SG11201702082VA - Benzyl substituted indazoles as bub1 inhibitors - Google Patents
Benzyl substituted indazoles as bub1 inhibitorsInfo
- Publication number
- SG11201702082VA SG11201702082VA SG11201702082VA SG11201702082VA SG11201702082VA SG 11201702082V A SG11201702082V A SG 11201702082VA SG 11201702082V A SG11201702082V A SG 11201702082VA SG 11201702082V A SG11201702082V A SG 11201702082VA SG 11201702082V A SG11201702082V A SG 11201702082VA
- Authority
- SG
- Singapore
- Prior art keywords
- benzyl substituted
- substituted indazoles
- bub1 inhibitors
- bub1
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14185604 | 2014-09-19 | ||
| EP15176903 | 2015-07-15 | ||
| PCT/EP2015/071340 WO2016042084A1 (en) | 2014-09-19 | 2015-09-17 | Benzyl substituted indazoles as bub1 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201702082VA true SG11201702082VA (en) | 2017-04-27 |
Family
ID=54140475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201702082VA SG11201702082VA (en) | 2014-09-19 | 2015-09-17 | Benzyl substituted indazoles as bub1 inhibitors |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US10350206B2 (en) |
| EP (1) | EP3194379A1 (en) |
| JP (1) | JP6664385B2 (en) |
| KR (1) | KR20170049604A (en) |
| CN (1) | CN107001331A (en) |
| AP (1) | AP2017009803A0 (en) |
| AU (1) | AU2015316796A1 (en) |
| BR (1) | BR112017005444A2 (en) |
| CA (1) | CA2961589A1 (en) |
| CL (1) | CL2017000654A1 (en) |
| CO (1) | CO2017002532A2 (en) |
| CR (1) | CR20170100A (en) |
| CU (1) | CU20170029A7 (en) |
| DO (1) | DOP2017000078A (en) |
| EA (1) | EA032401B1 (en) |
| EC (1) | ECSP17016797A (en) |
| IL (1) | IL251071A0 (en) |
| MA (1) | MA39484A (en) |
| MX (1) | MX2017003664A (en) |
| NI (1) | NI201700034A (en) |
| PE (1) | PE20170697A1 (en) |
| PH (1) | PH12017500509A1 (en) |
| SG (1) | SG11201702082VA (en) |
| TN (1) | TN2017000092A1 (en) |
| TW (1) | TW201615636A (en) |
| UY (1) | UY36311A (en) |
| WO (1) | WO2016042084A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| UA111754C2 (en) | 2011-10-06 | 2016-06-10 | Байєр Фарма Акцієнгезелльшафт | SUBSTITUTED BENZILINDASOLS FOR THE APPLICATION OF BUB1-KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES |
| LT3495367T (en) | 2012-06-13 | 2021-02-25 | Incyte Holdings Corporation | Substituted tricyclic compounds as fgfr inhibitors |
| SI2986610T1 (en) | 2013-04-19 | 2018-04-30 | Incyte Holdings Corporation | Bicyclic heterocycles as fgfr inhibitors |
| EP3010901B1 (en) | 2013-06-21 | 2017-09-13 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted pyrazoles |
| JP2016525076A (en) | 2013-06-21 | 2016-08-22 | バイエル ファーマ アクチエンゲゼルシャフト | Substituted benzylpyrazoles |
| CA2928998A1 (en) | 2013-10-30 | 2015-05-07 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted pyrazoles |
| LT3406609T (en) | 2014-02-06 | 2024-09-25 | Nxera Pharma Uk Limited | Bicyclic aza compounds as muscarinic receptor agonists |
| ES2708211T3 (en) | 2014-06-17 | 2019-04-09 | Bayer Pharma AG | 3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones |
| US10350206B2 (en) | 2014-09-19 | 2019-07-16 | Bayer Pharma Aktiengesellschaft | Benzyl substituted indazoles as BUB1 inhibitors |
| US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
| MA41551A (en) | 2015-02-20 | 2017-12-26 | Incyte Corp | BICYCLIC HETEROCYCLES USED AS FGFR4 INHIBITORS |
| SG10201913036RA (en) | 2015-02-20 | 2020-02-27 | Incyte Corp | Bicyclic heterocycles as fgfr inhibitors |
| TWI794171B (en) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Combination therapies of hdac inhibitors and pd-l1 inhibitors |
| TWI808055B (en) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Combination therapies of hdac inhibitors and pd-1 inhibitors |
| WO2018122168A1 (en) | 2016-12-29 | 2018-07-05 | Bayer Pharma Aktiengesellschaft | Combinations of bub1 kinase and parp inhibitors |
