RU2019102890A - Фармацевтические композиции, содержащие флурбипрофен - Google Patents
Фармацевтические композиции, содержащие флурбипрофен Download PDFInfo
- Publication number
- RU2019102890A RU2019102890A RU2019102890A RU2019102890A RU2019102890A RU 2019102890 A RU2019102890 A RU 2019102890A RU 2019102890 A RU2019102890 A RU 2019102890A RU 2019102890 A RU2019102890 A RU 2019102890A RU 2019102890 A RU2019102890 A RU 2019102890A
- Authority
- RU
- Russia
- Prior art keywords
- nsaid
- cough
- use according
- treatment
- amount
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 11
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 9
- 206010011224 Cough Diseases 0.000 claims 6
- SYTBZMRGLBWNTM-UHFFFAOYSA-N flurbiprofen Chemical compound FC1=CC(C(C(O)=O)C)=CC=C1C1=CC=CC=C1 SYTBZMRGLBWNTM-UHFFFAOYSA-N 0.000 claims 2
- 229960002390 flurbiprofen Drugs 0.000 claims 2
- 239000007909 solid dosage form Substances 0.000 claims 2
- 230000001055 chewing effect Effects 0.000 claims 1
- 208000017574 dry cough Diseases 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000004400 mucous membrane Anatomy 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Claims (8)
1. Применение нестероидного противовоспалительного средства (НПВС) флурбипрофена или его фармацевтически приемлемой соли в местном лечении кашля на слизистой оболочке горла пациента, нуждающегося в лечении кашля.
2. Применение по п.1, где использование осуществляется для лечения сухого кашля.
3. Применение по п.1, где НПВС используется в количестве от 2 до 30 мг на одну дозу НПВС.
4. Применение по п.3, где НПВС используется в количестве от 2,5 до 30 мг на одну дозу НПВС.
5. Применение по п.4, где НПВС используется в количестве от 5 до 15 мг на одну дозу НПВС.
6. Применение по п.1, где НПВС вводится пациенту, нуждающемуся в лечении кашля, как композиция в форме твердой лекарственной формы для разжевывания или рассасывания или жидкости.
7. Применение по п.6, где твердая лекарственная форма представляет собой пастилку или гранулу.
8. Способ местного лечения кашля, включающий введение терапевтически эффективного количества нестероидного противовоспалительного средства (НПВС) флурбипрофена на внутреннюю поверхность горла пациента, нуждающегося в лечении кашля.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261697901P | 2012-09-07 | 2012-09-07 | |
| GB1215988.5 | 2012-09-07 | ||
| GBGB1215988.5A GB201215988D0 (en) | 2012-09-07 | 2012-09-07 | Pharmaceutical compositions comprising flurbiprofen |
| US61/697,901 | 2012-09-07 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015112586A Division RU2015112586A (ru) | 2012-09-07 | 2013-09-09 | Фармацевтические композиции, содержащие флурбипрофен |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2019102890A true RU2019102890A (ru) | 2019-05-07 |
Family
ID=47137098
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019102890A RU2019102890A (ru) | 2012-09-07 | 2013-09-09 | Фармацевтические композиции, содержащие флурбипрофен |
| RU2015112586A RU2015112586A (ru) | 2012-09-07 | 2013-09-09 | Фармацевтические композиции, содержащие флурбипрофен |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015112586A RU2015112586A (ru) | 2012-09-07 | 2013-09-09 | Фармацевтические композиции, содержащие флурбипрофен |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US20150231063A1 (ru) |
| EP (1) | EP2892528B1 (ru) |
| KR (2) | KR20200131913A (ru) |
| AU (1) | AU2013312259B2 (ru) |
| BR (1) | BR112015004115A2 (ru) |
| ES (1) | ES2742034T3 (ru) |
| GB (1) | GB201215988D0 (ru) |
| MX (1) | MX363558B (ru) |
| PL (1) | PL2892528T3 (ru) |
| RU (2) | RU2019102890A (ru) |
| WO (1) | WO2014039939A1 (ru) |
