SG11201608424WA - Rapid-acting insulin compositions - Google Patents

Rapid-acting insulin compositions

Info

Publication number: SG11201608424WA
Authority: SG; Singapore
Prior art keywords: rapid; acting insulin; insulin compositions; compositions; acting
Prior art date: 2014-05-08

Application number

SG11201608424WA

Inventor

Michael Edward Christe

Thomas Andrew Hardy

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-05-08

Filing date

2015-05-04

Publication date

2016-11-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53189204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201608424W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-05-04 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2016-11-29 Publication of SG11201608424WA publication Critical patent/SG11201608424WA/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
- A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Hematology (AREA)
Inorganic Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Emergency Medicine (AREA)
Dermatology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

SG11201608424WA 2014-05-08 2015-05-04 Rapid-acting insulin compositions SG11201608424WA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201461990402P	2014-05-08	2014-05-08
PCT/US2015/029010 WO2015171484A1 (en)	2014-05-08	2015-05-04	Rapid-acting insulin compositions

Publications (1)

Publication Number	Publication Date
SG11201608424WA true SG11201608424WA (en)	2016-11-29

Family

ID=53189204

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG11201608424WA SG11201608424WA (en)	2014-05-08	2015-05-04	Rapid-acting insulin compositions

Country Status (36)

Country	Link
US (2)	US9439952B2 (en)
EP (3)	EP3943155A1 (en)
JP (1)	JP6050902B2 (en)
KR (1)	KR101858890B1 (en)
CN (1)	CN106456717B (en)
AP (1)	AP2016009525A0 (en)
AR (1)	AR100155A1 (en)
AU (1)	AU2015256355B2 (en)
BR (1)	BR112016024357B1 (en)
CA (1)	CA2945188C (en)
CL (1)	CL2016002772A1 (en)
CY (2)	CY1121669T1 (en)
DK (2)	DK3140008T3 (en)
EA (1)	EA031134B1 (en)
ES (2)	ES2891983T3 (en)
HR (2)	HRP20190777T1 (en)
HU (2)	HUE044370T2 (en)
IL (1)	IL248350B (en)
JO (1)	JO3624B1 (en)
LT (2)	LT3536380T (en)
MA (1)	MA39441A1 (en)
ME (1)	ME03384B (en)
MX (1)	MX367521B (en)
NZ (1)	NZ724919A (en)
PE (1)	PE20161408A1 (en)
PH (1)	PH12016502195B1 (en)
PL (2)	PL3536380T3 (en)
PT (2)	PT3140008T (en)
RS (2)	RS62291B1 (en)
SG (1)	SG11201608424WA (en)
SI (2)	SI3140008T1 (en)
TN (1)	TN2016000443A1 (en)
TR (1)	TR201906843T4 (en)
TW (1)	TWI685348B (en)
UA (1)	UA124919C2 (en)
WO (1)	WO2015171484A1 (en)

