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SE9902765D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE9902765D0
SE9902765D0 SE9902765A SE9902765A SE9902765D0 SE 9902765 D0 SE9902765 D0 SE 9902765D0 SE 9902765 A SE9902765 A SE 9902765A SE 9902765 A SE9902765 A SE 9902765A SE 9902765 D0 SE9902765 D0 SE 9902765D0
Authority
SE
Sweden
Prior art keywords
novel compounds
therapy
processes
preparation
treatment
Prior art date
Application number
SE9902765A
Other languages
English (en)
Swedish (sv)
Inventor
Andrew Baxter
Stephen Brough
Thomas Mcinally
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Priority to SE9902765A priority Critical patent/SE9902765D0/xx
Publication of SE9902765D0 publication Critical patent/SE9902765D0/xx
Priority to CA002378084A priority patent/CA2378084A1/en
Priority to MXPA02000671A priority patent/MXPA02000671A/es
Priority to PCT/GB2000/002756 priority patent/WO2001005782A1/en
Priority to CNB008106703A priority patent/CN1152873C/zh
Priority to DE60001586T priority patent/DE60001586T2/de
Priority to AT00946134T priority patent/ATE233754T1/de
Priority to EP00946134A priority patent/EP1202984B1/en
Priority to JP2001511441A priority patent/JP2003505383A/ja
Priority to US09/623,744 priority patent/US6566376B1/en
Priority to NZ516606A priority patent/NZ516606A/en
Priority to KR1020027000797A priority patent/KR20020027498A/ko
Priority to AU60016/00A priority patent/AU771344B2/en
Priority to BR0012610-1A priority patent/BR0012610A/pt
Priority to IL14714900A priority patent/IL147149A0/xx
Priority to ZA200110540A priority patent/ZA200110540B/xx
Priority to NO20020282A priority patent/NO20020282L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE9902765A 1999-07-21 1999-07-21 Novel compounds SE9902765D0 (sv)

Priority Applications (17)

Application Number Priority Date Filing Date Title
SE9902765A SE9902765D0 (sv) 1999-07-21 1999-07-21 Novel compounds
IL14714900A IL147149A0 (en) 1999-07-21 2000-07-18 Novel diphenyl-piperidine derivate
AT00946134T ATE233754T1 (de) 1999-07-21 2000-07-18 Diphenyl-piperidin derivate
JP2001511441A JP2003505383A (ja) 1999-07-21 2000-07-18 新規ジフェニル−ピペリジン誘導体
PCT/GB2000/002756 WO2001005782A1 (en) 1999-07-21 2000-07-18 Novel diphenyl-piperidine derivate
CNB008106703A CN1152873C (zh) 1999-07-21 2000-07-18 新的二苯基哌啶衍生物
DE60001586T DE60001586T2 (de) 1999-07-21 2000-07-18 Diphenyl-piperidin derivate
CA002378084A CA2378084A1 (en) 1999-07-21 2000-07-18 Novel diphenyl-piperidine derivate
EP00946134A EP1202984B1 (en) 1999-07-21 2000-07-18 diphenyl-piperidine derivate
MXPA02000671A MXPA02000671A (es) 1999-07-21 2000-07-18 Novedoso derivado de difenil-piperidina.
US09/623,744 US6566376B1 (en) 1999-07-21 2000-07-18 Diphenyl-piperidine derivative
NZ516606A NZ516606A (en) 1999-07-21 2000-07-18 Novel diphenyl-piperidine derivate
KR1020027000797A KR20020027498A (ko) 1999-07-21 2000-07-18 신규 디페닐-피페리딘 유도체
AU60016/00A AU771344B2 (en) 1999-07-21 2000-07-18 Novel diphenyl-piperidine derivate
BR0012610-1A BR0012610A (pt) 1999-07-21 2000-07-18 Novo derivado de difenilpiperidina
ZA200110540A ZA200110540B (en) 1999-07-21 2001-12-21 Novel diphenyl-piperidine derivate.
NO20020282A NO20020282L (no) 1999-07-21 2002-01-18 Nytt difenyl-piperidinderivat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9902765A SE9902765D0 (sv) 1999-07-21 1999-07-21 Novel compounds

Publications (1)

Publication Number Publication Date
SE9902765D0 true SE9902765D0 (sv) 1999-07-21

Family

ID=20416552

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9902765A SE9902765D0 (sv) 1999-07-21 1999-07-21 Novel compounds

Country Status (17)

