SE440779B - Sett att framstella androstan-17-on-derivat - Google Patents

Sett att framstella androstan-17-on-derivat

Info

Publication number: SE440779B
Authority: SE; Sweden
Prior art keywords: androstan; derivatives; make; make androstan
Prior art date: 1976-07-16

Application number

SE7708192A

Other languages

English (en)

Other versions

SE7708192L (sv

Inventor

A Weber

M Kennecke

H Dahl

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-16

Filing date

1977-07-14

Publication date

1985-08-19

1977-07-14 Application filed by Schering Ag filed Critical Schering Ag

1978-01-17 Publication of SE7708192L publication Critical patent/SE7708192L/sv

1985-08-19 Publication of SE440779B publication Critical patent/SE440779B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Chemical & Material Sciences (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SE7708192A 1976-07-16 1977-07-14 Sett att framstella androstan-17-on-derivat SE440779B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19762632677 DE2632677A1 (de)	1976-07-16	1976-07-16	Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung

Publications (2)

Publication Number	Publication Date
SE7708192L SE7708192L (sv)	1978-01-17
SE440779B true SE440779B (sv)	1985-08-19

Family

ID=5983514

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7708192A SE440779B (sv)	1976-07-16	1977-07-14	Sett att framstella androstan-17-on-derivat

Country Status (18)

Country	Link
US (1)	US4179336A (sv)
JP (1)	JPS5315493A (sv)
AT (1)	AT363196B (sv)
BE (1)	BE856860A (sv)
CH (3)	CH627190A5 (sv)
CS (1)	CS200517B2 (sv)
DD (4)	DD136142A5 (sv)
DE (1)	DE2632677A1 (sv)
DK (1)	DK142372C (sv)
FR (4)	FR2365588A1 (sv)
GB (1)	GB1585786A (sv)
HU (4)	HU179344B (sv)
IE (1)	IE45304B1 (sv)
IT (1)	IT1077339B (sv)
NL (1)	NL7706638A (sv)
SE (1)	SE440779B (sv)
SU (1)	SU980628A3 (sv)
YU (1)	YU164277A (sv)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55148083A (en) *	1979-05-04	1980-11-18	Mitsubishi Chem Ind Ltd	Microorganism
JPS55150893A (en) *	1979-05-11	1980-11-25	Mitsubishi Chem Ind Ltd	Novel microorganism
JPS578794A (en) *	1980-06-17	1982-01-18	Mitsubishi Chem Ind Ltd	Preparation of androstane-type steroid
US4444884A (en) *	1982-05-25	1984-04-24	Wisconsin Alumni Research Foundation	Process for preparing steroids
US4755463A (en) *	1982-05-25	1988-07-05	Wisconsin Alumni Research Foundation	Process for preparing steroids
JPH0512528Y2 (sv) *	1987-09-08	1993-03-31
EP0738703B1 (en) *	1995-02-28	2002-05-22	Nippon Shokubai Co., Ltd.	Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers
NZ541374A (en) *	2003-05-23	2008-09-26	Nektar Therapeutics Al Corp	PEG derivatives having an amidocarbonate linkage
WO2011053048A2 (ko) *	2009-10-29	2011-05-05	연세대학교 산학협력단	신규 혈관누출 차단제
US9388210B2 (en)	2011-02-25	2016-07-12	Washington University	Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
ES2738526T3 (es)	2011-10-14	2020-01-23	Sage Therapeutics Inc	Compuestos 19-norpregnano 3,3-disustituidos, composiciones y usos de los mismos
IL278396B2 (en)	2012-12-18	2024-07-01	Washington University St Louis	Neuroactive steroids converted at the 19th position to the 17th position, their prodrugs, and methods of treatment using them
WO2014127201A1 (en) *	2013-02-15	2014-08-21	Washington University	Neuroactive enantiomeric 15-, 16- and 17-substituted steroids as modulators for gaba type-a receptors
US9512170B2 (en)	2013-03-01	2016-12-06	Washington University	Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en)	2013-03-11	2016-06-14	Washington University	Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en)	2013-03-14	2017-02-07	Washington University	Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
ES2886182T3 (es)	2013-04-17	2021-12-16	Sage Therapeutics Inc	C21-N-pirazolil-esteroide 19-nor C3,3-disustituido para su uso en terapia
HUE051403T2 (hu)	2013-04-17	2021-03-01	Sage Therapeutics Inc	Neuroaktív 19-nor-szteroidok kezelési eljárásokhoz
WO2014169836A1 (en)	2013-04-17	2014-10-23	Sage Therapeutics, Inc.	19-nor neuroactive steroids and methods of use thereof
US9725481B2 (en)	2013-04-17	2017-08-08	Sage Therapeutics, Inc.	19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
AU2014290400B2 (en)	2013-07-19	2019-12-05	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
BR112016003862B1 (pt)	2013-08-23	2022-09-06	Sage Therapeutics, Inc	Compostos esteroides neuroativos, suas composições e seus usos
US10246482B2 (en)	2014-06-18	2019-04-02	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
WO2016061527A1 (en)	2014-10-16	2016-04-21	Sage Therapeutics, Inc.	Compositions and methods for treating cns disorders
ME03809B (me)	2014-10-16	2021-04-20	Sage Therapeutics Inc	KOMPOZICIJE I POSTUPCI ZA LEČENJE POREMEĆAJA CNS-a
RS60343B1 (sr)	2014-11-27	2020-07-31	Sage Therapeutics Inc	Kompozicije i postupci za lečenje poremećaja cns-a
ES2857082T3 (es)	2015-01-26	2021-09-28	Sage Therapeutics Inc	Composiciones y métodos para el tratamiento de trastornos del SNC
EP4155314A1 (en)	2015-02-20	2023-03-29	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
AU2017296295B2 (en)	2016-07-11	2022-02-24	Sage Therapeutics, Inc.	C7, C12, and C16 substituted neuroactive steroids and their methods of use
ES2965214T3 (es)	2016-07-11	2024-04-11	Sage Therapeutics Inc	Esteroides neuroactivos sustituidos en C17, C20 y C21 y sus procedimientos de utilización
CA3139554A1 (en)	2019-05-31	2020-12-03	Sage Therapeutics, Inc.	Neuroactive steroids and compositions thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3451892A (en) *	1965-10-19	1969-06-24	Schering Corp	Process for the preparation of steroidal compounds
NL6705450A (sv) *	1965-10-22	1968-10-21
US3684657A (en) *	1970-05-11	1972-08-15	Searle & Co	Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) *	1970-12-10	1973-09-18	Searle & Co	Selective microbiological preparation of androst-4-ene-3,17-dione
US3738983A (en) *	1971-08-06	1973-06-12	Searle & Co	Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone
DE2534911C2 (de) *	1975-08-01	1985-04-18	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten

