SG10201406420XA - Antiproliferative agent - Google Patents
Antiproliferative agentInfo
- Publication number
- SG10201406420XA SG10201406420XA SG10201406420XA SG10201406420XA SG10201406420XA SG 10201406420X A SG10201406420X A SG 10201406420XA SG 10201406420X A SG10201406420X A SG 10201406420XA SG 10201406420X A SG10201406420X A SG 10201406420XA SG 10201406420X A SG10201406420X A SG 10201406420XA
- Authority
- SG
- Singapore
- Prior art keywords
- antiproliferative agent
- antiproliferative
- agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/50—Biochemical production, i.e. in a transformed host cell
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25148509P | 2009-10-14 | 2009-10-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201406420XA true SG10201406420XA (en) | 2014-11-27 |
Family
ID=43876362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201406420XA SG10201406420XA (en) | 2009-10-14 | 2010-10-14 | Antiproliferative agent |
Country Status (4)
Country | Link |
---|---|
US (2) | US20120207770A1 (en) |
EP (1) | EP2488640B1 (en) |
SG (1) | SG10201406420XA (en) |
WO (1) | WO2011046515A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013022406A1 (en) * | 2011-08-08 | 2013-02-14 | Nanyang Technological University | Angiopoietin-like 4 and its use in modulating cell leakiness |
CN104768972B (en) * | 2012-08-14 | 2019-12-06 | 南洋理工大学 | Angiopoietin-like 4 antibodies and methods of use thereof in cancer treatment |
GB201301313D0 (en) | 2013-01-25 | 2013-03-06 | Univ Singapore | Respiratory Tract Infections |
BR112017002173B1 (en) | 2014-08-07 | 2023-11-21 | Novartis Ag | Isolated anti-angptl4 antibody, or antigen-binding fragment thereof, its use, and pharmaceutical composition |
TW201613977A (en) | 2014-08-07 | 2016-04-16 | Novartis Ag | Angiopoetin-like 4 (ANGPTL4) antibodies and methods of use |
CA3117750A1 (en) * | 2018-11-13 | 2020-05-22 | Lipigon Pharmaceuticals Ab | Angptl4 oligonucleotides influencing the regulation of the fatty acid metabolism |
US20220296681A1 (en) * | 2019-08-07 | 2022-09-22 | Deutsches Krebsforschungszentrum | Inhibition of metastasis development by nangptl-4 |
WO2021119019A1 (en) | 2019-12-09 | 2021-06-17 | Empirico Inc. | Oligonucleotides for treatment of angiopoietin like 4 (angptl4) related diseases |
CN115485297A (en) * | 2020-04-27 | 2022-12-16 | 南洋理工大学 | Humanized monoclonal antibodies against cANGPTL4 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4180646A (en) | 1975-01-28 | 1979-12-25 | Alza Corporation | Novel orthoester polymers and orthocarbonate polymers |
US4093709A (en) | 1975-01-28 | 1978-06-06 | Alza Corporation | Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) |
US4131648A (en) | 1975-01-28 | 1978-12-26 | Alza Corporation | Structured orthoester and orthocarbonate drug delivery devices |
US4079038A (en) | 1976-03-05 | 1978-03-14 | Alza Corporation | Poly(carbonates) |
FR2413974A1 (en) | 1978-01-06 | 1979-08-03 | David Bernard | DRYER FOR SCREEN-PRINTED SHEETS |
US4304767A (en) | 1980-05-15 | 1981-12-08 | Sri International | Polymers of di- (and higher functionality) ketene acetals and polyols |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
US4946931A (en) | 1989-06-14 | 1990-08-07 | Pharmaceutical Delivery Systems, Inc. | Polymers containing carboxy-ortho ester and ortho ester linkages |
WO1991000360A1 (en) | 1989-06-29 | 1991-01-10 | Medarex, Inc. | Bispecific reagents for aids therapy |
AU8295491A (en) | 1990-06-29 | 1992-01-23 | Biosource Technologies Incorporated | Melanin production by transformed microorganisms |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
