RU2353380C2 - Drug for inflammatory process prevention and treatment - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to chemical-pharmaceutical industry. A drug for inflammatory process prevention and treatment in an animal contains sea-buckthorn oil, 0.9% sterile salt brine, bactericidal lamp annealed and reduced to amorphous powder, mixed peppermint dry leaves, caulis and bloom, swallowwort fruits, dry pot marigold bloom, dry horse gowan bloom, dry common plantain leaves, dry costmary bloom, and formalin in certain ratio. The drug can be lanolin ointment in ratio 1:1.

EFFECT: drug ensured the most rapid recovery of physiological status.

2 cl

Description

The present invention relates to veterinary medicine.

Long-term use of herbal medicines in traditional medicine and official medical practice is known. They were prescribed and are prescribed in tinctures, infusions, decoctions, ointments and in other dosage forms. Each of herbal medicines has one or more of the most pronounced healing properties, but none of them has many properties with different strengths, but in one direction, properties.

The purpose of the invention is the creation of a drug with versatile effects in the prevention and treatment of inflammatory processes in damaged parts of the animal’s body.

This goal is achieved by using a product containing sea buckthorn oil, a 0.9% sterile solution of sodium chloride, a mixture treated with a bactericidal lamp and crushed to an amorphous powder of dried leaves, stems and flowers of peppermint, dried leaves, flowers and fruits of celandine large, dried flower baskets of medicinal marigolds, dry chamomile flowers of a pharmacy, dry leaves of plantain large, dry flower baskets of tansy and formalin, with the following ingredients in g: oil blind buckthorn - 100.0, 0.9% sterile sodium chloride solution - 200.0, powder of dry leaves, stems and flowers of peppermint - 15.0, powder of dry leaves, flowers and fruits of large celandine - 15.0, powder dried flower baskets of medicinal marigolds - 10.0, powder of dried chamomile flowers for pharmacy - 10.0, powder of dry leaves of plantain large - 10.0, powder of dried flower baskets of tansy ordinary - 16.0, formalin - 2.5, and it can be made in the form of an ointment on a lanolin base with a ratio of 1: 1.

When cooking, the chopped vegetable raw materials treated for half an hour with the rays of a bactericidal lamp are poured while stirring with sea buckthorn oil, 0.9% sterile sodium chloride solution, formalin and insisted for 15 days at room temperature and stirring, the drug is used orally for gastritis, enteritis, colitis and other diseases of an inflammatory nature, accompanied by painful colic, as an anthelmintic for ascariasis and pinworms in piglets, as a means of increasing digestive secretion glands, the drug is used externally in the treatment of fresh, inflamed, and zoophilic fly wounds infested with larvae of the body, as a means of stimulating the growth of granulation tissue cells and normal cells in malignant neoplasms (4, p. 328).

The mechanism of action of the ingredients of the drug;

- sea buckthorn oil - an oily orange-red liquid with a characteristic odor and taste, contains many fat-soluble medicinal substances, such as karate and karatinoids, tocopherols, glycerides of oleic, linoleic, palmetic, stearic and other acids. In addition to this, sea-buckthorn oil in the preparation also contains esters, provitamins and other substances extracted from plant raw materials of the preparation. When a pathological process enters a site, they contribute to the activation of regenerative processes in tissue cells, act bactericidal, emollient, promote the transition of provitamins to an active state and their assimilation by the body (2, vol. 2, p. 47);

- 0.9% sterile sodium chloride solution extracts water-soluble medicinal, tanning, painkillers and other substances from plant raw materials, contains, in addition to sodium, other mineral substances necessary for the cells of the tissue lesion foci;

- dry stems, leaves and flowers of peppermint contain essential oils with 1-menthol, 1-menton, alpha and beta pipenes, 1-limenene, alpha-felandron, menthol esters with acetic and valerianic acids, mentofuran, carotene and other substances . They in the infusion have an antispasmodic and analgesic effect, have antiseptic and many other properties (1, p.171-179; 2, t.1, p.346-349; 4, p.188-191);

- the leaves, stems, flowers and fruits of the large celandine contain more than 20 alkaloids, essential oil, a lot of ascorbic acid, carotene, flavonoids, saponins, organic acids, resinous substances, etc.

