SE387122B - Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan - Google Patents
Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkanInfo
- Publication number
- SE387122B SE387122B SE7207142A SE714272A SE387122B SE 387122 B SE387122 B SE 387122B SE 7207142 A SE7207142 A SE 7207142A SE 714272 A SE714272 A SE 714272A SE 387122 B SE387122 B SE 387122B
- Authority
- SE
- Sweden
- Prior art keywords
- tiopyrano
- pyrano
- indole
- procedure
- preparation
- Prior art date
Links
- DULBEIKUQPJAST-UHFFFAOYSA-N pyrano[3,4-b]indole Chemical compound O1C=CC2=C3C=CC=CC3=NC2=C1 DULBEIKUQPJAST-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- H01L29/73—
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00148895A US3843681A (en) | 1971-06-01 | 1971-06-01 | 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
SE387122B true SE387122B (sv) | 1976-08-30 |
Family
ID=22527916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7207142A SE387122B (sv) | 1971-06-01 | 1972-05-31 | Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan |
Country Status (23)
Country | Link |
---|---|
US (1) | US3843681A (sv) |
JP (1) | JPS5638594B1 (sv) |
AR (1) | AR198787A1 (sv) |
AU (1) | AU463079B2 (sv) |
BE (1) | BE784284A (sv) |
CA (1) | CA1006875A (sv) |
CH (1) | CH580101A5 (sv) |
CS (1) | CS178409B2 (sv) |
DE (1) | DE2226340A1 (sv) |
DK (1) | DK155328C (sv) |
ES (1) | ES403343A1 (sv) |
FI (1) | FI54125C (sv) |
FR (1) | FR2140154B1 (sv) |
GB (1) | GB1391005A (sv) |
HK (1) | HK13078A (sv) |
HU (1) | HU169432B (sv) |
IL (1) | IL39466A (sv) |
MY (1) | MY7800237A (sv) |
NL (1) | NL173405C (sv) |
PH (2) | PH10625A (sv) |
SE (1) | SE387122B (sv) |
SU (1) | SU463262A3 (sv) |
ZA (1) | ZA723344B (sv) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3974179A (en) * | 1971-06-01 | 1976-08-10 | American Home Products Corporation | 1,3,4,9-Tetrahydropyrano[3,4-b]indole-1-acetamides and derivatives |
US4118394A (en) * | 1976-10-18 | 1978-10-03 | Ayerst, Mckenna & Harrison Limited | Pyrano- and thiopyranoindole derivatives |
US4179503A (en) * | 1978-05-08 | 1979-12-18 | American Home Products Corp. | 1-Hydroxyalkanamine pyrano[3,4-b]indole derivatives |
US4309348A (en) * | 1979-05-14 | 1982-01-05 | American Home Products Corporation | Tricyclic indole derivatives |
US4235903A (en) * | 1979-08-06 | 1980-11-25 | American Home Products Corporation | 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use |
US4319029A (en) * | 1979-08-06 | 1982-03-09 | American Home Products Corporation | Hydroxyalkanamide tetrahydrocarbazoles |
JPS58179164A (ja) * | 1982-04-10 | 1983-10-20 | Toshiharu Nakai | 金属表面処理等に用いられるscr整流器の定格直流電圧選定方法並びに定格直流電圧切替方法 |
US4971960A (en) * | 1986-03-11 | 1990-11-20 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4826994A (en) * | 1986-03-11 | 1989-05-02 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids |
US4775690A (en) * | 1987-01-13 | 1988-10-04 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4670462A (en) * | 1986-03-11 | 1987-06-02 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids |
US4663345A (en) * | 1986-04-17 | 1987-05-05 | American Home Products Corporation | Etodolac for treatment of gout |
US4748252A (en) * | 1986-08-15 | 1988-05-31 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4686213A (en) * | 1986-08-15 | 1987-08-11 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4810699A (en) * | 1987-02-20 | 1989-03-07 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano[3,4,-b]indole-1-acetic acids, pharmaceutical compositions containing them, and methods for treating inflammatory conditions and for analgesic purposes using them |
