SG10201804238TA - Enhanced deposition of chromogens utilizing pyrimidine analogs - Google Patents
Enhanced deposition of chromogens utilizing pyrimidine analogsInfo
- Publication number
- SG10201804238TA SG10201804238TA SG10201804238TA SG10201804238TA SG10201804238TA SG 10201804238T A SG10201804238T A SG 10201804238TA SG 10201804238T A SG10201804238T A SG 10201804238TA SG 10201804238T A SG10201804238T A SG 10201804238TA SG 10201804238T A SG10201804238T A SG 10201804238TA
- Authority
- SG
- Singapore
- Prior art keywords
- compositions
- chromogens
- moiety
- heteroatom
- deposition
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061460349P | 2010-12-30 | 2010-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201804238TA true SG10201804238TA (en) | 2018-06-28 |
Family
ID=45554795
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201804238TA SG10201804238TA (en) | 2010-12-30 | 2011-12-28 | Enhanced deposition of chromogens utilizing pyrimidine analogs |
| SG2013040589A SG190892A1 (en) | 2010-12-30 | 2011-12-28 | Enhanced deposition of chromogens utilizing pyrimidine analogs |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013040589A SG190892A1 (en) | 2010-12-30 | 2011-12-28 | Enhanced deposition of chromogens utilizing pyrimidine analogs |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8871442B2 (fr) |
| EP (2) | EP2659000B1 (fr) |
| JP (2) | JP5815046B2 (fr) |
| KR (1) | KR101554795B1 (fr) |
| CN (1) | CN103282516B (fr) |
| AU (2) | AU2011352251B2 (fr) |
| BR (1) | BR112013014360B8 (fr) |
| CA (2) | CA2817374C (fr) |
| DK (2) | DK3088534T3 (fr) |
| ES (2) | ES2689593T3 (fr) |
| HK (1) | HK1185634A1 (fr) |
| IL (1) | IL226479A (fr) |
| SG (2) | SG10201804238TA (fr) |
| WO (1) | WO2012092322A1 (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2659000B1 (fr) * | 2010-12-30 | 2016-08-10 | Ventana Medical Systems, Inc. | Dépôt optimisé de chromogènes utilisant des analogues de la pyrimidine |
| AU2013211666B2 (en) | 2012-01-23 | 2015-09-03 | Ventana Medical Systems, Inc | Polymer stabilization of chromogen solutions |
| AU2013240090B2 (en) | 2012-03-27 | 2017-01-05 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| WO2014046730A1 (fr) | 2012-09-24 | 2014-03-27 | Ventana Medical Systems, Inc. | Méthode d'identification d'un cancer du poumon autre qu'à petites cellules (nsclc) réagissant à un traitement au moyen de la kinase du lymphome anaplasique (alk) comme marqueur |
| KR102189659B1 (ko) * | 2013-02-28 | 2020-12-11 | 가부시키가이샤 니찌레이 바이오사이언스 | 표지 효소를 사용한 염색용 dab 함유 기질 키트 |
| ES2804300T3 (es) | 2013-03-12 | 2021-02-05 | Ventana Med Syst Inc | Microscopía mejorada digitalmente para histología multiplexada |
| WO2015028382A1 (fr) | 2013-08-28 | 2015-03-05 | Ventana Medical Systems, Inc. | Essai immunohistochimique pour la détection de cd3 et cd16 |
| AU2015220750B2 (en) | 2014-02-24 | 2020-04-16 | Ventana Medical Systems, Inc. | Quinone methide analog signal amplification |
| CN107923915B (zh) | 2015-08-28 | 2021-05-04 | 文塔纳医疗系统公司 | 使用经掩蔽的半抗原在福尔马林固定石蜡包埋的组织中的蛋白质邻近测定 |
| US10718694B2 (en) * | 2016-04-18 | 2020-07-21 | Diagnostic Biosystems | Counterstains for a biological sample |
| WO2018002016A1 (fr) | 2016-06-28 | 2018-01-04 | Ventana Medical Systems, Inc. | Application de la chimie clic pour l'amplification de signaux dans des dosages ihc et ish |
