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SG11201406855TA - Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy - Google Patents

Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy

Info

Publication number
SG11201406855TA
SG11201406855TA SG11201406855TA SG11201406855TA SG11201406855TA SG 11201406855T A SG11201406855T A SG 11201406855TA SG 11201406855T A SG11201406855T A SG 11201406855TA SG 11201406855T A SG11201406855T A SG 11201406855TA SG 11201406855T A SG11201406855T A SG 11201406855TA
Authority
SG
Singapore
Prior art keywords
gcc
susceptibility
test
same
antibody molecules
Prior art date
Application number
SG11201406855TA
Inventor
Helen Alison Frank
Alice A Mcdonald
Theresa L O'keefe
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of SG11201406855TA publication Critical patent/SG11201406855TA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
SG11201406855TA 2012-04-27 2013-04-27 Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy SG11201406855TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261639376P 2012-04-27 2012-04-27
PCT/US2013/038542 WO2013163633A1 (en) 2012-04-27 2013-04-27 Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy

Publications (1)

Publication Number Publication Date
SG11201406855TA true SG11201406855TA (en) 2014-11-27

Family

ID=49477498

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406855TA SG11201406855TA (en) 2012-04-27 2013-04-27 Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy

Country Status (41)

Country Link
US (3) US9000129B2 (en)
EP (1) EP2841575B1 (en)
JP (2) JP6472746B2 (en)
KR (1) KR102046435B1 (en)
CN (1) CN104395470B (en)
AR (1) AR090884A1 (en)
AU (1) AU2013251312B2 (en)
CA (1) CA2871614C (en)
CL (1) CL2014002911A1 (en)
CO (1) CO7280144A2 (en)
CR (1) CR20140497A (en)
CY (1) CY1122557T1 (en)
DK (1) DK2841575T3 (en)
DO (1) DOP2014000242A (en)
EA (1) EA034689B1 (en)
EC (1) ECSP14028523A (en)
ES (1) ES2749181T3 (en)
GE (1) GEP201706737B (en)
HK (1) HK1208049A1 (en)
HR (1) HRP20191690T1 (en)
HU (1) HUE046404T2 (en)
IL (1) IL235307B (en)
LT (1) LT2841575T (en)
MA (1) MA37569B1 (en)
ME (1) ME03560B (en)
MX (1) MX362020B (en)
MY (1) MY188442A (en)
NZ (1) NZ701601A (en)
PE (1) PE20142322A1 (en)
PH (1) PH12014502399A1 (en)
PL (1) PL2841575T3 (en)
PT (1) PT2841575T (en)
RS (1) RS59370B1 (en)
SA (1) SA113340502B1 (en)
SG (1) SG11201406855TA (en)
SI (1) SI2841575T1 (en)
TN (1) TN2014000454A1 (en)
TW (1) TWI631137B (en)
UA (1) UA117910C2 (en)
WO (1) WO2013163633A1 (en)
ZA (1) ZA201407723B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2774032C (en) 2009-10-23 2019-03-26 Millennium Pharmaceuticals, Inc. Anti-gcc antibody molecules and related compositions and methods
CA2928043A1 (en) * 2013-10-21 2015-04-30 The Centre For Drug Research And Development Anti-podocalyxin antibodies and methods of using the same
CA2936907C (en) 2014-02-14 2022-06-07 Arkansas Children's Hospital Research Institute, Inc. Acetaminophen protein adducts and methods of use thereof
JP6785239B2 (en) 2014-12-03 2020-11-18 バイオベンチャーズ・リミテッド・ライアビリティ・カンパニーＢｉｏＶｅｎｔｕｒｅｓ， ＬＬＣ Anti-acetaminophen antibody and acetaminophen protein adduct
CN109311994B (en) 2015-10-01 2022-06-07 药物研究及发展中心 Anti-podocalyxin antibodies and methods of use thereof
CN110268108B (en) 2016-12-12 2022-09-06 埃克切拉生物科学公司 Methods and systems for screening using microcapillary arrays
KR102080887B1 (en) * 2017-11-07 2020-02-24 고려대학교 산학협력단 Composition for diagnosing or prognosing lung cancer including exosome based gcc2 gene and protein
US11568657B2 (en) 2017-12-06 2023-01-31 Ventana Medical Systems, Inc. Method of storing and retrieving digital pathology analysis results
JP7197584B2 (en) * 2017-12-06 2022-12-27 ベンタナ メディカル システムズ， インコーポレイテッド Methods for storing and retrieving digital pathology analysis results
CN112996492A (en) * 2018-09-05 2021-06-18 阿姆斯特丹大学 Use of PDE11 or PDE2 inhibitors for the treatment of Parkinson's disease
WO2021205325A1 (en) * 2020-04-08 2021-10-14 Pfizer Inc. Anti-gucy2c antibodies and uses thereof
BR112022022030A2 (en) * 2020-06-02 2023-01-17 Teijin Pharma Ltd HUMANIZED ANTI-IGF-1 RECEPTOR ANTIBODY, NUCLEIC ACID MOLECULE, CLONING VECTOR OR EXPRESSION VECTOR, RECOMBINANT CELL, PROCESS FOR PRODUCING A HUMANIZED ANTI-IGF-1 RECEPTOR ANTIBODY, AND, PHARMACEUTICAL COMPOSITION
US20240059794A1 (en) * 2020-12-17 2024-02-22 Parasol Biotech Ltd. Gucy2c binding molecules and uses thereof
WO2024067762A1 (en) * 2022-09-28 2024-04-04 Nanjing Legend Biotech Co., Ltd. Antibody and chimeric antigen receptors targeting gcc and methods of use thereof
US20240165257A1 (en) 2022-11-01 2024-05-23 Heidelberg Pharma Research Gmbh Anti-gucy2c antibody and uses thereof
CN116535514B (en) * 2023-06-15 2024-02-02 上海斯丹赛生物技术有限公司 Anti-guanylate cyclase C antibodies and their use in cancer treatment