US4824961A (en) * | 1987-08-27 | 1989-04-25 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4897493A (en) * | 1987-08-27 | 1990-01-30 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4822781A (en) * | 1987-10-08 | 1989-04-18 | American Home Products | Substituted-8-alkenyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids |
US4822893A (en) * | 1988-02-08 | 1989-04-18 | American Home Products | Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4873257A (en) * | 1988-04-21 | 1989-10-10 | American Home Products Corporation | Susbtituted fused tetrahydrocarbazole acetic acid derivatives |
CA2131992A1 (en) * | 1992-03-13 | 1993-09-16 | James W. Young | Antipyretic and analgesic methods and compositions containing optically pure r-etodolac |
IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
US6103765A (en) | 1997-07-09 | 2000-08-15 | Androsolutions, Inc. | Methods for treating male erectile dysfunction |
KR20010021625A (ko) | 1997-07-09 | 2001-03-15 | 추후보정 | 개선된 남성발기 기능장애 치료방법 및 그 조성물 |
US6573292B1 (en) * | 1998-07-09 | 2003-06-03 | Salmedix, Inc. | Methods and compositions for the treatment of chronic lymphocytic leukemia |
US6066741A (en) * | 1998-09-08 | 2000-05-23 | A.M.S.A. Anonima Materie Sintetiche & Affini S.P.A. | Process for the preparation of etodolac |
IT1308633B1 (it) | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
US6545034B1 (en) * | 1999-07-23 | 2003-04-08 | The Regents Of The University Of California | Use of etodolac for the treatment of chronic lymphocytic leukemia |
US7151100B1 (en) * | 1999-07-23 | 2006-12-19 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7361680B2 (en) * | 1999-07-23 | 2008-04-22 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7129262B2 (en) * | 1999-07-23 | 2006-10-31 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7105560B1 (en) | 1999-07-23 | 2006-09-12 | The Regents Of The University Of California | Use of etodolac in the treatment of multiple myeloma |
IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
IT1318673B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Farmaci per le disfunzioni sessuali. |
US20040152672A1 (en) * | 2000-08-09 | 2004-08-05 | Carson Dennis A. | Indole compounds useful for the treatment of cancer |
CA2419060A1 (en) * | 2000-08-09 | 2002-02-14 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
WO2003079972A2 (en) | 2002-02-22 | 2003-10-02 | New River Parmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
US7601846B2 (en) * | 2001-06-26 | 2009-10-13 | The Regents Of The University Of California | Compounds having activity as inhibitors of apoptosis |
US20030232794A1 (en) * | 2001-06-26 | 2003-12-18 | Cottam Howard B. | Use of STAT-6 inhibitors as therapeutic agents |
ITMI20020773A1 (it) * | 2002-04-11 | 2003-10-13 | Nicox Sa | Farmaci per il trattamento dell'artrite |
TW200400818A (en) | 2002-05-21 | 2004-01-16 | Wyeth Corp | Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus |
TW200400963A (en) | 2002-05-21 | 2004-01-16 | Wyeth Corp | R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease |
WO2004026116A2 (en) * | 2002-09-19 | 2004-04-01 | The Regents Of The University Of California | Use of etodoclac to treat hyperplasia |
DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
CA2540289A1 (en) * | 2003-10-02 | 2005-04-14 | Cephalon, Inc. | Substituted indole derivatives |
JP2008512496A (ja) * | 2004-09-10 | 2008-04-24 | ワイス | 1,3,4,9−テトラヒドロピラノ[3,4−b]インドール誘導体の大規模実施可能な合成方法 |
EP1683521A1 (en) * | 2005-01-21 | 2006-07-26 | Centre National De La Recherche Scientifique (Cnrs) | Peptide deformylase inhibitors, their use, and pharmaceutical compositions containing the same |
DK2026651T3 (da) | 2006-03-08 | 2013-07-08 | Cortria Corp | Kombinationsterapi med ikke-selektive COX-inhibitorer til forebyggelse af COX-relaterede maveskader |
AU2009274569C1 (en) * | 2008-07-23 | 2015-06-25 | Arena Pharmaceuticals, Inc. | Substituted 1,2,3,4- tetrahydrocyclopenta[b]indol-3-yl) acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders |
-
1971
- 1971-06-01 US US00148895A patent/US3843681A/en not_active Expired - Lifetime
-
1972
- 1972-05-16 ZA ZA723344A patent/ZA723344B/xx unknown
- 1972-05-17 IL IL39466A patent/IL39466A/xx unknown
- 1972-05-22 AU AU42554/72A patent/AU463079B2/en not_active Ceased
- 1972-05-24 PH PH13564A patent/PH10625A/en unknown
- 1972-05-30 FI FI1511/72A patent/FI54125C/fi active
- 1972-05-30 DE DE2226340A patent/DE2226340A1/de active Granted
- 1972-05-31 ES ES403343A patent/ES403343A1/es not_active Expired
- 1972-05-31 DK DK271972A patent/DK155328C/da not_active IP Right Cessation
- 1972-05-31 SU SU1792255A patent/SU463262A3/ru active
- 1972-05-31 CA CA143,820A patent/CA1006875A/en not_active Expired
- 1972-05-31 AR AR242297A patent/AR198787A1/es active
- 1972-05-31 CS CS3759A patent/CS178409B2/cs unknown
- 1972-05-31 SE SE7207142A patent/SE387122B/sv unknown
- 1972-06-01 GB GB2560572A patent/GB1391005A/en not_active Expired
- 1972-06-01 NL NLAANVRAGE7207408,A patent/NL173405C/xx not_active IP Right Cessation
- 1972-06-01 JP JP5474472A patent/JPS5638594B1/ja active Pending
- 1972-06-01 CH CH813372A patent/CH580101A5/xx not_active IP Right Cessation
- 1972-06-01 HU HUAE361A patent/HU169432B/hu unknown
- 1972-06-01 FR FR7219699A patent/FR2140154B1/fr not_active Expired
- 1972-06-01 BE BE784284A patent/BE784284A/xx not_active IP Right Cessation
-
1975
- 1975-03-24 PH PH16956A patent/PH11673A/en unknown
-
1978
- 1978-03-09 HK HK130/78A patent/HK13078A/xx unknown
- 1978-12-30 MY MY237/78A patent/MY7800237A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JPS5638594B1 (sv) | 1981-09-08 |
ZA723344B (en) | 1973-12-19 |
IL39466A0 (en) | 1972-07-26 |
PH11673A (en) | 1978-05-19 |
CS178409B2 (sv) | 1977-09-15 |
SU463262A3 (ru) | 1975-03-05 |
MY7800237A (en) | 1978-12-31 |
NL7207408A (sv) | 1972-12-05 |
PH10625A (en) | 1977-07-21 |
GB1391005A (en) | 1975-04-16 |
FR2140154B1 (sv) | 1976-04-16 |
IL39466A (en) | 1975-05-22 |
NL173405C (nl) | 1984-01-16 |
DE2226340C2 (sv) | 1987-07-16 |
BE784284A (fr) | 1972-12-01 |
DE2226340A1 (de) | 1973-03-15 |
CA1006875A (en) | 1977-03-15 |
US3843681A (en) | 1974-10-22 |
FI54125C (fi) | 1978-10-10 |
AU4255472A (en) | 1973-11-29 |
HU169432B (sv) | 1976-11-28 |
AU463079B2 (en) | 1975-07-17 |
DK155328C (da) | 1989-09-18 |
FI54125B (fi) | 1978-06-30 |
DK155328B (da) | 1989-03-28 |
ES403343A1 (es) | 1975-04-16 |
HK13078A (en) | 1978-03-17 |
CH580101A5 (sv) | 1976-09-30 |
FR2140154A1 (sv) | 1973-01-12 |
AR198787A1 (es) | 1974-07-24 |
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