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RU94046312A - Use of biologically active ureido-derivatives for treatment lentivirus-induced disease, products containing ureido-derivatives - Google Patents

Use of biologically active ureido-derivatives for treatment lentivirus-induced disease, products containing ureido-derivatives

Info

Publication number
RU94046312A
RU94046312A RU94046312/14A RU94046312A RU94046312A RU 94046312 A RU94046312 A RU 94046312A RU 94046312/14 A RU94046312/14 A RU 94046312/14A RU 94046312 A RU94046312 A RU 94046312A RU 94046312 A RU94046312 A RU 94046312A
Authority
RU
Russia
Prior art keywords
derivatives
ureido
treatment
lentivirus
biologically active
Prior art date
Application number
RU94046312/14A
Other languages
Russian (ru)
Other versions
RU2142798C1 (en
Inventor
Монджелли Никола
It]
Биасоли Джованни
Гранди Мария
Чиомеи Марина
Кристина Джерони Мария
Original Assignee
Фармиталиа Карло Эрба С.р.л. (IT)
Фармиталиа Карло Эрба С.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармиталиа Карло Эрба С.р.л. (IT), Фармиталиа Карло Эрба С.Р.Л. filed Critical Фармиталиа Карло Эрба С.р.л. (IT)
Publication of RU94046312A publication Critical patent/RU94046312A/en
Application granted granted Critical
Publication of RU2142798C1 publication Critical patent/RU2142798C1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)

Abstract

FIELD: organic chemistry. SUBSTANCE: product: compound of the formula (I)where each m and n that are similar = 1-3; each of R-groups that are similar is naphthyl substituted with 1-3 sulfo-groups, or its pharmaceutically acceptable salt. Synthesized compound were used for treatment of infections caused by lentiviruses. EFFECT: improved method of synthesis, enhanced effectiveness of treatment.

Claims (1)

Для приготовления лекарственного средства, предназначенного для лечения инфекции лентивируса, предложено соединение формулы, приведенной в описании, или его фармацевтически приемлемая соль.For the preparation of a medicinal product intended for the treatment of lentivirus infection, a compound of the formula described in the description or a pharmaceutically acceptable salt thereof is provided.
RU94046312A 1993-04-16 1994-03-29 Agent based on biologically active ureido-derivatives for treatment of patients with infections caused by lentivirus RU2142798C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939307948A GB9307948D0 (en) 1993-04-16 1993-04-16 Biologically active ureido derivatives useful in the treatment of lentivirus-induced disease
GB9307948.1 1993-04-16
PCT/EP1994/000984 WO1994023718A1 (en) 1993-04-16 1994-03-29 Biologically active ureido derivatives useful in the treatment of lentivirus-induced disease

Publications (2)

Publication Number Publication Date
RU94046312A true RU94046312A (en) 1996-10-20
RU2142798C1 RU2142798C1 (en) 1999-12-20

Family

ID=10733998

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94046312A RU2142798C1 (en) 1993-04-16 1994-03-29 Agent based on biologically active ureido-derivatives for treatment of patients with infections caused by lentivirus

Country Status (15)

Country Link
EP (1) EP0646004A1 (en)
JP (1) JPH07508044A (en)
KR (1) KR950701812A (en)
AU (1) AU670194B2 (en)
CA (1) CA2137148A1 (en)
CZ (1) CZ282988B6 (en)
GB (1) GB9307948D0 (en)
HU (1) HU216834B (en)
IL (1) IL109235A (en)
NO (1) NO307126B1 (en)
PL (1) PL306798A1 (en)
RU (1) RU2142798C1 (en)
TW (1) TW308593B (en)
UA (1) UA42693C2 (en)
WO (1) WO1994023718A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9504065D0 (en) * 1995-03-01 1995-04-19 Pharmacia Spa Poly-pyrrolecarboxamidonaphthalenic acid derivatives
GB9602721D0 (en) * 1996-02-09 1996-04-10 Pharmacia Spa Biologically active ureido derivatives useful in the treatment of multiple sclerosis
GB2310207A (en) * 1996-02-15 1997-08-20 Pharmacia Spa Antiviral ureido derivatives of substituted heterocyclic compounds
GB9713733D0 (en) * 1997-06-27 1997-09-03 Pharmacia & Upjohn Spa Poly-branched polycarboxamido compounds
EP3381897A1 (en) 2017-03-27 2018-10-03 Leadiant Biosciences SA Derivatives of the disodium 2,2'-{carbonylbis[imino-3,1-phenylenecarbonylimino(1-methyl-1h-pyrrole-4,2-diyl)carbonylimino]}dinaphthalene-1,5-disulfonate salt and related compounds as heparanase inhibitors for the treatment of cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9000644D0 (en) * 1990-01-11 1990-03-14 Erba Carlo Spa New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds
CA2103665C (en) * 1991-02-06 2003-04-15 J. William Lown Oligopeptide antiretroviral agents

Also Published As

Publication number Publication date
HU216834B (en) 1999-09-28
WO1994023718A1 (en) 1994-10-27
KR950701812A (en) 1995-05-17
RU2142798C1 (en) 1999-12-20
HUT71838A (en) 1996-02-28
AU670194B2 (en) 1996-07-04
EP0646004A1 (en) 1995-04-05
IL109235A (en) 1998-09-24
NO944809L (en) 1994-12-12
HU9500120D0 (en) 1995-03-28
UA42693C2 (en) 2001-11-15
NO307126B1 (en) 2000-02-14
AU6537194A (en) 1994-11-08
GB9307948D0 (en) 1993-06-02
IL109235A0 (en) 1994-07-31
CZ10795A3 (en) 1995-09-13
CA2137148A1 (en) 1994-10-27
NO944809D0 (en) 1994-12-12
PL306798A1 (en) 1995-04-18
TW308593B (en) 1997-06-21
CZ282988B6 (en) 1997-12-17
JPH07508044A (en) 1995-09-07

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