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RS55697B1 - Donori nitroksila za lečenje plućne hipertenzije - Google Patents

Donori nitroksila za lečenje plućne hipertenzije

Info

Publication number
RS55697B1
RS55697B1 RS20170138A RSP20170138A RS55697B1 RS 55697 B1 RS55697 B1 RS 55697B1 RS 20170138 A RS20170138 A RS 20170138A RS P20170138 A RSP20170138 A RS P20170138A RS 55697 B1 RS55697 B1 RS 55697B1
Authority
RS
Serbia
Prior art keywords
treatment
nitroxyl donors
lung hypertension
hypertension
lung
Prior art date
Application number
RS20170138A
Other languages
English (en)
Inventor
Vincent J Kalish
Reza Mazhari
Original Assignee
Cardioxyl Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardioxyl Pharmaceuticals Inc filed Critical Cardioxyl Pharmaceuticals Inc
Publication of RS55697B1 publication Critical patent/RS55697B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20170138A 2009-11-23 2010-11-23 Donori nitroksila za lečenje plućne hipertenzije RS55697B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26369809P 2009-11-23 2009-11-23
US26412909P 2009-11-24 2009-11-24
EP10784416.9A EP2504003B1 (en) 2009-11-23 2010-11-23 Nitroxyl donors for the treatment of pulmonary hypertension
PCT/US2010/057844 WO2011063400A1 (en) 2009-11-23 2010-11-23 Nitroxyl donors for the treatment of pulmonary hypertension

Publications (1)

Publication Number Publication Date
RS55697B1 true RS55697B1 (sr) 2017-07-31

Family

ID=43513876

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20170138A RS55697B1 (sr) 2009-11-23 2010-11-23 Donori nitroksila za lečenje plućne hipertenzije

Country Status (15)

Country Link
US (2) US20110160200A1 (sr)
EP (1) EP2504003B1 (sr)
JP (2) JP2013511556A (sr)
CY (1) CY1118603T1 (sr)
DK (1) DK2504003T3 (sr)
ES (1) ES2611852T3 (sr)
HR (1) HRP20170183T1 (sr)
HU (1) HUE032253T2 (sr)
LT (1) LT2504003T (sr)
PL (1) PL2504003T3 (sr)
PT (1) PT2504003T (sr)
RS (1) RS55697B1 (sr)
SI (1) SI2504003T1 (sr)
SM (2) SMT201700090T1 (sr)
WO (2) WO2011063339A1 (sr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2509941B1 (en) * 2009-12-07 2019-01-23 The Johns Hopkins University N-acylated hydroxylamine derivatives and o-acylated hydroxylamine derivatives
AU2010328230B2 (en) * 2009-12-07 2016-06-02 Cardioxyl Pharmaceuticals, Inc. Bis-acylated hydroxylamine derivatives
US9181213B2 (en) 2011-10-17 2015-11-10 The Johns Hopkins University Meldrum's acid, barbituric acid and pyrazolone derivatives substituted with hydroxylamine as HNO donors
EP2945620B1 (en) 2013-01-18 2017-11-22 Cardioxyl Pharmaceuticals, Inc. Nitroxyl donors with improved therapeutic index
AU2014267360B2 (en) 2013-05-14 2018-07-05 Active Biotech Ab N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors
ES2734060T3 (es) 2014-01-17 2019-12-04 Cardioxyl Pharmaceuticals Inc Donadores de nitroxilo de N-hidroximetanosulfonamida
US9682938B2 (en) 2014-05-27 2017-06-20 Cardioxyl Pharmaceuticals, Inc. Pyrazolone derivatives as nitroxyl donors
US9464061B2 (en) 2014-05-27 2016-10-11 The Johns Hopkins University N-hydroxylamino-barbituric acid derivatives
WO2017070084A1 (en) 2015-10-19 2017-04-27 Cardioxyl Pharmaceuticals, Inc. N-hydroxylsulfonamide derivatives as nitroxyl donors
KR20180063326A (ko) 2015-10-19 2018-06-11 카르디옥실 파마슈티칼스 인코포레이티드 니트록실 공여자로서의 피라졸론 유도체
CN110139854A (zh) 2016-07-28 2019-08-16 约翰斯霍普金斯大学 O-取代异羟肟酸
AU2018205621B2 (en) 2017-01-03 2023-01-05 Cardioxyl Pharmaceuticals, Inc. Method of administering nitroxyl donating compounds

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Also Published As

Publication number Publication date
JP2013511556A (ja) 2013-04-04
WO2011063339A1 (en) 2011-05-26
DK2504003T3 (en) 2017-02-20
SI2504003T1 (sl) 2017-01-31
EP2504003A1 (en) 2012-10-03
HRP20170183T1 (hr) 2017-03-24
PL2504003T3 (pl) 2017-04-28
WO2011063400A1 (en) 2011-05-26
EP2504003B1 (en) 2016-11-09
PT2504003T (pt) 2017-01-31
CY1118603T1 (el) 2017-07-12
HUE032253T2 (en) 2017-09-28
JP2016128481A (ja) 2016-07-14
US20110160200A1 (en) 2011-06-30
US20160081951A1 (en) 2016-03-24
SMT201700090B (it) 2017-03-08
LT2504003T (lt) 2017-01-25
SMT201700090T1 (it) 2017-03-08
ES2611852T3 (es) 2017-05-10

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