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237051A (en) 1990-12-06 1993-08-17 Vanderbilt University Purified enterotoxin receptor protein
AU681920B2 (en) 1993-10-26 1997-09-11 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
US5879656A (en) 1993-10-26 1999-03-09 Thomas Jefferson University Methods of treating metastatic colorectal cancer with ST receptor binding compounds
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
US5601990A (en) 1994-09-13 1997-02-11 Thomas Jefferson University Methods of diagnosing colorectal tumors and metastasis thereof
US5518888A (en) 1993-10-26 1996-05-21 Thomas Jefferson University ST receptor binding compounds and methods of using the same
US6455251B1 (en) 1994-09-13 2002-09-24 Thomas Jefferson University Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof
CA2254082C (en) 1996-05-03 2012-09-11 Thomas Jefferson University Metastatic colorectal cancer vaccine
US6602659B1 (en) 1996-05-03 2003-08-05 Thomas Jefferson University Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof
US6120995A (en) 1997-08-07 2000-09-19 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
US6696550B2 (en) 1998-07-23 2004-02-24 Millennium Pharmaceuticals, Inc. Humanized anti-CCR2 antibodies and methods of use therefor
US8092514B1 (en) 1998-11-16 2012-01-10 Boston Scientific Scimed, Inc. Stretchable anti-buckling coiled-sheet stent
US20040031072A1 (en) 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
JP2003535580A (en) 2000-03-27 2003-12-02 トーマス ジェファーソン ユニバーシティ High specificity marker detection
PE20020574A1 (en) 2000-12-06 2002-07-02 Wyeth Corp HUMANIZED ANTIBODIES THAT RECOGNIZE THE AMYLOID PEPTIDE BETA
ATE524195T1 (en) 2001-01-26 2011-09-15 Inhibitex Inc MONOCLONAL ANTIBODIES AGAINST CLFA PROTEIN AND METHOD FOR USE IN THE TREATMENT OR PREVENTION OF INFECTIONS
CN103641892B (en) 2001-03-29 2015-06-17 药物协和公司 Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis
NZ529494A (en) 2001-04-13 2005-08-26 Biogen Idec Inc Antibodies to VLA-1
AU2002361886A1 (en) 2001-12-28 2003-07-24 Abgenix, Inc. Antibodies against the muc18 antigen
WO2004024750A2 (en) 2002-09-13 2004-03-25 Dyax Corporation Cd44-binding ligands
DE10254601A1 (en) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Gene products differentially expressed in tumors and their use
US7304036B2 (en) 2003-01-28 2007-12-04 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US7371727B2 (en) 2003-01-28 2008-05-13 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US8206704B2 (en) 2003-02-10 2012-06-26 Thomas Jefferson University Use of GCC ligands
WO2004101790A1 (en) 2003-05-14 2004-11-25 Domantis Limited A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire
US7871610B2 (en) 2003-08-12 2011-01-18 Dyax Corp. Antibodies to Tie1 ectodomain
US8563682B2 (en) 2004-06-25 2013-10-22 Thomas Jefferson University Guanylylcyclase C ligands
KR101017301B1 (en) 2004-12-21 2011-02-28 메드임뮨 리미티드 Antibodies Directed to Angiopoietin-2 and Uses Thereof
AR056857A1 (en) 2005-12-30 2007-10-24 U3 Pharma Ag DIRECTED ANTIBODIES TO HER-3 (RECEIVER OF THE HUMAN EPIDERMAL GROWTH FACTOR-3) AND ITS USES
US8207295B2 (en) 2008-06-04 2012-06-26 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
RS53661B1 (en) 2007-08-10 2015-04-30 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human nerve growth factor
ES2593791T3 (en) * 2007-08-10 2016-12-13 Janssen Biotech, Inc. Immunoglobulin cleavage fragments used as disease indicators and binding binder
PT2220492E (en) * 2007-11-30 2011-12-16 Genentech Inc Vegf polymorphisms and anti-angiogenesis therapy
CA2760050A1 (en) 2008-05-13 2009-11-19 Thomas Jefferson University Guanylyl cyclase c qrt-pcr
ES2624828T3 (en) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
CA2745288A1 (en) * 2008-12-03 2010-06-10 Alisa Kabcenell Antibodies for guanylyl cyclase receptors
EP3266795A1 (en) * 2009-02-12 2018-01-10 Cell Signaling Technology, Inc. Method for detecting a fig-ros fusion polynucleotide
CN102333887B (en) 2009-02-25 2014-04-02 戴格努生命科学公司 Method for detecting metastasis of gi cancer
WO2010104035A1 (en) * 2009-03-12 2010-09-16 学校法人近畿大学 Method for predicting therapeutic efficacy of chemotherapy on non-small-cell lung cancer
WO2010147684A1 (en) 2009-06-15 2010-12-23 Thomas Jefferson University Compositions for and methods of activating guanylyl cyclase c
JP5955771B2 (en) 2009-10-22 2016-07-20 トーマス・ジェファーソン・ユニバーシティＴｈｏｍａｓ Ｊｅｆｆｅｒｓｏｎ Ｕｎｉｖｅｒｓｉｔｙ Cell-based anticancer composition and methods for making and using the same
CA2774032C (en) * 2009-10-23 2019-03-26 Millennium Pharmaceuticals, Inc. Anti-gcc antibody molecules and related compositions and methods
WO2011150454A1 (en) * 2010-06-01 2011-12-08 Monash University ANTIBODIES DIRECTED TO THE UNPROCESSED RECEPTOR TYROSINE KINASE c-MET
KR20140003393A (en) * 2010-08-13 2014-01-09 에프. 호프만-라 로슈 아게 Neuropilin as a biomarker for bevacizumab combination therapies
US20150086481A1 (en) 2011-07-28 2015-03-26 Memorial Sloan-Kettering Cancer Center Diagnosis and treatment of parkinson's disease
US9156915B2 (en) 2012-04-26 2015-10-13 Thomas Jefferson University Anti-GCC antibody molecules
TW201444577A (en) * 2013-02-28 2014-12-01 Millennium Pharm Inc Administration of an anti-GCC antibody-drug conjugate and a DNA damaging agent in the treatment of cancer

