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RS50516B - Prečišćavanje il-18 vezujućeg proteina - Google Patents

Prečišćavanje il-18 vezujućeg proteina

Info

Publication number
RS50516B
RS50516B RSP-2007/0216A RSP20070216A RS50516B RS 50516 B RS50516 B RS 50516B RS P20070216 A RSP20070216 A RS P20070216A RS 50516 B RS50516 B RS 50516B
Authority
RS
Serbia
Prior art keywords
binding protein
purification
charge
application contains
hydrophobic chromatography
Prior art date
Application number
RSP-2007/0216A
Other languages
English (en)
Inventor
Mara Rossi
Thierry Ziegler
Laure Valognes
Original Assignee
Ares Trading S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading S.A. filed Critical Ares Trading S.A.
Publication of RS50516B publication Critical patent/RS50516B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Upotreba hidrofobne hromatografije sa indukcijom naelektrisanja za produkciju purifikovanog IL-18 vezujućeg proteina (IL-18BP). Prijava sadrži 1+20 patentnih zahteva.
RSP-2007/0216A 2003-11-05 2004-11-04 Prečišćavanje il-18 vezujućeg proteina RS50516B (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51744703P 2003-11-05 2003-11-05
EP03104092 2003-11-05
PCT/EP2004/052807 WO2005049649A1 (en) 2003-11-05 2004-11-04 Process for the purification of il-18 binding protein

Publications (1)

Publication Number Publication Date
RS50516B true RS50516B (sr) 2010-05-07

Family

ID=34924126

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2007/0216A RS50516B (sr) 2003-11-05 2004-11-04 Prečišćavanje il-18 vezujućeg proteina

Country Status (19)