| WO2018158175A1 (en) | 2017-02-28 | 2018-09-07 | Bayer Pharma Aktiengesellschaft | Combination of bub1 inhibitors |
| US11242335B2 (en) | 2017-04-11 | 2022-02-08 | Sunshine Lake Pharma Co., Ltd. | Fluorine-substituted indazole compounds and uses thereof |
| WO2018206547A1 (en) | 2017-05-12 | 2018-11-15 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and atr inhibitors |
| AR111960A1 (en) | 2017-05-26 | 2019-09-04 | Incyte Corp | CRYSTALLINE FORMS OF A FGFR INHIBITOR AND PROCESSES FOR ITS PREPARATION |
| WO2018215282A1 (en) | 2017-05-26 | 2018-11-29 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and pi3k inhibitors |
| WO2019213544A2 (en) | 2018-05-04 | 2019-11-07 | Incyte Corporation | Solid forms of an fgfr inhibitor and processes for preparing the same |
| EP3788046A1 (en) | 2018-05-04 | 2021-03-10 | Incyte Corporation | Salts of an fgfr inhibitor |
| US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
| US11591329B2 (en) | 2019-07-09 | 2023-02-28 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
| US12122767B2 (en) | 2019-10-01 | 2024-10-22 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
| JP2022552324A (en) | 2019-10-14 | 2022-12-15 | インサイト・コーポレイション | Bicyclic heterocycles as FGFR inhibitors |
| WO2021076728A1 (en) | 2019-10-16 | 2021-04-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
| US11897891B2 (en) | 2019-12-04 | 2024-02-13 | Incyte Corporation | Tricyclic heterocycles as FGFR inhibitors |
| CN115151539A (en) | 2019-12-04 | 2022-10-04 | 因赛特公司 | Derivatives of FGFR inhibitors |
| US12012409B2 (en) | 2020-01-15 | 2024-06-18 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
| CA3215903A1 (en) | 2021-04-12 | 2022-10-20 | Incyte Corporation | Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent |
| CA3220274A1 (en) | 2021-06-09 | 2022-12-15 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
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| US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
| US5470862A (en) | 1995-02-03 | 1995-11-28 | Ohmeda Pharmaceutical Products Division Inc. | Substituted pyrazolyl compounds and methods employing such compounds |
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| DE19846514A1 (en) | 1998-10-09 | 2000-04-20 | Bayer Ag | New arylmethyl and heterocyclylmethyl substituted heteroaryl-indazole derivatives useful in treatment of cardiovascular, ischemic and urogenital disorders |
| ES2295441T3 (en) | 2001-12-18 | 2008-04-16 | MERCK & CO., INC. | MODULATORS OF PIRAZOL HETEROARIL REPLACED 5 METABOTROPIC RECEIVER OF GLUTAMATE. |
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| JP2006503043A (en) | 2002-09-10 | 2006-01-26 | サイオス インク． | TGFβ inhibitor |
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| US8748601B2 (en) | 2003-04-11 | 2014-06-10 | The Regents Of The University Of California | Selective serine/threonine kinase inhibitors |
| WO2005070900A1 (en) | 2004-01-22 | 2005-08-04 | Altana Pharma Ag | N-4-(6- (heteo) aryl-pyrimidin-4-ylaminophenyl) -bezenesulfonamides as kinase inhibitors |
| WO2007065010A2 (en) | 2005-12-02 | 2007-06-07 | Hif Bio, Inc. | Anti-angiogenesis compounds |
| DE102006043443A1 (en) | 2006-09-15 | 2008-03-27 | Bayer Healthcare Ag | Novel aza-bicyclic compounds and their use |
| US8796253B2 (en) | 2007-05-18 | 2014-08-05 | Bayer Intellectual Property Gmbh | Heteroaryl substituted pyrazole derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
| JP2010111624A (en) | 2008-11-06 | 2010-05-20 | Shionogi & Co Ltd | Indazole derivative having ttk inhibitory action |
| JP5580332B2 (en) | 2008-12-18 | 2014-08-27 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | Substituted indazole derivatives active as kinase inhibitors |
