[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

SG10201913002QA - Methods for detecting aav - Google Patents

Methods for detecting aav

Info

Publication number
SG10201913002QA
SG10201913002QA SG10201913002QA SG10201913002QA SG10201913002QA SG 10201913002Q A SG10201913002Q A SG 10201913002QA SG 10201913002Q A SG10201913002Q A SG 10201913002QA SG 10201913002Q A SG10201913002Q A SG 10201913002QA SG 10201913002Q A SG10201913002Q A SG 10201913002QA
Authority
SG
Singapore
Prior art keywords
methods
aav
detecting
detecting aav
Prior art date
Application number
SG10201913002QA
Inventor
Xiaoying Jin
Catherine O'riordan
Lin Liu
Kate Zhang
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59762045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201913002Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SG10201913002QA publication Critical patent/SG10201913002QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14123—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/075—Adenoviridae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Record Carriers (AREA)
SG10201913002QA 2016-08-15 2017-08-14 Methods for detecting aav SG10201913002QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662375314P 2016-08-15 2016-08-15

Publications (1)

Publication Number Publication Date
SG10201913002QA true SG10201913002QA (en) 2020-03-30

Family

ID=59762045

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913002QA SG10201913002QA (en) 2016-08-15 2017-08-14 Methods for detecting aav
SG11201901221YA SG11201901221YA (en) 2016-08-15 2017-08-14 Methods for detecting aav

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201901221YA SG11201901221YA (en) 2016-08-15 2017-08-14 Methods for detecting aav

Country Status (23)

Country Link
US (2) US11698377B2 (en)
EP (2) EP3497207B1 (en)
JP (3) JP7021191B2 (en)
KR (3) KR20230078834A (en)
CN (2) CN110168080B (en)
AU (2) AU2017312951B2 (en)
BR (1) BR112019002934A2 (en)
CA (1) CA3033856A1 (en)
CL (2) CL2019000392A1 (en)
CR (1) CR20190127A (en)
CY (1) CY1124364T1 (en)
DK (1) DK3497207T3 (en)
ES (1) ES2863674T3 (en)
HU (1) HUE053747T2 (en)
IL (2) IL264819B2 (en)
MA (1) MA55748A (en)
MX (2) MX2019001938A (en)
PH (1) PH12019500316A1 (en)
SG (2) SG10201913002QA (en)
TN (1) TN2019000047A1 (en)
TW (2) TW202309068A (en)
WO (1) WO2018035059A1 (en)
ZA (2) ZA201900945B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201508026D0 (en) 2015-05-11 2015-06-24 Ucl Business Plc Capsid
CN110168080B (en) 2016-08-15 2024-05-31 建新公司 Methods of detecting AAV
JOP20190200A1 (en) 2017-02-28 2019-08-27 Univ Pennsylvania Compositions useful in treatment of spinal muscular atrophy
DK3589730T5 (en) * 2017-02-28 2024-09-02 Univ Pennsylvania CLADE F ADENO-ASSOCIATED VIRUS (AAV) VECTOR AND USE THEREOF
JP2021516046A (en) * 2018-02-27 2021-07-01 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア Novel adeno-associated virus (AAV) vector, AAV vector with reduced capsid deamidation, and its use
BR112020017278A2 (en) * 2018-02-27 2020-12-22 The Trustees Of The University Of Pennsylvania ADENOSOCIATED VIRUS VECTORS (AAV), AAV VECTORS HAVING REDUCED CAPSIDE DAMMATION AND USES FOR THE SAME
US20210010028A1 (en) * 2018-03-06 2021-01-14 Voyager Therapeutics, Inc. Insect cell manufactured partial self-complementary aav genomes
US11391707B2 (en) * 2018-07-27 2022-07-19 Waters Technologies Corporation Liquid chromatography/mass spectrometry methods for the analysis of polar molecules
JP7451497B2 (en) * 2018-08-21 2024-03-18 マサチューセッツ アイ アンド イヤー インファーマリー Compositions and methods for modulating adeno-associated virus transduction efficiency
SG11202103463RA (en) 2018-10-25 2021-05-28 Regeneron Pharma Methods for analysis of viral capsid protein composition
US11841352B2 (en) * 2019-07-31 2023-12-12 Thermo Finnigan Llc Determination and correction of retention time and mass/charge shifts in LC-MS experiments
EP4085255A1 (en) 2020-01-03 2022-11-09 Sarepta Therapeutics, Inc. Methods for analyzing aav capsid proteins
WO2021155137A1 (en) 2020-01-29 2021-08-05 Genzyme Corporation Modified adeno-associated viral capsid proteins for ocular gene therapy and methods of use thereof
CN111517359B (en) * 2020-04-23 2021-08-20 江南大学 Synthesis method of chiral copper sulfide super particle
RU2748540C1 (en) * 2021-02-08 2021-05-26 Автономная некоммерческая образовательная организация высшего образования "Сколковский институт науки и технологий" Method for detecting sars-cov-2 virus by mass spectrometry
US20220268783A1 (en) * 2021-02-19 2022-08-25 Waters Technologies Corporation Methods for peptide mapping of adeno-associated virus (aav) proteins
JPWO2022224965A1 (en) * 2021-04-20 2022-10-27
CA3225360A1 (en) * 2021-07-12 2023-01-19 Victoria COTHAM Online native mass spectrometry methods for assaying viral particles
WO2023287723A1 (en) * 2021-07-12 2023-01-19 Regeneron Pharmaceuticals, Inc. Methods for viral particle characterization using two-dimensional liquid chromatography-mass spectrometry
CN113552349B (en) * 2021-07-30 2022-07-19 上海勉亦生物科技有限公司 Detection method of AAV protein coat
JPWO2023132338A1 (en) * 2022-01-06 2023-07-13
WO2024186532A1 (en) * 2023-03-03 2024-09-12 Sartorius Bioanalytical Instruments, Inc. Methods for quantitating viral capsids

