SG11201805149XA - Compositions comprising 15-hepe and methods of using the same - Google Patents
Compositions comprising 15-hepe and methods of using the sameInfo
- Publication number
- SG11201805149XA SG11201805149XA SG11201805149XA SG11201805149XA SG11201805149XA SG 11201805149X A SG11201805149X A SG 11201805149XA SG 11201805149X A SG11201805149X A SG 11201805149XA SG 11201805149X A SG11201805149X A SG 11201805149XA SG 11201805149X A SG11201805149X A SG 11201805149XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- building
- trintech
- dublin
- pct
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 102220240796 rs553605556 Human genes 0.000 abstract 5
- WLKCSMCLEKGITB-XWJJKCKWSA-N 15-HEPE Chemical compound CC\C=C/CC(O)\C=C\C=C/C\C=C/C\C=C/CCCC(O)=O WLKCSMCLEKGITB-XWJJKCKWSA-N 0.000 abstract 2
- 230000008520 organization Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/103671 Al 22 June 2017 (22.06.2017) WIPO I PCT 111111111111110111011111111111010111110 01011111011110011111 0111111111E0111111 (51) International Patent Classification: A61K 31/202 (2006.01) A61P 35/00 A61P 3/08 (2006.01) A61P 25/00 A61P 17/06 (2006.01) A61P 29/00 (21) International Application Number: PCT/IB2016/001878 (22) International Filing Date: 19 December 2016 (19.12.2016) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/269,280 18 December 2015 (18.12.2015) US (71) Applicant: DIGNITY SCIENCES LIMITED [IE/IE]; Trintech Building, South County Business Park, Leopard- stown, Dublin, 18 (IE). (72) Inventors: COUGHLAN, David; C/o Trintech Building, South County Business Park, Leopardstown, Dublin, 18 (IE). CLIMAX, John; C/o Trintech Building, South County Business Park, Leopardstown, Dublin, 18 (IE). (74) Agent: REDDIE & GROSE LLP; The White Chapel Building, 10 Whitechapel High Street, London El 8QS (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (2006.01) (2006.01) (2006.01) 1-1 N Cr) O 1-1 N O 1-1 C (54) Title: COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF USING THE SAME (57) : The present invention relates to the compositions comprising 15-HEPE and methods of treatment relating to same.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562269280P | 2015-12-18 | 2015-12-18 | |
| PCT/IB2016/001878 WO2017103671A1 (en) | 2015-12-18 | 2016-12-19 | Compositions comprising 15-hepe and methods of using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201805149XA true SG11201805149XA (en) | 2018-07-30 |
Family
ID=57995240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201805149XA SG11201805149XA (en) | 2015-12-18 | 2016-12-19 | Compositions comprising 15-hepe and methods of using the same |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US9855238B2 (en) |
| EP (2) | EP3389647B1 (en) |
| JP (4) | JP2018537513A (en) |
| KR (5) | KR20200055154A (en) |
| CN (2) | CN108697680A (en) |
| AR (1) | AR107143A1 (en) |
| AU (3) | AU2016370626B2 (en) |
| BR (2) | BR112018012313A2 (en) |
| CA (2) | CA3129008A1 (en) |
| ES (1) | ES2948444T3 (en) |
| IL (2) | IL294736A (en) |
| MX (2) | MX2018007390A (en) |
| NZ (1) | NZ744323A (en) |
| PH (1) | PH12018501279A1 (en) |
| RU (2) | RU2020137883A (en) |
| SG (1) | SG11201805149XA (en) |
| WO (1) | WO2017103671A1 (en) |
| ZA (2) | ZA201804779B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201301626D0 (en) | 2013-01-30 | 2013-03-13 | Dignity Sciences Ltd | Composition comprising 15-OHEPA and methods of using the same |
| CN109232278A (en) | 2013-11-15 | 2019-01-18 | Ds生物制药有限公司 | The pharmaceutically acceptable salt of how unsaturated hydroxy fatty acid |
| MA41120A (en) | 2014-12-02 | 2017-10-10 | Afimmune Ltd | COMPOSITIONS INCLUDING 15-HEPE AND METHODS OF TREATING OR PREVENTING FIBROSIS USING THEM |
| US10047033B2 (en) | 2015-05-13 | 2018-08-14 | Ds Biopharma Limited | Compositions comprising oxo-derivatives of fatty acids and methods of making and using same |
| EP3861995A1 (en) | 2015-07-21 | 2021-08-11 | Affimune Limited | Compositions comprising 15-hepe for use in treating or preventing neurologic disease |
| EP3389647B1 (en) * | 2015-12-18 | 2023-04-05 | Afimmune Limited | Compositions comprising 15-hepe |
| CN113116878A (en) * | 2020-01-10 | 2021-07-16 | 南京大学 | New use of 15S-HEPE for enhancing T cell mediated tumor immunotherapy |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
| US11622495B2 (en) | 2021-06-01 | 2023-04-11 | Gint Co., Ltd. | Method of automatically combining farm vehicle and work machine and farm vehicle |