| CN102666537A (en) | 2009-10-20 | 2012-09-12 | 艾格尔生物制药股份有限公司 | Azaindazoles to treat flaviviridae virus infection |
| CA2936852C (en) | 2009-11-27 | 2019-10-29 | Adverio Pharma Gmbh | Method for producing methyl-{4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridino-3-yl]pyrimidino-5-yl}methyl carbamate and its purification for use thereof as pharmaceutical substance |
| WO2011115804A1 (en) | 2010-03-17 | 2011-09-22 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| RU2017144535A (en) | 2010-03-30 | 2019-02-18 | Версеон Корпорейшн | MULTI-DISPLACED AROMATIC COMPOUNDS AS THROMBINE INHIBITORS |
| AR088020A1 (en) | 2010-06-30 | 2014-05-07 | Ironwood Pharmaceuticals Inc | HETEROCICLICAL COMPOUNDS AS SGC STIMULATORS |
| UA111754C2 (en) * | 2011-10-06 | 2016-06-10 | Байєр Фарма Акцієнгезелльшафт | SUBSTITUTED BENZILINDASOLS FOR THE APPLICATION OF BUB1-KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES |
| ES2638144T3 (en) | 2011-12-21 | 2017-10-18 | Bayer Intellectual Property Gmbh | Substituted benzylpyrazoles |
| CN106117194A (en) | 2011-12-27 | 2016-11-16 | 铁木医药有限公司 | Can be used as 2 benzyls of SGC stimulant, 3 (pyrimidine 2 base) substituted pyrazoles |
| EP2847180B1 (en) | 2012-05-11 | 2017-01-04 | Bayer Pharma Aktiengesellschaft | Substituted cycloalkenopyrazoles as bub1 inhibitors for the treatment of cancer |
| WO2014047111A1 (en) | 2012-09-18 | 2014-03-27 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| CA2885645A1 (en) | 2012-09-19 | 2014-03-27 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| US9738610B2 (en) | 2012-09-24 | 2017-08-22 | Whitehead Institute For Biomedical Research | Indazole derivatives and uses thereof |
| CA2907594A1 (en) | 2013-03-21 | 2014-09-25 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted indazoles |
| JP2016514718A (en) | 2013-03-21 | 2016-05-23 | バイエル ファーマ アクチエンゲゼルシャフト | 3-heteroaryl substituted indazoles |
| WO2014147144A1 (en) | 2013-03-21 | 2014-09-25 | Bayer Pharma Aktiengesellschaft | Diaminoheteroaryl substituted indazoles |
| JP2016522232A (en) | 2013-06-21 | 2016-07-28 | バイエル ファーマ アクチエンゲゼルシャフト | Heteroaryl-substituted pyrazoles |
| JP2016525076A (en) | 2013-06-21 | 2016-08-22 | バイエル ファーマ アクチエンゲゼルシャフト | Substituted benzylpyrazoles |
| JP2016522231A (en) | 2013-06-21 | 2016-07-28 | バイエル ファーマ アクチエンゲゼルシャフト | Diaminoheteroaryl substituted pyrazoles |
| CA2916097A1 (en) | 2013-06-21 | 2014-12-24 | Bayer Pharma Aktiengesellschaft | Substituted benzylpyrazoles |
| EP3010901B1 (en) | 2013-06-21 | 2017-09-13 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted pyrazoles |
| CA2928998A1 (en) | 2013-10-30 | 2015-05-07 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted pyrazoles |
| PE20170937A1 (en) | 2014-09-19 | 2017-07-13 | Glaxosmithkline Ip Dev Ltd | NEW ACTIVATORS OF SOLUBLE GUANILATE CYCLASE AND ITS USE |
| CN107074825A (en) | 2014-09-19 | 2017-08-18 | 拜耳制药股份公司 | The indazole compounds replaced as the benzyl of BUB1 kinase inhibitors |
| CN107148420A (en) | 2014-09-19 | 2017-09-08 | 拜耳制药股份公司 | The indazole compounds of benzyl substitution |
| EP3194380A1 (en) | 2014-09-19 | 2017-07-26 | Bayer Pharma Aktiengesellschaft | Benzyl substituted indazoles as bub1 kinase inhibitors |
| CN107001328B (en) | 2014-09-19 | 2020-06-05 | 福马治疗股份有限公司 | Pyridin-2 (1H) -one quinolinone derivatives as mutant isocitrate dehydrogenase inhibitors |
| US10350206B2 (en) | 2014-09-19 | 2019-07-16 | Bayer Pharma Aktiengesellschaft | Benzyl substituted indazoles as BUB1 inhibitors |
| AU2015319791A1 (en) | 2014-09-19 | 2017-02-23 | Nestec Sa | Treatment of cancer with alpha-amylase inhibitor in companion animals |
| WO2017148995A1 (en) | 2016-03-04 | 2017-09-08 | Bayer Pharma Aktiengesellschaft | 1-(pyrimidin-2-yl)-1h-indazoles having bub1 kinase inhibiting activity |
