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SE419339B - Forfarande for framstellning av substituerade sulfonylacetamidocefalosporiner - Google Patents

Forfarande for framstellning av substituerade sulfonylacetamidocefalosporiner

Info

Publication number
SE419339B
SE419339B SE7306097A SE7306097A SE419339B SE 419339 B SE419339 B SE 419339B SE 7306097 A SE7306097 A SE 7306097A SE 7306097 A SE7306097 A SE 7306097A SE 419339 B SE419339 B SE 419339B
Authority
SE
Sweden
Prior art keywords
sulphonylacetamidocephalosporines
procedure
preparing substituted
substituted
preparing
Prior art date
Application number
SE7306097A
Other languages
English (en)
Inventor
R M Demarinis
J R E Hoover
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of SE419339B publication Critical patent/SE419339B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
SE7306097A 1972-05-03 1973-05-02 Forfarande for framstellning av substituerade sulfonylacetamidocefalosporiner SE419339B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US249858A US3865819A (en) 1972-05-03 1972-05-03 Substituted sulfonylacetamido cephalosporins

Publications (1)

Publication Number Publication Date
SE419339B true SE419339B (sv) 1981-07-27

Family

ID=22945311

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7306097A SE419339B (sv) 1972-05-03 1973-05-02 Forfarande for framstellning av substituerade sulfonylacetamidocefalosporiner

Country Status (12)

Country Link
US (1) US3865819A (sv)
JP (1) JPS4954391A (sv)
AU (1) AU466397B2 (sv)
BE (1) BE798927A (sv)
CA (1) CA1027110A (sv)
CH (1) CH594683A5 (sv)
DE (1) DE2322127A1 (sv)
FR (1) FR2183225B1 (sv)
GB (1) GB1363222A (sv)
NL (1) NL7305941A (sv)
SE (1) SE419339B (sv)
ZA (1) ZA732980B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880848A (en) * 1973-06-18 1975-04-29 Smithkline Corp 7-Trifluorome thylsulfinylacetamido cephalosporins
US3963709A (en) * 1973-08-17 1976-06-15 Smithkline Corporation Cyanomethyl sulfinyl- and sulfonyl-acetamido cephalosporins
US3963711A (en) * 1973-08-17 1976-06-15 Smithkline Corporation Cyanomethyl sulfinyl- and sulfonyl-acetamido cephalosporins
US3998819A (en) * 1973-12-26 1976-12-21 Smithkline Corporation Trifluoroethyl-mercapto, -sulfinyl or -sulfonyl acetamidocephalosporins
US3998818A (en) * 1973-12-26 1976-12-21 Smithkline Corporation Trifluoroethylmercapto, -sulfinyl or -sulfonyl acetamidocephalosporins
US4086340A (en) * 1974-02-18 1978-04-25 Bayer Aktiengesellschaft Cephalosporins and their production
US4107304A (en) * 1974-02-18 1978-08-15 Bayer Aktiengesellschaft Oxo-imidazolidine substituted cephalosporins and antibacterial compositions and methods of combatting bacteria employing them
US4091217A (en) * 1974-05-28 1978-05-23 Toshiyasu Ishimaru 7-((5'-N-Methylthioacetamido)-adipoamido)cephalosporin derivatives
GB1457238A (en) * 1974-05-28 1976-12-01 Sangyo Kagaku Kenkyu Kyokai Cephalosporin derivatives
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
DK586175A (da) * 1974-12-28 1976-06-29 Asahi Chemical Ind Cephalosporin-forbindelser
US4093723A (en) * 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
US4020057A (en) * 1975-06-18 1977-04-26 Smithkline Corporation 7β-Acyloxy cephalosporins
US4075338A (en) * 1975-12-29 1978-02-21 Smithkline Corporation Substituted acetamidocephalosporins
US4041162A (en) * 1976-03-11 1977-08-09 Smithkline Corporation 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4034092A (en) * 1976-05-03 1977-07-05 Smithkline Corporation 7-Acyl-3-(carboxyalkyl and carbamoylalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4229573A (en) * 1977-06-21 1980-10-21 Asahi Kasei Kogyo Kabushiki Kaisha 7α-Methoxycephalosporin derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1067965A (en) * 1965-01-22 1967-05-10 Beecham Group Ltd Penicillins, esters, amides and salts thereof
GB1279402A (en) * 1968-06-14 1972-06-28 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3657232A (en) * 1970-06-19 1972-04-18 R & L Molecular Research Ltd 7-((o-aminomethylphenylthio)-acetamido) cephalosporanic acid

Also Published As

Publication number Publication date
ZA732980B (en) 1974-04-24
FR2183225B1 (sv) 1976-12-31
JPS4954391A (sv) 1974-05-27
NL7305941A (sv) 1973-11-06
BE798927A (fr) 1973-10-30
CA1027110A (en) 1978-02-28
US3865819A (en) 1975-02-11
AU466397B2 (en) 1975-10-30
CH594683A5 (sv) 1978-01-31
DE2322127A1 (de) 1973-11-22
GB1363222A (en) 1974-08-14
AU5515173A (en) 1974-11-07
FR2183225A1 (sv) 1973-12-14

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