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RS64362B1 - Postupak za pripremu 2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h-pirazol-5-il)-1,7-naftiridina - Google Patents

Postupak za pripremu 2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h-pirazol-5-il)-1,7-naftiridina

Info

Publication number
RS64362B1
RS64362B1 RS20230548A RSP20230548A RS64362B1 RS 64362 B1 RS64362 B1 RS 64362B1 RS 20230548 A RS20230548 A RS 20230548A RS P20230548 A RSP20230548 A RS P20230548A RS 64362 B1 RS64362 B1 RS 64362B1
Authority
RS
Serbia
Prior art keywords
pyrazol
methylmorpholin
naphthyridine
methyl
preparing
Prior art date
Application number
RS20230548A
Other languages
English (en)
Inventor
Johannes Platzek
Philipp Rubenbauer
Der Haas Hendricus Nicolaas Sebastiaan Van
Sonja Elisabeth Hoogeveen
Oers Matthijs Cornelis Maria Van
Reinerus Gerardus Gieling
Jeroen Alexander Dekker
Original Assignee
Bayer Ag
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Bayer Pharma AG filed Critical Bayer Ag
Publication of RS64362B1 publication Critical patent/RS64362B1/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
RS20230548A 2018-08-24 2019-08-22 Postupak za pripremu 2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h-pirazol-5-il)-1,7-naftiridina RS64362B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18190731 2018-08-24
PCT/EP2019/072467 WO2020039025A1 (en) 2018-08-24 2019-08-22 Method for preparing 2-[(3r)-3-methylmorpholin-4-yl]-4-[1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-5-yl)-1,7-naphthyridine
EP19759528.3A EP3841101B1 (en) 2018-08-24 2019-08-22 Method for preparing 2-[(3r)-3-methylmorpholin-4-yl]-4-[1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-5-yl)-1,7-naphthyridine

Publications (1)

Publication Number Publication Date
RS64362B1 true RS64362B1 (sr) 2023-08-31

Family

ID=63405064

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20230548A RS64362B1 (sr) 2018-08-24 2019-08-22 Postupak za pripremu 2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h-pirazol-5-il)-1,7-naftiridina

Country Status (27)

Country Link
US (1) US20210253573A1 (sr)
EP (1) EP3841101B1 (sr)
JP (1) JP7422741B2 (sr)
KR (1) KR20210049845A (sr)
CN (1) CN112823158B (sr)
AU (1) AU2019324521B9 (sr)
BR (1) BR112021001309A2 (sr)
CA (1) CA3110394A1 (sr)
CL (1) CL2021000454A1 (sr)
CO (1) CO2021001892A2 (sr)
DK (1) DK3841101T3 (sr)
ES (1) ES2950825T3 (sr)
FI (1) FI3841101T3 (sr)
HR (1) HRP20230611T1 (sr)
HU (1) HUE062332T2 (sr)
IL (1) IL280878A (sr)
JO (1) JOP20210032A1 (sr)
LT (1) LT3841101T (sr)
MX (1) MX2021002132A (sr)
PE (1) PE20210862A1 (sr)
PL (1) PL3841101T3 (sr)
PT (1) PT3841101T (sr)
RS (1) RS64362B1 (sr)
SG (1) SG11202101011RA (sr)
SI (1) SI3841101T1 (sr)
UA (1) UA128407C2 (sr)
WO (1) WO2020039025A1 (sr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI700283B (zh) 2014-08-04 2020-08-01 德商拜耳製藥公司 ２-(嗎啉-４-基)-１,７-萘啶
US11690911B2 (en) 2017-08-04 2023-07-04 Bayer Aktiengesellschaft Combination of ATR kinase inhibitors and PD-1/PD-L1 inhibitors
US11236070B2 (en) 2019-05-16 2022-02-01 Novartis Ag Chemical process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007107469A1 (en) * 2006-03-20 2007-09-27 F. Hoffmann-La Roche Ag Methods of inhibiting btk and syk protein kinases
WO2008150827A1 (en) * 2007-05-29 2008-12-11 Smithkline Beecham Corporation Naphthyridine, derivatives as p13 kinase inhibitors
US8735424B2 (en) * 2008-09-02 2014-05-27 Novartis Ag Bicyclic kinase inhibitors
AU2012257513B2 (en) * 2011-05-19 2017-05-11 Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Macrocyclic compounds as protein kinase inhibitors
KR101366368B1 (ko) * 2011-07-08 2014-02-21 주식회사 두산 신규 유기 전계 발광 화합물 및 이를 포함하는 유기 전계 발광 소자
TWI700283B (zh) 2014-08-04 2020-08-01 德商拜耳製藥公司 ２-(嗎啉-４-基)-１,７-萘啶
WO2018153970A1 (en) * 2017-02-24 2018-08-30 Bayer Pharma Aktiengesellschaft Solid forms of 2-[(3r)-3-methylmorpholin-4-yl]-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-5-yl)-1,7-naphthyridine

Also Published As

Publication number Publication date
LT3841101T (lt) 2023-06-26
EP3841101A1 (en) 2021-06-30
SI3841101T1 (sl) 2023-07-31
EP3841101B1 (en) 2023-05-03
FI3841101T3 (fi) 2023-07-28
HUE062332T2 (hu) 2023-10-28
HRP20230611T1 (hr) 2023-09-15
AU2019324521A1 (en) 2021-03-11
IL280878A (en) 2021-04-29
PT3841101T (pt) 2023-07-25
CL2021000454A1 (es) 2021-07-09
SG11202101011RA (en) 2021-02-25
ES2950825T3 (es) 2023-10-13
JOP20210032A1 (ar) 2021-02-23
AU2019324521B2 (en) 2024-10-31
CN112823158B (zh) 2023-08-15
UA128407C2 (uk) 2024-07-03
CA3110394A1 (en) 2020-02-27
KR20210049845A (ko) 2021-05-06
PL3841101T3 (pl) 2023-08-21
WO2020039025A1 (en) 2020-02-27
US20210253573A1 (en) 2021-08-19
CO2021001892A2 (es) 2021-03-08
JP2021535122A (ja) 2021-12-16
CN112823158A (zh) 2021-05-18
DK3841101T3 (da) 2023-07-31
AU2019324521B9 (en) 2024-11-14
PE20210862A1 (es) 2021-05-18
MX2021002132A (es) 2021-04-28
BR112021001309A2 (pt) 2021-04-27
JP7422741B2 (ja) 2024-01-26

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