SG11201701540PA - Method of fabricating cell arrays and uses thereof - Google Patents
Method of fabricating cell arrays and uses thereofInfo
- Publication number
- SG11201701540PA SG11201701540PA SG11201701540PA SG11201701540PA SG11201701540PA SG 11201701540P A SG11201701540P A SG 11201701540PA SG 11201701540P A SG11201701540P A SG 11201701540PA SG 11201701540P A SG11201701540P A SG 11201701540PA SG 11201701540P A SG11201701540P A SG 11201701540PA
- Authority
- SG
- Singapore
- Prior art keywords
- cell arrays
- fabricating cell
- fabricating
- arrays
- cell
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5073—Stem cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/0036—Nozzles
- B01J2219/00362—Acoustic nozzles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00531—Sheets essentially square
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00709—Type of synthesis
- B01J2219/00711—Light-directed synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/0074—Biological products
- B01J2219/00743—Cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462070508P | 2014-08-28 | 2014-08-28 | |
PCT/US2015/047494 WO2016033501A1 (en) | 2014-08-28 | 2015-08-28 | Method of fabricating cell arrays and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201701540PA true SG11201701540PA (en) | 2017-03-30 |
Family
ID=54073022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201701540PA SG11201701540PA (en) | 2014-08-28 | 2015-08-28 | Method of fabricating cell arrays and uses thereof |
Country Status (5)
Country | Link |
---|---|
US (2) | US10625234B2 (en) |
EP (1) | EP3186632A1 (en) |
JP (1) | JP6510649B2 (en) |
SG (1) | SG11201701540PA (en) |
WO (1) | WO2016033501A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201701540PA (en) | 2014-08-28 | 2017-03-30 | Stemonix Inc | Method of fabricating cell arrays and uses thereof |
US11248212B2 (en) | 2015-06-30 | 2022-02-15 | StemoniX Inc. | Surface energy directed cell self assembly |
US20180251726A1 (en) * | 2015-08-21 | 2018-09-06 | StemoniX Inc. | Microwell plate with laminated micro embossed film bottom |
WO2017066663A1 (en) | 2015-10-15 | 2017-04-20 | Carromeu Cassiano | Method of manufacturing cells using a hollow fiber bioreactor |
GB2567360B (en) * | 2016-08-05 | 2022-03-16 | Harvard College | Methods for optical micropatterning of hydrogels and uses thereof |
WO2018183446A1 (en) | 2017-03-28 | 2018-10-04 | The Board Of Trustees Of The Leland Stanford Junior University | Assembly of functionally integrated human forebrain spheroids and methods of use thereof |
US11760974B2 (en) | 2017-04-13 | 2023-09-19 | The Board Of Trustees Of The Leland Stanford Junior University | Personalized 3D neural culture system for generating human oligodendrocytes and studying myelination in vitro |
KR102302776B1 (en) * | 2019-10-11 | 2021-09-23 | 주식회사 싸이토딕스 | A DISK SEPARATING PBMCs USING PHOTOSENSITIVE HYDROGEL |
WO2024150682A1 (en) * | 2023-01-11 | 2024-07-18 | 住友化学株式会社 | Cell chip |
Family Cites Families (43)
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US5981268A (en) | 1997-05-30 | 1999-11-09 | Board Of Trustees, Leland Stanford, Jr. University | Hybrid biosensors |
WO1999039829A1 (en) | 1998-02-04 | 1999-08-12 | Merck & Co., Inc. | Virtual wells for use in high throughput screening assays |
DE60011429T3 (en) | 1999-07-07 | 2010-07-08 | 3M Innovative Properties Co., Saint Paul | DETECTION DEVICE WITH A FLUID CONTROL FILM LAYER WITH CAPILLARY CHANNELS |
US20020049160A1 (en) | 2000-08-22 | 2002-04-25 | Huang Li-Yen Mae | New strategy for drug design |
US7332286B2 (en) * | 2001-02-02 | 2008-02-19 | University Of Pennsylvania | Peptide or protein microassay method and apparatus |
WO2004006840A2 (en) * | 2002-07-12 | 2004-01-22 | The Regents Of The University Of California | Three dimensional cell patterned bioploymer scaffolds and method of making the same |
EP1687404A2 (en) * | 2003-10-14 | 2006-08-09 | The Board Of Trustees Of The University Of Illinois | Methods and compositions related to a matrix chip |
US20070017530A1 (en) | 2005-06-10 | 2007-01-25 | Syed Naweed I | Detecting electrical activity and assessing agents for the ability to influence electrical activity |
US20070122392A1 (en) * | 2005-06-22 | 2007-05-31 | Sharon Gerecht-Nir | Propagation of undifferentiated embryonic stem cells in hyaluronic acid hydrogel |
US7625552B2 (en) | 2006-05-30 | 2009-12-01 | Boston Scientific Scimed, Inc. | Bioactive polymers for imparting bioactive character to hydrophobic medical article surfaces |
KR100838013B1 (en) | 2006-06-07 | 2008-06-12 | 제일약품주식회사 | Efficient Generation of Neural Progenitors, Neurons and Dopaminergic Neurons from Human Embryonic Stem Cells |
US20080193536A1 (en) | 2006-08-14 | 2008-08-14 | Alireza Khademhosseini | Cell-Laden Hydrogels |