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540931A (en) 1989-03-03 1996-07-30 Charles W. Hewitt Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
US6204059B1 (en) * 1994-06-30 2001-03-20 University Of Pittsburgh AAV capsid vehicles for molecular transfer
WO1998010088A1 (en) 1996-09-06 1998-03-12 Trustees Of The University Of Pennsylvania An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
US6989264B2 (en) 1997-09-05 2006-01-24 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
US6566118B1 (en) 1997-09-05 2003-05-20 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
US6596535B1 (en) 1999-08-09 2003-07-22 Targeted Genetics Corporation Metabolically activated recombinant viral vectors and methods for the preparation and use
JP4860886B2 (en) 2000-06-01 2012-01-25 ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル Double-stranded parvovirus vector
US6723551B2 (en) 2001-11-09 2004-04-20 The United States Of America As Represented By The Department Of Health And Human Services Production of adeno-associated virus in insect cells
AU2002361573B2 (en) 2001-11-13 2008-06-12 The Trustees Of The University Of Pennsylvania A method of detecting and/or identifying ADENO-associated virus (AAV) sequences and isolating novel sequences identified thereby
DE60323078D1 (en) 2002-05-01 2008-10-02 Univ Florida IMPROVED RAAV EXPRESSION SYSTEMS FOR THE GENETIC MODIFICATION OF SPECIFIC CAPSID PROTEINS
EP1586107A2 (en) * 2002-11-22 2005-10-19 Caprion Pharmaceuticals, Inc. Constellation mapping and uses thereof
US7510872B2 (en) 2003-02-26 2009-03-31 Nationwide Children's Hospital Recombinant adeno-associated virus production
WO2004113494A2 (en) 2003-05-21 2004-12-29 Avigen, Inc. Methods for producing preparations of recombinant aav virions substantially free of empty capsids
EP1486567A1 (en) 2003-06-11 2004-12-15 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved adeno-associated virus (AAV) vector for gene therapy
US9441244B2 (en) 2003-06-30 2016-09-13 The Regents Of The University Of California Mutant adeno-associated virus virions and methods of use thereof
WO2006119432A2 (en) 2005-04-29 2006-11-09 The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services Isolation, cloning and characterization of new adeno-associated virus (aav) serotypes
ES2410133T3 (en) * 2005-10-20 2013-07-01 Uniqure Ip B.V. Enhanced VAA vectors produced in insect cells.
US7588772B2 (en) 2006-03-30 2009-09-15 Board Of Trustees Of The Leland Stamford Junior University AAV capsid library and AAV capsid proteins
US20110275529A1 (en) 2008-09-19 2011-11-10 Charite Universitatsmedizin Berlin Identification and characterisation of recombinant viral gene therapy vectors
WO2010093784A2 (en) * 2009-02-11 2010-08-19 The University Of North Carolina At Chapel Hill Modified virus vectors and methods of making and using the same
DK3444335T3 (en) 2009-06-16 2021-07-26 Genzyme Corp IMPROVED PROCEDURES FOR PURIFICATION OF RECOMBINANT AAV VECTORS
EP3514232A1 (en) 2010-04-23 2019-07-24 University of Massachusetts Cns targeting aav vectors and methods of use thereof
WO2012031245A1 (en) * 2010-09-03 2012-03-08 North Carolina Central University Biodegradable liquogel and ph sensitive nanocarriers
US8663624B2 (en) 2010-10-06 2014-03-04 The Regents Of The University Of California Adeno-associated virus virions with variant capsid and methods of use thereof
EP2675902B1 (en) 2011-02-17 2019-03-27 The Trustees Of The University Of Pennsylvania Compositions and methods for altering tissue specificity and improving aav9-mediated gene transfer
US9169299B2 (en) 2011-08-24 2015-10-27 The Board Of Trustees Of The Leleand Stanford Junior University AAV capsid proteins for nucleic acid transfer
KR102063483B1 (en) * 2012-04-18 2020-01-08 더 칠드런스 호스피탈 오브 필라델피아 Composition and methods for highly efficient gene transfer using aav capsid variants
US20140017716A1 (en) * 2012-07-11 2014-01-16 Siscapa Assay Technologies, Inc. Proteolytic digestion kit with dried reagents
GB201401707D0 (en) * 2014-01-31 2014-03-19 Sec Dep For Health The Adeno-associated viral vectors
PT3117005T (en) 2014-03-10 2024-07-30 Uniqure Ip Bv Further improved aav vectors produced in insect cells
CN110168080B (en) 2016-08-15 2024-05-31 建新公司 Methods of detecting AAV

