SE355801B - - Google Patents

Info

Publication number: SE355801B
Authority: SE; Sweden

Application number

SE16038/69A

Inventor

G Saucy

J Scott

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1968-11-22

Filing date

1969-11-21

Publication date

1973-05-07

1969-11-21 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1973-05-07 Publication of SE355801B publication Critical patent/SE355801B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
- C07J15/005—Retrosteroids (9 beta 10 alfa)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

SE16038/69A 1968-11-22 1969-11-21 SE355801B (xx)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US77831468A	1968-11-22	1968-11-22

Publications (1)

Publication Number	Publication Date
SE355801B true SE355801B (xx)	1973-05-07

Family

ID=25112933

Family Applications (5)

Application Number	Title	Priority Date
SE16036/69A SE364715B (xx)	1968-11-22	1969-11-21
SE7209181A SE376422B (xx)	1968-11-22	1969-11-21
SE16039/69A SE354657B (xx)	1968-11-22	1969-11-21
SE16037/69A SE361887B (xx)	1968-11-22	1969-11-21
SE16038/69A SE355801B (xx)	1968-11-22	1969-11-21

Family Applications Before (4)

Application Number	Title	Priority Date
SE16036/69A SE364715B (xx)	1968-11-22	1969-11-21
SE7209181A SE376422B (xx)	1968-11-22	1969-11-21
SE16039/69A SE354657B (xx)	1968-11-22	1969-11-21
SE16037/69A SE361887B (xx)	1968-11-22	1969-11-21

Country Status (19)

Country	Link
US (1)	US3700661A (xx)
JP (1)	JPS5022031B1 (xx)
AT (8)	AT308981B (xx)
BE (4)	BE742088A (xx)
BR (4)	BR6914373D0 (xx)
CA (2)	CA918669A (xx)
CH (10)	CH529774A (xx)
DE (3)	DE1958608A1 (xx)
DK (4)	DK129090B (xx)
ES (5)	ES373752A1 (xx)
FI (1)	FI47572C (xx)
FR (4)	FR2024918A1 (xx)
GB (9)	GB1298216A (xx)
IE (1)	IE33651B1 (xx)
IL (2)	IL33369A (xx)
NL (4)	NL6917499A (xx)
NO (1)	NO133806C (xx)
PH (2)	PH10667A (xx)
SE (5)	SE364715B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3984428A (en) *	1968-11-22	1976-10-05	Hoffmann-La Roche Inc.	Isoxazolyl-substituted perhydrobenzindenes
US3994930A (en) *	1970-08-26	1976-11-30	Hoffmann-La Roche Inc.	6-(3-Cyanopropyl)-2-vinyl tetrahydropyran-2-ol and its tautomer
US3991084A (en) *	1970-08-26	1976-11-09	Hoffmann-La Roche Inc.	Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor
US3873561A (en) *	1972-06-05	1975-03-25	Hoffmann La Roche	7-(4-Isoxazolyl)-5-oxo-heptanals
US3873562A (en) *	1972-06-05	1975-03-25	Hoffmann La Roche	1-(4-Isoxazolyl)-7-hydroxy-3-heptanones
US3900491A (en) *	1972-06-05	1975-08-19	Hoffmann La Roche	1-(4-isoxazolyl)-7-hydroxy-2-hydroxyimino heptanes
US3994926A (en) *	1973-05-24	1976-11-30	Hoffmann-La Roche Inc.	Aryl ketals of polycyclic oxo compounds and processes
US3855209A (en) *	1973-09-04	1974-12-17	Eastman Kodak Co	Synthesis of indolininium methine dyes
US4054583A (en) *	1976-07-06	1977-10-18	Eli Lilly And Company	Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one
US6030970A (en) *	1995-08-02	2000-02-29	Smithkline Beecham Corporation	Endothelin receptor antagonists
JPH11513022A (ja) *	1995-08-02	1999-11-09	スミスクライン・ビーチャム・コーポレイション	エンドセリンレセプターアンタゴニスト
JP2000504013A (ja) *	1996-02-01	2000-04-04	スミスクライン・ビーチャム・コーポレイション	エンドセリンレセプターアンタゴニスト
US6174906B1 (en)	1999-10-01	2001-01-16	Smithkline Beecham Corporation	Endothelin receptor antagonists