JP5583312B2 (en) * | 2007-02-20 | 2014-09-03 | 富士フイルム株式会社 | Tissue formation substrate, tissue formation kit, tissue formation method using the same, and three-dimensional tissue formed by the tissue formation method |
US8288513B2 (en) | 2008-07-25 | 2012-10-16 | Becton, Dickinson And Company | Defined cell culturing surfaces and methods of use |
US20100055733A1 (en) * | 2008-09-04 | 2010-03-04 | Lutolf Matthias P | Manufacture and uses of reactive microcontact printing of biomolecules on soft hydrogels |
AU2009288657A1 (en) | 2008-09-04 | 2010-03-11 | Galenea Corp. | Synaptic vesicle cycling assays and systems |
FR2937050A1 (en) | 2008-10-10 | 2010-04-16 | Inst Curie | CELL CULTURE DEVICE |
US9290756B2 (en) | 2008-11-10 | 2016-03-22 | The Board Of Trustees Of The University Of Illinois | Apparatus and methods for high throughput network electrophysiology and cellular analysis |
US20130172985A1 (en) * | 2010-01-15 | 2013-07-04 | University Of Utah Research Foundation | Crosslinked hydrogels and methods of making and using thereof |
US20130217113A1 (en) | 2010-07-15 | 2013-08-22 | Advanced Liquid Logic Inc. | System for and methods of promoting cell lysis in droplet actuators |
US9234171B2 (en) | 2010-12-08 | 2016-01-12 | Rutgers, The State University Of New Jersey | Stem cell differentiation using novel light-responsive hydrogels |
CN102156158B (en) | 2010-12-28 | 2013-03-20 | 重庆大学 | Device for culturing and measuring microfluidic chip by using topological diagram type nerve cell network |
KR101955053B1 (en) | 2011-06-06 | 2019-03-06 | 리제네시스 비브이비에이 | Expansion of stem cells in hollow fiber bioreactors |
US20130029421A1 (en) | 2011-07-26 | 2013-01-31 | Kyriakos Komvopoulos | Methods for Making Cell Culture Substrates |
CN102911912B (en) | 2011-08-01 | 2014-12-31 | 清华大学 | Culture matrix and nerve graft by using same |
EP2612908A3 (en) | 2012-01-04 | 2014-10-15 | Technion Research & Development Foundation Limited | Optically sensitive cell network |
US8912006B2 (en) | 2012-02-03 | 2014-12-16 | The Charles Stark Draper Laboratory, Inc. | Microfluidic device for generating neural cells to simulate post-stroke conditions |
US9688741B2 (en) | 2012-10-23 | 2017-06-27 | Elastagen Pty Ltd | Elastic hydrogel |
US9932559B2 (en) | 2012-11-16 | 2018-04-03 | The Johns Hopkins University | Platform for creating an artificial blood brain barrier |
US9605253B2 (en) | 2013-01-14 | 2017-03-28 | Massachusetts Institute Of Technology | Electrokinetic confinement of neurite growth for dynamically configurable neural networks |
CN105247070A (en) | 2013-03-15 | 2016-01-13 | 怀特黑德生物医学研究院 | Cellular discovery platform for neurodegenerative diseases |
JP2016518117A (en) | 2013-03-15 | 2016-06-23 | ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャリゼーション | Devices and methods comprising microelectrode arrays for conductive cells |
WO2015069943A1 (en) | 2013-11-06 | 2015-05-14 | L & J Biosciences Inc. | Continuously controlled hollow fiber bioreactor |
DE102014003465A1 (en) | 2014-03-11 | 2015-09-17 | NeuroProof GmbH | Obtaining brain region-specific neuronal cultures from three-dimensional tissue cultures of stem cells |
SG11201701540PA (en) | 2014-08-28 | 2017-03-30 | Stemonix Inc | Method of fabricating cell arrays and uses thereof |
US11820975B2 (en) | 2014-12-09 | 2023-11-21 | National Research Council Of Canada | Human blood brain barrier model |
US11248212B2 (en) | 2015-06-30 | 2022-02-15 | StemoniX Inc. | Surface energy directed cell self assembly |
WO2017066663A1 (en) | 2015-10-15 | 2017-04-20 | Carromeu Cassiano | Method of manufacturing cells using a hollow fiber bioreactor |
WO2017100705A1 (en) | 2015-12-09 | 2017-06-15 | Robert John Petcavich | Mammalian cell in vitro topological neuron network |
US20190177691A1 (en) | 2016-08-02 | 2019-06-13 | StemoniX Inc. | Microelectronic human blood brain barrier |
WO2018026925A1 (en) | 2016-08-05 | 2018-02-08 | StemoniX Inc. | Vascular tubular human blood brain barrier device |
WO2018075890A1 (en) | 2016-10-21 | 2018-04-26 | StemoniX Inc. | Electronic neuron pain assay |
WO2018187686A1 (en) | 2017-04-07 | 2018-10-11 | StemoniX Inc. | Method of manufacturing and purifying exosomes from non-terminally differentiated cells |
-
2015
- 2015-08-28 SG SG11201701540PA patent/SG11201701540PA/en unknown
- 2015-08-28 EP EP15762878.5A patent/EP3186632A1/en not_active Withdrawn
- 2015-08-28 JP JP2017530976A patent/JP6510649B2/en active Active
- 2015-08-28 US US14/839,170 patent/US10625234B2/en active Active
- 2015-08-28 WO PCT/US2015/047494 patent/WO2016033501A1/en active Application Filing
-
2020
- 2020-01-09 US US16/738,408 patent/US20200353438A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20160059203A1 (en) | 2016-03-03 |
US10625234B2 (en) | 2020-04-21 |
EP3186632A1 (en) | 2017-07-05 |
US20200353438A1 (en) | 2020-11-12 |
JP6510649B2 (en) | 2019-05-08 |
JP2017532061A (en) | 2017-11-02 |
WO2016033501A1 (en) | 2016-03-03 |
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