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SE0104125D0 - High sensitivity protein workstation and techniques - Google Patents

High sensitivity protein workstation and techniques

Info

Publication number
SE0104125D0
SE0104125D0 SE0104125A SE0104125A SE0104125D0 SE 0104125 D0 SE0104125 D0 SE 0104125D0 SE 0104125 A SE0104125 A SE 0104125A SE 0104125 A SE0104125 A SE 0104125A SE 0104125 D0 SE0104125 D0 SE 0104125D0
Authority
SE
Sweden
Prior art keywords
bio
molecules
sample
amplified
workstation
Prior art date
Application number
SE0104125A
Other languages
English (en)
Inventor
Thomas Laurell
Gyoergy Marko-Varga
Johan Nilsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0104125A priority Critical patent/SE0104125D0/sv
Publication of SE0104125D0 publication Critical patent/SE0104125D0/sv
Priority to SE0202226A priority patent/SE0202226D0/sv
Priority to SE0202225A priority patent/SE0202225D0/sv
Priority to SE0202224A priority patent/SE0202224D0/sv
Priority to SE0202227A priority patent/SE0202227D0/sv
Priority to SE0202223A priority patent/SE0202223D0/sv
Priority to SE0202222A priority patent/SE0202222D0/sv
Priority to SE0202228A priority patent/SE0202228D0/sv
Priority to SE0202397A priority patent/SE0202397D0/sv
Priority to SE0202401A priority patent/SE0202401D0/sv
Priority to SE0202415A priority patent/SE0202415D0/sv
Priority to SE0202399A priority patent/SE0202399D0/sv
Priority to SE0202398A priority patent/SE0202398D0/sv
Priority to SE0202400A priority patent/SE0202400D0/sv
Priority to AU2002359111A priority patent/AU2002359111A1/en
Priority to AU2002359112A priority patent/AU2002359112A1/en
Priority to CA002469930A priority patent/CA2469930A1/en
Priority to AU2002359113A priority patent/AU2002359113A1/en
Priority to PCT/SE2002/002285 priority patent/WO2003053555A2/en
Priority to CA002469936A priority patent/CA2469936A1/en
Priority to JP2003555216A priority patent/JP2005513482A/ja
Priority to CA002469932A priority patent/CA2469932A1/en
Priority to AU2002359114A priority patent/AU2002359114B2/en
Priority to US10/498,072 priority patent/US20050048568A1/en
Priority to EP02793618A priority patent/EP1461595A1/en
Priority to AU2002360234A priority patent/AU2002360234A1/en
Priority to EP02795471A priority patent/EP1461144A2/en
Priority to JP2003554310A priority patent/JP4142587B2/ja
Priority to CA002469937A priority patent/CA2469937A1/en
Priority to PCT/SE2002/002286 priority patent/WO2003054554A1/en
Priority to AU2002359110A priority patent/AU2002359110A1/en
Priority to PCT/SE2002/002282 priority patent/WO2003054553A1/en
Priority to JP2003554290A priority patent/JP2005513452A/ja
Priority to US10/498,194 priority patent/US20050032202A1/en
Priority to US10/498,073 priority patent/US20050047962A1/en
Priority to US10/498,212 priority patent/US20050029440A1/en
Priority to EP02793619A priority patent/EP1461622A2/en
Priority to PCT/SE2002/002284 priority patent/WO2003054915A1/en
Priority to US10/497,992 priority patent/US20050042769A1/en
Priority to EP02792133A priority patent/EP1461130A2/en
Priority to PCT/SE2002/002281 priority patent/WO2003053582A2/en
Priority to US10/497,996 priority patent/US20050070010A1/en
Priority to EP02793622A priority patent/EP1461623A1/en
Priority to AU2002358377A priority patent/AU2002358377A1/en
Priority to CA002469931A priority patent/CA2469931A1/en
Priority to AU2002360233A priority patent/AU2002360233A1/en
Priority to US10/498,043 priority patent/US20050031496A1/en
Priority to AU2002358371A priority patent/AU2002358371A1/en
Priority to PCT/SE2002/002279 priority patent/WO2003053581A2/en
Priority to PCT/SE2002/002283 priority patent/WO2003053534A2/en
Priority to JP2003554334A priority patent/JP2005513453A/ja
Priority to EP02793621A priority patent/EP1461822A1/en
Priority to PCT/SE2002/002305 priority patent/WO2003054505A2/en
Priority to JP2003555544A priority patent/JP2005513490A/ja
Priority to JP2003555182A priority patent/JP2005513472A/ja
Priority to JP2003554335A priority patent/JP2005513454A/ja
Priority to EP02795470A priority patent/EP1455941A2/en
Priority to PCT/SE2002/002280 priority patent/WO2003054518A1/en
Priority to CA002469933A priority patent/CA2469933A1/en
Priority to CA002469841A priority patent/CA2469841A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44769—Continuous electrophoresis, i.e. the sample being continuously introduced, e.g. free flow electrophoresis [FFE]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
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    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
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    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
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    • G01—MEASURING; TESTING
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    • G01N1/40—Concentrating samples
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    • G01N2035/1053—General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Electrochemistry (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SE0104125A 2001-12-11 2001-12-11 High sensitivity protein workstation and techniques SE0104125D0 (sv)