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PT2910570T (en)	2008-03-18	2017-01-24	Novo Nordisk As	Protease stabilized, acylated insulin analogues
CN104902922B (en)	2012-11-13	2017-12-12	阿道恰公司	Include the Insulin Aspart for being substituted anionic compound
US9505737B2 (en)	2013-01-11	2016-11-29	Corsair Pharma, Inc.	Treprostinil derivative compounds and methods of using same
ES2927844T3 (en)	2013-01-11	2022-11-11	Corsair Pharma Inc	Treprostinil Prodrugs
EP3328388B1 (en) *	2015-07-28	2023-12-27	Eli Lilly and Company	A pharmaceutical preparation for improving absorption and postprandial hypoglycemic action of insulin
JO3749B1 (en) *	2015-08-27	2021-01-31	Lilly Co Eli	Rapid-acting insulin compositions
AU2017211410B2 (en) *	2016-01-29	2022-10-13	Mannkind Corporation	Dry powder inhaler
GB201607918D0 (en)	2016-05-06	2016-06-22	Arecor Ltd	Novel formulations
CA3038276A1 (en)	2016-09-26	2018-03-29	United Therapeutics Corporation	Treprostinil prodrugs
AU2017334290B2 (en)	2016-09-29	2023-04-20	Arecor Limited	Novel formulations
IL300839B2 (en)	2016-12-16	2024-04-01	Novo Nordisk As	Insulin containing pharmaceutical compositions
GB201707188D0 (en)	2017-05-05	2017-06-21	Arecor Ltd	Novel formulations
GB201707189D0 (en)	2017-05-05	2017-06-21	Arecor Ltd	Novel formulations
GB201707187D0 (en)	2017-05-05	2017-06-21	Arecor Ltd	Novel formulations
US11207384B2 (en) *	2017-06-01	2021-12-28	Eli Lilly And Company	Rapid-acting insulin compositions
CA3094308A1 (en)	2018-04-04	2019-10-10	Arecor Limited	Medical infusion pump system for the delivery of an insulin compound
IL277721B2 (en)	2018-04-04	2024-03-01	Arecor Ltd	Medical infusion pump system for the delivery of an insulin compound
CN112004521A (en) *	2018-04-04	2020-11-27	艾瑞克有限公司	Medical infusion pump system for delivering insulin compounds
FR3083985A1 (en)	2018-07-23	2020-01-24	Adocia	DEVICE FOR INJECTING AN INSULIN SOLUTION (S)
WO2019243627A1 (en)	2018-06-23	2019-12-26	Adocia	Device for injecting an insulin solution
KR102659451B1 (en)	2018-09-18	2024-04-23	일라이 릴리 앤드 캄파니	Erbumin salt of treprostinil
US10799564B1 (en) *	2019-05-06	2020-10-13	Baxter International Inc.	Insulin premix formulation and product, methods of preparing same, and methods of using same
EP3996679B1 (en) *	2019-07-12	2023-09-06	Novo Nordisk A/S	High concentration insulin formulation
AU2020337342A1 (en)	2019-08-23	2022-02-24	United Therapeutics Corporation	Treprostinil prodrugs
GB202004814D0 (en)	2020-04-01	2020-05-13	Arecor Ltd	Novel formulations
EP4135707A1 (en)	2020-04-17	2023-02-22	United Therapeutics Corporation	Treprostinil for use in the treatment of intersitial lung disease
IL298591A (en)	2020-06-09	2023-01-01	United Therapeutics Corp	Fumaryl diketopiperidine prodrugs of treprostinil
WO2022002008A1 (en) *	2020-06-30	2022-01-06	江苏恒瑞医药股份有限公司	Quick-acting insulin composition and medical use thereof
CN117062605A (en)	2020-12-14	2023-11-14	联合治疗公司	Methods of treating diseases using treprostinil prodrugs

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2740953A1 (en)	1977-09-12	1979-03-22	Thera Ges Fuer Patente	USE OF PROSTAGLANDINES TO LOWER BLOOD SUGAR LEVELS
JPH10251146A (en) *	1997-03-11	1998-09-22	Toray Ind Inc	Treatment of diabetic neuropathy
MXPA04001560A (en) *	2001-08-28	2004-05-17	Lilly Co Eli	Pre-mixes of glp-1 and basal insulin.
DE60335797D1 (en) *	2002-05-07	2011-03-03	Novo Nordisk As	SOLUBLE FORMULATIONS CONTAINING MONOMERIC INSULIN AND ACYLATED INSULIN
US7879909B2 (en)	2004-04-12	2011-02-01	United Therapeutics Corporation	Use of Treprostinil to treat neuropathic diabetic foot ulcers
CA2904447C (en) *	2007-08-22	2017-01-03	Abbvie Deutschland Gmbh & Co Kg	Therapy for complications of diabetes
EP2328636B1 (en)	2008-08-28	2013-06-12	Medingo Ltd.	Device for enhanced subcutaneous insulin absorption
WO2010036798A1 (en) *	2008-09-25	2010-04-01	Aradigm Corporation	Deep lung pulmonary delivery of treprostinil
EP2612677B1 (en) *	2009-06-26	2015-05-06	Novo Nordisk A/S	Preparation comprising insulin, nicotinamide and arginine
ES2525748T3 (en) *	2009-11-13	2014-12-29	Toray Industries, Inc.	Therapeutic or prophylactic agent for diabetes
RU2013130374A (en)	2010-12-14	2015-01-20	Ново Нордиск А/С	THE PRODUCT CONTAINING INSULIN, NICOTINAMIDE AND AMINO ACID
EP2741781A1 (en) *	2011-08-12	2014-06-18	Ascendis Pharma A/S	Carrier-linked treprostinil prodrugs
US9381247B2 (en) *	2012-04-16	2016-07-05	Biodel Inc.	Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
WO2015031709A1 (en)	2013-08-30	2015-03-05	Perosphere, Inc.	Rapid acting injectable formulations comprising a peptide and a vasodilatory agent
WO2015120457A1 (en)	2014-02-10	2015-08-13	Biodel Inc.	Stabilized ultra-rapid-acting insulin formulations