Also Published As

Publication number Publication date
HUE046404T2 (en) 2020-02-28
LT2841575T (en) 2019-10-10
AU2013251312B2 (en) 2018-03-22
CA2871614C (en) 2021-08-31
CN104395470B (en) 2018-02-06
PT2841575T (en) 2019-10-11
CL2014002911A1 (en) 2015-01-30
CA2871614A1 (en) 2013-10-31
ZA201407723B (en) 2019-01-30
MY188442A (en) 2021-12-09
US20160130344A1 (en) 2016-05-12
CR20140497A (en) 2015-02-10
HK1208049A1 (en) 2016-02-19
WO2013163633A1 (en) 2013-10-31
PH12014502399B1 (en) 2014-12-22
EP2841575A4 (en) 2016-06-15
CY1122557T1 (en) 2021-01-27
US9273146B1 (en) 2016-03-01
SA113340502B1 (en) 2015-09-17
UA117910C2 (en) 2018-10-25
PH12014502399A1 (en) 2014-12-22
AU2013251312A1 (en) 2014-10-30
ECSP14028523A (en) 2015-09-30
US9000129B2 (en) 2015-04-07
ME03560B (en) 2020-07-20
AR090884A1 (en) 2014-12-10
EA034689B1 (en) 2020-03-06
PE20142322A1 (en) 2015-01-25
CO7280144A2 (en) 2015-05-29
KR102046435B1 (en) 2019-11-19
MA37569B1 (en) 2020-08-31
TW201348258A (en) 2013-12-01
NZ701601A (en) 2016-09-30
EP2841575A1 (en) 2015-03-04
DK2841575T3 (en) 2019-09-23
IL235307A0 (en) 2014-12-31
JP2017131245A (en) 2017-08-03
SI2841575T1 (en) 2019-11-29
US20130287783A1 (en) 2013-10-31
TN2014000454A1 (en) 2016-03-30
JP6472746B2 (en) 2019-02-20
CN104395470A (en) 2015-03-04
PL2841575T3 (en) 2020-01-31
MX362020B (en) 2019-01-04
EA201491977A1 (en) 2015-04-30
DOP2014000242A (en) 2014-11-30
JP2015516985A (en) 2015-06-18
MX2014013081A (en) 2015-01-12
IL235307B (en) 2019-07-31
ES2749181T3 (en) 2020-03-19
GEP201706737B (en) 2017-09-25
TWI631137B (en) 2018-08-01
KR20150004882A (en) 2015-01-13
RS59370B1 (en) 2019-11-29
HRP20191690T1 (en) 2019-12-27
BR112014026742A2 (en) 2017-07-11
JP6517267B2 (en) 2019-05-22
EP2841575B1 (en) 2019-06-26

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