SG11201505192RA - Chromatographic purification of antibodies from chromatin-deficient cell culture harvests - Google Patents
Chromatographic purification of antibodies from chromatin-deficient cell culture harvestsInfo
- Publication number
- SG11201505192RA SG11201505192RA SG11201505192RA SG11201505192RA SG11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA
- Authority
- SG
- Singapore
- Prior art keywords
- chromatin
- antibodies
- cell culture
- chromatographic purification
- deficient cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
- C07K1/32—Extraction; Separation; Purification by precipitation as complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361771021P | 2013-02-28 | 2013-02-28 | |
| PCT/SG2014/000088 WO2014133459A1 (en) | 2013-02-28 | 2014-02-27 | Chromatographic purification of antibodies from chromatin-deficient cell culture harvests |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201505192RA true SG11201505192RA (en) | 2015-08-28 |
Family
ID=51428597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201505192RA SG11201505192RA (en) | 2013-02-28 | 2014-02-27 | Chromatographic purification of antibodies from chromatin-deficient cell culture harvests |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9994611B2 (en) |
| EP (1) | EP2961763A4 (en) |
| JP (1) | JP2016509068A (en) |
| KR (1) | KR20150123796A (en) |
| CN (1) | CN105189530B (en) |
| SG (1) | SG11201505192RA (en) |
| WO (1) | WO2014133459A1 (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2902799B1 (en) | 2006-06-27 | 2012-10-26 | Millipore Corp | METHOD AND UNIT FOR PREPARING A SAMPLE FOR THE MICROBIOLOGICAL ANALYSIS OF A LIQUID |
| WO2008079280A1 (en) | 2006-12-21 | 2008-07-03 | Millipore Corporation | Purification of proteins |
| US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
| US8569464B2 (en) | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
| EP2370561B1 (en) | 2008-12-16 | 2019-08-07 | EMD Millipore Corporation | Stirred tank reactor and method |
| BR112012028977B1 (en) | 2010-05-17 | 2020-05-05 | Emd Millipore Corp | biomolecule purification method by means of stimulus-responsive polymers |
| WO2013180647A1 (en) * | 2012-05-31 | 2013-12-05 | Agency For Science, Technology And Research | Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities |
| US10112971B2 (en) * | 2013-02-26 | 2018-10-30 | Agency For Science, Technology And Research | Protein purification in the presence of nonionic organic polymers and electropositive surfaces |
| CN105263946A (en) * | 2013-06-04 | 2016-01-20 | 新加坡科技研究局 | Protein purification process |
| EP3107927A4 (en) | 2014-02-19 | 2017-08-30 | Agency For Science, Technology And Research | Fractionation method |
| US10103547B2 (en) | 2014-02-21 | 2018-10-16 | Solarlytics, Inc. | Method and system for applying electric fields to multiple solar panels |
| US10023609B2 (en) * | 2014-02-27 | 2018-07-17 | Agency For Science, Research And Technology | Methods for reducing chromatin content in protein preparations by treatment with alkyl cations |
| JP2019108274A (en) * | 2016-04-18 | 2019-07-04 | 昭和電工株式会社 | Removing method of protein aggregate |
| US10927145B2 (en) | 2016-06-15 | 2021-02-23 | Agency For Science, Technology And Research | Method of enhancing the performance of chromatography methods for purification of proteins |
| GB201801842D0 (en) * | 2018-02-05 | 2018-03-21 | Swedish Biomimetics 3000 Ltd | Affinity chromatography |
| US11155575B2 (en) | 2018-03-21 | 2021-10-26 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbent, devices and methods |