| EP3475701B1 (fr) * | 2016-06-28 | 2023-02-22 | Ventana Medical Systems, Inc. | Nouvelles couleurs pour la coloration chromogène de type marquage ihc et ish à base de conjugués multicolorants méthide-tyramide de quinone |
| CN110785654A (zh) | 2017-06-28 | 2020-02-11 | 文塔纳医疗系统公司 | 系统级校准 |
| CN113423698A (zh) | 2018-09-20 | 2021-09-21 | 文塔纳医疗系统公司 | 基于香豆素的交联剂 |
| JP2020071152A (ja) | 2018-10-31 | 2020-05-07 | ソニー株式会社 | 免疫染色方法、免疫染色システム、および免疫染色キット |
| CN115989221A (zh) | 2020-08-28 | 2023-04-18 | 文塔纳医疗系统公司 | 包含可检测部分的缀合物 |
| WO2022066512A1 (fr) | 2020-09-22 | 2022-03-31 | Ventana Medical Systems, Inc. | Prédiction de la réponse à des thérapies dirigées vers le récepteur du facteur de croissance épidermique par utilisation d'épiréguline et d'amphiréguline |
| JP2024504944A (ja) | 2021-01-15 | 2024-02-02 | ヴェンタナ メディカル システムズ， インク． | 保存安定なケージドハプテン |
| CN116868054A (zh) | 2021-01-25 | 2023-10-10 | 文塔纳医疗系统公司 | 包括用一个或多个可检测部分标记的一种或多种生物标志物的染色生物学样本 |
| EP4326736A1 (fr) | 2021-04-18 | 2024-02-28 | Ventana Medical Systems, Inc. | Coloration de marqueur morphologique |
| WO2024137817A1 (fr) | 2022-12-23 | 2024-06-27 | Ventana Medical Systems, Inc. | Matériaux et procédés d'évaluation de composants de machinerie de présentation antigénique et leurs utilisations |
| WO2025014787A1 (fr) | 2023-07-07 | 2025-01-16 | Ventana Medical Systems, Inc. | Dosage d'immunohistochimie triplex à fond clair pour évaluer la colocalisation des biomarqueurs er, pr et ki-67 dans des cellules |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1564604A (en) | 1925-06-12 | 1925-12-08 | Chas S Hodges | Water wheel |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| US4318984A (en) * | 1979-11-13 | 1982-03-09 | Miles Laboratories, Inc. | Stabilized composition, test device, and method for detecting the presence of a sugar in a test sample |
| GB8713951D0 (en) * | 1987-06-15 | 1987-07-22 | Dewar M H | Enhanced chemiluminescent reaction |
| WO1990003370A1 (fr) * | 1988-09-28 | 1990-04-05 | Microprobe Corporation | DERIVES DE PYRAZOLO[3,4-d]PYRIMIDINE |
| US5225325A (en) * | 1990-03-02 | 1993-07-06 | Ventana Medical Systems, Inc. | Immunohistochemical staining method and reagents therefor |
| US5595707A (en) | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
| DE69334258D1 (de) | 1992-08-21 | 2009-02-26 | Univ Bruxelles | Immunoglobuline ohne Leichtkette |
| US6005079A (en) | 1992-08-21 | 1999-12-21 | Vrije Universiteit Brussels | Immunoglobulins devoid of light chains |
| GB9306888D0 (en) * | 1993-04-01 | 1993-05-26 | Kricka Larry J | Chemiluminescent enhancers |
| JPH07308200A (ja) * | 1994-05-16 | 1995-11-28 | Konica Corp | ペルオキシダーゼ様物質の活性または酸化性物質の検出及び測定のための組成物並びに測定方法 |
| KR0164072B1 (ko) | 1995-11-13 | 1999-02-01 | 김주용 | 반도체 소자의 얕은 접합 형성방법 |
| AU4980097A (en) * | 1996-10-21 | 1998-05-15 | University Of Iowa Research Foundation, The | Efficient synthesis of nucleosides |
| US5866366A (en) | 1997-07-01 | 1999-02-02 | Smithkline Beecham Corporation | gidB |
| US6582962B1 (en) | 1998-02-27 | 2003-06-24 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| ES2354598T3 (es) | 1998-02-27 | 2011-03-16 | Ventana Medical Systems, Inc. | Aparato de patología molecular automatizado que tiene calefactores de portaobjetos independientes. |