Also Published As

Publication number Publication date
TN2019000047A1 (en) 2020-07-15
EP3851449A1 (en) 2021-07-21
US20210041451A1 (en) 2021-02-11
US20240044910A1 (en) 2024-02-08
AU2024200349A1 (en) 2024-02-08
CL2019000392A1 (en) 2019-05-10
AU2017312951B2 (en) 2024-02-08
JP2019533803A (en) 2019-11-21
TW202309068A (en) 2023-03-01
JP2024023460A (en) 2024-02-21
KR20220107327A (en) 2022-08-02
DK3497207T3 (en) 2021-03-22
RU2019107207A3 (en) 2021-04-29
HUE053747T2 (en) 2021-07-28
ES2863674T3 (en) 2021-10-11
JP7021191B2 (en) 2022-02-16
US11698377B2 (en) 2023-07-11
IL264819B1 (en) 2024-06-01
MX2023009081A (en) 2023-08-08
JP2022064980A (en) 2022-04-26
CN118688363A (en) 2024-09-24
CR20190127A (en) 2019-06-25
IL264819A (en) 2019-04-30
ZA202101002B (en) 2024-07-31
RU2019107207A (en) 2020-09-15
CL2019002912A1 (en) 2020-03-06
BR112019002934A2 (en) 2019-05-14
IL312792A (en) 2024-07-01
KR20190039253A (en) 2019-04-10
TW201825898A (en) 2018-07-16
AU2017312951A1 (en) 2019-04-04
KR20230078834A (en) 2023-06-02
WO2018035059A9 (en) 2019-03-14
CY1124364T1 (en) 2022-07-22
CA3033856A1 (en) 2018-02-22
PH12019500316A1 (en) 2019-08-05
CN110168080B (en) 2024-05-31
MX2019001938A (en) 2019-07-04
CN110168080A (en) 2019-08-23
EP3497207A1 (en) 2019-06-19
KR102538037B1 (en) 2023-05-30
TWI781953B (en) 2022-11-01
US12123880B2 (en) 2024-10-22
ZA201900945B (en) 2021-06-30
KR102425289B1 (en) 2022-07-27
EP3497207B1 (en) 2021-01-06
WO2018035059A1 (en) 2018-02-22
SG11201901221YA (en) 2019-03-28
IL264819B2 (en) 2024-10-01
MA55748A (en) 2022-03-02

Similar Documents

Publication Publication Date Title
ZA201900945B (en) Methods for detecting aav
DK3478217T3 (en) Historisk scanningsreference for intraorale scanninger
HK1251292A1 (en) Tyre condition analysis
HK1222906A1 (en) Vehicle-borne inspection system
GB201403489D0 (en) Biomarkers for endometriosis
HK1222928A1 (en) Position detecting unit
GB2537562B (en) Measurement system
EP3096148C0 (en) Pipetting device
PL3135381T3 (en) Centrifuge
PL3183174T3 (en) Pipetting system
GB201405203D0 (en) Detecting apparatus
GB201411515D0 (en) Separations
GB201503692D0 (en) Vehicle detection apparatus
PT3391016T (en) Sampler
DK3189327T3 (en) Ph-sensor for metaloxid
GB201621664D0 (en) Measurement system
IL252363A0 (en) Molecule detecting system
IL247996B (en) Method for detecting protein modifications
GB201510909D0 (en) Detection apparatus
GB201502226D0 (en) AH-7921 detection
EP3170115A4 (en) Determining terms for security test
GB2572279B (en) Detecting faults
ZA201800597B (en) Age determination device
GB201707731D0 (en) Detection system
EP3099576A4 (en) Ice detecting apparatus