Country Link
US (1) US7820800B2 (sr)
EP (1) EP1689777B1 (sr)
JP (1) JP4741504B2 (sr)
AT (1) ATE360647T1 (sr)
AU (1) AU2004291341B2 (sr)
CA (1) CA2544146C (sr)
CY (1) CY1106683T1 (sr)
DE (1) DE602004006157T2 (sr)
DK (1) DK1689777T3 (sr)
ES (1) ES2285543T3 (sr)
HR (1) HRP20070196T3 (sr)
IL (1) IL175431A (sr)
ME (1) ME01198B (sr)
NO (1) NO330538B1 (sr)
PL (1) PL1689777T3 (sr)
PT (1) PT1689777E (sr)
RS (1) RS50516B (sr)
SI (1) SI1689777T1 (sr)
WO (1) WO2005049649A1 (sr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004081167A2 (en) 2003-03-11 2004-09-23 Applied Research Systems Ars Holding N.V. Expression vectors comprising the mcmv ie2 promoter
US20080076708A1 (en) * 2003-05-13 2008-03-27 Valter Altarocca Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
AU2004284243B2 (en) 2003-10-21 2010-11-04 Merck Serono Sa Minimal DNA sequence acting as a chromatin insulator and its use in protein expression
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
PT1720979E (pt) 2004-03-01 2007-10-25 Ares Trading Sa Utilização de um meio de cultura de células sem soro para a produção de il-18bp em células de mamífero
WO2006003134A1 (en) * 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
US8129508B2 (en) 2005-04-11 2012-03-06 Medarex, Inc. Protein purification using HCIC and ion exchange chromatography
DK1885753T3 (da) 2005-06-03 2011-10-03 Ares Trading Sa Fremstilling af rekombinant II-18-proteiner
PT1891088E (pt) 2005-06-10 2011-12-19 Ares Trading Sa Processo para a purificação da proteína de ligação il-18
US9096651B2 (en) 2007-09-26 2015-08-04 Chugai Seiyaku Kabushiki Kaisha Method of modifying isoelectric point of antibody via amino acid substitution in CDR
CA2711375C (en) 2008-01-18 2019-04-16 F. Hoffmann-La Roche Ag Purification of not-glycosylated polypeptides
TR201808046T4 (tr) 2008-04-11 2018-06-21 Chugai Pharmaceutical Co Ltd İki veya daha fazla sayıda antijen molekülüne tekrar tekrar bağlanabilen antijen bağlanma molekülü.
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
WO2011156369A2 (en) * 2010-06-07 2011-12-15 Dr. Reddy's Laboratories Ltd. Purification of modified cytokines
RU2642318C2 (ru) 2010-11-30 2018-01-24 Чугаи Сейяку Кабусики Кайся Антигенсвязывающая молекула, способная многократно связываться с множеством антигенных молекул
EP2679681B2 (en) 2011-02-25 2023-11-15 Chugai Seiyaku Kabushiki Kaisha FcgammaRIIB-specific FC antibody
JP6147726B2 (ja) 2011-03-29 2017-06-14 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ タンパク質精製のためのバッファー系
EP2762493B1 (en) 2011-09-30 2021-06-09 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
TW201817744A (zh) 2011-09-30 2018-05-16 日商中外製藥股份有限公司 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
CN113416257A (zh) 2011-11-30 2021-09-21 中外制药株式会社 包含进入细胞内以形成免疫复合体的搬运体(载体)的药物
MX2015014017A (es) 2013-04-02 2016-02-10 Chugai Pharmaceutical Co Ltd Variante de la region fc.
PL3116891T3 (pl) * 2014-03-10 2020-07-27 Richter Gedeon Nyrt. Oczyszczanie immunoglobuliny z zastosowaniem etapów wstępnego oczyszczania
EP3233230B1 (en) 2014-12-15 2024-06-12 Merck Patent GmbH Target molecule capture from crude solutions
MY181199A (en) 2014-12-19 2020-12-21 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
HUE056489T2 (hu) 2014-12-19 2022-02-28 Chugai Pharmaceutical Co Ltd Anti-C5 antitestek és alkalmazási eljárások
EA201791754A1 (ru) 2015-02-05 2019-01-31 Чугаи Сейяку Кабусики Кайся АНТИТЕЛА, СОДЕРЖАЩИЕ ЗАВИСЯЩИЙ ОТ КОНЦЕНТРАЦИИ ИОНОВ АНТИГЕНСВЯЗЫВАЮЩИЙ ДОМЕН, ВАРИАНТЫ Fc-ОБЛАСТИ, IL-8-СВЯЗЫВАЮЩИЕ АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
JP6130983B2 (ja) 2015-02-27 2017-05-17 中外製薬株式会社 Ｉｌ−６関連疾患治療用組成物
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
KR102538749B1 (ko) 2016-08-05 2023-06-01 추가이 세이야쿠 가부시키가이샤 Il-8 관련 질환의 치료용 또는 예방용 조성물
WO2018139623A1 (en) 2017-01-30 2018-08-02 Chugai Seiyaku Kabushiki Kaisha Anti-sclerostin antibodies and methods of use
US11851486B2 (en) 2017-05-02 2023-12-26 National Center Of Neurology And Psychiatry Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
KR100537558B1 (ko) 1998-09-01 2005-12-19 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 인터류킨-18 결합 단백질
JP4216950B2 (ja) * 1998-09-01 2009-01-28 株式会社林原生物化学研究所 インターロイキン−１８結合蛋白質
US20020052475A1 (en) * 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor
ATE315647T1 (de) * 2001-03-08 2006-02-15 Ares Trading Sa Interleukin -18 mutantenproteine, deren herstellung und verwendung
DE60235989D1 (de) * 2001-06-26 2010-05-27 Amgen Fremont Inc Antikörper gegen opgl
US20040018573A1 (en) * 2002-04-18 2004-01-29 Power Scott D Production of functional antibodies in filamentous fungi
WO2004081167A2 (en) 2003-03-11 2004-09-23 Applied Research Systems Ars Holding N.V. Expression vectors comprising the mcmv ie2 promoter
US20080076708A1 (en) 2003-05-13 2008-03-27 Valter Altarocca Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
AU2004284243B2 (en) 2003-10-21 2010-11-04 Merck Serono Sa Minimal DNA sequence acting as a chromatin insulator and its use in protein expression
PT1720979E (pt) 2004-03-01 2007-10-25 Ares Trading Sa Utilização de um meio de cultura de células sem soro para a produção de il-18bp em células de mamífero
WO2006003134A1 (en) 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
DK1885753T3 (da) * 2005-06-03 2011-10-03 Ares Trading Sa Fremstilling af rekombinant II-18-proteiner
PT1891088E (pt) 2005-06-10 2011-12-19 Ares Trading Sa Processo para a purificação da proteína de ligação il-18

Also Published As

Publication number Publication date
US7820800B2 (en) 2010-10-26
WO2005049649A1 (en) 2005-06-02
NO330538B1 (no) 2011-05-09
NO20062545L (no) 2006-08-03
SI1689777T1 (sl) 2007-08-31
ME01198B (me) 2013-03-20
CY1106683T1 (el) 2012-05-23
JP4741504B2 (ja) 2011-08-03
IL175431A0 (en) 2006-09-05
HRP20070196T3 (en) 2007-06-30
PT1689777E (pt) 2007-05-31
DE602004006157D1 (de) 2007-06-06
DK1689777T3 (da) 2007-06-11
IL175431A (en) 2011-02-28
ES2285543T3 (es) 2007-11-16
EP1689777B1 (en) 2007-04-25
JP2007533651A (ja) 2007-11-22
ATE360647T1 (de) 2007-05-15
CA2544146A1 (en) 2005-06-02
AU2004291341B2 (en) 2010-08-05
DE602004006157T2 (de) 2008-01-03
AU2004291341A1 (en) 2005-06-02
US20070037734A1 (en) 2007-02-15
PL1689777T3 (pl) 2007-09-28
EP1689777A1 (en) 2006-08-16
CA2544146C (en) 2012-10-02

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