DK0814159T3 (en) | 1990-08-29 | 2005-10-24 | Genpharm Int | Transgenic, non-human animals capable of forming heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US6413536B1 (en) | 1995-06-07 | 2002-07-02 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system and medical or surgical device |
US5968543A (en) | 1996-01-05 | 1999-10-19 | Advanced Polymer Systems, Inc. | Polymers with controlled physical state and bioerodibility |
AU6526100A (en) | 1999-08-06 | 2001-03-05 | Board Of Regents, The University Of Texas System | Drug releasing biodegradable fiber implant |
US6613355B2 (en) | 2000-05-11 | 2003-09-02 | A.P. Pharma, Inc. | Semi-solid delivery vehicle and pharmaceutical compositions |
US6524606B1 (en) | 2001-11-16 | 2003-02-25 | Ap Pharma, Inc. | Bioerodible polyorthoesters containing amine groups |
US20060019284A1 (en) * | 2004-06-30 | 2006-01-26 | Fei Huang | Identification of polynucleotides for predicting activity of compounds that interact with and/or modulate protein tyrosine kinases and/or protein tyrosine kinase pathways in lung cancer cells |
EP1781698B1 (en) * | 2004-07-20 | 2016-07-06 | Genentech, Inc. | Compositions and methods of using angiopoietin-like 4 protein |
ES2339789T3 (en) * | 2004-07-20 | 2010-05-25 | Genentech, Inc. | PROTEIN 4 INHIBITORS OF ANGIOPOYETINE TYPE, COMBINATIONS AND ITS USE. |
US20060031945A1 (en) * | 2004-08-06 | 2006-02-09 | Yu Shen | Inducible expression systems for modulating the expression of target genes in eukaryotic cells and non-human animals |
WO2006044779A1 (en) * | 2004-10-14 | 2006-04-27 | Northwestern University | Detection and treatment of renal cancer |
BRPI0606432A2 (en) * | 2005-01-07 | 2009-06-30 | Lexicon Pharmaceuticals Inc | monoclonal antibodies to angptl4 |
WO2013022406A1 (en) * | 2011-08-08 | 2013-02-14 | Nanyang Technological University | Angiopoietin-like 4 and its use in modulating cell leakiness |
-
2010
- 2010-10-14 WO PCT/SG2010/000392 patent/WO2011046515A1/en active Application Filing
- 2010-10-14 EP EP10823705.8A patent/EP2488640B1/en active Active
- 2010-10-14 US US13/501,768 patent/US20120207770A1/en not_active Abandoned
- 2010-10-14 SG SG10201406420XA patent/SG10201406420XA/en unknown
-
2015
- 2015-01-06 US US14/590,397 patent/US10087447B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US10087447B2 (en) | 2018-10-02 |
EP2488640A4 (en) | 2014-01-01 |
US20120207770A1 (en) | 2012-08-16 |
WO2011046515A1 (en) | 2011-04-21 |
EP2488640A1 (en) | 2012-08-22 |
EP2488640B1 (en) | 2018-09-26 |
US20160053268A1 (en) | 2016-02-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3023438T3 (en) | Anti-gitr-antistoffer | |
DK2457337T3 (en) | Specialtilpasset impuls-burst | |
EP2462514A4 (en) | Greenbooks | |
EP2515891A4 (en) | 3-keto-n-propargyl-1-aminoindan | |
IL220526A0 (en) | Kokumi-imparting agent | |
EP2478768A4 (en) | Anti-plant-virus agent | |
IL220527A0 (en) | Kokumi-imparting agent | |
SG10201406420XA (en) | Antiproliferative agent | |
EP2519921A4 (en) | Call-tracking | |
PL2228278T3 (en) | Wagon | |
DK2464943T3 (en) | Systemintegration | |
GB0920846D0 (en) | Defenin inducing agent | |
PL2272348T3 (en) | Biocidal agent | |
HK1169570A1 (en) | Flavor-improving agent | |
EP2433502A4 (en) | Bitterness-suppressing agent | |
GB0908435D0 (en) | Processes | |
AP2685A (en) | Sulfamoyl-phenyl-ureido benzamidine-derivatives asantimalarial agents | |
GB0900568D0 (en) | Poymerisation | |
GB0900319D0 (en) | Hydrocharger | |
EP2510125A4 (en) | Hyperprimers | |
AU4925P (en) | Bonscawi Scaevola aemula | |
AU4924P (en) | Bonscablue Scaevola aemula | |
AU4240P (en) | Tuckerbox xTriticosecale | |
AU4926P (en) | Bonscalib Scaevola aemula | |
AU2009165V (en) | DB-2W4N Brachychiton Brachychiton garawayae x grandiflorus |