Priority Applications (60)

Application Number Priority Date Filing Date Title
SE0104125A SE0104125D0 (sv) 2001-12-11 2001-12-11 High sensitivity protein workstation and techniques
SE0202226A SE0202226D0 (sv) 2001-12-11 2002-07-15 Analysis machine and method
SE0202225A SE0202225D0 (sv) 2001-12-11 2002-07-15 Generic array dispenser
SE0202224A SE0202224D0 (sv) 2001-12-11 2002-07-15 Device and method useable for integrated sequential separation and enrichment of proteins
SE0202227A SE0202227D0 (sv) 2001-12-11 2002-07-15 Biomolecule handling method and machine using an array dispenser
SE0202223A SE0202223D0 (sv) 2001-12-11 2002-07-15 Target plate and use thereof for improved analysis
SE0202222A SE0202222D0 (sv) 2001-12-11 2002-07-15 Dockable processing module
SE0202228A SE0202228D0 (sv) 2001-12-11 2002-07-15 FFE array dispenser
SE0202397A SE0202397D0 (sv) 2001-12-11 2002-08-13 Generic array dispenser
SE0202401A SE0202401D0 (sv) 2001-12-11 2002-08-13 Biomolecule handling method and machine using an arry dispenser
SE0202415A SE0202415D0 (sv) 2001-12-11 2002-08-13 Dockable processing module
SE0202399A SE0202399D0 (sv) 2001-12-11 2002-08-13 Device and method useable for integrated sequential separation and enrichment of proteins
SE0202398A SE0202398D0 (sv) 2001-12-11 2002-08-13 Target plate and use thereof for improved analysis
SE0202400A SE0202400D0 (sv) 2001-12-11 2002-08-13 FFE Array dispenser
AU2002359111A AU2002359111A1 (en) 2001-12-11 2002-12-11 Ffe array dispenser
AU2002359112A AU2002359112A1 (en) 2001-12-11 2002-12-11 Generic array dispenser with laminar virtual flow channels
CA002469930A CA2469930A1 (en) 2001-12-11 2002-12-11 Biomolecule handling method and machine using an array dispenser
AU2002359113A AU2002359113A1 (en) 2001-12-11 2002-12-11 Target plate for mass spectometers and use thereof
PCT/SE2002/002285 WO2003053555A2 (en) 2001-12-11 2002-12-11 Dockable processing module for extracting molecules from a solution
CA002469936A CA2469936A1 (en) 2001-12-11 2002-12-11 Dockable processing module for extracting molecules from a solution
JP2003555216A JP2005513482A (ja) 2001-12-11 2002-12-11 高感度タンパク質ワークステーション及びその技術
CA002469932A CA2469932A1 (en) 2001-12-11 2002-12-11 Ffe array dispenser
AU2002359114A AU2002359114B2 (en) 2001-12-11 2002-12-11 High sensitivity protein workstation and techniques
US10/498,072 US20050048568A1 (en) 2001-12-11 2002-12-11 High sensitivity protein workstation and techniques
EP02793618A EP1461595A1 (en) 2001-12-11 2002-12-11 Machine and method for processing biomolecules
AU2002360234A AU2002360234A1 (en) 2001-12-11 2002-12-11 Dockable processing module for extracting molecules from a solution
EP02795471A EP1461144A2 (en) 2001-12-11 2002-12-11 Dockable processing module
JP2003554310A JP4142587B2 (ja) 2001-12-11 2002-12-11 溶液から分子を抽出するための合体可能なプロセシングモジュール
CA002469937A CA2469937A1 (en) 2001-12-11 2002-12-11 High sensitivity protein workstation and techniques
PCT/SE2002/002286 WO2003054554A1 (en) 2001-12-11 2002-12-11 High sensitivity protein workstation and techniques
AU2002359110A AU2002359110A1 (en) 2001-12-11 2002-12-11 Machine and method for processing biomolecules
PCT/SE2002/002282 WO2003054553A1 (en) 2001-12-11 2002-12-11 Generic array dispenser with laminar virtual flow channels
JP2003554290A JP2005513452A (ja) 2001-12-11 2002-12-11 タンパク質の統合型逐次分離濃縮のために使用可能なデバイスおよび方法
US10/498,194 US20050032202A1 (en) 2001-12-11 2002-12-11 Device and method useable for integrated sequential separation and enrichment of proteins
US10/498,073 US20050047962A1 (en) 2001-12-11 2002-12-11 Ffe array dispenser
US10/498,212 US20050029440A1 (en) 2001-12-11 2002-12-11 Machine and method for processing biomolecules