| CN113855659B (en) * | 2021-11-24 | 2022-12-23 | 中国人民解放军东部战区总医院 | Use of 12-HEPE or pharmaceutically acceptable fatty acid thereof to ameliorate spermatogenesis disorders |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05186342A (en) | 1992-01-10 | 1993-07-27 | Fujirebio Inc | Antiinflammatory agent having immunoregulatory action |
| JP2000191525A (en) | 1998-12-25 | 2000-07-11 | Nof Corp | Skin medicine composition for external use |
| JP2005179211A (en) | 2003-12-17 | 2005-07-07 | Idemitsu Kosan Co Ltd | External preparation composition for skin |
| EP1711173A2 (en) | 2003-12-31 | 2006-10-18 | Igennus Limited | Formulation containing an eicosapentaenoic acid or an ester thereof and a triterpene or ester thereof |
| WO2005102309A2 (en) | 2004-04-26 | 2005-11-03 | Ltb4 Sweden Ab | In vivo release of endogenous anti-microbial mediators by leukotriene b4 (ltb4) administration |
| JP5504405B2 (en) * | 2005-06-10 | 2014-05-28 | 国立大学法人山口大学 | Food composition effective in preventing vascular disease |
| EP2607902B1 (en) | 2006-08-08 | 2017-10-04 | Metabolon, Inc. | Markers of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) and methods of use thereof |
| GB0802116D0 (en) | 2008-02-05 | 2008-03-12 | Natural Enviromental Res Counc | Treatment |
| JP2010229099A (en) * | 2009-03-27 | 2010-10-14 | Mochida Pharmaceut Co Ltd | Ameliorating or therapeutic drug for dyslipidemia |
| GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
| US8618168B2 (en) * | 2009-05-22 | 2013-12-31 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of OMEGA3 fatty acid |
| WO2012135032A2 (en) | 2011-03-25 | 2012-10-04 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory particles |
| US8293790B2 (en) | 2011-10-19 | 2012-10-23 | Dignity Sciences Limited | Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof |
| JP2014530841A (en) | 2011-10-19 | 2014-11-20 | ディグニティサイエンシスリミテッド | Pharmaceutical composition comprising DGLA and / or 15-HETRE and method of use thereof |
| KR20140113921A (en) | 2011-11-29 | 2014-09-25 | 디그너티 사이언스 리미티드 | Compositions comprising 20-carbon fatty acids and methods of making and using same |
| US20120264705A1 (en) * | 2012-01-26 | 2012-10-18 | Dignity Sciences Limited | Antimicrobial compositions comprising 15-hetre and methods of use thereof |
| US20130267598A1 (en) | 2012-02-23 | 2013-10-10 | Dignity Sciences Limited | Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same |
| AU2013240427B2 (en) * | 2012-03-30 | 2017-08-03 | Sancilio & Company, Inc. | Omega-3 fatty acid ester compositions |
| CA2873055C (en) * | 2012-05-10 | 2023-10-10 | Solutex Na Llc | Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors |
| GB201213484D0 (en) | 2012-07-30 | 2012-09-12 | Dignity Sciences Ltd | Pharmaceutical compositions comprising 15-OHEPA and methods of using the same |
| GB201301626D0 (en) | 2013-01-30 | 2013-03-13 | Dignity Sciences Ltd | Composition comprising 15-OHEPA and methods of using the same |
| US20160158184A1 (en) * | 2013-07-18 | 2016-06-09 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of omega3 fatty acid |
| CN109232278A (en) * | 2013-11-15 | 2019-01-18 | Ds生物制药有限公司 | The pharmaceutically acceptable salt of how unsaturated hydroxy fatty acid |
| WO2015106215A2 (en) * | 2014-01-10 | 2015-07-16 | Mehar Manku | Pharmaceutical compositions comprising 15-hepe and methods of treating asthma and lung disorders using same |
| MA41120A (en) * | 2014-12-02 | 2017-10-10 | Afimmune Ltd | COMPOSITIONS INCLUDING 15-HEPE AND METHODS OF TREATING OR PREVENTING FIBROSIS USING THEM |
| US20180008567A1 (en) * | 2015-01-16 | 2018-01-11 | Afimmune Limited | Compositions comprising 15-hepe and methods of using the same |
| US10047033B2 (en) * | 2015-05-13 | 2018-08-14 | Ds Biopharma Limited | Compositions comprising oxo-derivatives of fatty acids and methods of making and using same |
| EP3861995A1 (en) * | 2015-07-21 | 2021-08-11 | Affimune Limited | Compositions comprising 15-hepe for use in treating or preventing neurologic disease |
| EP3389647B1 (en) * | 2015-12-18 | 2023-04-05 | Afimmune Limited | Compositions comprising 15-hepe |
-
2016
- 2016-12-19 EP EP16834282.2A patent/EP3389647B1/en active Active
- 2016-12-19 KR KR1020207013456A patent/KR20200055154A/en not_active IP Right Cessation
- 2016-12-19 CA CA3129008A patent/CA3129008A1/en active Pending
- 2016-12-19 BR BR112018012313-7A patent/BR112018012313A2/en active Search and Examination
- 2016-12-19 MX MX2018007390A patent/MX2018007390A/en unknown
- 2016-12-19 KR KR1020227008483A patent/KR20220038818A/en not_active Application Discontinuation
- 2016-12-19 RU RU2020137883A patent/RU2020137883A/en unknown