2015
- 2015-04-21 TW TW104112752A patent/TWI685348B/en active
- 2015-04-21 JO JOP/2015/0079A patent/JO3624B1/en active
- 2015-04-22 AR ARP150101208A patent/AR100155A1/en not_active Application Discontinuation
- 2015-05-04 EP EP21183262.1A patent/EP3943155A1/en not_active Withdrawn
- 2015-05-04 TR TR2019/06843T patent/TR201906843T4/en unknown
- 2015-05-04 CN CN201580024110.4A patent/CN106456717B/en active Active
- 2015-05-04 TN TN2016000443A patent/TN2016000443A1/en unknown
- 2015-05-04 AU AU2015256355A patent/AU2015256355B2/en active Active
- 2015-05-04 SG SG11201608424WA patent/SG11201608424WA/en unknown
- 2015-05-04 EA EA201691911A patent/EA031134B1/en active Protection Beyond IP Right Term
- 2015-05-04 ME MEP-2019-126A patent/ME03384B/en unknown
- 2015-05-04 LT LTEP19161129.2T patent/LT3536380T/en unknown
- 2015-05-04 ES ES19161129T patent/ES2891983T3/en active Active
- 2015-05-04 PL PL19161129T patent/PL3536380T3/en unknown
- 2015-05-04 KR KR1020167031043A patent/KR101858890B1/en active IP Right Grant
- 2015-05-04 RS RS20211085A patent/RS62291B1/en unknown
- 2015-05-04 AP AP2016009525A patent/AP2016009525A0/en unknown
- 2015-05-04 NZ NZ724919A patent/NZ724919A/en unknown
- 2015-05-04 EP EP15723388.3A patent/EP3140008B1/en active Active
- 2015-05-04 MA MA39441A patent/MA39441A1/en unknown
- 2015-05-04 SI SI201530716T patent/SI3140008T1/en unknown
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- 2015-05-04 SI SI201531655T patent/SI3536380T1/en unknown
- 2015-05-04 CA CA2945188A patent/CA2945188C/en active Active
- 2015-05-04 ES ES15723388T patent/ES2733639T3/en active Active
- 2015-05-04 PE PE2016002179A patent/PE20161408A1/en unknown
- 2015-05-04 UA UAA201611280A patent/UA124919C2/en unknown
- 2015-05-04 LT LTEP15723388.3T patent/LT3140008T/en unknown
- 2015-05-04 PT PT15723388T patent/PT3140008T/en unknown
- 2015-05-04 PT PT191611292T patent/PT3536380T/en unknown
- 2015-05-04 WO PCT/US2015/029010 patent/WO2015171484A1/en active Application Filing
- 2015-05-04 BR BR112016024357-9A patent/BR112016024357B1/en active IP Right Grant
- 2015-05-04 HU HUE15723388 patent/HUE044370T2/en unknown
- 2015-05-04 JP JP2015563152A patent/JP6050902B2/en active Active
- 2015-05-04 DK DK15723388.3T patent/DK3140008T3/en active
- 2015-05-04 EP EP19161129.2A patent/EP3536380B8/en active Active
- 2015-05-04 DK DK19161129.2T patent/DK3536380T3/en active
- 2015-05-04 HU HUE19161129A patent/HUE055742T2/en unknown
- 2015-05-04 MX MX2016014643A patent/MX367521B/en active IP Right Grant
- 2015-05-04 US US14/781,342 patent/US9439952B2/en active Active
- 2015-05-04 RS RS20190582A patent/RS58726B1/en unknown
2016
- 2016-09-08 US US15/259,101 patent/US10172922B2/en active Active
- 2016-10-13 IL IL248350A patent/IL248350B/en active IP Right Grant
- 2016-11-02 CL CL2016002772A patent/CL2016002772A1/en unknown
- 2016-11-04 PH PH12016502195A patent/PH12016502195B1/en unknown
2019
- 2019-04-25 HR HRP20190777TT patent/HRP20190777T1/en unknown
- 2019-05-31 CY CY20191100581T patent/CY1121669T1/en unknown
2021
- 2021-08-20 CY CY20211100747T patent/CY1124454T1/en unknown
- 2021-09-07 HR HRP20211415TT patent/HRP20211415T1/en unknown