| US20030211630A1 (en) | 1998-02-27 | 2003-11-13 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| DE19834938C2 (de) | 1998-07-29 | 2000-07-20 | Coty Bv | Verfahren zur kosmetischen Bräunungsbestimmung einer Selbstbräunungszusammensetzung und Test-Kit |
| US6372937B1 (en) | 1998-11-09 | 2002-04-16 | Mark Norman Bobrow | Enhanced catalyzed reporter deposition |
| US6355443B1 (en) * | 1999-03-17 | 2002-03-12 | Mark Norman Bobrow | 4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system |
| US6649138B2 (en) | 2000-10-13 | 2003-11-18 | Quantum Dot Corporation | Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media |
| US20020076732A1 (en) | 2000-12-15 | 2002-06-20 | Kaplan David R. | Methods for detecting an analyte of interest using catalyzed reporter deposition of tyramide |
| US20020083888A1 (en) | 2000-12-28 | 2002-07-04 | Zehnder Donald A. | Flow synthesis of quantum dot nanocrystals |
| US6670113B2 (en) | 2001-03-30 | 2003-12-30 | Nanoprobes | Enzymatic deposition and alteration of metals |
| US6617125B2 (en) * | 2001-06-29 | 2003-09-09 | Perkinelmer Life Sciences, Inc. | Compositions for enhanced catalyzed reporter deposition |
| EP2218762A3 (fr) | 2001-07-20 | 2010-09-29 | Life Technologies Corporation | Nanoparticules luminescentes et leurs procédés de préparation |
| US7642064B2 (en) | 2003-06-24 | 2010-01-05 | Ventana Medical Systems, Inc. | Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest |
| CA2530287C (fr) | 2003-06-24 | 2012-06-19 | Ventana Medical Systems, Inc. | Depot de metal catalyse par une enzyme pour la detection in situ amelioree d'epitopes immunohistochimiques et de sequences d'acides nucleiques |
| EP2659000B1 (fr) * | 2010-12-30 | 2016-08-10 | Ventana Medical Systems, Inc. | Dépôt optimisé de chromogènes utilisant des analogues de la pyrimidine |
-
2011
- 2011-12-28 EP EP11813853.6A patent/EP2659000B1/fr active Active
- 2011-12-28 ES ES16161377.3T patent/ES2689593T3/es active Active
- 2011-12-28 JP JP2013547631A patent/JP5815046B2/ja active Active
- 2011-12-28 WO PCT/US2011/067481 patent/WO2012092322A1/fr active Application Filing
- 2011-12-28 SG SG10201804238TA patent/SG10201804238TA/en unknown
- 2011-12-28 ES ES11813853.6T patent/ES2593464T3/es active Active
- 2011-12-28 EP EP16161377.3A patent/EP3088534B1/fr active Active
- 2011-12-28 DK DK16161377.3T patent/DK3088534T3/en active
- 2011-12-28 DK DK11813853.6T patent/DK2659000T3/en active
- 2011-12-28 CA CA2817374A patent/CA2817374C/fr active Active
- 2011-12-28 SG SG2013040589A patent/SG190892A1/en unknown
- 2011-12-28 BR BR112013014360A patent/BR112013014360B8/pt active IP Right Grant
- 2011-12-28 AU AU2011352251A patent/AU2011352251B2/en active Active
- 2011-12-28 KR KR1020137016695A patent/KR101554795B1/ko active IP Right Grant
- 2011-12-28 US US13/339,066 patent/US8871442B2/en active Active
- 2011-12-28 CA CA3007179A patent/CA3007179C/fr active Active
- 2011-12-28 CN CN201180062801.5A patent/CN103282516B/zh active Active
-
2013
- 2013-05-21 IL IL226479A patent/IL226479A/en active IP Right Grant
- 2013-11-20 HK HK13112956.2A patent/HK1185634A1/xx unknown
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2014
- 2014-10-06 US US14/507,447 patent/US9435795B2/en active Active
-
2015
- 2015-06-17 JP JP2015122090A patent/JP6130438B2/ja active Active
- 2015-07-30 AU AU2015207891A patent/AU2015207891B2/en active Active
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