SE7900458L - Liposom-avgivningssystem for lekemedel - Google Patents

Liposom-avgivningssystem for lekemedel

Info

Publication number: SE7900458L
Authority: SE; Sweden
Prior art keywords: medicament; beta; liposom; drug; delivery system
Prior art date: 1978-01-27

Application number

SE7900458A

Other languages

Unknown language ( )

English (en)

Inventor

L A Kelly

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-01-27

Filing date

1979-01-18

Publication date

1979-07-28

1979-01-18 Application filed by Sandoz Ag filed Critical Sandoz Ag

1979-07-28 Publication of SE7900458L publication Critical patent/SE7900458L/sv

Links

239000003814 drug Substances 0.000 title abstract 4
229940079593 drug Drugs 0.000 title 1
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
239000002502 liposome Substances 0.000 abstract 2
QYIXCDOBOSTCEI-QCYZZNICSA-N (5alpha)-cholestan-3beta-ol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 QYIXCDOBOSTCEI-QCYZZNICSA-N 0.000 abstract 1
VOXZDWNPVJITMN-ZBRFXRBCSA-N 17beta-estradiol Natural products OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
YIKKMWSQVKJCOP-ABXCMAEBSA-N 7-ketocholesterol Chemical compound C1C[C@H](O)CC2=CC(=O)[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]3[C@]21C YIKKMWSQVKJCOP-ABXCMAEBSA-N 0.000 abstract 1
BDCFUHIWJODVNG-UHFFFAOYSA-N Desmosterol Natural products C1C=C2CC(O)C=CC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 BDCFUHIWJODVNG-UHFFFAOYSA-N 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
ZPXSCAKFGYXMGA-UHFFFAOYSA-N Mazindol Chemical compound N12CCN=C2C2=CC=CC=C2C1(O)C1=CC=C(Cl)C=C1 ZPXSCAKFGYXMGA-UHFFFAOYSA-N 0.000 abstract 1
229930182558 Sterol Natural products 0.000 abstract 1
-1 aliphatic lipid Chemical class 0.000 abstract 1
QYIXCDOBOSTCEI-UHFFFAOYSA-N alpha-cholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 QYIXCDOBOSTCEI-UHFFFAOYSA-N 0.000 abstract 1
229940076810 beta sitosterol Drugs 0.000 abstract 1
LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 abstract 1
NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
AVSXSVCZWQODGV-DPAQBDIFSA-N desmosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@@H](CCC=C(C)C)C)[C@@]1(C)CC2 AVSXSVCZWQODGV-DPAQBDIFSA-N 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
229960003133 ergot alkaloid Drugs 0.000 abstract 1
229960005309 estradiol Drugs 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
239000004973 liquid crystal related substance Substances 0.000 abstract 1
229960000299 mazindol Drugs 0.000 abstract 1
239000000693 micelle Substances 0.000 abstract 1
VOXZDWNPVJITMN-WKUFJEKOSA-N oestradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-WKUFJEKOSA-N 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
239000008024 pharmaceutical diluent Substances 0.000 abstract 1
159000000001 potassium salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 abstract 1
229950005143 sitosterol Drugs 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 abstract 1
150000003432 sterols Chemical class 0.000 abstract 1
235000003702 sterols Nutrition 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SE7900458A 1978-01-27 1979-01-18 Liposom-avgivningssystem for lekemedel SE7900458L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US87283578A	1978-01-27	1978-01-27

Publications (1)

Publication Number	Publication Date
SE7900458L true SE7900458L (sv)	1979-07-28

Family

ID=25360392

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7900458A SE7900458L (sv)	1978-01-27	1979-01-18	Liposom-avgivningssystem for lekemedel

Country Status (19)