In the experiment, large celandine preparations cause growth retardation of malignant neoplasms, have fungistatic, bacteriostatic, and analgesic effects; they have anti-inflammatory effects in gastric cancer and relieve pain (1, p. 260-263; 4, p. 326-329);

- dry flower baskets of medicinal marigolds (calendula) in infusions and ointments have anti-inflammatory, bactericidal, hypotensive effects, have a soothing effect on the central nervous system, in ointments they have long been used to treat various body injuries, during frostbite, burns, with furunculosis, in the treatment of erosion, trichomonas colpitis, proctitis, paraproctitis (4, p.197-200);

- dry chamomile pharmacy flowers contain essential oil containing chamazulene, azulene, antemisic acid, glucosides and other therapeutic substances. Infusions of chamomile pharmacy flowers have a pronounced anti-inflammatory, anti-allergic, disinfectant, sodative, anesthetic effect, accelerate cell growth and development, have an antispasmodic effect (1, p. 211-214; 2, t. 1-st, p. 341, 4, s .247-250);

- dry leaves of large plantain contains glucoside rhinatin, carotene, vitamins K and C, tannins, alkaloids, polysaccharides and other substances. They in tinctures have anti-inflammatory, bacteriostatic, wound healing, anti-allergic, antispasmodic effects (1, p.191-194; 2, t.2-nd, p.363, 4, p.232-234);

- flower baskets of tansy common contain essential oil which includes alpha thujone, beta camphor, thujol, borneol, pinene and others. In infusions, when interacting with the tissues of a diseased part of the animal’s body, they exert an antimicrobial, anti-inflammatory effect, are harmful, and if they interact for a long time, they are detrimental to the larvae of bestial flies in the wound and have a toxic effect on roundworm and pinworms (1, p. 4, p. 224-227);

- formalin - a clear liquid with a peculiar pungent odor, has antimicrobial, deodorizing, harmful to the larvae of flies in the wound and repel flies from the wound action (3, p. 474-477).

Thus, the proposed drug contains a significant amount of therapeutic substances. Many of them act in one direction, but different in strength, place and direction of action. As a result of this simultaneous multifaceted and multidirectional action, the development of the inflammatory process is prevented in fresh wounds, the development of microorganisms is prevented in inflamed wounds, and granulation and regeneration of tissue cells are accelerated in a relatively short time.

During experimental tests, it was determined that after treating the wound with a liquid preparation or ointment, flies do not sit on it for up to 2 hours, a fresh medium-sized tissue defect is filled with granulation tissue in one to two days, inflamed within 4-6 days, invaded by zoophilic larvae flies - by the end of the 6-9th day, after giving the piglets of the group 2-4 months of the liquid part of the drug inside, their general clinical condition improves by the end of the second day.

We believe that the proposed drug will be widely used in veterinary medicine in the prevention of the development and treatment of inflammatory processes in animals.

Literature

1. Kovaleva N.G. Treatment with plants. M., Medicine, 1971

2. Mashkovsky A.D. Medicinal substances. M., Medicine, volumes 1 and 2, 1987

3. Brains I.E. Pharmacology. M., Selkhozizdat, 1954

4. Schröter A.I., Muravyova D.A., Pakaln D.A., Efimova F.V. Medicinal flora of the Caucasus. M., Medicine, 1979

Claims (2)

1. Means for preventing the development and treatment of inflammatory processes in the animal’s body, including the use of herbal medicinal substances, characterized in that the product contains sea buckthorn oil, 0.9% sterile sodium chloride solution, a mixture treated with a bactericidal lamp and ground to an amorphous powder dry leaves, stalks and flowers of peppermint, dry leaves, flowers and fruits of celandine large, dried flower baskets of medicinal marigolds, dry flowers of a pharmacy chamomile, dry leaves under plantain of a large, dry flower basket of tansy and formalin with the following ingredients, g:
sea buckthorn oil 100.0 0.9% sterile sodium chloride solution 200,0 powder of dry leaves, stems and flowers peppermint 15.0 powder of dried leaves, flowers and fruits large celandine 15.0 dried flower basket powder marigold medicinal 10.0 dry powder of chamomile pharmacy flowers 10.0 powder of dry leaves of large plantain 10.0 dry flower basket powder tansy 15.0 formalin 2.5 2. The tool according to claim 1, characterized in that it can be made in the form of an ointment on a lanolin base with a ratio of 1: 1.