- 2016-12-19 BR BR122023026625-0A patent/BR122023026625A2/en active Search and Examination
- 2016-12-19 KR KR1020247011532A patent/KR20240052856A/en not_active Application Discontinuation
- 2016-12-19 JP JP2018531629A patent/JP2018537513A/en active Pending
- 2016-12-19 CN CN201680082030.9A patent/CN108697680A/en active Pending
- 2016-12-19 ES ES16834282T patent/ES2948444T3/en active Active
- 2016-12-19 KR KR1020237010220A patent/KR20230047501A/en not_active Application Discontinuation
- 2016-12-19 NZ NZ744323A patent/NZ744323A/en unknown
- 2016-12-19 AU AU2016370626A patent/AU2016370626B2/en active Active
- 2016-12-19 SG SG11201805149XA patent/SG11201805149XA/en unknown
- 2016-12-19 EP EP23158607.4A patent/EP4218736A3/en active Pending
- 2016-12-19 WO PCT/IB2016/001878 patent/WO2017103671A1/en active Application Filing
- 2016-12-19 MX MX2021000773A patent/MX2021000773A/en unknown
- 2016-12-19 AR ARP160103915A patent/AR107143A1/en unknown
- 2016-12-19 US US15/383,889 patent/US9855238B2/en active Active
- 2016-12-19 CN CN202110567290.8A patent/CN113230244A/en active Pending
- 2016-12-19 RU RU2018126361A patent/RU2737089C2/en active
- 2016-12-19 KR KR1020187020457A patent/KR20180094516A/en active Application Filing
- 2016-12-19 CA CA3008774A patent/CA3008774C/en active Active
- 2016-12-19 IL IL294736A patent/IL294736A/en unknown
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2017
- 2017-12-14 US US15/841,363 patent/US10231945B2/en active Active
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2018
- 2018-06-06 IL IL259846A patent/IL259846A/en unknown
- 2018-06-14 PH PH12018501279A patent/PH12018501279A1/en unknown
- 2018-07-17 ZA ZA2018/04779A patent/ZA201804779B/en unknown
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2019
- 2019-01-31 US US16/263,486 patent/US20190224154A1/en not_active Abandoned
- 2019-11-27 JP JP2019214063A patent/JP2020063259A/en active Pending
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2020
- 2020-11-11 AU AU2020267224A patent/AU2020267224B2/en active Active
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2021
- 2021-07-15 ZA ZA2021/04969A patent/ZA202104969B/en unknown
- 2021-07-19 JP JP2021118532A patent/JP2021178840A/en active Pending
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2022
- 2022-05-20 US US17/750,262 patent/US20230106655A1/en active Pending
- 2022-12-23 AU AU2022291628A patent/AU2022291628A1/en active Pending
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2023
- 2023-07-21 JP JP2023118782A patent/JP2023153863A/en active Pending
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| Publication | Publication Date | Title |
|---|---|---|
| SG11201805149XA (en) | Compositions comprising 15-hepe and methods of using the same | |
| SG11201909949XA (en) | Targeted immunotolerance | |
| SG11201908813QA (en) | Anti-sirp alpha antibodies | |
| SG11201811431VA (en) | Multispecific antibodies against cd40 and cd137 | |
| SG11201807252QA (en) | Anti-lag-3 antibodies | |
| SG11201809344QA (en) | Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde | |
| SG11201811432WA (en) | Rna for cancer therapy | |
| SG11201808990QA (en) | Compositions for topical application of compounds | |
| SG11201900163PA (en) | Macrocycle kinase inhibitors | |
| SG11201804901WA (en) | Compounds for the treatment of cancer and inflammatory disease | |
| SG11201901020RA (en) | Anti-siglec-7 antibodies for the treatment of cancer | |
| SG11201907023UA (en) | Method of reducing neutropenia | |
| SG11201808713YA (en) | Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier | |
| SG11201808222RA (en) | Methods of treatment of cholestatic diseases | |
| SG11201907364WA (en) | Anti-tryptase antibodies, compositions thereof, and uses thereof | |
| SG11201804704PA (en) | Compositions and methods for decreasing tau expression | |
| SG11201809875VA (en) | Compositions and methods for treating spinal muscular atrophy | |
| SG11201805001UA (en) | Method of treating influenza a | |
| SG11201805649UA (en) | Therapeutic anti-cd9 antibody | |
| SG11202000333UA (en) | Bicyclic ketone compounds and methods of use thereof | |
| SG11201808686VA (en) | Synthesis of indazoles | |
| SG11201903061YA (en) | Combination treatments comprising administration of imidazopyrazinones | |
| SG11201901438VA (en) | Solid forms of cenicriviroc mesylate and processes of making solid forms of cenicriviroc mesylate | |
| SG11201909837YA (en) | Methods for treating lung disorders | |
| SG11201806424TA (en) | Therapeutic compounds |