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SE8504708L - NEW NUCLEOSIDE DERIVATIVES WITH ANTIHERPATIVE PROPERTIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND PROCEDURE FOR THE PREPARATION OF THE ACTIVE INGREDIENTS - Google Patents

NEW NUCLEOSIDE DERIVATIVES WITH ANTIHERPATIVE PROPERTIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND PROCEDURE FOR THE PREPARATION OF THE ACTIVE INGREDIENTS

Info

Publication number
SE8504708L
SE8504708L SE8504708A SE8504708A SE8504708L SE 8504708 L SE8504708 L SE 8504708L SE 8504708 A SE8504708 A SE 8504708A SE 8504708 A SE8504708 A SE 8504708A SE 8504708 L SE8504708 L SE 8504708L
Authority
SE
Sweden
Prior art keywords
preparation
pharmaceutical compositions
same
optionally substituted
antiherpative
Prior art date
Application number
SE8504708A
Other languages
Swedish (sv)
Other versions
SE8504708D0 (en
Inventor
A Szabolcs
L Otvos
A Szemso
H Tudos
J Sagi
Original Assignee
Mta Koezponti Kemiai Kutato In
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mta Koezponti Kemiai Kutato In filed Critical Mta Koezponti Kemiai Kutato In
Publication of SE8504708D0 publication Critical patent/SE8504708D0/en
Publication of SE8504708L publication Critical patent/SE8504708L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

This invention relates to novel nucleoside derivatives of the formula (I> <IMAGE> and the pharmaceutically acceptable acid-addition salts thereof, wherein R and R<1> are the same or different and stand for hydrogen or an optionally substituted acyl, optionally substituted cycloalkanoyl, optionally substituted aroyl or optionally substituted hetereoaroyl. Furthermore the invention relates to antiviral pharmaceutical compositions comprising these compounds, their use as antiviral agents and methods for the preparation of the compounds of the formula (I) and their pharmaceutically acceptable acid-addition salts. R and/or R<1> may also be a blocking group, e.g. (4-methyoxytriphenylmethyl)methyl.
SE8504708A 1984-10-12 1985-10-11 NEW NUCLEOSIDE DERIVATIVES WITH ANTIHERPATIVE PROPERTIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND PROCEDURE FOR THE PREPARATION OF THE ACTIVE INGREDIENTS SE8504708L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU843821A HU192472B (en) 1984-10-12 1984-10-12 Process for preparing /e/-5-/2-bromo-vinyl/-uracyl derivatives

Publications (2)

Publication Number Publication Date
SE8504708D0 SE8504708D0 (en) 1985-10-11
SE8504708L true SE8504708L (en) 1986-04-13

Family

ID=10965655

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8504708A SE8504708L (en) 1984-10-12 1985-10-11 NEW NUCLEOSIDE DERIVATIVES WITH ANTIHERPATIVE PROPERTIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND PROCEDURE FOR THE PREPARATION OF THE ACTIVE INGREDIENTS

Country Status (18)

Country Link
JP (1) JPS61126097A (en)
KR (1) KR870001935B1 (en)
AT (1) ATA294685A (en)
BE (1) BE903381A (en)
DD (1) DD239595A5 (en)
DE (1) DE3536604A1 (en)
DK (1) DK465585A (en)
ES (1) ES8605819A1 (en)
FI (1) FI853969L (en)
FR (1) FR2571726A1 (en)
GB (1) GB2165539A (en)
HU (1) HU192472B (en)
IL (1) IL76661A0 (en)
IT (1) IT1186775B (en)
NL (1) NL8502794A (en)
NO (1) NO854041L (en)
PL (1) PL255741A1 (en)
SE (1) SE8504708L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8912972D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Therapeutic nucleosides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5136498A (en) * 1974-09-20 1976-03-27 Tanabe Seiyaku Co 2 * 2 ** ANHIDOROARABINOFURANOSHIRURASHIRUJUDOTAINOSEIHO
JPS5687599A (en) * 1979-12-19 1981-07-16 Yamasa Shoyu Co Ltd E 55 22halogenovinyl arabinofuranosyluracil and its preparation
NZ199764A (en) * 1981-03-20 1984-08-24 Beecham Group Plc 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
IT8522442A0 (en) 1985-10-11
HUT38655A (en) 1986-06-30
DK465585D0 (en) 1985-10-11
BE903381A (en) 1986-04-07
IL76661A0 (en) 1986-02-28
ES8605819A1 (en) 1986-04-01
PL255741A1 (en) 1986-08-12
KR870001935B1 (en) 1987-10-22
DD239595A5 (en) 1986-10-01
DE3536604A1 (en) 1986-04-17
NL8502794A (en) 1986-05-01
IT1186775B (en) 1987-12-16
SE8504708D0 (en) 1985-10-11
HU192472B (en) 1987-06-29
NO854041L (en) 1986-04-14
GB2165539A (en) 1986-04-16
ATA294685A (en) 1987-03-15
ES547820A0 (en) 1986-04-01
GB8525152D0 (en) 1985-11-13
DK465585A (en) 1986-04-13
FR2571726A1 (en) 1986-04-18
JPS61126097A (en) 1986-06-13
KR860003270A (en) 1986-05-21
FI853969A0 (en) 1985-10-11
FI853969L (en) 1986-04-13

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Effective date: 19870612