1968
- 1968-11-22 US US778314A patent/US3700661A/en not_active Expired - Lifetime
1969
- 1969-11-12 CH CH1679469A patent/CH529774A/de not_active IP Right Cessation
- 1969-11-12 CH CH350272A patent/CH537938A/de not_active IP Right Cessation
- 1969-11-12 CH CH350372A patent/CH537942A/de not_active IP Right Cessation
- 1969-11-14 CH CH217472A patent/CH568314A5/xx not_active IP Right Cessation
- 1969-11-14 CH CH1695669A patent/CH561192A5/xx not_active IP Right Cessation
- 1969-11-14 CH CH217272A patent/CH567489A5/xx not_active IP Right Cessation
- 1969-11-14 CA CA067476A patent/CA918669A/en not_active Expired
- 1969-11-14 CH CH217372A patent/CH567490A5/xx not_active IP Right Cessation
- 1969-11-17 IL IL33369A patent/IL33369A/en unknown
- 1969-11-18 CH CH1710469A patent/CH567523A5/xx not_active IP Right Cessation
- 1969-11-18 CH CH107372A patent/CH578547A5/xx not_active IP Right Cessation
- 1969-11-19 CH CH1719469A patent/CH574890A5/xx not_active IP Right Cessation
- 1969-11-20 GB GB00793/71A patent/GB1298216A/en not_active Expired
- 1969-11-20 CA CA067,962A patent/CA944770A/en not_active Expired
- 1969-11-20 GB GB56793/63A patent/GB1298214A/en not_active Expired
- 1969-11-20 GB GB56792/69A patent/GB1298213A/en not_active Expired
- 1969-11-20 NL NL6917499A patent/NL6917499A/xx unknown
- 1969-11-20 GB GB28140/71A patent/GB1298219A/en not_active Expired
- 1969-11-20 GB GB28139/71A patent/GB1298218A/en not_active Expired
- 1969-11-20 DK DK617269AA patent/DK129090B/da unknown
- 1969-11-20 GB GB28138/71A patent/GB1298217A/en not_active Expired
- 1969-11-20 GB GB56791/69A patent/GB1298212A/en not_active Expired
- 1969-11-20 GB GB00792/71A patent/GB1298215A/en not_active Expired
- 1969-11-20 DK DK617169AA patent/DK130117B/da unknown
- 1969-11-20 GB GB56790/69A patent/GB1298211A/en not_active Expired
- 1969-11-21 IE IE1575/69A patent/IE33651B1/xx unknown
- 1969-11-21 FI FI693380A patent/FI47572C/fi active
- 1969-11-21 NL NL6917574A patent/NL6917574A/xx unknown
- 1969-11-21 AT AT464671A patent/AT308981B/de active
- 1969-11-21 AT AT899970A patent/AT294832B/de not_active IP Right Cessation
- 1969-11-21 FR FR6940170A patent/FR2024918A1/fr not_active Withdrawn
- 1969-11-21 SE SE16036/69A patent/SE364715B/xx unknown
- 1969-11-21 AT AT877370A patent/AT292695B/de not_active IP Right Cessation
- 1969-11-21 DE DE19691958608 patent/DE1958608A1/de active Pending
- 1969-11-21 NO NO4629/69A patent/NO133806C/no unknown
- 1969-11-21 AT AT1088969A patent/AT292694B/de not_active IP Right Cessation
- 1969-11-21 BR BR214373/69A patent/BR6914373D0/pt unknown
- 1969-11-21 SE SE7209181A patent/SE376422B/xx unknown
- 1969-11-21 FR FR6940171A patent/FR2024919A1/fr not_active Withdrawn
- 1969-11-21 BR BR214372/69A patent/BR6914372D0/pt unknown
- 1969-11-21 DE DE1958600A patent/DE1958600C3/de not_active Expired
- 1969-11-21 SE SE16039/69A patent/SE354657B/xx unknown
- 1969-11-21 SE SE16037/69A patent/SE361887B/xx unknown
- 1969-11-21 BR BR214374/69A patent/BR6914374D0/pt unknown
- 1969-11-21 AT AT877270A patent/AT299463B/de not_active IP Right Cessation
- 1969-11-21 DE DE19691958601 patent/DE1958601A1/de active Pending
- 1969-11-21 BR BR214375/69A patent/BR6914375D0/pt unknown
- 1969-11-21 FR FR6940172A patent/FR2030078A1/fr not_active Withdrawn
- 1969-11-21 SE SE16038/69A patent/SE355801B/xx unknown
- 1969-11-21 ES ES373752A patent/ES373752A1/es not_active Expired
- 1969-11-21 AT AT1089069A patent/AT294331B/de not_active IP Right Cessation
- 1969-11-21 ES ES373751A patent/ES373751A1/es not_active Expired
- 1969-11-21 ES ES373753A patent/ES373753A1/es not_active Expired
- 1969-11-21 NL NL6917557A patent/NL6917557A/xx not_active Application Discontinuation
- 1969-11-21 AT AT1089169A patent/AT304772B/de not_active IP Right Cessation
- 1969-11-21 FR FR6940173A patent/FR2024920A1/fr not_active Withdrawn
- 1969-11-21 NL NL6917554A patent/NL6917554A/xx unknown
- 1969-11-21 AT AT1089269A patent/AT295757B/de not_active IP Right Cessation
- 1969-11-22 JP JP44093897A patent/JPS5022031B1/ja active Pending
- 1969-11-22 ES ES373754A patent/ES373754A1/es not_active Expired
- 1969-11-24 BE BE742088D patent/BE742088A/xx unknown
- 1969-11-24 BE BE742089D patent/BE742089A/xx unknown
- 1969-11-24 BE BE742090D patent/BE742090A/xx unknown
- 1969-11-24 BE BE742087D patent/BE742087A/xx unknown
1971
- 1971-08-12 DK DK394671AA patent/DK126655B/da unknown
1972
- 1972-02-04 DK DK50772AA patent/DK127975B/da unknown
- 1972-04-21 ES ES401968A patent/ES401968A1/es not_active Expired
1973
- 1973-05-28 IL IL42366A patent/IL42366A0/xx unknown
- 1973-08-27 PH PH14967A patent/PH10667A/en unknown
- 1973-08-27 PH PH14968A patent/PH11342A/en unknown