EP02793619A EP1461622A2 (en) 2001-12-11 2002-12-11 Ffe array dispenser
PCT/SE2002/002284 WO2003054915A1 (en) 2001-12-11 2002-12-11 Target plate for mass spectometers and use thereof
US10/497,992 US20050042769A1 (en) 2001-12-11 2002-12-11 Biomolecule handling method and machine using an array dispenser
EP02792133A EP1461130A2 (en) 2001-12-11 2002-12-11 Device and method useable for integrated sequential separation and enrichment of proteins
PCT/SE2002/002281 WO2003053582A2 (en) 2001-12-11 2002-12-11 Ffe array dispenser
US10/497,996 US20050070010A1 (en) 2001-12-11 2002-12-11 Dockable processing module
EP02793622A EP1461623A1 (en) 2001-12-11 2002-12-11 High sensitivity protein workstation and techniques
AU2002358377A AU2002358377A1 (en) 2001-12-11 2002-12-11 High sensitivity protein workstation and techniques
CA002469931A CA2469931A1 (en) 2001-12-11 2002-12-11 Machine and method for processing biomolecules
AU2002360233A AU2002360233A1 (en) 2001-12-11 2002-12-11 Biomolecule handling method and machine using an array dispenser
US10/498,043 US20050031496A1 (en) 2001-12-11 2002-12-11 Target plate for mass spectometers and use thereof
AU2002358371A AU2002358371A1 (en) 2001-12-11 2002-12-11 Device and method useable for integrated sequential separation and enrichment of proteins
PCT/SE2002/002279 WO2003053581A2 (en) 2001-12-11 2002-12-11 Biomolecule handling method and machine using an array dispenser
PCT/SE2002/002283 WO2003053534A2 (en) 2001-12-11 2002-12-11 Device and method useable for integrated sequential separation and enrichment of proteins
JP2003554334A JP2005513453A (ja) 2001-12-11 2002-12-11 アレイ・ディスペンサーを使用した生体分子の取扱い方法及び取扱い機械
EP02793621A EP1461822A1 (en) 2001-12-11 2002-12-11 Target plate for mass spectometers and use thereof
PCT/SE2002/002305 WO2003054505A2 (en) 2001-12-11 2002-12-11 High sensitivity protein workstation and techniques
JP2003555544A JP2005513490A (ja) 2001-12-11 2002-12-11 質量分析計のための標的プレート及び該標的プレートの使用
JP2003555182A JP2005513472A (ja) 2001-12-11 2002-12-11 分析機及び分析方法
JP2003554335A JP2005513454A (ja) 2001-12-11 2002-12-11 Ｆｆｅアレイディスペンサー
EP02795470A EP1455941A2 (en) 2001-12-11 2002-12-11 Biomolecule handling method and machine using an array dispenser
PCT/SE2002/002280 WO2003054518A1 (en) 2001-12-11 2002-12-11 Machine and method for processing biomolecules
CA002469933A CA2469933A1 (en) 2001-12-11 2002-12-11 Device and method useable for integrated sequential separation and enrichment of proteins
CA002469841A CA2469841A1 (en) 2001-12-11 2002-12-11 Target plate for mass spectometers and use thereof

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CN1908662B (zh) * 2006-08-15 2010-08-18 佛山分析仪有限公司 一种压电蛋白芯片的制作方法
US8763623B2 (en) * 2009-11-06 2014-07-01 Massachusetts Institute Of Technology Methods for handling solids in microfluidic systems

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US5587128A (en) * 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US6309828B1 (en) * 1998-11-18 2001-10-30 Agilent Technologies, Inc. Method and apparatus for fabricating replicate arrays of nucleic acid molecules
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US6613893B1 (en) * 2000-07-31 2003-09-02 Agilent Technologies Inc. Array fabrication
US6875402B2 (en) * 2000-10-16 2005-04-05 Ngk Insulators, Ltd. Micropipette, dispenser and method for producing biochip
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CA2469937A1 (en) 2003-07-03
AU2002359114A1 (en) 2003-07-09
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AU2002358377A1 (en) 2003-07-09
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