| WO2017157991A1 (en) | 2016-03-18 | 2017-09-21 | Bayer Pharma Aktiengesellschaft | 1-alkyl-pyrazoles and -indazoles as bub1 inhibitors for the treatment of hyperproliferative diseases |
| WO2017157992A1 (en) | 2016-03-18 | 2017-09-21 | Bayer Pharma Aktiengesellschaft | Annulated pyrazoles as bub1 kinase inhibitors for treating proliferative disorders |
| WO2018122168A1 (en) | 2016-12-29 | 2018-07-05 | Bayer Pharma Aktiengesellschaft | Combinations of bub1 kinase and parp inhibitors |
| WO2018158175A1 (en) | 2017-02-28 | 2018-09-07 | Bayer Pharma Aktiengesellschaft | Combination of bub1 inhibitors |
| WO2018206547A1 (en) | 2017-05-12 | 2018-11-15 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and atr inhibitors |
| WO2018215282A1 (en) | 2017-05-26 | 2018-11-29 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and pi3k inhibitors |
-
2015
- 2015-09-17 US US15/512,494 patent/US10350206B2/en not_active Expired - Fee Related
- 2015-09-17 KR KR1020177010425A patent/KR20170049604A/en unknown
- 2015-09-17 CN CN201580062951.4A patent/CN107001331A/en active Pending
- 2015-09-17 EA EA201790649A patent/EA032401B1/en not_active IP Right Cessation
- 2015-09-17 JP JP2017514825A patent/JP6664385B2/en not_active Expired - Fee Related
- 2015-09-17 CR CR20170100A patent/CR20170100A/en unknown
- 2015-09-17 MX MX2017003664A patent/MX2017003664A/en unknown
- 2015-09-17 CA CA2961589A patent/CA2961589A1/en not_active Abandoned
- 2015-09-17 CU CUP2017000029A patent/CU20170029A7/en unknown
- 2015-09-17 BR BR112017005444A patent/BR112017005444A2/en not_active IP Right Cessation
- 2015-09-17 SG SG11201702082VA patent/SG11201702082VA/en unknown
- 2015-09-17 WO PCT/EP2015/071340 patent/WO2016042084A1/en active Application Filing
- 2015-09-17 AU AU2015316796A patent/AU2015316796A1/en not_active Abandoned
- 2015-09-17 AP AP2017009803A patent/AP2017009803A0/en unknown
- 2015-09-17 MA MA039484A patent/MA39484A/en unknown
- 2015-09-17 EP EP15763619.2A patent/EP3194379A1/en not_active Withdrawn
- 2015-09-17 PE PE2017000480A patent/PE20170697A1/en unknown
- 2015-09-17 TN TN2017000092A patent/TN2017000092A1/en unknown
- 2015-09-18 TW TW104131025A patent/TW201615636A/en unknown
- 2015-09-18 UY UY0001036311A patent/UY36311A/en not_active Application Discontinuation
-
2017
- 2017-03-09 IL IL251071A patent/IL251071A0/en unknown
- 2017-03-16 PH PH12017500509A patent/PH12017500509A1/en unknown
- 2017-03-17 CL CL2017000654A patent/CL2017000654A1/en unknown
- 2017-03-17 DO DO2017000078A patent/DOP2017000078A/en unknown
- 2017-03-17 CO CONC2017/0002532A patent/CO2017002532A2/en unknown
- 2017-03-17 NI NI201700034A patent/NI201700034A/en unknown
- 2017-03-17 EC ECIEPI201716797A patent/ECSP17016797A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CR20170100A (en) | 2017-04-24 |
| TN2017000092A1 (en) | 2018-07-04 |
| NI201700034A (en) | 2017-06-16 |
| IL251071A0 (en) | 2017-04-30 |
| TW201615636A (en) | 2016-05-01 |
| CL2017000654A1 (en) | 2017-12-11 |
| PH12017500509A1 (en) | 2017-08-30 |
| WO2016042084A1 (en) | 2016-03-24 |
| CN107001331A (en) | 2017-08-01 |
| EA201790649A1 (en) | 2017-09-29 |
| MA39484A (en) | 2016-03-24 |
| UY36311A (en) | 2016-04-29 |
| EA032401B1 (en) | 2019-05-31 |
| US20170273980A1 (en) | 2017-09-28 |
| PE20170697A1 (en) | 2017-06-24 |
| MX2017003664A (en) | 2017-07-13 |
| US10350206B2 (en) | 2019-07-16 |
| CO2017002532A2 (en) | 2017-07-11 |
| CU20170029A7 (en) | 2017-08-08 |
| CA2961589A1 (en) | 2016-03-24 |
| JP6664385B2 (en) | 2020-03-13 |
| KR20170049604A (en) | 2017-05-10 |
| BR112017005444A2 (en) | 2018-04-24 |
| EP3194379A1 (en) | 2017-07-26 |
| DOP2017000078A (en) | 2017-06-30 |
| JP2017530962A (en) | 2017-10-19 |
| AU2015316796A1 (en) | 2017-03-30 |
| AP2017009803A0 (en) | 2017-03-31 |
| ECSP17016797A (en) | 2017-05-31 |
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