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SG10201406572TA - Yeast strains for protein production - Google Patents

Yeast strains for protein production

Info

Publication number
SG10201406572TA
SG10201406572TA SG10201406572TA SG10201406572TA SG10201406572TA SG 10201406572T A SG10201406572T A SG 10201406572TA SG 10201406572T A SG10201406572T A SG 10201406572TA SG 10201406572T A SG10201406572T A SG 10201406572TA SG 10201406572T A SG10201406572T A SG 10201406572TA
Authority
SG
Singapore
Prior art keywords
protein production
yeast strains
strains
yeast
protein
Prior art date
Application number
SG10201406572TA
Inventor
Juergen Nett
Original Assignee
Glycofi Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycofi Inc filed Critical Glycofi Inc
Publication of SG10201406572TA publication Critical patent/SG10201406572TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/102Plasmid DNA for yeast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01021Phosphoribosylaminoimidazole carboxylase (4.1.1.21)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG10201406572TA 2007-12-19 2008-12-15 Yeast strains for protein production SG10201406572TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US824207P 2007-12-19 2007-12-19

Publications (1)

Publication Number Publication Date
SG10201406572TA true SG10201406572TA (en) 2014-11-27

Family

ID=40824940

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201406572TA SG10201406572TA (en) 2007-12-19 2008-12-15 Yeast strains for protein production

Country Status (8)

Country Link
US (2) US9133464B2 (en)
EP (1) EP2235198B1 (en)
JP (3) JP5960947B2 (en)
CN (1) CN101903531B (en)
AU (1) AU2008343972B2 (en)
CA (1) CA2705925C (en)
SG (1) SG10201406572TA (en)
WO (1) WO2009085135A2 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101903531B (en) 2007-12-19 2013-09-18 格利科菲公司 Yeast strains for protein production
US8067339B2 (en) 2008-07-09 2011-11-29 Merck Sharp & Dohme Corp. Surface display of whole antibodies in eukaryotes
EP2324121B1 (en) 2008-08-12 2012-11-07 GlycoFi, Inc. Improved vectors and yeast strains for protein production: ca2+ atpase overexpression
US9139632B2 (en) 2009-10-16 2015-09-22 Merck Sharp & Dohme Corp. Method for producing proteins in Pichia pastoris that lack detectable cross binding activity to antibodies against host cell antigens
US8715963B2 (en) 2010-02-24 2014-05-06 Merck Sharp & Dohme Corp. Method for increasing N-glycosylation site occupancy on therapeutic glycoproteins produced in Pichia pastoris
WO2011161208A1 (en) * 2010-06-25 2011-12-29 Novozymes A/S Polynucleotides having promoter activity
EP2585602A1 (en) * 2010-06-25 2013-05-01 Novozymes A/S Polynucleotides having promoter activity
KR101508635B1 (en) 2012-10-12 2015-04-07 한국생명공학연구원 Method for genome-wide random mutagenesis
EP2925345B1 (en) 2012-12-03 2018-09-05 Merck Sharp & Dohme Corp. Method for making o-glycosylated carboxy terminal portion (ctp) peptide-based insulin and insulin analogues
US9944689B2 (en) 2013-03-07 2018-04-17 The General Hospital Corporation Human CTLA4 mutants and use thereof
JP7138425B2 (en) * 2016-10-26 2022-09-16 キッコーマン株式会社 Method for transforming filamentous fungi
JP7227162B2 (en) 2017-06-06 2023-02-21 ザイマージェン インコーポレイテッド HTP Genome Engineering Platform for Improving Fungal Strains
KR20210018219A (en) 2018-06-06 2021-02-17 지머젠 인코포레이티드 Modification of genes involved in signaling to control fungal morphology during fermentation and production
WO2020172344A1 (en) 2019-02-19 2020-08-27 The Regents Of The University Of Colorado, A Body Corporate Bispecific immunotoxins targeting human cd25+ccr4+ tumors and regulatory t-cells
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
CN112398533B (en) * 2020-11-04 2023-06-27 中国科学院半导体研究所 Rapid focusing, transmitting and receiving integrated antenna and rapid focusing method
CN112226373B (en) * 2020-12-07 2021-04-20 中国科学院天津工业生物技术研究所 Strain for producing protein and application thereof