Country	Link
JP (1)	JPS54113417A (sv)
AT (1)	AT368888B (sv)
AU (1)	AU524529B2 (sv)
BE (1)	BE873715A (sv)
CA (1)	CA1111347A (sv)
DE (1)	DE2902672A1 (sv)
DK (1)	DK22879A (sv)
ES (1)	ES477217A1 (sv)
FI (1)	FI790164A (sv)
FR (1)	FR2415460A1 (sv)
GB (1)	GB2013087B (sv)
IE (1)	IE790144L (sv)
IL (1)	IL56499A (sv)
IT (1)	IT1109867B (sv)
NL (1)	NL7900545A (sv)
NZ (1)	NZ189477A (sv)
PT (1)	PT69132A (sv)
SE (1)	SE7900458L (sv)
ZA (1)	ZA79349B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2026340B (en) *	1978-07-03	1982-12-22	Ash P	Stabilising microvesicles
JPS5874619A (ja) *	1981-10-29	1983-05-06	Nippon Shinyaku Co Ltd	リポソ−ム及びその製法
EP0088046B1 (de) *	1982-02-17	1987-12-09	Ciba-Geigy Ag	Lipide in wässriger Phase
EP0102324A3 (de) *	1982-07-29	1984-11-07	Ciba-Geigy Ag	Lipide und Tenside in wässriger Phase
DE3421468A1 (de) *	1984-06-08	1985-12-19	Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim	Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
US4849227A (en) *	1986-03-21	1989-07-18	Eurasiam Laboratories, Inc.	Pharmaceutical compositions
US5077211A (en) *	1988-07-06	1991-12-31	Applied Genetics, Inc.	Purification and administration of dna repair enzymes
WO1992003123A1 (en) *	1990-08-28	1992-03-05	Liposome Technology, Inc.	Liposome alternative bilayer formulations
FR2714621B1 (fr) *	1994-01-06	1996-02-23	Centre Nat Rech Scient	Procédé de préparation de liposomes sans utilisation de solvant organique.
WO2001012780A1 (fr)	1999-08-13	2001-02-22	Suntory Limited	Micro-organisme secretant un lipide et procede de production de ce lipide et de capsules contenant ce lipide au moyen de ce micro-organisme
JP4088097B2 (ja)	2002-04-26	2008-05-21	サントリー株式会社	高度不飽和脂肪酸含有脂質の製造方法
FR2979239A1 (fr) *	2011-08-25	2013-03-01	Trophos	Liposome comprenant au moins un derive de cholesterol
AU2013203682B2 (en) *	2011-08-25	2016-03-31	Trophos	Liposome comprising at least one cholesterol derivative
CN113967192A (zh) *	2021-11-09	2022-01-25	陕西海斯夫生物工程有限公司	一种用于加速伤口愈合的药物组合物、它们的制备方法与用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3957951A (en) *	1974-08-23	1976-05-18	International Telephone And Telegraph Corporation	Process for removing contaminants from hot waste gas streams
FR2315991A1 (fr) *	1975-06-30	1977-01-28	Oreal	Procede de fabrication de dispersions aqueuses de spherules lipidiques et nouvelles compositions correspondantes
FR2408387A2 (fr) *	1975-06-30	1979-06-08	Oreal	Compositions a base de dispersions aqueuses de spherules lipidiques
FR2374910A1 (fr) *	1976-10-23	1978-07-21	Choay Sa	Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations

1979
- 1979-01-18 SE SE7900458A patent/SE7900458L/sv not_active Application Discontinuation
- 1979-01-18 FI FI790164A patent/FI790164A/fi unknown
- 1979-01-18 DK DK22879A patent/DK22879A/da not_active Application Discontinuation
- 1979-01-24 DE DE19792902672 patent/DE2902672A1/de not_active Withdrawn
- 1979-01-24 NL NL7900545A patent/NL7900545A/xx not_active Application Discontinuation
- 1979-01-25 AU AU43678/79A patent/AU524529B2/en not_active Ceased
- 1979-01-25 CA CA320,271A patent/CA1111347A/en not_active Expired
- 1979-01-25 BE BE0/193081A patent/BE873715A/xx not_active IP Right Cessation
- 1979-01-25 IL IL56499A patent/IL56499A/xx unknown
- 1979-01-25 NZ NZ189477A patent/NZ189477A/xx unknown
- 1979-01-26 PT PT7969132A patent/PT69132A/pt unknown
- 1979-01-26 ZA ZA79349A patent/ZA79349B/xx unknown
- 1979-01-26 FR FR7901999A patent/FR2415460A1/fr active Granted
- 1979-01-26 AT AT0058979A patent/AT368888B/de not_active IP Right Cessation
- 1979-01-26 JP JP730779A patent/JPS54113417A/ja active Pending
- 1979-01-26 ES ES477217A patent/ES477217A1/es not_active Expired
- 1979-01-26 GB GB7902881A patent/GB2013087B/en not_active Expired
- 1979-01-26 IT IT19649/79A patent/IT1109867B/it active
- 1979-01-30 IE IE790144A patent/IE790144L/xx unknown

