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SE0301653D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0301653D0
SE0301653D0 SE0301653A SE0301653A SE0301653D0 SE 0301653 D0 SE0301653 D0 SE 0301653D0 SE 0301653 A SE0301653 A SE 0301653A SE 0301653 A SE0301653 A SE 0301653A SE 0301653 D0 SE0301653 D0 SE 0301653D0
Authority
SE
Sweden
Prior art keywords
novel compounds
therapy
processes
preparation
pharmaceutical compositions
Prior art date
Application number
SE0301653A
Other languages
English (en)
Inventor
Antonio Mete
Richard Harrison
Lain Walters
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0301653A priority Critical patent/SE0301653D0/sv
Publication of SE0301653D0 publication Critical patent/SE0301653D0/sv
Priority to TW093115166A priority patent/TW200505875A/zh
Priority to PCT/SE2004/000850 priority patent/WO2004108692A1/en
Priority to DE602004015451T priority patent/DE602004015451D1/de
Priority to AT04748975T priority patent/ATE402928T1/de
Priority to ES04748975T priority patent/ES2309539T3/es
Priority to JP2006508570A priority patent/JP2006526618A/ja
Priority to US10/559,312 priority patent/US20060122195A1/en
Priority to EP04748975A priority patent/EP1633729B1/en
Priority to UY28348A priority patent/UY28348A1/es
Priority to ARP040101943A priority patent/AR044614A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
    • C07D241/22—Benzenesulfonamido pyrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
SE0301653A 2003-06-05 2003-06-05 Novel compounds SE0301653D0 (sv)

Priority Applications (11)

Application Number Priority Date Filing Date Title
SE0301653A SE0301653D0 (sv) 2003-06-05 2003-06-05 Novel compounds
TW093115166A TW200505875A (en) 2003-06-05 2004-05-27 Novel compounds
EP04748975A EP1633729B1 (en) 2003-06-05 2004-06-02 Sulphonamide compounds that modulate chemokine receptor activity (ccr4)
AT04748975T ATE402928T1 (de) 2003-06-05 2004-06-02 Sulphonamidverbindungen, die die chemokinrezeptoraktivität (ccr4) modulieren
DE602004015451T DE602004015451D1 (de) 2003-06-05 2004-06-02 Sulphonamidverbindungen, die die chemokinrezeptoraktivität (ccr4) modulieren
PCT/SE2004/000850 WO2004108692A1 (en) 2003-06-05 2004-06-02 Sulphonamide compounds that modulate chemokine receptor activity (ccr4)
ES04748975T ES2309539T3 (es) 2003-06-05 2004-06-02 Compuestos de sulfonamida que modulan la actividad de los receptores de la quimioquina (ccr4).
JP2006508570A JP2006526618A (ja) 2003-06-05 2004-06-02 ケモカイン受容体活性（ｃｃｒ４）をモジュレーションするスルホンアミド化合物
US10/559,312 US20060122195A1 (en) 2003-06-05 2004-06-02 Sulphonamide compounds that modulate chemokine receptor activity (ccr4)
UY28348A UY28348A1 (es) 2003-06-05 2004-06-04 Compuestos novedosos
ARP040101943A AR044614A1 (es) 2003-06-05 2004-06-04 Composiciones de sulfonamida que modulan la actividad del receptor de quinioquinas (ccr4)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0301653A SE0301653D0 (sv) 2003-06-05 2003-06-05 Novel compounds

Publications (1)

Publication Number Publication Date
SE0301653D0 true SE0301653D0 (sv) 2003-06-05

Family

ID=29212392

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0301653A SE0301653D0 (sv) 2003-06-05 2003-06-05 Novel compounds

Country Status (11)