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US5584039A (en) 1993-11-08 1996-12-10 International Business Machines Corporation System for coordinating execution of multiple concurrent channel programs without host processor involvement using suspend and resume commands to control data transfer between I/O devices
FR2724182B1 (en) * 1994-09-02 1996-12-13 Pasteur Institut OBTAINING A RECOMBINANT MONOCLONAL ANTIBODY FROM A HUMAN ANTI-RHESUS D MONOCLONAL ANTIBODY, ITS PRODUCTION IN INSECT CELLS, AND USES THEREOF
AU712650B2 (en) * 1995-11-09 1999-11-11 Zymogenetics Inc. Compositions and methods for producing heterologous polypeptides in pichia methanolica
AU718510B2 (en) * 1996-07-17 2000-04-13 Zymogenetics Inc. Transformation of pichia methanolica
AU749453B2 (en) 1997-06-25 2002-06-27 Bristol-Myers Squibb Company D-amino acid oxidase promoter from T. variabilis
AU2030000A (en) * 1998-11-25 2000-06-13 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors
US6232074B1 (en) * 1999-12-10 2001-05-15 Complegen, Inc. Functional gene array in yeast
ATE438722T1 (en) * 2000-05-17 2009-08-15 Mitsubishi Tanabe Pharma Corp METHOD FOR PRODUCING PROTEINS WITH THE REDUCTION OF MANNOSE PHOSPHATE IN THE SUGAR CHAIN AND GLYCOPROTEIN PRODUCED THEREFROM
WO2001090393A1 (en) * 2000-05-24 2001-11-29 Novozymes A/S Method for increasing gene copy number in a host cell and resulting host cell
US7449308B2 (en) 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US7795002B2 (en) 2000-06-28 2010-09-14 Glycofi, Inc. Production of galactosylated glycoproteins in lower eukaryotes
ATE440959T1 (en) 2000-06-28 2009-09-15 Glycofi Inc METHOD FOR PRODUCING MODIFIED GLYCOPROTEINS
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US7700322B2 (en) * 2003-10-31 2010-04-20 Novozymes A/S Method for stable gene-amplification in a bacterial host cell
US7479389B2 (en) 2004-03-02 2009-01-20 Glycofi, Inc. ARG1, ARG2, ARG3, HIS1, HIS2, HIS5, HIS6 genes and methods for stable genetic integration
CA2598792A1 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
US20060252096A1 (en) 2005-04-26 2006-11-09 Glycofi, Inc. Single chain antibody with cleavable linker
US7226207B2 (en) 2005-09-09 2007-06-05 Feldmeier Robert H Temperature gauge for use with sanitary conduit
US20070277282A1 (en) 2006-05-17 2007-12-06 Art Sheppell Support for prevention of decubitus ulcers
CA2651456A1 (en) * 2006-05-19 2007-11-29 Glycofi, Inc. Recombinant vectors
CA2652578A1 (en) 2006-05-19 2007-11-29 Glycofi, Inc. Erythropoietin compositions
WO2007136685A2 (en) 2006-05-19 2007-11-29 Sangamo Biosciences, Inc. Methods and compositions for inactivation of dihydrofolate reductase
ATE530653T1 (en) * 2006-11-03 2011-11-15 Leibniz Inst Fuer Pflanzengenetik Und Kulturpflanzenforschung Ipk EXPRESSION VECTORS FOR MULTIPLE GENE INTEGRATION AND OVEREXPRESSION OF HOMOLOGUE AND HETEROLOGUE PROTEINS IN YEAST OF THE GENUS ARXULA
CN101903531B (en) 2007-12-19 2013-09-18 格利科菲公司 Yeast strains for protein production

Also Published As

Publication number Publication date
JP6646020B2 (en) 2020-02-14
CA2705925A1 (en) 2009-07-09
JP2011507512A (en) 2011-03-10
CN101903531B (en) 2013-09-18
CA2705925C (en) 2019-03-12
EP2235198A2 (en) 2010-10-06
US9133464B2 (en) 2015-09-15
JP2018033450A (en) 2018-03-08
WO2009085135A3 (en) 2009-12-30
EP2235198A4 (en) 2011-01-05
US20100279348A1 (en) 2010-11-04
AU2008343972A1 (en) 2009-07-09
US20150361438A1 (en) 2015-12-17
JP2016165300A (en) 2016-09-15
EP2235198B1 (en) 2018-08-29
WO2009085135A2 (en) 2009-07-09
JP5960947B2 (en) 2016-08-02
CN101903531A (en) 2010-12-01
US10059952B2 (en) 2018-08-28
AU2008343972B2 (en) 2014-07-03

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