Also Published As

Publication number	Publication date
PT3536380T (en)	2021-09-02
UA124919C2 (en)	2021-12-15
CA2945188C (en)	2018-12-11
PT3140008T (en)	2019-06-25
JP6050902B2 (en)	2016-12-21
MA39441A1 (en)	2017-06-30
EP3943155A1 (en)	2022-01-26
RS62291B1 (en)	2021-09-30
EP3140008A1 (en)	2017-03-15
SI3140008T1 (en)	2019-06-28
CN106456717B (en)	2020-01-17
PE20161408A1 (en)	2016-12-28
US20160129087A1 (en)	2016-05-12
ES2891983T3 (en)	2022-02-01
TW201625291A (en)	2016-07-16
MX367521B (en)	2019-08-26
KR101858890B1 (en)	2018-05-16
US10172922B2 (en)	2019-01-08
PL3536380T3 (en)	2021-12-27
US9439952B2 (en)	2016-09-13
BR112016024357B1 (en)	2022-08-23
TN2016000443A1 (en)	2018-04-04
DK3140008T3 (en)	2019-06-24
IL248350B (en)	2020-03-31
AU2015256355B2 (en)	2017-09-14
EA031134B1 (en)	2018-11-30
ME03384B (en)	2020-01-20
HUE044370T2 (en)	2019-10-28
CA2945188A1 (en)	2015-11-12
AR100155A1 (en)	2016-09-14
PH12016502195A1 (en)	2017-02-06
AU2015256355A1 (en)	2016-10-27
TR201906843T4 (en)	2019-05-21
CL2016002772A1 (en)	2017-06-09
HUE055742T2 (en)	2021-12-28
EP3536380A1 (en)	2019-09-11
ES2733639T3 (en)	2019-12-02
BR112016024357A2 (en)	2017-10-10
SI3536380T1 (en)	2021-09-30
EP3536380B8 (en)	2021-09-22
NZ724919A (en)	2018-01-26
LT3140008T (en)	2019-05-27
LT3536380T (en)	2021-08-10
DK3536380T3 (en)	2021-08-02
CN106456717A (en)	2017-02-22
JP2016523807A (en)	2016-08-12
PL3140008T3 (en)	2019-09-30
RS58726B1 (en)	2019-06-28
TWI685348B (en)	2020-02-21
PH12016502195B1 (en)	2017-02-06
EA201691911A1 (en)	2017-02-28
HRP20211415T1 (en)	2021-12-10
MX2016014643A (en)	2017-03-06
KR20160133567A (en)	2016-11-22
EP3536380B1 (en)	2021-07-07
CY1121669T1 (en)	2020-07-31
WO2015171484A1 (en)	2015-11-12
AP2016009525A0 (en)	2016-10-31
CY1124454T1 (en)	2022-07-22
JO3624B1 (en)	2020-08-27
HRP20190777T1 (en)	2019-08-23
EP3140008B1 (en)	2019-04-17
IL248350A0 (en)	2016-11-30
US20160367640A1 (en)	2016-12-22

Publication	Publication Date	Title
IL248350B (en)	2020-03-31	Rapid-acting insulin compositions
PT3233108T (en)	2022-05-05	Rapid-acting insulin compositions
ZA201800511B (en)	2019-07-31	Rapid-acting insulin compositions
HK1218859A1 (en)	2017-03-17	Composition
GB201410905D0 (en)	2014-08-06	Composition
GB201403017D0 (en)	2014-04-09	Composition
ZA201704464B (en)	2020-10-28	Composition
GB201414910D0 (en)	2014-10-08	Composition
GB201403561D0 (en)	2014-04-16	Composition
GB201414555D0 (en)	2014-10-01	Composition
GB201410493D0 (en)	2014-07-30	Composition
ZA201606127B (en)	2018-05-30	Composition
GB201420628D0 (en)	2015-01-07	Composition
GB201415483D0 (en)	2014-10-15	Composition
GB201404390D0 (en)	2014-04-23	Composition
IL270975A (en)	2020-01-30	Rapid-acting insulin compositions
GB201412414D0 (en)	2014-08-27	Composition
GB201412314D0 (en)	2014-08-27	Composition
GB201402487D0 (en)	2014-03-26	Composition
GB201401510D0 (en)	2014-03-12	Composition