| HU231498B1 (en) | 2019-04-04 | 2024-05-28 | Richter Gedeon Nyrt | Improvement of affinity chromatography of immunoglobulins by using pre-capture flocculation |
| EP4025584A1 (en) * | 2019-09-06 | 2022-07-13 | Bia Separations D.O.O. | Compositions and methods for reducing chromatin content of biological preparations |
| US20230227496A1 (en) * | 2020-04-13 | 2023-07-20 | 3M Innovative Properties Company | Flow-through processes and devices for purifying a target molecule |
| SI3995196T1 (en) * | 2020-11-04 | 2023-10-30 | Sartorius Bia Separations D.O.O. | Purification process for lipid-membrane-enclosed complex assemblages |
| CN116472353A (en) | 2020-11-24 | 2023-07-21 | 赛多利斯比亚分离有限责任公司 | Improved affinity chromatography washing method |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE122054T1 (en) * | 1990-03-22 | 1995-05-15 | Biotest Pharma Gmbh | METHOD FOR PRODUCING AN INTRAVENOUSLY TOLERABLE IMMUNOGLOBULIN G PREPARATION. |
| FR2824568B1 (en) * | 2001-05-11 | 2004-04-09 | Lab Francais Du Fractionnement | PROCESS FOR THE PREPARATION OF HUMAN IMMUNOGLOBULIN CONCENTRATES FOR THERAPEUTIC USE |
| KR20050095605A (en) | 2003-01-09 | 2005-09-29 | 제넨테크, 인크. | Purification of polypeptides |
| US20040260066A1 (en) * | 2003-06-20 | 2004-12-23 | De Leon Juan Felipe | Method for purifying mixtures of immunoglobulin & albumin |
| US20070244305A1 (en) * | 2004-01-30 | 2007-10-18 | Suomen Punainen Risti Veripalvelu | Process for The Manufacture of Virus Safe Immunoglobulin |
| RU2337109C2 (en) * | 2004-02-27 | 2008-10-27 | Октафарма Аг | PREPARATION OF ANTIBODY IgG AND METHOD OF ITS PRODUCTION |
| JP2008500972A (en) * | 2004-05-14 | 2008-01-17 | キリンファーマ株式会社 | Immunoglobulin purification method |
| DE602008004747D1 (en) * | 2007-02-22 | 2011-03-10 | Baxter Int | PROCESS FOR PURIFYING HYDROPHOUS PROTEINS |
| JP5713379B2 (en) * | 2009-01-15 | 2015-05-07 | 株式会社プリベンテック | Extraction and purification method of recombinant proteins expressed in recombinant plants and difficult to extract |
| WO2010151632A1 (en) * | 2009-06-25 | 2010-12-29 | Bristol-Myers Squibb Company | Protein purifacation by caprylic acid (octanoic acid ) precipitation |
| SG10201801372YA (en) * | 2011-02-07 | 2018-04-27 | Cerenis Therapeutics Holding S A | Lipoprotein complexes and manufacturing and uses thereof |
| CN103717284B (en) * | 2011-06-08 | 2016-02-24 | 新加坡科技研究局 | By retraining common hydration chromatogram purification biological products |
| KR20150118103A (en) | 2013-02-06 | 2015-10-21 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | Protein purification methods |
| EP3107927A4 (en) | 2014-02-19 | 2017-08-30 | Agency For Science, Technology And Research | Fractionation method |
-
2014
- 2014-02-27 WO PCT/SG2014/000088 patent/WO2014133459A1/en active Application Filing
- 2014-02-27 SG SG11201505192RA patent/SG11201505192RA/en unknown
- 2014-02-27 EP EP14756552.7A patent/EP2961763A4/en not_active Withdrawn
- 2014-02-27 US US14/769,098 patent/US9994611B2/en not_active Expired - Fee Related
- 2014-02-27 KR KR1020157021655A patent/KR20150123796A/en not_active Application Discontinuation
- 2014-02-27 CN CN201480011131.8A patent/CN105189530B/en not_active Expired - Fee Related
- 2014-02-27 JP JP2015560141A patent/JP2016509068A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016509068A (en) | 2016-03-24 |
| EP2961763A1 (en) | 2016-01-06 |
| CN105189530B (en) | 2019-06-07 |
| US20160009762A1 (en) | 2016-01-14 |
| US9994611B2 (en) | 2018-06-12 |
| WO2014133459A1 (en) | 2014-09-04 |
| CN105189530A (en) | 2015-12-23 |
| EP2961763A4 (en) | 2016-10-12 |
| KR20150123796A (en) | 2015-11-04 |
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