Also Published As

Publication number	Publication date
IE790144L (en)	1979-07-27
NL7900545A (nl)	1979-07-31
CA1111347A (en)	1981-10-27
AU4367879A (en)	1979-08-02
NZ189477A (en)	1981-05-01
PT69132A (fr)	1979-02-01
FI790164A (fi)	1979-07-28
FR2415460A1 (fr)	1979-08-24
DE2902672A1 (de)	1979-08-02
ZA79349B (en)	1980-09-24
ATA58979A (de)	1982-04-15
GB2013087B (en)	1982-07-21
IL56499A0 (en)	1979-03-12
ES477217A1 (es)	1980-04-01
AU524529B2 (en)	1982-09-23
IT7919649A0 (it)	1979-01-26
AT368888B (de)	1982-11-25
BE873715A (fr)	1979-07-25
IL56499A (en)	1981-09-13
GB2013087A (en)	1979-08-08
DK22879A (da)	1979-07-28
FR2415460B1 (sv)	1983-05-20
JPS54113417A (en)	1979-09-05
IT1109867B (it)	1985-12-23

Publication	Publication Date	Title
SE7900458L (sv)	1979-07-28	Liposom-avgivningssystem for lekemedel
ZA88562B (en)	1988-08-03	Mixed micelle solutions
NO863620L (no)	1987-03-12	Fremgangsmaate for fremstilling av et farmasoeytisk preparat
ES8104720A1 (es)	1981-05-16	Un procedimiento para la preparacion de composiciones lipo- somicas de substancias activas grasosolubles
NL930003I2 (nl)	1994-03-01	Werkwijze voor het bereiden van een geneesmiddel; een aldus gevormd geneesmiddel; en een werkwijze voor het bereiden van geneeskrachtige verbindingen.
GB1601613A (en)	1981-11-04	Compositions for rectal use
IT8767796A0 (it)	1987-09-17	Forma farmaceutica di dosaggio per somministrazione orale con erogazione controllata di un ingrediente attivo
DK137310B (da)	1978-02-20	Fremgangsmade til fremstilling af fedtsyretriglyceridindkapslede legemidler med forsinkel afgivelse af virksomt stof i tarmen
NO177177C (no)	1995-08-02	Fremgangsmåte for fremstilling av en flytende doseringsform for oral administrasjon av en farmasöytisk substans
JPS5225013A (en)	1977-02-24	Insulin pharmaceutical for nasal administration
NO175620C (no)	1994-11-09	Fremgangsmåte for fremstilling av et antitumorvirksomt legemiddel
NO842290L (no)	1984-12-10	Fremgangsmaate for fremstilling av preparater inneholdende oralt antidiabetisk aktive stoffer
NZ225242A (en)	1991-10-25	Pad printing process for manufacturing a pharmaceutical presentation and/or dosage form for active ingredients of drugs
DK62187A (da)	1987-08-14	Farmaceutisk praeparat indeholdende 3alfa-hydroxy-5beta-pregnan-20-on og fremstilling deraf
CS8804389A2 (en)	1991-03-12	Method of pharmaceutical preparation formulation with laminar structure for transdermal administration of active substance with null kinetic order
EP0271151A3 (en)	1988-07-27	Azumolene dosage form
KR860006265A (ko)	1986-09-09	9,10-디하이드로 에르고트 알카로이드를 함유하는 서방성 제재의 제조방법
JPS56161317A (en)	1981-12-11	Pharmaceutical preparation of fatty corpuscle of steroid
IT1058141B (it)	1982-04-10	Perfezionamento nelle capsule per prodotti farmaceutici solubili in ameiente alcalino
ES2062763T3 (es)	1994-12-16	Preparacion farmaceutica de 1-octadecil-2-metil-glicero-3-fosfocolina administrable por via intravenosa.
JPS57179114A (en)	1982-11-04	Acetylsalicylic acid liposome preparation
HU901875D0 (en)	1990-07-28	Process for production of galenical preparations providing optimal biological accessibility of 2-hydroxi-5-methyl-laurophenon-oxim as active substance
BE839102A (fr)	1976-07-01	0-acetoxybenzoyl-1 hydroxy-4-l-pyroline et 0-acetoxybenzoyl-1-l-proline, leur procede de preparation et leur application en tant que substance active po ur medicament
IE38781B1 (en)	1978-05-24	A medicament pack for the oral treatment with oestrogen
TH5133EX (th)	1988-09-01	สารผสมทางเภสัชกรรม

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