23 | Marini Jan L | Cosmetic herbal compositions |
WO2009046116A1 (en) * | 2007-10-01 | 2009-04-09 | Dennis Gross | Skin care products containing multiple enhancers |
FR2940281B1 (en) * | 2008-12-22 | 2011-04-01 | Fabre Pierre Dermo Cosmetique | ESTER OF DIOL AND POLYUNSATURATED FATTY ACID AS ANTI-ACNE AGENT |
JP6039908B2 (en) * | 2012-02-21 | 2016-12-07 | キヤノン株式会社 | IMAGING DEVICE AND IMAGING DEVICE CONTROL METHOD |
US20130323228A1 (en) * | 2012-05-31 | 2013-12-05 | Mary Kay Inc. | Cleansing and anti-acne composition |
CN104673486B (en) * | 2015-02-13 | 2018-07-06 | 安徽嘉旗粮油工程技术有限公司 | A kind of method for extracting Silybum Marianum Gaertn Seed Oil and silymarin simultaneously in the cake from milk thistle |
CN110467348A (en) * | 2019-07-26 | 2019-11-19 | 江苏恒久玻璃科技发展有限公司 | The preparation method of glassware |
-
2016
- 2016-07-01 FR FR1656328A patent/FR3053253B1/en active Active
-
2017
- 2017-06-30 MX MX2018016032A patent/MX2018016032A/en unknown
- 2017-06-30 ES ES17734335T patent/ES2882493T3/en active Active
- 2017-06-30 CA CA3028025A patent/CA3028025A1/en active Pending
- 2017-06-30 BR BR112018076465-5A patent/BR112018076465B1/en active IP Right Grant
- 2017-06-30 JP JP2018568390A patent/JP7233222B2/en active Active
- 2017-06-30 EP EP17734335.7A patent/EP3478309B1/en active Active
- 2017-06-30 AU AU2017291242A patent/AU2017291242B2/en active Active
- 2017-06-30 PT PT177343357T patent/PT3478309T/en unknown
- 2017-06-30 RU RU2018145789A patent/RU2746724C2/en active
- 2017-06-30 KR KR1020187037981A patent/KR102459649B1/en active IP Right Grant
- 2017-06-30 DK DK17734335.7T patent/DK3478309T3/en active
- 2017-06-30 TW TW106122046A patent/TWI773676B/en active
- 2017-06-30 AR ARP170101827A patent/AR108935A1/en unknown
- 2017-06-30 PL PL17734335T patent/PL3478309T3/en unknown
- 2017-06-30 WO PCT/EP2017/066349 patent/WO2018002338A1/en unknown
- 2017-06-30 SG SG11201811246RA patent/SG11201811246RA/en unknown
- 2017-06-30 CN CN201780039477.2A patent/CN109414466B/en active Active
- 2017-06-30 US US16/313,835 patent/US11285185B2/en active Active
-
2018
- 2018-12-27 CL CL2018003827A patent/CL2018003827A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CL2018003827A1 (en) | 2019-02-22 |
US11285185B2 (en) | 2022-03-29 |
TWI773676B (en) | 2022-08-11 |
RU2746724C2 (en) | 2021-04-19 |
RU2018145789A3 (en) | 2020-10-06 |
AU2017291242B2 (en) | 2023-07-06 |
FR3053253A1 (en) | 2018-01-05 |
KR20190026692A (en) | 2019-03-13 |
MX2018016032A (en) | 2019-03-21 |
EP3478309A1 (en) | 2019-05-08 |
BR112018076465B1 (en) | 2022-10-25 |
DK3478309T3 (en) | 2021-07-26 |
CN109414466B (en) | 2021-08-31 |
TW201805016A (en) | 2018-02-16 |
JP7233222B2 (en) | 2023-03-06 |
CN109414466A (en) | 2019-03-01 |
PT3478309T (en) | 2021-08-17 |
RU2018145789A (en) | 2020-08-03 |
KR102459649B1 (en) | 2022-10-26 |
JP2019524677A (en) | 2019-09-05 |
EP3478309B1 (en) | 2021-05-12 |
AU2017291242A1 (en) | 2019-01-17 |
ES2882493T3 (en) | 2021-12-02 |
AR108935A1 (en) | 2018-10-10 |
FR3053253B1 (en) | 2020-01-17 |
PL3478309T3 (en) | 2021-11-22 |
BR112018076465A2 (en) | 2019-04-09 |
CA3028025A1 (en) | 2018-01-04 |
WO2018002338A1 (en) | 2018-01-04 |
US20190175677A1 (en) | 2019-06-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11201811246RA (en) | Novel silybum marianum achene extract and uses thereof in dermatology and dermo-cosmetics | |
SG11201908813QA (en) | Anti-sirp alpha antibodies | |
SG11201810117WA (en) | Human platelet lysate derived extracellular vesicles for use in medicine | |
SG11201908652QA (en) | Pharmaceutical compositions | |
SG11201807913XA (en) | Stabilized soluble pre-fusion rsv f proteins | |
SG11201809908TA (en) | Stabilized glycopeptide antibiotic formulations | |
SG11201811706RA (en) | Process for the preparation of microcapsules | |
SG11201807809XA (en) | A transient commensal microorganism for improving gut health | |
SG11201808108XA (en) | Synthesis of indazoles | |
SG11201808222RA (en) | Methods of treatment of cholestatic diseases | |
SG11201811230RA (en) | Compositions and methods for reducing ocular neovascularization | |
SG11201805311XA (en) | Method of treating a mammal, including human, against cancer using methionine and asparagine depletion | |
SG11201810965YA (en) | 1h-pyrazolo[4,3-b]pyridines as pde1 inhibitors | |
SG11201901986SA (en) | Process for the manufacture of a solid pharmaceutical adminstration form | |
SG11201808106YA (en) | Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation | |
SG11201810078PA (en) | Stabilized pre-fusion rsv f proteins | |
SG11201903061YA (en) | Combination treatments comprising administration of imidazopyrazinones | |
SG11201808686VA (en) | Synthesis of indazoles | |
SG11201805771XA (en) | Systems and methods for preparation of platelets | |
SG11201806393QA (en) | Use of gabaa receptor modulators for treatment of itch | |
SG11201811708QA (en) | Process for the preparation of microcapsules | |
SG11201805649UA (en) | Therapeutic anti-cd9 antibody | |
SG11201811580SA (en) | Compositions, devices, and methods for the treatment of alcohol use disorder | |
SG11202000494UA (en) | Drug delivery composition | |
SG11201408509PA (en) | Racecadotril lipid compositions |