1976
- 1976-07-16 DE DE19762632677 patent/DE2632677A1/de active Granted
1977
- 1977-06-16 NL NL7706638A patent/NL7706638A/xx not_active Application Discontinuation
- 1977-07-01 YU YU01642/77A patent/YU164277A/xx unknown
- 1977-07-06 US US05/813,391 patent/US4179336A/en not_active Expired - Lifetime
- 1977-07-12 CH CH861377A patent/CH627190A5/de not_active IP Right Cessation
- 1977-07-13 IE IE1456/77A patent/IE45304B1/en unknown
- 1977-07-13 AT AT0504677A patent/AT363196B/de not_active IP Right Cessation
- 1977-07-13 CS CS774682A patent/CS200517B2/cs unknown
- 1977-07-14 DD DD77206207A patent/DD136142A5/xx unknown
- 1977-07-14 DD DD7700200065A patent/DD132439A5/xx not_active IP Right Cessation
- 1977-07-14 DD DD77206210A patent/DD137235A5/xx unknown
- 1977-07-14 SE SE7708192A patent/SE440779B/sv not_active IP Right Cessation
- 1977-07-14 DD DD77206205A patent/DD136141A5/xx unknown
- 1977-07-15 HU HU77SCHE614A patent/HU179344B/hu not_active IP Right Cessation
- 1977-07-15 GB GB29800/77A patent/GB1585786A/en not_active Expired
- 1977-07-15 BE BE179384A patent/BE856860A/xx not_active IP Right Cessation
- 1977-07-15 HU HU8019A patent/HU182790B/hu unknown
- 1977-07-15 JP JP8493277A patent/JPS5315493A/ja active Granted
- 1977-07-15 SU SU772502698A patent/SU980628A3/ru active
- 1977-07-15 DK DK323677A patent/DK142372C/da not_active IP Right Cessation
- 1977-07-15 HU HU8020A patent/HU182681B/hu unknown
- 1977-07-15 IT IT25807/77A patent/IT1077339B/it active
- 1977-07-15 HU HU8018A patent/HU182789B/hu unknown
- 1977-07-18 FR FR7721932A patent/FR2365588A1/fr active Granted
1978
- 1978-03-07 FR FR7806456A patent/FR2372174A1/fr active Pending
- 1978-03-07 FR FR7806457A patent/FR2372176A1/fr active Pending
- 1978-03-07 FR FR7806455A patent/FR2372175A1/fr active Pending
1981
- 1981-06-23 CH CH415281A patent/CH629222A5/de not_active IP Right Cessation
- 1981-06-23 CH CH415381A patent/CH629503A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE2632677C2 (sv)	1988-06-16
CH627190A5 (sv)	1981-12-31
CH629503A5 (de)	1982-04-30
HU179344B (en)	1982-10-28
DD137235A5 (de)	1979-08-22
JPS6117477B2 (sv)	1986-05-07
US4179336A (en)	1979-12-18
FR2372174A1 (fr)	1978-06-23
IE45304L (en)	1978-01-16
GB1585786A (en)	1981-03-11
JPS5315493A (en)	1978-02-13
YU164277A (en)	1982-08-31
BE856860A (fr)	1978-01-16
HU182790B (en)	1984-03-28
AT363196B (de)	1981-07-10
NL7706638A (nl)	1978-01-18
ATA504677A (de)	1980-12-15
DK323677A (da)	1978-01-17
IT1077339B (it)	1985-05-04
HU182789B (en)	1984-03-28
CH629222A5 (de)	1982-04-15
SE7708192L (sv)	1978-01-17
FR2365588A1 (fr)	1978-04-21
DK142372C (da)	1981-03-23
HU182681B (en)	1984-02-28
IE45304B1 (en)	1982-07-28
SU980628A3 (ru)	1982-12-07
CS200517B2 (en)	1980-09-15
FR2372176A1 (fr)	1978-06-23
DK142372B (da)	1980-10-20
DE2632677A1 (de)	1978-01-26
DD136142A5 (de)	1979-06-20
DD132439A5 (de)	1978-09-27
FR2365588B1 (sv)	1982-06-25
FR2372175A1 (fr)	1978-06-23
DD136141A5 (de)	1979-06-20