Country Link
US (1) US6566376B1 (zh)
EP (1) EP1202984B1 (zh)
JP (1) JP2003505383A (zh)
KR (1) KR20020027498A (zh)
CN (1) CN1152873C (zh)
AT (1) ATE233754T1 (zh)
AU (1) AU771344B2 (zh)
BR (1) BR0012610A (zh)
CA (1) CA2378084A1 (zh)
DE (1) DE60001586T2 (zh)
IL (1) IL147149A0 (zh)
MX (1) MXPA02000671A (zh)
NO (1) NO20020282L (zh)
NZ (1) NZ516606A (zh)
SE (1) SE9902765D0 (zh)
WO (1) WO2001005782A1 (zh)
ZA (1) ZA200110540B (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200303304A (en) * 2002-02-18 2003-09-01 Astrazeneca Ab Chemical compounds
SE0400208D0 (sv) 2004-02-02 2004-02-02 Astrazeneca Ab Chemical compounds
WO2007070433A2 (en) * 2005-12-12 2007-06-21 Merck & Co., Inc. 2-arylthiazole derivatives as cxcr3 receptor modulators
US10344095B2 (en) * 2006-02-16 2019-07-09 University Of Kentucky Research Foundation CCR3 inhibition for ocular angiogenesis and macular degeneration
TW200812582A (en) * 2006-04-06 2008-03-16 Astrazeneca Ab Medicaments
ATE540942T1 (de) * 2007-07-02 2012-01-15 Hoffmann La Roche Imidazolderivate als ccr2-rezeptor-antagonisten
WO2010129351A1 (en) 2009-04-28 2010-11-11 Schepens Eye Research Institute Method to identify and treat age-related macular degeneration
WO2010138591A1 (en) 2009-05-26 2010-12-02 University Of Kentucky Research Foundation Ccr3 and its ligands are therapeutic and diagnostic targets for neovascular age-related macular degeneration
WO2014153172A1 (en) 2013-03-14 2014-09-25 Epizyme, Inc. Pyrazole derivatives as prmt1 inhibitors and uses thereof
KR102158756B1 (ko) 2013-03-14 2020-09-23 에피자임, 인코포레이티드 아르기닌 메틸기 전이효소 억제제 및 이의 용도
US9045455B2 (en) 2013-03-14 2015-06-02 Epizyme, Inc. Arginine methyltransferase inhibitors and uses thereof
EP3363434A1 (en) 2013-03-14 2018-08-22 Epizyme Inc Arginine methyltransferase inhibitors and uses thereof
US9776972B2 (en) 2013-03-14 2017-10-03 Epizyme Inc. Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof
US20160039767A1 (en) 2013-03-14 2016-02-11 Epizyme, Inc. Pyrazole derivatives as prmt1 inhibitors and uses thereof
WO2014153214A1 (en) 2013-03-14 2014-09-25 Epizyme, Inc. Arginine methyl transferase inhibtors and uses thereof
US9394258B2 (en) 2013-03-14 2016-07-19 Epizyme, Inc. Arginine methyltransferase inhibitors and uses thereof
US9120757B2 (en) 2013-03-14 2015-09-01 Epizyme, Inc. Arginine methyltransferase inhibitors and uses thereof
US9023883B2 (en) 2013-03-14 2015-05-05 Epizyme, Inc. PRMT1 inhibitors and uses thereof
WO2015008230A1 (en) 2013-07-18 2015-01-22 Novartis Ag Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core
CN108299411B (zh) * 2017-01-13 2021-02-05 中国人民解放军军事医学科学院毒物药物研究所 4,4-二苯基哌啶类化合物或其可药用盐、药物组合物及用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2139084C3 (de) 1971-08-04 1979-03-01 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Verfahren zur Herstellung von 4,4-Diphenyl-piperidinen
IL90858A (en) 1988-07-07 1994-08-26 Rhone Poulenc Sante History (Aza) Naftalensultam, their preparation and preparations containing them
EP0524974A1 (de) 1990-04-10 1993-02-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyridine als arzneimittel
DE4140542A1 (de) 1991-12-09 1993-06-17 Bayer Ag Piperdylmethyl substituierte chormanderivate
US6339087B1 (en) 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
DE19756235A1 (de) 1997-12-17 1999-07-01 Klinge Co Chem Pharm Fab Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide
HN1999000149A (es) * 1998-09-09 2000-01-12 Pfizer Prod Inc Derivados de 4,4-biarilpiperidina
US6046331A (en) 1998-12-17 2000-04-04 Synaptic Pharmaceutical Corporation Imidazolones and their use in treating benign prostatic hyperplasia and other disorders

Also Published As

Publication number Publication date
US6566376B1 (en) 2003-05-20
WO2001005782A1 (en) 2001-01-25
NZ516606A (en) 2003-09-26
AU771344B2 (en) 2004-03-18
NO20020282D0 (no) 2002-01-18
EP1202984A1 (en) 2002-05-08
MXPA02000671A (es) 2002-07-02
DE60001586D1 (de) 2003-04-10
IL147149A0 (en) 2002-08-14
CA2378084A1 (en) 2001-01-25
ATE233754T1 (de) 2003-03-15
CN1152873C (zh) 2004-06-09
EP1202984B1 (en) 2003-03-05
NO20020282L (no) 2002-03-21
KR20020027498A (ko) 2002-04-13
ZA200110540B (en) 2003-03-24
AU6001600A (en) 2001-02-05
BR0012610A (pt) 2002-04-09
JP2003505383A (ja) 2003-02-12
CN1361775A (zh) 2002-07-31
DE60001586T2 (de) 2004-02-12

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