Country Link
US (1) US20060122195A1 (sv)
EP (1) EP1633729B1 (sv)
JP (1) JP2006526618A (sv)
AR (1) AR044614A1 (sv)
AT (1) ATE402928T1 (sv)
DE (1) DE602004015451D1 (sv)
ES (1) ES2309539T3 (sv)
SE (1) SE0301653D0 (sv)
TW (1) TW200505875A (sv)
UY (1) UY28348A1 (sv)
WO (1) WO2004108692A1 (sv)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI328007B (en) * 2002-01-16 2010-08-01 Astrazeneca Ab Novel compounds
SE0301650D0 (sv) * 2003-06-04 2003-06-04 Astrazeneca Ab Novel compounds
SE0301654D0 (sv) * 2003-06-05 2003-06-05 Astrazeneca Ab Novel compounds
US8796280B2 (en) 2005-04-21 2014-08-05 Merck Serono, S.A. 2,3-disubstituted pyrazinesulfonamides as CRTH2 inhibitors
NZ562772A (en) 2005-05-24 2010-01-29 Serono Lab Tricyclic spiro derivatives as CRTH2 modulators
TW200800921A (en) * 2005-09-19 2008-01-01 Astrazeneca Ab Novel compounds
TW200745060A (en) * 2005-09-19 2007-12-16 Astrazeneca Ab Novel process
US20090182140A1 (en) * 2005-12-02 2009-07-16 Mitsubishi Tanabe Pharma Corporation Alicyclic Heterocyclic Compound
US20090182142A1 (en) * 2005-12-02 2009-07-16 Shigeru Furukubo Aromatic Compound
TW200730512A (en) * 2005-12-12 2007-08-16 Astrazeneca Ab Novel compounds
US7829709B1 (en) 2007-08-10 2010-11-09 Marquette University Cysteine prodrugs to treat schizophrenia and drug addiction
GB0718167D0 (en) 2007-09-18 2007-10-31 Cancer Rec Tech Ltd Cancer marker and therapeutic target
EP2252596B1 (en) 2008-02-07 2016-12-28 Marquette University Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings
JP5658137B2 (ja) * 2008-04-16 2015-01-21 マーケット ユニバーシティー 統合失調症又は薬物渇望治療用医薬組成物
JP5785560B2 (ja) 2009-12-21 2015-09-30 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 殺真菌剤としてのビス（ジフルオロメチル）ピラゾール
US8815775B2 (en) 2010-05-18 2014-08-26 Bayer Cropscience Ag Bis(difluoromethyl)pyrazoles as fungicides
US8916601B2 (en) 2012-02-29 2014-12-23 Chemocentryx, Inc. Aza-aryl 1H-pyrazol-1-YL benzene sulfonamides
AU2015217073B2 (en) 2014-02-13 2019-08-22 Incyte Holdings Corporation Cyclopropylamines as LSD1 inhibitors
US9527835B2 (en) 2014-02-13 2016-12-27 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
US9493442B2 (en) 2014-02-13 2016-11-15 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
ME03580B (me) 2014-02-13 2020-07-20 Incyte Corp Ciklopropilamini kao lsd1 inhibitori
WO2016007736A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Imidazopyrazines as lsd1 inhibitors
TWI687419B (zh) 2014-07-10 2020-03-11 美商英塞特公司 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪
US9695167B2 (en) 2014-07-10 2017-07-04 Incyte Corporation Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors
WO2016007727A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
EP3204424B1 (en) 2014-10-06 2023-11-29 ChemoCentryx, Inc. Combination therapy of c-c chemokine receptor-9 (ccr9) inhibitors and anti-alpha4beta7 integrin blocking antibodies for the treatment of inflammatory bowel disease
EP3277689B1 (en) 2015-04-03 2019-09-04 Incyte Corporation Heterocyclic compounds as lsd1 inhibitors
PE20181175A1 (es) 2015-08-12 2018-07-20 Incyte Corp Sales de un inhibidor de lsd1
AU2017252328B2 (en) 2016-04-22 2023-02-23 Incyte Corporation Formulations of an LSD1 inhibitor
CN111918652A (zh) 2017-11-06 2020-11-10 拉普特医疗公司 用于治疗eb病毒阳性的癌症的趋化因子受体调节剂
US10968200B2 (en) 2018-08-31 2021-04-06 Incyte Corporation Salts of an LSD1 inhibitor and processes for preparing the same
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) * 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
GB9512697D0 (en) * 1995-06-22 1995-08-23 Zeneca Ltd Heterocyclic compounds
JP2004509874A (ja) * 2000-09-25 2004-04-02 アクテリオン　ファマシューティカルズ　リミテッド 新規なアリールアルカン−スルフォンアミド類
US20020132836A1 (en) * 2000-10-11 2002-09-19 Chemocentryx Inc. Compounds and methods for modulating CCR4 function
WO2003051870A1 (en) * 2001-12-18 2003-06-26 Astrazeneca Ab Novel compounds
TWI328007B (en) * 2002-01-16 2010-08-01 Astrazeneca Ab Novel compounds
AU2003252478A1 (en) * 2002-07-10 2004-02-02 Ono Pharmaceutical Co., Ltd. Ccr4 antagonist and medicinal use thereof
SE0301650D0 (sv) * 2003-06-04 2003-06-04 Astrazeneca Ab Novel compounds
SE0301654D0 (sv) * 2003-06-05 2003-06-05 Astrazeneca Ab Novel compounds

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