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SE8201098L - NEW ERGOLINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF - Google Patents

NEW ERGOLINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF

Info

Publication number
SE8201098L
SE8201098L SE8201098A SE8201098A SE8201098L SE 8201098 L SE8201098 L SE 8201098L SE 8201098 A SE8201098 A SE 8201098A SE 8201098 A SE8201098 A SE 8201098A SE 8201098 L SE8201098 L SE 8201098L
Authority
SE
Sweden
Prior art keywords
preparation
alkyl
pharmaceutical compositions
ergoline derivatives
new ergoline
Prior art date
Application number
SE8201098A
Other languages
Swedish (sv)
Inventor
P Gull
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH121081A external-priority patent/CH645894A5/en
Priority claimed from CH121181A external-priority patent/CH645895A5/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8201098L publication Critical patent/SE8201098L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The compounds have the formula I (FORMULA) wherein R<u1>u is H, a C<u1-4>u alkyl or their precursors, R<u2>u is a C<u1-4>u alkyl, R<u3>u and R<u4>u independently of each other are H, a C alkyl or together are a C alkylene, R<u5>u is H or alkyl and A and B are each H or together represent a bond, providing that, when R<u1>u and R<u2>u = CH<u3>u, R<u3>u and R<u4>u = C<u2>uH<u5>u, A and B = H, R<u5>u is alkyl. Are also concerned the acid addition salts of those compounds. The compounds are used for the treatment of hypertonus, and cardiac insufficiencies.
SE8201098A 1981-02-24 1982-02-22 NEW ERGOLINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF SE8201098L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH121081A CH645894A5 (en) 1981-02-24 1981-02-24 Ergoline derivatives, their preparation and use
CH121181A CH645895A5 (en) 1981-02-24 1981-02-24 Ergoline derivatives, their preparation and use

Publications (1)

Publication Number Publication Date
SE8201098L true SE8201098L (en) 1982-08-25

Family

ID=25687002

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8201098A SE8201098L (en) 1981-02-24 1982-02-22 NEW ERGOLINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF

Country Status (16)

Country Link
AU (1) AU8068282A (en)
CA (1) CA1178582A (en)
DE (1) DE3205169A1 (en)
DK (1) DK77082A (en)
ES (1) ES8304578A1 (en)
FI (1) FI820526L (en)
FR (1) FR2500454A1 (en)
GB (1) GB2093452B (en)
HU (1) HU187650B (en)
IL (1) IL65074A0 (en)
NL (1) NL8200694A (en)
NZ (1) NZ199795A (en)
PH (1) PH17494A (en)
PT (1) PT74468B (en)
SE (1) SE8201098L (en)
WO (1) WO1982002892A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (en) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen NEW ERGOLIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE AS A MEDICINAL PRODUCT
DE3402392A1 (en) * 1984-01-25 1985-08-01 Sandoz-Patent-GmbH, 7850 Lörrach NEW ERGOL DERIVATIVES, THEIR PRODUCTION AND THEIR USE
DE3445784A1 (en) * 1984-12-13 1986-06-26 Schering AG, Berlin und Bergkamen, 1000 Berlin METHOD FOR PRODUCING ERGOLIN DERIVATIVES
DE3528584A1 (en) * 1985-08-06 1987-02-19 Schering Ag NEW 1-ALKYL-ERGOLIN-THIOURINE DERIVATIVES
DE3528576A1 (en) * 1985-08-06 1987-02-19 Schering Ag METHOD FOR THE PRODUCTION OF ERGOLIN THIOUROS
DE3533672A1 (en) * 1985-09-19 1987-03-26 Schering Ag NEW 12- AND 13-SUBSTITUTED ERGOL DERIVATIVES

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1910930A1 (en) * 1968-03-07 1969-10-16 Farmaceutici Italia Process for the production of new 1,6-dimethyl-10alpha-ergoline derivatives
DK140596B (en) * 1971-05-19 1979-10-08 Sandoz Ag Analogous process for the preparation of 8beta- (ureidomethyl) -ergolene derivatives.
CH628049A5 (en) * 1977-03-25 1982-02-15 Sandoz Ag Process for the preparation of ergolene derivatives
FR2421176A1 (en) * 1978-03-29 1979-10-26 Sandoz Sa 2,3-Di:hydro-ergolenyl-methyl urea derivs. - useful as antihypertensives

Also Published As

Publication number Publication date
CA1178582A (en) 1984-11-27
PT74468A (en) 1982-03-01
WO1982002892A1 (en) 1982-09-02
FI820526L (en) 1982-08-25
IL65074A0 (en) 1982-04-30
HU187650B (en) 1986-02-28
DE3205169A1 (en) 1982-10-14
ES509825A0 (en) 1983-03-01
FR2500454A1 (en) 1982-08-27
PH17494A (en) 1984-09-04
GB2093452B (en) 1984-11-07
ES8304578A1 (en) 1983-03-01
PT74468B (en) 1984-08-01
NZ199795A (en) 1985-08-30
DK77082A (en) 1982-08-25
AU8068282A (en) 1982-09-02
GB2093452A (en) 1982-09-02
NL8200694A (en) 1982-09-16
FR2500454B1 (en) 1984-11-09

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