| ZA (1) | ZA201501553B (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11007161B1 (en) | 2014-12-31 | 2021-05-18 | Eric Morrison | Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films |
| US10596117B1 (en) | 2014-12-31 | 2020-03-24 | Eric Morrison | Lipoleosomes as carriers for aromatic amide anesthetic compounds |
| US10561627B2 (en) | 2014-12-31 | 2020-02-18 | Eric Morrison | Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5025019A (en) * | 1984-04-09 | 1991-06-18 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| US5322689A (en) * | 1992-03-10 | 1994-06-21 | The Procter & Gamble Company | Topical aromatic releasing compositions |
| US20030206942A1 (en) | 1998-09-25 | 2003-11-06 | Neema Kulkarni | Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent |
| US6846495B2 (en) * | 1999-01-11 | 2005-01-25 | The Procter & Gamble Company | Compositions having improved delivery of actives |
| US20060241175A1 (en) * | 2002-09-27 | 2006-10-26 | Joseph Schwarz | Vehicle for topical delivery of anti-inflammatory compounds |
| GB2423710A (en) | 2005-03-01 | 2006-09-06 | Boots Healthcare Int Ltd | Lozenge production process |
| EP2106258B1 (de) * | 2006-10-20 | 2012-09-12 | Bayer Consumer Care AG | Ibuprofen gegen husten |
| GB2453770A (en) * | 2007-10-19 | 2009-04-22 | Reckitt Benckiser Healthcare | Oral composition comprising a cooling agent |
| RU2640921C2 (ru) * | 2010-09-29 | 2018-01-12 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
| GB201021267D0 (en) | 2010-12-15 | 2011-01-26 | Reckitt Benckiser Healthcare Int Ltd | Novel pharmaceutical formulation |
-
2012
- 2012-09-07 GB GBGB1215988.5A patent/GB201215988D0/en not_active Ceased
-
2013
- 2013-09-09 ES ES13836176T patent/ES2742034T3/es active Active
- 2013-09-09 MX MX2015002946A patent/MX363558B/es unknown
- 2013-09-09 BR BR112015004115A patent/BR112015004115A2/pt not_active Application Discontinuation
- 2013-09-09 AU AU2013312259A patent/AU2013312259B2/en active Active
- 2013-09-09 RU RU2019102890A patent/RU2019102890A/ru unknown
- 2013-09-09 US US14/424,820 patent/US20150231063A1/en not_active Abandoned
- 2013-09-09 RU RU2015112586A patent/RU2015112586A/ru unknown
- 2013-09-09 EP EP13836176.1A patent/EP2892528B1/en not_active Revoked
- 2013-09-09 KR KR1020207032730A patent/KR20200131913A/ko not_active IP Right Cessation
- 2013-09-09 KR KR1020157008886A patent/KR20150048890A/ko not_active Application Discontinuation
- 2013-09-09 PL PL13836176T patent/PL2892528T3/pl unknown
- 2013-09-09 WO PCT/US2013/058685 patent/WO2014039939A1/en active Application Filing
-
2015
- 2015-03-06 ZA ZA2015/01553A patent/ZA201501553B/en unknown
-
2017
- 2017-12-19 US US15/846,613 patent/US20180110723A1/en not_active Abandoned
-
2018
- 2018-11-02 US US16/179,552 patent/US20190070101A1/en not_active Abandoned
-
2020
- 2020-01-31 US US16/778,576 patent/US20200163871A1/en not_active Abandoned
-
2021
- 2021-09-27 US US17/486,308 patent/US20220008331A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX363558B (es) | 2019-03-27 |
| EP2892528A4 (en) | 2016-04-13 |
| BR112015004115A2 (pt) | 2017-07-04 |
| WO2014039939A1 (en) | 2014-03-13 |
| US20190070101A1 (en) | 2019-03-07 |
| EP2892528A1 (en) | 2015-07-15 |
| US20180110723A1 (en) | 2018-04-26 |
| MX2015002946A (es) | 2015-06-02 |
| AU2013312259B2 (en) | 2018-06-07 |
| GB201215988D0 (en) | 2012-10-24 |
| AU2013312259A1 (en) | 2015-04-09 |
| US20220008331A1 (en) | 2022-01-13 |
| US20200163871A1 (en) | 2020-05-28 |
| RU2015112586A (ru) | 2016-10-27 |
| ES2742034T3 (es) | 2020-02-12 |
| EP2892528B1 (en) | 2019-05-15 |
| US20150231063A1 (en) | 2015-08-20 |
| KR20150048890A (ko) | 2015-05-07 |
| PL2892528T3 (pl) | 2019-11-29 |
| ZA201501553B (en) | 2017-08-30 |
| KR20200131913A (ko) | 2020-11-24 |
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