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SE9902742D0 - New pharmaceutical formultion - Google Patents

New pharmaceutical formultion

Info

Publication number
SE9902742D0
SE9902742D0 SE9902742A SE9902742A SE9902742D0 SE 9902742 D0 SE9902742 D0 SE 9902742D0 SE 9902742 A SE9902742 A SE 9902742A SE 9902742 A SE9902742 A SE 9902742A SE 9902742 D0 SE9902742 D0 SE 9902742D0
Authority
SE
Sweden
Prior art keywords
formultion
new pharmaceutical
preparation
felodipine
solubilizer
Prior art date
Application number
SE9902742A
Other languages
Swedish (sv)
Inventor
Marianne Eklund
Jan-Erik Loefroth
Mats Sundgren
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9902742A priority Critical patent/SE9902742D0/en
Publication of SE9902742D0 publication Critical patent/SE9902742D0/en
Priority to CA002328102A priority patent/CA2328102A1/en
Priority to EP99964928A priority patent/EP1113786A1/en
Priority to CN99811100A priority patent/CN1319004A/en
Priority to KR1020007011312A priority patent/KR20010078703A/en
Priority to AU30956/00A priority patent/AU3095600A/en
Priority to JP2001510433A priority patent/JP2003504392A/en
Priority to PCT/SE1999/002474 priority patent/WO2001005376A1/en
Priority to NO20004816A priority patent/NO20004816L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

An extended relase preparation of felodipine containing the active compound dissolved or dispersed in a solubilizer as well as a process for the preparation thereof.
SE9902742A 1999-07-20 1999-07-20 New pharmaceutical formultion SE9902742D0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
SE9902742A SE9902742D0 (en) 1999-07-20 1999-07-20 New pharmaceutical formultion
CA002328102A CA2328102A1 (en) 1999-07-20 1999-12-22 New pharmaceutical formulation
EP99964928A EP1113786A1 (en) 1999-07-20 1999-12-22 New pharmaceutical formulation
CN99811100A CN1319004A (en) 1999-07-20 1999-12-22 New pharmaceutical formulation
KR1020007011312A KR20010078703A (en) 1999-07-20 1999-12-22 New Pharmaceutical Formulation
AU30956/00A AU3095600A (en) 1999-07-20 1999-12-22 New pharmaceutical formulation
JP2001510433A JP2003504392A (en) 1999-07-20 1999-12-22 New pharmaceutical formulations
PCT/SE1999/002474 WO2001005376A1 (en) 1999-07-20 1999-12-22 New pharmaceutical formulation
NO20004816A NO20004816L (en) 1999-07-20 2000-09-26 New pharmaceutical formulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9902742A SE9902742D0 (en) 1999-07-20 1999-07-20 New pharmaceutical formultion

Publications (1)

Publication Number Publication Date
SE9902742D0 true SE9902742D0 (en) 1999-07-20

Family

ID=20416534

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9902742A SE9902742D0 (en) 1999-07-20 1999-07-20 New pharmaceutical formultion

Country Status (9)

Country Link
EP (1) EP1113786A1 (en)
JP (1) JP2003504392A (en)
KR (1) KR20010078703A (en)
CN (1) CN1319004A (en)
AU (1) AU3095600A (en)
CA (1) CA2328102A1 (en)
NO (1) NO20004816L (en)
SE (1) SE9902742D0 (en)
WO (1) WO2001005376A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030211149A1 (en) * 2002-05-07 2003-11-13 Sherman Bernard Charles Extended release tablets comprising felodipine
GB0222612D0 (en) * 2002-09-30 2002-11-06 Univ Gent Controlled delivery system for bioactive substances
AR052139A1 (en) * 2004-11-17 2007-03-07 Ares Trading Sa FORMULATIONS OF BENZOTIAZOL AND THE USE OF THE SAME
CN101103964B (en) * 2006-07-14 2010-09-29 海南盛科生命科学研究院 Sustained-release preparation containing felodipine and preparation method thereof
KR100841877B1 (en) * 2006-08-31 2008-06-27 조선대학교산학협력단 Controlled-release formulations of topically solubilized poorly soluble drugs and methods for preparing the same
CN102784128B (en) * 2012-07-31 2015-01-07 北京协和药厂 Felodipine sustained release preparation and preparation method of felodipine sustained release preparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8601624D0 (en) * 1986-04-11 1986-04-11 Haessle Ab NEW PHARMACEUTICAL PREPARATIONS
DE3738236A1 (en) * 1987-11-11 1989-05-24 Euro Celtique Sa BIT CAPSULE
US5773025A (en) * 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
EP0996429B1 (en) * 1997-10-27 2003-02-05 MERCK PATENT GmbH Solid state solutions and dispersions of poorly water soluble drugs

Also Published As

Publication number Publication date
CN1319004A (en) 2001-10-24
JP2003504392A (en) 2003-02-04
NO20004816L (en) 2000-11-02
EP1113786A1 (en) 2001-07-11
NO20004816D0 (en) 2000-09-26
CA2328102A1 (en) 2001-01-20
AU3095600A (en) 2001-02-05
WO2001005376A1 (en) 2001-01-25
KR20010078703A (en) 2001-08-21

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