Also Published As

Publication number	Publication date
FR2024919A1 (xx)	1970-09-04
CH567490A5 (xx)	1975-10-15
GB1298217A (en)	1972-11-29
CH529774A (de)	1972-10-31
GB1298213A (en)	1972-11-29
FR2030078A1 (xx)	1970-10-30
GB1298219A (en)	1972-11-29
BE742087A (xx)	1970-05-25
CH567523A5 (xx)	1975-10-15
IL42366A0 (en)	1973-07-30
AT292694B (de)	1971-09-10
DK129090B (da)	1974-08-19
DE1958600A1 (de)	1970-07-09
BR6914373D0 (pt)	1973-02-08
CA944770A (en)	1974-04-02
NO133806C (xx)	1976-06-30
DE1958600C3 (de)	1980-08-07
SE354657B (xx)	1973-03-19
BE742089A (xx)	1970-05-25
NO133806B (xx)	1976-03-22
CA918669A (en)	1973-01-09
BR6914374D0 (pt)	1973-04-19
CH568314A5 (xx)	1975-10-31
NL6917499A (xx)	1970-05-26
DK130117B (da)	1974-12-23
FI47572C (fi)	1974-01-10
IL33369A0 (en)	1970-01-29
DK127975B (da)	1974-02-11
PH11342A (en)	1977-11-02
JPS5022031B1 (xx)	1975-07-28
FR2024920A1 (xx)	1970-09-04
BR6914375D0 (pt)	1973-04-19
DE1958600B2 (de)	1979-11-29
GB1298211A (en)	1972-11-29
FI47572B (xx)	1973-10-01
AT292695B (de)	1971-09-10
CH567489A5 (xx)	1975-10-15
DE1958608A1 (de)	1970-06-18
CH561192A5 (xx)	1975-04-30
US3700661A (en)	1972-10-24
CH537942A (de)	1973-07-31
CH578547A5 (xx)	1976-08-13
ES401968A1 (es)	1976-04-16
IL33369A (en)	1973-10-25
GB1298215A (en)	1972-11-29
GB1298214A (en)	1972-11-29
AT295757B (de)	1972-01-25
AT294331B (de)	1971-11-25
BR6914372D0 (pt)	1973-02-08
CH537938A (de)	1973-07-31
BE742090A (xx)	1970-05-25
GB1298218A (en)	1972-11-29
NL6917557A (xx)	1970-05-26
DE1958601A1 (de)	1970-06-18
SE376422B (xx)	1975-05-26
ES373753A1 (es)	1973-04-16
PH10667A (en)	1977-08-02
DK126655B (da)	1973-08-06
NL6917554A (xx)	1970-05-26
ES373754A1 (es)	1972-04-01
DK130117C (xx)	1975-06-09
AT304772B (de)	1973-01-25
FR2024918A1 (xx)	1970-09-04
ES373752A1 (es)	1973-04-16
AT308981B (de)	1973-07-25
SE364715B (xx)	1974-03-04
GB1298212A (en)	1972-11-29
AT294832B (de)	1971-12-10
ES373751A1 (es)	1972-02-01
IE33651L (en)	1970-05-22
IE33651B1 (en)	1974-09-18
GB1298216A (en)	1972-11-29
SE361887B (xx)	1973-11-19
AT299463B (de)	1972-06-26
BE742088A (xx)	1970-05-25
CH574890A5 (xx)	1976-04-30
NL6917574A (xx)	1970-05-26

Publication	Publication Date	Title
DK130117C (xx)	1975-06-09
AU3789668A (xx)	1968-06-20
BE709479A (xx)	1968-07-17
BE726784A (xx)	1969-07-14
BE726782A (xx)	1969-06-16
BE726551A (xx)	1969-06-16
BE724436A (xx)	1969-05-02
BE724424A (xx)	1969-05-02
BE721690A (xx)	1969-03-14
BE717145A (xx)	1968-12-02
BE709496A (xx)	1968-07-17
BE709484A (xx)	1968-05-30
BE709095A (xx)	1968-07-09
BE709446A (xx)	1968-05-30
BE709435A (xx)	1968-07-16
BE709415A (xx)	1968-05-30
BE709320A (xx)	1968-05-16
BE709319A (xx)	1968-05-16
BE709301A (xx)	1968-07-12
BE709274A (xx)	1968-07-12
AU3083868A (xx)	1969-10-30
BE727107A (xx)	1969-07-01
BE709119A (xx)	1968-05-16
BE708951A (xx)	1968-05-16
BE727140A (xx)	1969-07-01