Publication	Publication Date	Title
SE440779B (sv)	1985-08-19	Sett att framstella androstan-17-on-derivat
SE431935B (sv)	1984-03-12	Sett att framstella drageer
SE433819B (sv)	1984-06-18	Sett att framstella pleterade stalror
SE433222B (sv)	1984-05-14	Sett att framstella modifierad polysackarid
SE7805276L (sv)	1978-11-11	Sett att framstella liposomblandningar
SE432247B (sv)	1984-03-26	Sett att framstella dihydro-cyklosporin c
SE429551B (sv)	1983-09-12	Sett att framstella 1-(3-dimetylamino-propyl)-ftalanderivat
SE7606280L (sv)	1976-12-07	Sett att framstella etrar
SE441042B (sv)	1985-09-02	Sett att pavisa rheumatoida faktorer
SE435928B (sv)	1984-10-29	Sett att framstella nya 3-aryl-oxazolidin-2-oner
SE432256B (sv)	1984-03-26	Sett att framstella cellulosaalkyletrar
SE420728B (sv)	1981-10-26	Sett att framstella piperazinyliminorifamyciner
SE425736B (sv)	1982-11-01	Sett att framstella kromanon-(4)
SE427111B (sv)	1983-03-07	Sett att framstella pilokarpiniumsalter
SE430687B (sv)	1983-12-05	Sett att framstella hexanitrostilben
SE7708841L (sv)	1978-03-31	Sett att framstella rifamycinforeningar
SE420732B (sv)	1981-10-26	Sett att framstella 4-gonen-3-oner
SE436037B (sv)	1984-11-05	Sett att framstella nya 11-desoxi-prostaglandin-f?712-derivat
SE425321B (sv)	1982-09-20	Sett att reducera vanadinoxider
SE7804126L (sv)	1978-10-15	Sett att framstella vulkanisat
SE434397B (sv)	1984-07-23	Sett att framstella bens-acyl-bensimidazol-2-derivat
SE430156B (sv)	1983-10-24	Sett att framstella 2-subst-1-(omega-aminoalkoxi)-bensener
SE430505B (sv)	1983-11-21	Sett att framstella en substituerad purin
SE7713868L (sv)	1978-06-09	Sett att framstella tegel
SE433213B (sv)	1984-05-14	Sett att framstella 2 -fenyl-3-amino-benso/b/tiofenderivat

Legal Events

Date	Code	Title	Description
1995-01-31	NUG	Patent has lapsed	Ref document number: 7708192-5 Effective date: 19930204 Format of ref document f/p: F

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7708192-5

Effective date: 19930204

Format of ref document f/p: F